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The map label for this gene is xylR [H]

Identifier: 225686930

GI number: 225686930

Start: 1169113

End: 1170237

Strand: Reverse

Name: xylR [H]

Synonym: BMEA_B1184

Alternate gene names: 225686930

Gene position: 1170237-1169113 (Counterclockwise)

Preceding gene: 225686931

Following gene: 225686929

Centisome position: 98.71

GC content: 60.18

Gene sequence:

>1125_bases
ATGAGTATACACCTTGGCATGGTGTTGAAAATCCTGCGTGACGAGGGGCCGCAATCGCGGGCCGAGCTGGCGAGGCGTTG
CGGATTGTCGGCCACGACCCTCACGCATCTCACGGCGCAACTGCTCAAAGATGGTTGCATTGCCGAAACCGACGCTCCAG
TTCTGCCTTCGGGATCACCGATGCCGGGCAGGCCTCCAGTCAGTGTGCGTCTGGTTCCCTCGGCTCATTATGTGGCTGGC
GTGCATATTGGCGCCGAAGCTGTGCAGGTGGCGATTTGCGATCTGACGGCGCAACTGGTCACCAGCGCTGCTTTCGATCA
TGCCGCAAACGATAATCCGCTGAAACTGACGCATCAGACAGCCGATGTTCTGCGCAATCTCGTGCAGGCCAAAGGCATTT
CATTGGGTAGCCTCGTCGGTATCGGCATGGGGGTGCCAGGACCGGTCGATCAGGTGCGCCGCCGCAATTTGCTGTCAATC
AATACCGGCTGGCGCGATGTCGCTTTTGCCGATGCAATGGAAGCGGAACTGAATATTCCAACTGTGGTTGAGCATAATGT
TACAGCCATGGCGCTTGCCGAGGCCCATTACGGCATAGGGCAGGGCTGCCCGGCTGTTCTTTATGTCTATCTTGGTACGG
GGCTGGGAGCGGGGCTGGTGGTGGACGGCATGCCGTTTCGCCCCGGCGGTCATGGTGCGGTGGAGCTAGGACATATCCAG
ATCGATCCGCAAGGTGCGCTTTGCGCCTGCGGCAATCGCGGCTGTCTGGAGACCTTTGTGTCGGAACGCGTGTTGCGCGA
GCGTGGCGCTGGCAGCGCAGAGCCGCTTCTTGCGGCGCTCGCCCGTAACCCGGCATTGCATGATGAAGTGGCAGGCCACT
TTACAACTGCGCTCGCCAATGCGGTCAATTTGCTGACACCGGATTTGATCGTGCTCGGGGGGCATTTTGCGGAAGCGCCA
GAAGCTTTCTACGCGCGTTTGCGGTGCGATCTGCCGCCACGGGTGCTGCCGCATATGCGCGATGTCTTGCGGATAGAGCG
CGGCGGTTTCGGGAACAATGCTGACGCAGTGGGCGCGGCTGCCGTCGCACTGGACCACCTGTTTTATTCGGGAGTATCCC
GATGA

Upstream 100 bases:

>100_bases
ACATAAGCCAGTCCAGGTTTTATCCGCAGCCTACACAAACGAAAATTGTTGACAGACCTATTTATTTACTAAACCTTAGA
AAATAAATAGGGGAAGCCGC

Downstream 100 bases:

>100_bases
ATGCACGCCTGACGGGTCTGGGCCTCAATCTTCTTTCCTTTGCCGTGGGGATCGGTGGCTGGTATCTCCTCACGGCCACG
GGGGCGGTGGTGCTGCCCGG

Product: ROK family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 374; Mature: 373

Protein sequence:

>374_residues
MSIHLGMVLKILRDEGPQSRAELARRCGLSATTLTHLTAQLLKDGCIAETDAPVLPSGSPMPGRPPVSVRLVPSAHYVAG
VHIGAEAVQVAICDLTAQLVTSAAFDHAANDNPLKLTHQTADVLRNLVQAKGISLGSLVGIGMGVPGPVDQVRRRNLLSI
NTGWRDVAFADAMEAELNIPTVVEHNVTAMALAEAHYGIGQGCPAVLYVYLGTGLGAGLVVDGMPFRPGGHGAVELGHIQ
IDPQGALCACGNRGCLETFVSERVLRERGAGSAEPLLAALARNPALHDEVAGHFTTALANAVNLLTPDLIVLGGHFAEAP
EAFYARLRCDLPPRVLPHMRDVLRIERGGFGNNADAVGAAAVALDHLFYSGVSR

Sequences:

>Translated_374_residues
MSIHLGMVLKILRDEGPQSRAELARRCGLSATTLTHLTAQLLKDGCIAETDAPVLPSGSPMPGRPPVSVRLVPSAHYVAG
VHIGAEAVQVAICDLTAQLVTSAAFDHAANDNPLKLTHQTADVLRNLVQAKGISLGSLVGIGMGVPGPVDQVRRRNLLSI
NTGWRDVAFADAMEAELNIPTVVEHNVTAMALAEAHYGIGQGCPAVLYVYLGTGLGAGLVVDGMPFRPGGHGAVELGHIQ
IDPQGALCACGNRGCLETFVSERVLRERGAGSAEPLLAALARNPALHDEVAGHFTTALANAVNLLTPDLIVLGGHFAEAP
EAFYARLRCDLPPRVLPHMRDVLRIERGGFGNNADAVGAAAVALDHLFYSGVSR
>Mature_373_residues
SIHLGMVLKILRDEGPQSRAELARRCGLSATTLTHLTAQLLKDGCIAETDAPVLPSGSPMPGRPPVSVRLVPSAHYVAGV
HIGAEAVQVAICDLTAQLVTSAAFDHAANDNPLKLTHQTADVLRNLVQAKGISLGSLVGIGMGVPGPVDQVRRRNLLSIN
TGWRDVAFADAMEAELNIPTVVEHNVTAMALAEAHYGIGQGCPAVLYVYLGTGLGAGLVVDGMPFRPGGHGAVELGHIQI
DPQGALCACGNRGCLETFVSERVLRERGAGSAEPLLAALARNPALHDEVAGHFTTALANAVNLLTPDLIVLGGHFAEAPE
AFYARLRCDLPPRVLPHMRDVLRIERGGFGNNADAVGAAAVALDHLFYSGVSR

Specific function: Transcriptional repressor of xylose-utilizing enzymes [H]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Escherichia coli, GI1787878, Length=380, Percent_Identity=26.0526315789474, Blast_Score=128, Evalue=6e-31,
Organism=Escherichia coli, GI1786891, Length=375, Percent_Identity=26.4, Blast_Score=124, Evalue=8e-30,
Organism=Escherichia coli, GI1790522, Length=237, Percent_Identity=32.4894514767932, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI87081733, Length=257, Percent_Identity=25.6809338521401, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1787363, Length=307, Percent_Identity=25.7328990228013, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: NA

Molecular weight: Translated: 39158; Mature: 39026

Theoretical pI: Translated: 6.56; Mature: 6.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIHLGMVLKILRDEGPQSRAELARRCGLSATTLTHLTAQLLKDGCIAETDAPVLPSGSP
CEEHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
MPGRPPVSVRLVPSAHYVAGVHIGAEAVQVAICDLTAQLVTSAAFDHAANDNPLKLTHQT
CCCCCCEEEEEECCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHH
ADVLRNLVQAKGISLGSLVGIGMGVPGPVDQVRRRNLLSINTGWRDVAFADAMEAELNIP
HHHHHHHHHHCCCCHHHHHHCCCCCCCCHHHHHCCCEEEECCCCCHHHHHHHHHHCCCCC
TVVEHNVTAMALAEAHYGIGQGCPAVLYVYLGTGLGAGLVVDGMPFRPGGHGAVELGHIQ
EEECCCCHHEEHHHHHCCCCCCCHHHHHHHHHCCCCCCEEECCCCCCCCCCCCEEEEEEE
IDPQGALCACGNRGCLETFVSERVLRERGAGSAEPLLAALARNPALHDEVAGHFTTALAN
ECCCCCEEECCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHH
AVNLLTPDLIVLGGHFAEAPEAFYARLRCDLPPRVLPHMRDVLRIERGGFGNNADAVGAA
HHHHCCCCEEEECCCHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHH
AVALDHLFYSGVSR
HHHHHHHHHHCCCC
>Mature Secondary Structure 
SIHLGMVLKILRDEGPQSRAELARRCGLSATTLTHLTAQLLKDGCIAETDAPVLPSGSP
EEHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
MPGRPPVSVRLVPSAHYVAGVHIGAEAVQVAICDLTAQLVTSAAFDHAANDNPLKLTHQT
CCCCCCEEEEEECCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHH
ADVLRNLVQAKGISLGSLVGIGMGVPGPVDQVRRRNLLSINTGWRDVAFADAMEAELNIP
HHHHHHHHHHCCCCHHHHHHCCCCCCCCHHHHHCCCEEEECCCCCHHHHHHHHHHCCCCC
TVVEHNVTAMALAEAHYGIGQGCPAVLYVYLGTGLGAGLVVDGMPFRPGGHGAVELGHIQ
EEECCCCHHEEHHHHHCCCCCCCHHHHHHHHHCCCCCCEEECCCCCCCCCCCCEEEEEEE
IDPQGALCACGNRGCLETFVSERVLRERGAGSAEPLLAALARNPALHDEVAGHFTTALAN
ECCCCCEEECCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHH
AVNLLTPDLIVLGGHFAEAPEAFYARLRCDLPPRVLPHMRDVLRIERGGFGNNADAVGAA
HHHHCCCCEEEECCCHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHH
AVALDHLFYSGVSR
HHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2544559 [H]