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The map label for this gene is xdhB [H]

Identifier: 225851894

GI number: 225851894

Start: 380564

End: 382909

Strand: Direct

Name: xdhB [H]

Synonym: BMEA_A0387

Alternate gene names: 225851894

Gene position: 380564-382909 (Clockwise)

Preceding gene: 225851893

Following gene: 225851895

Centisome position: 17.9

GC content: 59.93

Gene sequence:

>2346_bases
ATGAACAGGCATTCCGCAACCGATATCAAGACCGCCCGCATCCGGGGCGGTGTCGCCACCGAACAGAAACACGATTCCGC
ACATAAGCACGTCACGGGAACGGCGGTCTATATTGACGATATTCCCGAGCCGGAAGGCACGTTGCATATCGGGGTCGGTT
ATGCGTCCGTCGCGCATGGCCGGATCAAATCCATGGATCTGGAAGCGGTGCGCGCTGCGCCCGGCGTGGTCGATATCCTC
ACCTGCAAGGACGTGCAGGGCGAAAACGATGTTTCGCCATCGGGTATGCATGACGATCCGATCTTTGCGGTGGACAAGGT
TGAGTTTCACGGCCAGCCGATCTTTGCGGTTATCGCGAAAACCCGCGATCAGGCGCGCCGTGCCGCGCGTCTGGCGAAGA
TCGAATATGAGGAAGCGCCGGGCATCTATTCTATCGATATGCTGGACGGTCTGAAAGACCGGCTTGTCACGCCGCCGCTA
ACGCTGGAGCGCGGCAATGCCCGCGCAGCCATCGATGCTGCCCCGCACCGCATCAGGAACCGTATGTATCTGGGCGGTCA
GGACCATTTCTATCTAGAAGGGCAGGTCTCGCTGGCGGTTCCGGGCGAAGATGAGGATGTGACCGTCTATTGCTCCACCC
AAGGCCCGAGCGAGACACAGCATCTGGTGGCGCACGCATTGGGCGTTTCGAGCCATTCCGTCACCGTGGAAGTGCGCCGC
ATGGGCGGCGGTTTCGGTGGCAAGGAAACACAGGCCAACCAGTGGGCGGCCATTGCCGCCAAAAAACACAAGCGCGCCGT
GAAGATCAGGCTCGACCGCGATGAGGACATGACCTCGACTGGCAAGCGGCATGGCTTTGTGATCGATTATGAAGTGGGCT
TCGACGATGACGGCACTATTCTGGGCGTGGATTATCTCTATGCGCTCAATGCCGGCTTTTCAGCGGACCTTTCCGGCCCG
GTCGGTGACCGCGCGCTGTTCCACTGCGACAATGCCTATTTTTATCCGGCGGTTCATGCGCAGTCCGCGCCGCTCTATAC
CAACACGGTTTCCAACACGGCCTTTCGCGGCTTCGGCGGCCCGCAGGGCATGGCGGGGGCAGAGCGTGTGATCGACAAGG
TGGCCTTCGCCCTCGGCAAAGATCCGCTCGAAATTCGCAAGCGCAATTTCTACGACGAAATGGGCAAGGATGGCACGCGC
AACGTCACGCCCTATCACCAGAAGGTCGAGGACTGCATCATCCAGCGCATCGTTGCACAACTGGAGGAAAGCGCCGATTA
CGCAAAGCGCCGTGAAGCCATCCGGGAATTTAACGCAAAAAGCCGCTATGTAAAGCGGGGCATCGCACTGACGCCGGTGA
AATTCGGCATCTCTTTCACCAAGACGGAGTCCAATCAGGCAGGTGCCCTGGTGCATGTCTATGCCGACGGTTCGGTGCAT
ATGAACCATGGTGGCACGGAAATGGGGCAGGGCCTGCACATGAAGGTGGCGCAGGTCGTGGCGGAAGAATTCCAGATCGA
CATCGACCGGGTGAAAATCACCGCGCCGACCACTGCGAAAGTGCCGAACACCGCGCCGACGGCTGCTTCTTCCGGTGCCG
ACCTGAACGGCATGGCGGCGCAGGATGCCGCCCGCCAGATCAAGAAGCGGCTCATTCGTTTTGCCGCGCAGCAATATCAG
GTGCCGGAAGACCAGATCATGTTTCTGCCGAACCGTGTGCGCGTCGGCAATCAGGAAATCAGCTTCAACGATCTGGTAAA
CCAGGCCTATATCGGCCGTGTGCAGCTTTCGGCGGCGGGCCATTACAAGACACCGAAAATCCACTGGGACCGCGCGAAGG
GCCGCGGCCATGCCTTTTATTATTACGCTTATGGCGCGGCCTGTTCCGAGGTTAGTGTTGATACGCTGACCGGCGAATAT
GTGGTGGAGCGCACCGATATTCTGCATGATACCGGGCGCTCCCTGAACCGCGCCATCGATATCGGCCAGATAGAAGGCGG
CTTCGTGCAGGGCATGGGCTGGCTGACGACCGAGGAACTGGTGTGGGACGAGAAGGGGCGGCTTCGCACCCATGCACCAT
CCACCTACAAGATACCGCTGGCCTCCGACCGGCCAAAGATTTTCAACGTCGCGCTGACCGACTGGTCGGAGGCTTATGAG
CCGACCATTCATCGTTCCAAGGCGGTGGGCGAGCCGCCCCTGCCGCTTGGGCTTTCAGTGCTGCATGCGCTTGCCGATGC
TGTCGCCAGTATGGCCGACTATAAGGTCTGCCCGCGCCTTGATGCGCCCGCAACGCCGGAACGTGTGCTGATGACGGTCG
AACGGCTCCGCAAGCAAAATGGCTAG

