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The map label for this gene is ureG

Identifier: 225851822

GI number: 225851822

Start: 299720

End: 300346

Strand: Direct

Name: ureG

Synonym: BMEA_A0306

Alternate gene names: 225851822

Gene position: 299720-300346 (Clockwise)

Preceding gene: 225851821

Following gene: 225851824

Centisome position: 14.1

GC content: 57.26

Gene sequence:

>627_bases
ATGACACAGAAAAATGGACCGCTCCGCGTCGGCATCGGTGGGCCTGTCGGCTCCGGCAAGACCACACTGACCGAAAAGCT
TTGCAAGGCGATGCGCGATAAATATTCGGTCGCCGTCATCACCAACGATATTTATACGCAGGAAGACGCGCTTATTCTGG
CGCGCCGTCAAGCCTTGTCGGAAGACCGTATCATCGGGGTGGAAACGGGTGGTTGCCCGCACACGGCCATTCGTGAGGAT
GCTTCGATCAATCTTCAGGCCGTTGTTGAAATGACCCGCCGGTTTCCGGACCTCGATGTGGTGTTCATCGAATCCGGCGG
TGACAATCTGGCCGCGACCTTCTCGCCCGACCTTGCCGACCTGACCCTCTATGTCATCTCGGTCTGCCAGGGTGAGGAAA
TTCCCCGCAAGGGCGGCCCCGGTATCACGCGGTCAGATTTTCTGGTCATCAACAAGAGCGACCTGGCGCCTTATGTCCAT
GTCGATCTGGAGGTGATGGAGGCTGATGCAATGCGGATGCGCGCAAAGCGCCCCTTCGGCTTTACCGACCTGCATCGGGG
CAAGGGCGTGCAGGAAATCATTGATTTCATCGTCGAAAATGGTGGGCTGGAACCACGTTCAAACTGA

Upstream 100 bases:

>100_bases
GCGCGGCTCTCTCCAGCATGGAGGACCTCGGTTCTGCCACCTTCATCGCGGACATAATGGCGATGAAACACGAAACGCAG
CATTCAAGGCTTTTTCGCTC

Downstream 100 bases:

>100_bases
TAGCCAGGCCCCGCTTTGCGGGGCCTGAATGCAATCGCCGTAAATTATGAGAATGGAGCATTTCCAGCAAAAGTGAGAAA
CGGTTTTGCGTTGGAAAATG

Product: urease accessory protein UreG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 208; Mature: 207

Protein sequence:

>208_residues
MTQKNGPLRVGIGGPVGSGKTTLTEKLCKAMRDKYSVAVITNDIYTQEDALILARRQALSEDRIIGVETGGCPHTAIRED
ASINLQAVVEMTRRFPDLDVVFIESGGDNLAATFSPDLADLTLYVISVCQGEEIPRKGGPGITRSDFLVINKSDLAPYVH
VDLEVMEADAMRMRAKRPFGFTDLHRGKGVQEIIDFIVENGGLEPRSN

Sequences:

>Translated_208_residues
MTQKNGPLRVGIGGPVGSGKTTLTEKLCKAMRDKYSVAVITNDIYTQEDALILARRQALSEDRIIGVETGGCPHTAIRED
ASINLQAVVEMTRRFPDLDVVFIESGGDNLAATFSPDLADLTLYVISVCQGEEIPRKGGPGITRSDFLVINKSDLAPYVH
VDLEVMEADAMRMRAKRPFGFTDLHRGKGVQEIIDFIVENGGLEPRSN
>Mature_207_residues
TQKNGPLRVGIGGPVGSGKTTLTEKLCKAMRDKYSVAVITNDIYTQEDALILARRQALSEDRIIGVETGGCPHTAIREDA
SINLQAVVEMTRRFPDLDVVFIESGGDNLAATFSPDLADLTLYVISVCQGEEIPRKGGPGITRSDFLVINKSDLAPYVHV
DLEVMEADAMRMRAKRPFGFTDLHRGKGVQEIIDFIVENGGLEPRSN

Specific function: Disruption of the ure1 gene cluster suggests that it protects brucellae during their passage through the stomach. The major route of infection in human brucellosis is oral

COG id: COG0378

COG function: function code OK; Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ureG family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UREG1_BRUA2 (Q2YPD2)

Other databases:

- EMBL:   AF361941
- EMBL:   AM040264
- RefSeq:   YP_413774.1
- ProteinModelPortal:   Q2YPD2
- SMR:   Q2YPD2
- STRING:   Q2YPD2
- GeneID:   3789051
- GenomeReviews:   AM040264_GR
- KEGG:   bmf:BAB1_0303
- eggNOG:   COG0378
- HOGENOM:   HBG364734
- OMA:   LCKAMRE
- ProtClustDB:   CLSK864148
- BioCyc:   BMEL359391:BAB1_0303-MONOMER
- GO:   GO:0005737
- GO:   GO:0009405
- HAMAP:   MF_01389
- InterPro:   IPR003495
- InterPro:   IPR012202
- InterPro:   IPR004400
- PIRSF:   PIRSF005624
- TIGRFAMs:   TIGR00101

Pfam domain/function: PF02492 cobW

EC number: NA

Molecular weight: Translated: 22705; Mature: 22574

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQKNGPLRVGIGGPVGSGKTTLTEKLCKAMRDKYSVAVITNDIYTQEDALILARRQALS
CCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCEEEEEEECCCCCCCCHHHHHHHHHCC
EDRIIGVETGGCPHTAIREDASINLQAVVEMTRRFPDLDVVFIESGGDNLAATFSPDLAD
CCCEEEEECCCCCCHHHCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCEEEEECCCHHH
LTLYVISVCQGEEIPRKGGPGITRSDFLVINKSDLAPYVHVDLEVMEADAMRMRAKRPFG
HHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCCCEEEEEEEEEHHHHHHHHHCCCCC
FTDLHRGKGVQEIIDFIVENGGLEPRSN
CCHHHCCCCHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
TQKNGPLRVGIGGPVGSGKTTLTEKLCKAMRDKYSVAVITNDIYTQEDALILARRQALS
CCCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCEEEEEEECCCCCCCCHHHHHHHHHCC
EDRIIGVETGGCPHTAIREDASINLQAVVEMTRRFPDLDVVFIESGGDNLAATFSPDLAD
CCCEEEEECCCCCCHHHCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCEEEEECCCHHH
LTLYVISVCQGEEIPRKGGPGITRSDFLVINKSDLAPYVHVDLEVMEADAMRMRAKRPFG
HHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCCCEEEEEEEEEHHHHHHHHHCCCCC
FTDLHRGKGVQEIIDFIVENGGLEPRSN
CCHHHCCCCHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA