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The map label for this gene is ttuD [H]

Identifier: 225851899

GI number: 225851899

Start: 387584

End: 388870

Strand: Direct

Name: ttuD [H]

Synonym: BMEA_A0392

Alternate gene names: 225851899

Gene position: 387584-388870 (Clockwise)

Preceding gene: 225851898

Following gene: 225851909

Centisome position: 18.23

GC content: 61.93

Gene sequence:

>1287_bases
ATGTCCGCCATCGCCGATCCGAAAAAGTTCCTGACCAGCCTCTTCGATGCAGCCGTCGCGGCGGCTGATCCTGAGCTGGT
GATCCGCGCGAACCTGCCTGAAAAGCCGAAAGGGCGTACCATCGTCATCGGGGCGGGCAAGGGTTCTGCGCAAATGGCGG
CGGCTTTCGAGCGCGCCTGGGCTGAAAAACATGATGCACCGCTGGAAGGCGTGGTGGTCACGCGCTATGGCTATGGTGCT
CCCTGCGAGCGCATCAGGATCATCGAGGCCGCGCATCCGGTTCCAGACGGCGCGGGGCTTGCGGCTTCCAGACGGCTGTT
CAATGCCGTGTCCGGGTTGAGTGAAGACGATCTTGTGGTGGCGCTTATCTCCGGCGGCGGATCGGCCCTGCTACCGTCAC
CGCCCGAAGGCATGACGCTGGAAGACGAAATCGCCGTCAACAAGGCGCTGCTTGCCTCCGGCGCACCCATTTCGGCCATG
AATGCGGTGCGCAAACACCTGTCCACCATCAAGGGGGGCAGGCTTGCTGCCGCAGCCCACCCGGCAAAGGTGTTTTCGCT
GGTTGTCTCGGATATTCCGGGCGACAATCCCGCTTTCGTGGCCTCTGGCCCAACCGTGCCGGATGAAACCAGCCGCGATG
AGGCCCTGAAGATCATCGAGCGTTATCGGCTGGATTTGCCGCAAGCGGCACTCGCACATATCAAAAGCGAGAATGCGCAC
GCGCCGCAGCCGGACGACGGGGTTTTCGCCCGAAACGAGGTGCGTGTCATCGCCTCGGCTGCCGTTTCGCTGGAAGCGGC
GGCAAGAGAAGCCAGCCGCCACGGCGTTGAAGCCGTCATCCTTTCCGATTCGGTGGAGGGTGAGGCGCGGGAAGTGGCGC
ATGTTCATGCGGCGATTGCCCGCGAAGTGGCGGAGCGTGACCGCCCCTTCAAAAAGCCCGTGGTCATTCTGTCGGGCGGC
GAAACAACCGTCACCATCGGCAGCCCCGGCGGTAAAGGCGGGCGCAACAGCGAATTTCTTCTGTCCTTCGCGCTCGATAT
CGACGGTTATGCCAATATCCACGCGCTTGCCGCCGATACGGATGGCATTGACGGGTCGGAAGATAATGCCGGAGCCTTTG
CCGATGGCGGCACTGTTTCACGGCTGCAAAAGCTTGGCGAGGATGGCATGGCGCGGCTCAACGCCAATGATGCCTGGACG
GCTTTCGATGCGCTTGGCGATCTGTTCGTGCCGGGGCCGACCGGAACCAATGTCAATGATCTCAGAGCTATTTTGATAAC
GGTTTAG

Upstream 100 bases:

>100_bases
ATGAAAGCCGATCTTTTGTAAGAGAAGAAAGCGGGCTTCGTTGATTTTATTCGGGCAGCGCGGAATAGTCCTGCCAGCTA
CACATCATATCGGGAATCTC

Downstream 100 bases:

>100_bases
ACTCATCATCAAGCAGGATGCGGTTGGCCGCTCCATCCAGATCGTCATACTGGCCGCTTTTCAGCGACCAGAGGAATGCG
GCAAGGCCGAGCAGCCCCAG

Product: hydroxypyruvate reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 428; Mature: 427

Protein sequence:

>428_residues
MSAIADPKKFLTSLFDAAVAAADPELVIRANLPEKPKGRTIVIGAGKGSAQMAAAFERAWAEKHDAPLEGVVVTRYGYGA
PCERIRIIEAAHPVPDGAGLAASRRLFNAVSGLSEDDLVVALISGGGSALLPSPPEGMTLEDEIAVNKALLASGAPISAM
NAVRKHLSTIKGGRLAAAAHPAKVFSLVVSDIPGDNPAFVASGPTVPDETSRDEALKIIERYRLDLPQAALAHIKSENAH
APQPDDGVFARNEVRVIASAAVSLEAAAREASRHGVEAVILSDSVEGEAREVAHVHAAIAREVAERDRPFKKPVVILSGG
ETTVTIGSPGGKGGRNSEFLLSFALDIDGYANIHALAADTDGIDGSEDNAGAFADGGTVSRLQKLGEDGMARLNANDAWT
AFDALGDLFVPGPTGTNVNDLRAILITV

Sequences:

>Translated_428_residues
MSAIADPKKFLTSLFDAAVAAADPELVIRANLPEKPKGRTIVIGAGKGSAQMAAAFERAWAEKHDAPLEGVVVTRYGYGA
PCERIRIIEAAHPVPDGAGLAASRRLFNAVSGLSEDDLVVALISGGGSALLPSPPEGMTLEDEIAVNKALLASGAPISAM
NAVRKHLSTIKGGRLAAAAHPAKVFSLVVSDIPGDNPAFVASGPTVPDETSRDEALKIIERYRLDLPQAALAHIKSENAH
APQPDDGVFARNEVRVIASAAVSLEAAAREASRHGVEAVILSDSVEGEAREVAHVHAAIAREVAERDRPFKKPVVILSGG
ETTVTIGSPGGKGGRNSEFLLSFALDIDGYANIHALAADTDGIDGSEDNAGAFADGGTVSRLQKLGEDGMARLNANDAWT
AFDALGDLFVPGPTGTNVNDLRAILITV
>Mature_427_residues
SAIADPKKFLTSLFDAAVAAADPELVIRANLPEKPKGRTIVIGAGKGSAQMAAAFERAWAEKHDAPLEGVVVTRYGYGAP
CERIRIIEAAHPVPDGAGLAASRRLFNAVSGLSEDDLVVALISGGGSALLPSPPEGMTLEDEIAVNKALLASGAPISAMN
AVRKHLSTIKGGRLAAAAHPAKVFSLVVSDIPGDNPAFVASGPTVPDETSRDEALKIIERYRLDLPQAALAHIKSENAHA
PQPDDGVFARNEVRVIASAAVSLEAAAREASRHGVEAVILSDSVEGEAREVAHVHAAIAREVAERDRPFKKPVVILSGGE
TTVTIGSPGGKGGRNSEFLLSFALDIDGYANIHALAADTDGIDGSEDNAGAFADGGTVSRLQKLGEDGMARLNANDAWTA
FDALGDLFVPGPTGTNVNDLRAILITV

Specific function: Degrades an unidentified toxic product from the first step of tartrate degradation [H]

COG id: COG2379

COG function: function code G; Putative glycerate kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI31543063, Length=489, Percent_Identity=30.6748466257669, Blast_Score=172, Evalue=6e-43,
Organism=Caenorhabditis elegans, GI193205461, Length=464, Percent_Identity=28.8793103448276, Blast_Score=142, Evalue=3e-34,
Organism=Drosophila melanogaster, GI19920578, Length=379, Percent_Identity=32.4538258575198, Blast_Score=134, Evalue=8e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007835 [H]

Pfam domain/function: PF05161 MOFRL [H]

EC number: =1.1.1.81 [H]

Molecular weight: Translated: 44333; Mature: 44202

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAIADPKKFLTSLFDAAVAAADPELVIRANLPEKPKGRTIVIGAGKGSAQMAAAFERAW
CCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCEEEEECCCCCHHHHHHHHHHH
AEKHDAPLEGVVVTRYGYGAPCERIRIIEAAHPVPDGAGLAASRRLFNAVSGLSEDDLVV
HHHCCCCCCCEEEEECCCCCCHHHEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCEEE
ALISGGGSALLPSPPEGMTLEDEIAVNKALLASGAPISAMNAVRKHLSTIKGGRLAAAAH
EEEECCCCCCCCCCCCCCEEHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCEEECCC
PAKVFSLVVSDIPGDNPAFVASGPTVPDETSRDEALKIIERYRLDLPQAALAHIKSENAH
HHHHHHHHHHHCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHCCCCCC
APQPDDGVFARNEVRVIASAAVSLEAAAREASRHGVEAVILSDSVEGEAREVAHVHAAIA
CCCCCCCCEECCHHEEEHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHH
REVAERDRPFKKPVVILSGGETTVTIGSPGGKGGRNSEFLLSFALDIDGYANIHALAADT
HHHHHHCCCCCCCEEEEECCCEEEEECCCCCCCCCCCEEEEEEEECCCCCCCEEEEEECC
DGIDGSEDNAGAFADGGTVSRLQKLGEDGMARLNANDAWTAFDALGDLFVPGPTGTNVND
CCCCCCCCCCCCCCCCCHHHHHHHHCCCCCEEECCCCHHHHHHHHCCEEECCCCCCCHHH
LRAILITV
EEEEEEEC
>Mature Secondary Structure 
SAIADPKKFLTSLFDAAVAAADPELVIRANLPEKPKGRTIVIGAGKGSAQMAAAFERAW
CCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCEEEEECCCCCHHHHHHHHHHH
AEKHDAPLEGVVVTRYGYGAPCERIRIIEAAHPVPDGAGLAASRRLFNAVSGLSEDDLVV
HHHCCCCCCCEEEEECCCCCCHHHEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCEEE
ALISGGGSALLPSPPEGMTLEDEIAVNKALLASGAPISAMNAVRKHLSTIKGGRLAAAAH
EEEECCCCCCCCCCCCCCEEHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCEEECCC
PAKVFSLVVSDIPGDNPAFVASGPTVPDETSRDEALKIIERYRLDLPQAALAHIKSENAH
HHHHHHHHHHHCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHCCCCCC
APQPDDGVFARNEVRVIASAAVSLEAAAREASRHGVEAVILSDSVEGEAREVAHVHAAIA
CCCCCCCCEECCHHEEEHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHH
REVAERDRPFKKPVVILSGGETTVTIGSPGGKGGRNSEFLLSFALDIDGYANIHALAADT
HHHHHHCCCCCCCEEEEECCCEEEEECCCCCCCCCCCEEEEEEEECCCCCCCEEEEEECC
DGIDGSEDNAGAFADGGTVSRLQKLGEDGMARLNANDAWTAFDALGDLFVPGPTGTNVND
CCCCCCCCCCCCCCCCCHHHHHHHHCCCCCEEECCCCHHHHHHHHCCEEECCCCCCCHHH
LRAILITV
EEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]