Upstream 100 bases:

>100_bases
TGTTGCGCGCAACATGCTGCGCCGTTTCTATCTTGAAACGACCGGCAGCGGCGAAACGCTCGGCGCCCTTCGCGGCGAGG
CGGCGTGAACGGAGGCAGAC

Downstream 100 bases:

>100_bases
GACGATGCCGGGTGCGCGCGACGATATCCGGGCTTTTCTCCACCAGCGTCCCGCCCGAAATGGTCTGGATTGCGTGCTGG
TTGAAGTGACAGATGTGAAA

Product: xanthine dehydrogenase molybdopterin binding subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 781; Mature: 781

Protein sequence:

>781_residues
MNRHSATDIKTARIRGGVATEQKHDSAHKHVTGTAVYIDDIPEPEGTLHIGVGYASVAHGRIKSMDLEAVRAAPGVVDIL
TCKDVQGENDVSPSGMHDDPIFAVDKVEFHGQPIFAVIAKTRDQARRAARLAKIEYEEAPGIYSIDMLDGLKDRLVTPPL
TLERGNARAAIDAAPHRIRNRMYLGGQDHFYLEGQVSLAVPGEDEDVTVYCSTQGPSETQHLVAHALGVSSHSVTVEVRR
MGGGFGGKETQANQWAAIAAKKHKRAVKIRLDRDEDMTSTGKRHGFVIDYEVGFDDDGTILGVDYLYALNAGFSADLSGP
VGDRALFHCDNAYFYPAVHAQSAPLYTNTVSNTAFRGFGGPQGMAGAERVIDKVAFALGKDPLEIRKRNFYDEMGKDGTR
NVTPYHQKVEDCIIQRIVAQLEESADYAKRREAIREFNAKSRYVKRGIALTPVKFGISFTKTESNQAGALVHVYADGSVH
MNHGGTEMGQGLHMKVAQVVAEEFQIDIDRVKITAPTTAKVPNTAPTAASSGADLNGMAAQDAARQIKKRLIRFAAQQYQ
VPEDQIMFLPNRVRVGNQEISFNDLVNQAYIGRVQLSAAGHYKTPKIHWDRAKGRGHAFYYYAYGAACSEVSVDTLTGEY
VVERTDILHDTGRSLNRAIDIGQIEGGFVQGMGWLTTEELVWDEKGRLRTHAPSTYKIPLASDRPKIFNVALTDWSEAYE
PTIHRSKAVGEPPLPLGLSVLHALADAVASMADYKVCPRLDAPATPERVLMTVERLRKQNG

Sequences:

>Translated_781_residues
MNRHSATDIKTARIRGGVATEQKHDSAHKHVTGTAVYIDDIPEPEGTLHIGVGYASVAHGRIKSMDLEAVRAAPGVVDIL
TCKDVQGENDVSPSGMHDDPIFAVDKVEFHGQPIFAVIAKTRDQARRAARLAKIEYEEAPGIYSIDMLDGLKDRLVTPPL
TLERGNARAAIDAAPHRIRNRMYLGGQDHFYLEGQVSLAVPGEDEDVTVYCSTQGPSETQHLVAHALGVSSHSVTVEVRR
MGGGFGGKETQANQWAAIAAKKHKRAVKIRLDRDEDMTSTGKRHGFVIDYEVGFDDDGTILGVDYLYALNAGFSADLSGP
VGDRALFHCDNAYFYPAVHAQSAPLYTNTVSNTAFRGFGGPQGMAGAERVIDKVAFALGKDPLEIRKRNFYDEMGKDGTR
NVTPYHQKVEDCIIQRIVAQLEESADYAKRREAIREFNAKSRYVKRGIALTPVKFGISFTKTESNQAGALVHVYADGSVH
MNHGGTEMGQGLHMKVAQVVAEEFQIDIDRVKITAPTTAKVPNTAPTAASSGADLNGMAAQDAARQIKKRLIRFAAQQYQ
VPEDQIMFLPNRVRVGNQEISFNDLVNQAYIGRVQLSAAGHYKTPKIHWDRAKGRGHAFYYYAYGAACSEVSVDTLTGEY
VVERTDILHDTGRSLNRAIDIGQIEGGFVQGMGWLTTEELVWDEKGRLRTHAPSTYKIPLASDRPKIFNVALTDWSEAYE
PTIHRSKAVGEPPLPLGLSVLHALADAVASMADYKVCPRLDAPATPERVLMTVERLRKQNG
>Mature_781_residues
MNRHSATDIKTARIRGGVATEQKHDSAHKHVTGTAVYIDDIPEPEGTLHIGVGYASVAHGRIKSMDLEAVRAAPGVVDIL
TCKDVQGENDVSPSGMHDDPIFAVDKVEFHGQPIFAVIAKTRDQARRAARLAKIEYEEAPGIYSIDMLDGLKDRLVTPPL
TLERGNARAAIDAAPHRIRNRMYLGGQDHFYLEGQVSLAVPGEDEDVTVYCSTQGPSETQHLVAHALGVSSHSVTVEVRR
MGGGFGGKETQANQWAAIAAKKHKRAVKIRLDRDEDMTSTGKRHGFVIDYEVGFDDDGTILGVDYLYALNAGFSADLSGP
VGDRALFHCDNAYFYPAVHAQSAPLYTNTVSNTAFRGFGGPQGMAGAERVIDKVAFALGKDPLEIRKRNFYDEMGKDGTR
NVTPYHQKVEDCIIQRIVAQLEESADYAKRREAIREFNAKSRYVKRGIALTPVKFGISFTKTESNQAGALVHVYADGSVH
MNHGGTEMGQGLHMKVAQVVAEEFQIDIDRVKITAPTTAKVPNTAPTAASSGADLNGMAAQDAARQIKKRLIRFAAQQYQ
VPEDQIMFLPNRVRVGNQEISFNDLVNQAYIGRVQLSAAGHYKTPKIHWDRAKGRGHAFYYYAYGAACSEVSVDTLTGEY
VVERTDILHDTGRSLNRAIDIGQIEGGFVQGMGWLTTEELVWDEKGRLRTHAPSTYKIPLASDRPKIFNVALTDWSEAYE
PTIHRSKAVGEPPLPLGLSVLHALADAVASMADYKVCPRLDAPATPERVLMTVERLRKQNG

Specific function: Presumed to be a dehydrogenase, but possibly an oxidase. Participates in limited purine salvage (requires aspartate) but does not support aerobic growth on purines as the sole carbon source (purine catabolism) [H]

COG id: COG4631

COG function: function code F; Xanthine dehydrogenase, molybdopterin-binding subunit B

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=757, Percent_Identity=42.4042272126816, Blast_Score=563, Evalue=1e-160,
Organism=Homo sapiens, GI71773480, Length=760, Percent_Identity=38.1578947368421, Blast_Score=482, Evalue=1e-136,
Organism=Escherichia coli, GI1789230, Length=783, Percent_Identity=27.7139208173691, Blast_Score=212, Evalue=7e-56,
Organism=Escherichia coli, GI1789246, Length=790, Percent_Identity=25.5696202531646, Blast_Score=187, Evalue=2e-48,
Organism=Escherichia coli, GI1786478, Length=751, Percent_Identity=25.2996005326232, Blast_Score=124, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17540638, Length=768, Percent_Identity=40.234375, Blast_Score=518, Evalue=1e-147,
Organism=Caenorhabditis elegans, GI32566215, Length=727, Percent_Identity=33.2874828060523, Blast_Score=332, Evalue=5e-91,
Organism=Caenorhabditis elegans, GI17539860, Length=731, Percent_Identity=33.9261285909713, Blast_Score=332, Evalue=6e-91,
Organism=Drosophila melanogaster, GI17737937, Length=765, Percent_Identity=39.8692810457516, Blast_Score=527, Evalue=1e-150,
Organism=Drosophila melanogaster, GI24647199, Length=763, Percent_Identity=31.9790301441678, Blast_Score=327, Evalue=2e-89,
Organism=Drosophila melanogaster, GI24647193, Length=778, Percent_Identity=30.8483290488432, Blast_Score=305, Evalue=1e-82,
Organism=Drosophila melanogaster, GI24647201, Length=763, Percent_Identity=30.9305373525557, Blast_Score=302, Evalue=6e-82,
Organism=Drosophila melanogaster, GI24647197, Length=772, Percent_Identity=29.2746113989637, Blast_Score=281, Evalue=2e-75,
Organism=Drosophila melanogaster, GI24647195, Length=772, Percent_Identity=29.2746113989637, Blast_Score=281, Evalue=2e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274 [H]

Pfam domain/function: PF01315 Ald_Xan_dh_C; PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.17.1.4 [H]

