Click here to switch to the map view.

The map label for this gene is bhuA [H]

Identifier: 225686931

GI number: 225686931

Start: 1170493

End: 1172478

Strand: Reverse

Name: bhuA [H]

Synonym: BMEA_B1185

Alternate gene names: 225686931

Gene position: 1172478-1170493 (Counterclockwise)

Preceding gene: 225686938

Following gene: 225686930

Centisome position: 98.9

GC content: 54.98

Gene sequence:

>1986_bases
ATGAAGTTCACGAGAATGCTAGTGCTCGCCAGCACATCTCTGCTTGCCACCGTCGCCACATCGCAGGCTCAGGAAGTAAA
GCGTGATACGAAAAAGCAGGGTGAAGTTGTCCTTAAACCCATTACGATCATAAGCCACGGCAAGGACAATATCGAAGCGA
CCGGCGGCACTGTCCTTACTTATAAAGATATTGAAAAGCTGCAACCTGCCAACGTTTCCGAGTTGTTTTCGCGCCAGTCC
TCCATCGCTGTTTCCGGCGGTGGCGGCCCGTCGAAGCGTATTCACGTTCTTGGCATGGAGCAATCCAATCTGGCGGTCAG
TGTGGATGGCGTGCCGCAAACGGCGACAAGCTGGCACCATACGGGTTCCAACGTAATCGATCCTGCGTTTCTCAAGCGCG
TGGAAGTGGAGGCCGGAGCGGCCGCCGCAGATTCCGGCTTTGGCGCGGCCGCTGGTGCGATCCGCTACGAGACCGTTAAT
GCGCTCGATCTGCTGGAGCCGGGCAAAACCTTCGGTGCGCGCATCATAGGTTCCTACGGTACAAATGGCAGGGGTTTTTC
CGGCAGTACCGCCGCCTATGGCCTCAAGGATGGCTTCGACTGGCTGCTGATGCTGCATGGCACGTCGGGCCACAATTATA
AAAACGGCGATGGAACCGAAATACTCGGCACCGAGCCTGCCGCGCGCAATATTCTGGGCAAGGCCGGTTATGAATTCGAC
GGCAACCGCATCGATATTGGCTATGAACGCAGCCGCGACAAGGCCGACCGTCTTATCAAGATGAATATGGGGCTGCCCGG
CGACACCGAATATCCGCTTGAGGTTGCGCGTGATTCCGTGAACATAAAATATACCCGTACCGATGCTACGGACATGTGGG
ATCCGGAGGTGCAGTTCTATTACAATCGCAACGATTATTGGCGCAACGATTATCAGAACAGGACAAACGGCAACATGATC
CTCAAGGAGGATCTGTATGGCGGCAAGTTGCAGAATACTTTCACGATCGACTACGGCAAGATTACCGCCGGTATCGATTT
TGGCAAGCACGACTACAATACGGACAATTACGGTCATAATGACCGCCGCTACCGCAAGTTCAACACCCAGCAGGTCGGTG
CATTCACGCAAGGCCGGTTTGAATTCGATAACGGCTTCAGCCTTTCGACAGGTGCCCGCTATGACTATAGCCGGTTTGCG
GACTGGAACGATGAGGTGTTTTCAGATAGCGGCGCCAGCGTGAACGGCACGCTATCATACAAGTTCAACGAGCATATCGA
GGTTTTTGCCGGTGCTTCACGGACCTGGCTTGGCTACGTCCTCGGTGATTACGGCTATGTCCACGCCCGCAATAATGCTT
TCTATACCGACCCGACCTTCAGCCCCGGAAGGGCGCGCAATTATAAAGCGGGTGTGAATTTCGGCGGTGCAGACTGGAGT
GCCGGCATTACGCTTTTCGACACGCGCATCGCCGGTCTGCCGAATTATGACAGCCAGAAGCTTGGCAACGATCCGGAAGA
ATATCGTTCGCGAGGCTTTACCCTCAATGCGCGCTATATCTGGAACTACACGACCATTGGCGCAACCTTTACCAAGGCCA
AGGTTACGGCGGGCGACGACCCAGTCTTGCCGAACAGCGGCAGCTTCATGCCGATCGGTGATATGGCGACGCTTTTCATC
GACCAGGAAATCCCCGACTACAATATGAAAGTGGGTGCTACGCTGGCCTGGGCGGGTAGAATTTCAGACGAGGCTGCTAC
TGCTGCCAACTTCTACGATCAGCCTGCCTATACGGTTGTCAACGCCTATGCGGAATGGAATCCGCCAGCGGTTAAGAATA
TGACGTTGCGCGTGGGTGTCGAGAACCTGTTCAACGAAAACTATTACGAGAGAACCAGCTTCGCGCCGAGTCAGAACCGT
GGTGGCATCGATGCGGTTTGGGCGCCGGGCCGGACCTTCACTTTCCAGACGGCCTTCAAGTTCTGA

