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The map label for this gene is ccmB [H]

Identifier: 225851634

GI number: 225851634

Start: 100743

End: 101408

Strand: Direct

Name: ccmB [H]

Synonym: BMEA_A0100

Alternate gene names: 225851634

Gene position: 100743-101408 (Clockwise)

Preceding gene: 225851633

Following gene: 225851635

Centisome position: 4.74

GC content: 62.01

Gene sequence:

>666_bases
ATGCTGGCCCTGTTCCTTCGCGATATGCGCCTTGGTTTGCGCGCTGGCGGCGGCGCGCTGATCGGCATCCTGTTCTTCCT
CGCGGTGATTTCTGTGATGCCCTTCGGCGTCGGGCCTGACCTCAACCTTCTGGCGCGCATCGGCCCGGCCATGCTTTGGA
TCGGCGCGCTTTTGGCGACGCTTCTTGGTCTCGACCGGCTGTTTCAGGCCGATCGCGAGGATGGATCGCTCGACCTTCTT
TTGATCGGCGCGGACCGGCACATGCTGGCCTTCACCGTTTTCGTGAAATGCGCTGCCCATTGGGTGGCAAGCGTGCTGCC
GCTGGTGGTGGCCTCGCCCATGCTCGGCCTCTTCATGAATATGGATGCAACGGCCATTGGTGCCACGGCGCTGACGCTTC
TGGTCGGCACGCCTGCCATTGCCTTCATCGGCGCGGTGGGGGCGGCGCTGGCGGTGGCATTGCCGCGCGGTGGGCTGCTT
GTTTCGGTGATTGTGCTGCCACTCACCATTCCGGTGCTTATTTTCGGCGTCTCTGCCTCCTATGGCGCGACTGATGCCGT
TGCACCGTTCTTTGCGTCTTTTCTGATTCTTGCCGCACTCACCCTGTTTTTTGCGGTTCTGGGTCCGTTGGCGGCCAGTG
CCGCACTGAAAAATTCGGCGGATTGA

Upstream 100 bases:

>100_bases
CCCATATTCCGTTAGGGCTGGACGGCGCCATTTCGACAACGGGTAACGGGCTGGTGCGTTCGCTTGATATGGCCGCTTTT
TCGGTTGAGGATATCGCCTG

Downstream 100 bases:

>100_bases
CGCAGTTGATTGCGGTCAATTGAACGATATCGGGGGTAAAGCTAAATATAGACCATGATGAAAGACGCCGCAAAAACTGC
AAGCTGGCTTGATCTGGCCA

Product: heme exporter protein CcmB

Products: NA

Alternate protein names: Cytochrome c-type biogenesis protein CycW [H]

Number of amino acids: Translated: 221; Mature: 221

Protein sequence:

>221_residues
MLALFLRDMRLGLRAGGGALIGILFFLAVISVMPFGVGPDLNLLARIGPAMLWIGALLATLLGLDRLFQADREDGSLDLL
LIGADRHMLAFTVFVKCAAHWVASVLPLVVASPMLGLFMNMDATAIGATALTLLVGTPAIAFIGAVGAALAVALPRGGLL
VSVIVLPLTIPVLIFGVSASYGATDAVAPFFASFLILAALTLFFAVLGPLAASAALKNSAD

Sequences:

>Translated_221_residues
MLALFLRDMRLGLRAGGGALIGILFFLAVISVMPFGVGPDLNLLARIGPAMLWIGALLATLLGLDRLFQADREDGSLDLL
LIGADRHMLAFTVFVKCAAHWVASVLPLVVASPMLGLFMNMDATAIGATALTLLVGTPAIAFIGAVGAALAVALPRGGLL
VSVIVLPLTIPVLIFGVSASYGATDAVAPFFASFLILAALTLFFAVLGPLAASAALKNSAD
>Mature_221_residues
MLALFLRDMRLGLRAGGGALIGILFFLAVISVMPFGVGPDLNLLARIGPAMLWIGALLATLLGLDRLFQADREDGSLDLL
LIGADRHMLAFTVFVKCAAHWVASVLPLVVASPMLGLFMNMDATAIGATALTLLVGTPAIAFIGAVGAALAVALPRGGLL
VSVIVLPLTIPVLIFGVSASYGATDAVAPFFASFLILAALTLFFAVLGPLAASAALKNSAD

Specific function: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes [H]

COG id: COG2386

COG function: function code O; ABC-type transport system involved in cytochrome c biogenesis, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CcmB/CycW/HelB family [H]

Homologues:

Organism=Escherichia coli, GI1788528, Length=216, Percent_Identity=42.5925925925926, Blast_Score=119, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003544 [H]

Pfam domain/function: PF03379 CcmB [H]

EC number: NA

Molecular weight: Translated: 22655; Mature: 22655

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLALFLRDMRLGLRAGGGALIGILFFLAVISVMPFGVGPDLNLLARIGPAMLWIGALLAT
CHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
LLGLDRLFQADREDGSLDLLLIGADRHMLAFTVFVKCAAHWVASVLPLVVASPMLGLFMN
HHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
MDATAIGATALTLLVGTPAIAFIGAVGAALAVALPRGGLLVSVIVLPLTIPVLIFGVSAS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCC
YGATDAVAPFFASFLILAALTLFFAVLGPLAASAALKNSAD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLALFLRDMRLGLRAGGGALIGILFFLAVISVMPFGVGPDLNLLARIGPAMLWIGALLAT
CHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
LLGLDRLFQADREDGSLDLLLIGADRHMLAFTVFVKCAAHWVASVLPLVVASPMLGLFMN
HHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
MDATAIGATALTLLVGTPAIAFIGAVGAALAVALPRGGLLVSVIVLPLTIPVLIFGVSAS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCC
YGATDAVAPFFASFLILAALTLFFAVLGPLAASAALKNSAD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1850420; 12597275 [H]