Molecular weight: Translated: 85642; Mature: 85642

Theoretical pI: Translated: 7.07; Mature: 7.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRHSATDIKTARIRGGVATEQKHDSAHKHVTGTAVYIDDIPEPEGTLHIGVGYASVAHG
CCCCCCCCCEEEEECCCCCCCCCCCCCCCEEEEEEEEEECCCCCCCEEEEEECHHHHCCC
RIKSMDLEAVRAAPGVVDILTCKDVQGENDVSPSGMHDDPIFAVDKVEFHGQPIFAVIAK
CCCCCCHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCCCEEEEEEEEECCCCEEEEEHH
TRDQARRAARLAKIEYEEAPGIYSIDMLDGLKDRLVTPPLTLERGNARAAIDAAPHRIRN
HHHHHHHHHHHHHEEHHCCCCEEEEHHHHCHHHHCCCCCCEEECCCCCEEEHHCHHHHHC
RMYLGGQDHFYLEGQVSLAVPGEDEDVTVYCSTQGPSETQHLVAHALGVSSHSVTVEVRR
CEEECCCCEEEEEEEEEEEECCCCCCEEEEECCCCCCHHHHHHHHHHCCCCCEEEEEEEE
MGGGFGGKETQANQWAAIAAKKHKRAVKIRLDRDEDMTSTGKRHGFVIDYEVGFDDDGTI
CCCCCCCCCCCCCHHHHHHHHCCCCEEEEEECCCCCCHHCCCCCCEEEEEEECCCCCCCE
LGVDYLYALNAGFSADLSGPVGDRALFHCDNAYFYPAVHAQSAPLYTNTVSNTAFRGFGG
EEEEEEEEECCCCCCCCCCCCCCCEEEEECCEEEEEEECCCCCCEEEECCCCCCCCCCCC
PQGMAGAERVIDKVAFALGKDPLEIRKRNFYDEMGKDGTRNVTPYHQKVEDCIIQRIVAQ
CCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
LEESADYAKRREAIREFNAKSRYVKRGIALTPVKFGISFTKTESNQAGALVHVYADGSVH
HHHHHHHHHHHHHHHHHCHHHHHHHCCCEEEEEEECEEEEECCCCCCCCEEEEEECCEEE
MNHGGTEMGQGLHMKVAQVVAEEFQIDIDRVKITAPTTAKVPNTAPTAASSGADLNGMAA
ECCCCHHHCCCHHHHHHHHHHHHHEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCHH
QDAARQIKKRLIRFAAQQYQVPEDQIMFLPNRVRVGNQEISFNDLVNQAYIGRVQLSAAG
HHHHHHHHHHHHHHHHHHHCCCCHHEEECCCEEEECCCCCCHHHHHHHHHCCEEEEEECC
HYKTPKIHWDRAKGRGHAFYYYAYGAACSEVSVDTLTGEYVVERTDILHDTGRSLNRAID
CCCCCCEEEECCCCCCCEEEEEEECCCCCCCEEECCCCCHHHHHHHHHHHCCHHHHHEEE
IGQIEGGFVQGMGWLTTEELVWDEKGRLRTHAPSTYKIPLASDRPKIFNVALTDWSEAYE
CCCCCCCCEECCCCCCHHHHEECCCCCEEECCCCEEEEECCCCCCCEEEEEECCCHHHHC
PTIHRSKAVGEPPLPLGLSVLHALADAVASMADYKVCPRLDAPATPERVLMTVERLRKQN
CHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCC
G
C
>Mature Secondary Structure
MNRHSATDIKTARIRGGVATEQKHDSAHKHVTGTAVYIDDIPEPEGTLHIGVGYASVAHG
CCCCCCCCCEEEEECCCCCCCCCCCCCCCEEEEEEEEEECCCCCCCEEEEEECHHHHCCC
RIKSMDLEAVRAAPGVVDILTCKDVQGENDVSPSGMHDDPIFAVDKVEFHGQPIFAVIAK
CCCCCCHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCCCEEEEEEEEECCCCEEEEEHH
TRDQARRAARLAKIEYEEAPGIYSIDMLDGLKDRLVTPPLTLERGNARAAIDAAPHRIRN
HHHHHHHHHHHHHEEHHCCCCEEEEHHHHCHHHHCCCCCCEEECCCCCEEEHHCHHHHHC
RMYLGGQDHFYLEGQVSLAVPGEDEDVTVYCSTQGPSETQHLVAHALGVSSHSVTVEVRR
CEEECCCCEEEEEEEEEEEECCCCCCEEEEECCCCCCHHHHHHHHHHCCCCCEEEEEEEE
MGGGFGGKETQANQWAAIAAKKHKRAVKIRLDRDEDMTSTGKRHGFVIDYEVGFDDDGTI
CCCCCCCCCCCCCHHHHHHHHCCCCEEEEEECCCCCCHHCCCCCCEEEEEEECCCCCCCE
LGVDYLYALNAGFSADLSGPVGDRALFHCDNAYFYPAVHAQSAPLYTNTVSNTAFRGFGG
EEEEEEEEECCCCCCCCCCCCCCCEEEEECCEEEEEEECCCCCCEEEECCCCCCCCCCCC
PQGMAGAERVIDKVAFALGKDPLEIRKRNFYDEMGKDGTRNVTPYHQKVEDCIIQRIVAQ
CCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
LEESADYAKRREAIREFNAKSRYVKRGIALTPVKFGISFTKTESNQAGALVHVYADGSVH
HHHHHHHHHHHHHHHHHCHHHHHHHCCCEEEEEEECEEEEECCCCCCCCEEEEEECCEEE
MNHGGTEMGQGLHMKVAQVVAEEFQIDIDRVKITAPTTAKVPNTAPTAASSGADLNGMAA
ECCCCHHHCCCHHHHHHHHHHHHHEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCHH
QDAARQIKKRLIRFAAQQYQVPEDQIMFLPNRVRVGNQEISFNDLVNQAYIGRVQLSAAG
HHHHHHHHHHHHHHHHHHHCCCCHHEEECCCEEEECCCCCCHHHHHHHHHCCEEEEEECC
HYKTPKIHWDRAKGRGHAFYYYAYGAACSEVSVDTLTGEYVVERTDILHDTGRSLNRAID
CCCCCCEEEECCCCCCCEEEEEEECCCCCCCEEECCCCCHHHHHHHHHHHCCHHHHHEEE
IGQIEGGFVQGMGWLTTEELVWDEKGRLRTHAPSTYKIPLASDRPKIFNVALTDWSEAYE
CCCCCCCCEECCCCCCHHHHEECCCCCEEECCCCEEEEECCCCCCCEEEEEECCCHHHHC
PTIHRSKAVGEPPLPLGLSVLHALADAVASMADYKVCPRLDAPATPERVLMTVERLRKQN
CHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCC
G
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]