Upstream 100 bases:

>100_bases
CGCATCTGAAGTGCTCTCATAACCATTTCCCCGCCTCTGCATTGTAGCATTTAAAGCAAAGCGGTTCGCTTTGCTTTATG
GAACCATTTAGAATCAAATC

Downstream 100 bases:

>100_bases
CGGTGACGGCCCTGAGGTAAAACCCGTATCCCGGTTTTTTCTAAAGCATGTCTCCCAAAAGTGCGGGAGGCATACACGAA
AACAAAAGCTTAAAGCGTGT

Product: Heme transporter bhuA

Products: NA

Alternate protein names: Brucella heme uptake protein A [H]

Number of amino acids: Translated: 661; Mature: 661

Protein sequence:

>661_residues
MKFTRMLVLASTSLLATVATSQAQEVKRDTKKQGEVVLKPITIISHGKDNIEATGGTVLTYKDIEKLQPANVSELFSRQS
SIAVSGGGGPSKRIHVLGMEQSNLAVSVDGVPQTATSWHHTGSNVIDPAFLKRVEVEAGAAAADSGFGAAAGAIRYETVN
ALDLLEPGKTFGARIIGSYGTNGRGFSGSTAAYGLKDGFDWLLMLHGTSGHNYKNGDGTEILGTEPAARNILGKAGYEFD
GNRIDIGYERSRDKADRLIKMNMGLPGDTEYPLEVARDSVNIKYTRTDATDMWDPEVQFYYNRNDYWRNDYQNRTNGNMI
LKEDLYGGKLQNTFTIDYGKITAGIDFGKHDYNTDNYGHNDRRYRKFNTQQVGAFTQGRFEFDNGFSLSTGARYDYSRFA
DWNDEVFSDSGASVNGTLSYKFNEHIEVFAGASRTWLGYVLGDYGYVHARNNAFYTDPTFSPGRARNYKAGVNFGGADWS
AGITLFDTRIAGLPNYDSQKLGNDPEEYRSRGFTLNARYIWNYTTIGATFTKAKVTAGDDPVLPNSGSFMPIGDMATLFI
DQEIPDYNMKVGATLAWAGRISDEAATAANFYDQPAYTVVNAYAEWNPPAVKNMTLRVGVENLFNENYYERTSFAPSQNR
GGIDAVWAPGRTFTFQTAFKF

Sequences:

>Translated_661_residues
MKFTRMLVLASTSLLATVATSQAQEVKRDTKKQGEVVLKPITIISHGKDNIEATGGTVLTYKDIEKLQPANVSELFSRQS
SIAVSGGGGPSKRIHVLGMEQSNLAVSVDGVPQTATSWHHTGSNVIDPAFLKRVEVEAGAAAADSGFGAAAGAIRYETVN
ALDLLEPGKTFGARIIGSYGTNGRGFSGSTAAYGLKDGFDWLLMLHGTSGHNYKNGDGTEILGTEPAARNILGKAGYEFD
GNRIDIGYERSRDKADRLIKMNMGLPGDTEYPLEVARDSVNIKYTRTDATDMWDPEVQFYYNRNDYWRNDYQNRTNGNMI
LKEDLYGGKLQNTFTIDYGKITAGIDFGKHDYNTDNYGHNDRRYRKFNTQQVGAFTQGRFEFDNGFSLSTGARYDYSRFA
DWNDEVFSDSGASVNGTLSYKFNEHIEVFAGASRTWLGYVLGDYGYVHARNNAFYTDPTFSPGRARNYKAGVNFGGADWS
AGITLFDTRIAGLPNYDSQKLGNDPEEYRSRGFTLNARYIWNYTTIGATFTKAKVTAGDDPVLPNSGSFMPIGDMATLFI
DQEIPDYNMKVGATLAWAGRISDEAATAANFYDQPAYTVVNAYAEWNPPAVKNMTLRVGVENLFNENYYERTSFAPSQNR
GGIDAVWAPGRTFTFQTAFKF
>Mature_661_residues
MKFTRMLVLASTSLLATVATSQAQEVKRDTKKQGEVVLKPITIISHGKDNIEATGGTVLTYKDIEKLQPANVSELFSRQS
SIAVSGGGGPSKRIHVLGMEQSNLAVSVDGVPQTATSWHHTGSNVIDPAFLKRVEVEAGAAAADSGFGAAAGAIRYETVN
ALDLLEPGKTFGARIIGSYGTNGRGFSGSTAAYGLKDGFDWLLMLHGTSGHNYKNGDGTEILGTEPAARNILGKAGYEFD
GNRIDIGYERSRDKADRLIKMNMGLPGDTEYPLEVARDSVNIKYTRTDATDMWDPEVQFYYNRNDYWRNDYQNRTNGNMI
LKEDLYGGKLQNTFTIDYGKITAGIDFGKHDYNTDNYGHNDRRYRKFNTQQVGAFTQGRFEFDNGFSLSTGARYDYSRFA
DWNDEVFSDSGASVNGTLSYKFNEHIEVFAGASRTWLGYVLGDYGYVHARNNAFYTDPTFSPGRARNYKAGVNFGGADWS
AGITLFDTRIAGLPNYDSQKLGNDPEEYRSRGFTLNARYIWNYTTIGATFTKAKVTAGDDPVLPNSGSFMPIGDMATLFI
DQEIPDYNMKVGATLAWAGRISDEAATAANFYDQPAYTVVNAYAEWNPPAVKNMTLRVGVENLFNENYYERTSFAPSQNR
GGIDAVWAPGRTFTFQTAFKF

Specific function: Heme transporter playing an important role in stationary-phase iron acquisition and required for maintenance of chronic infection in mice [H]

COG id: COG1629

COG function: function code P; Outer membrane receptor proteins, mostly Fe transport

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 72933; Mature: 72933

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFTRMLVLASTSLLATVATSQAQEVKRDTKKQGEVVLKPITIISHGKDNIEATGGTVLT
CCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEECCCCCEEECCCEEEE
YKDIEKLQPANVSELFSRQSSIAVSGGGGPSKRIHVLGMEQSNLAVSVDGVPQTATSWHH
EHHHHHCCCCCHHHHHCCCCCEEEECCCCCCCEEEEEEECCCCEEEEECCCCCCCCCCCC
TGSNVIDPAFLKRVEVEAGAAAADSGFGAAAGAIRYETVNALDLLEPGKTFGARIIGSYG
CCCCCCCHHHHHEEEECCCCCCCCCCCCCCCCEEEEEECCHHHHCCCCCCCCEEEEECCC
TNGRGFSGSTAAYGLKDGFDWLLMLHGTSGHNYKNGDGTEILGTEPAARNILGKAGYEFD
CCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCEEECCCHHHHHHHHCCCCEEC
GNRIDIGYERSRDKADRLIKMNMGLPGDTEYPLEVARDSVNIKYTRTDATDMWDPEVQFY
CCEEEECCCCCCCCCCCEEEEECCCCCCCCCCHHHHCCCEEEEEEECCCCCCCCCCEEEE
YNRNDYWRNDYQNRTNGNMILKEDLYGGKLQNTFTIDYGKITAGIDFGKHDYNTDNYGHN
ECCCCCCCCCCCCCCCCCEEEEECCCCCEECCEEEEEECEEEEEEECCCCCCCCCCCCCC
DRRYRKFNTQQVGAFTQGRFEFDNGFSLSTGARYDYSRFADWNDEVFSDSGASVNGTLSY
CCCEEECCCHHCCCEECCEEEECCCEEECCCCCCCHHHCCCCCCHHHCCCCCCCCEEEEE
KFNEHIEVFAGASRTWLGYVLGDYGYVHARNNAFYTDPTFSPGRARNYKAGVNFGGADWS
EECCCEEEEECCCCEEEEEEECCCEEEEECCCEEECCCCCCCCCCCCEECCCCCCCCCCC
AGITLFDTRIAGLPNYDSQKLGNDPEEYRSRGFTLNARYIWNYTTIGATFTKAKVTAGDD
CCEEEEEEEECCCCCCCHHHCCCCHHHHHHCCCEEEEEEEEEEEEECCEEEEEEEECCCC
PVLPNSGSFMPIGDMATLFIDQEIPDYNMKVGATLAWAGRISDEAATAANFYDQPAYTVV
CCCCCCCCEEECCCEEEEEEECCCCCCCEEECEEEEEECCCCCHHHHHHHCCCCCCEEEE
NAYAEWNPPAVKNMTLRVGVENLFNENYYERTSFAPSQNRGGIDAVWAPGRTFTFQTAFK
EEECCCCCCCCCCEEEEEEHHHHHCCCCHHHCCCCCCCCCCCEEEEECCCCEEEEEEEEC
F
C
>Mature Secondary Structure
MKFTRMLVLASTSLLATVATSQAQEVKRDTKKQGEVVLKPITIISHGKDNIEATGGTVLT
CCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEECCCCCEEECCCEEEE
YKDIEKLQPANVSELFSRQSSIAVSGGGGPSKRIHVLGMEQSNLAVSVDGVPQTATSWHH
EHHHHHCCCCCHHHHHCCCCCEEEECCCCCCCEEEEEEECCCCEEEEECCCCCCCCCCCC
TGSNVIDPAFLKRVEVEAGAAAADSGFGAAAGAIRYETVNALDLLEPGKTFGARIIGSYG
CCCCCCCHHHHHEEEECCCCCCCCCCCCCCCCEEEEEECCHHHHCCCCCCCCEEEEECCC
TNGRGFSGSTAAYGLKDGFDWLLMLHGTSGHNYKNGDGTEILGTEPAARNILGKAGYEFD
CCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCEEECCCHHHHHHHHCCCCEEC
GNRIDIGYERSRDKADRLIKMNMGLPGDTEYPLEVARDSVNIKYTRTDATDMWDPEVQFY
CCEEEECCCCCCCCCCCEEEEECCCCCCCCCCHHHHCCCEEEEEEECCCCCCCCCCEEEE
YNRNDYWRNDYQNRTNGNMILKEDLYGGKLQNTFTIDYGKITAGIDFGKHDYNTDNYGHN
ECCCCCCCCCCCCCCCCCEEEEECCCCCEECCEEEEEECEEEEEEECCCCCCCCCCCCCC
DRRYRKFNTQQVGAFTQGRFEFDNGFSLSTGARYDYSRFADWNDEVFSDSGASVNGTLSY
CCCEEECCCHHCCCEECCEEEECCCEEECCCCCCCHHHCCCCCCHHHCCCCCCCCEEEEE
KFNEHIEVFAGASRTWLGYVLGDYGYVHARNNAFYTDPTFSPGRARNYKAGVNFGGADWS
EECCCEEEEECCCCEEEEEEECCCEEEEECCCEEECCCCCCCCCCCCEECCCCCCCCCCC
AGITLFDTRIAGLPNYDSQKLGNDPEEYRSRGFTLNARYIWNYTTIGATFTKAKVTAGDD
CCEEEEEEEECCCCCCCHHHCCCCHHHHHHCCCEEEEEEEEEEEEECCEEEEEEEECCCC
PVLPNSGSFMPIGDMATLFIDQEIPDYNMKVGATLAWAGRISDEAATAANFYDQPAYTVV
CCCCCCCCEEECCCEEEEEEECCCCCCCEEECEEEEEECCCCCHHHHHHHCCCCCCEEEE
NAYAEWNPPAVKNMTLRVGVENLFNENYYERTSFAPSQNRGGIDAVWAPGRTFTFQTAFK
EEECCCCCCCCCCEEEEEEHHHHHCCCCHHHCCCCCCCCCCCEEEEECCCCEEEEEEEEC
F
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA