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The map label for this gene is znuA [H]

Identifier: 225686869

GI number: 225686869

Start: 1091581

End: 1092585

Strand: Reverse

Name: znuA [H]

Synonym: BMEA_B1116

Alternate gene names: 225686869

Gene position: 1092585-1091581 (Counterclockwise)

Preceding gene: 225686874

Following gene: 225686867

Centisome position: 92.16

GC content: 54.53

Gene sequence:

>1005_bases
ATGAAAAATCTGCATTCCTTGTTTCTTGCTTCTGCCTTTCTGGCTGGCTTTTGCGGTTCTTCCCTTGCAGGCGAACGTGA
GGGCGTGGTTGTTTCGATCAAGCCGCTTCACTCGATTGTTTCCGCCGTCATGCAGGGCGTGGGTAAGCCGAAGCTGATCG
TTCAGGGGGCTGGGTCCGAGCATGTTTATAGTCTGAAACCCTCCGATGCCGAGGCTATCGAGCACGCCAAGGTGATTTTC
TGGGCCGGGCCATCCATGGAAACCTTTTTCGACAAGCCCATTGATACGCTGGGCGAGGGCGCGAAAGTGGTGGCTCTTGG
CGATGCGAAAGGGTTGACGAAACTAAAATTCCGCGAGGGTGGGCCGTTCGAGGCGCACGATCATGGCCATGGGGGGAGCC
ATGAGGAAGAGCATGACGCACATGGTTCAGGCGATCACGACCATGCGGCCGAAGTCGCAGAAGAAGGCCATGAACACCAC
CATCACGGCGAATATGATCTGCATTTCTGGCTTGACCCGCAAAATGGCAAGATTCTGGCTGCCGATATCGCCAAAACGCT
TGGCGAGAGCGACCCGGAACACGCCGCGCAATATGAAAAGAATGCCAAGGCCTATGGAGAAAAACTCGATGCCTTGACCA
GGGAAGTGGCTGCTGAACTGAAGCCGGTCAAGGACAAGCCCTTCATCGTCTTTCATGATGCCTATCAATATTTCGAGAAT
CGCTTCGGCATGAAAGCAGCCGGCTCCATCACGGTCAGCCCGGAAAAAGCGCCGGGTGCGGCGCGTATCCAGCAAATTCA
CGACAAGATAAAGTCACTCGGTGCAACCTGCGTTTTCTCAGAGCCGCAATTTGAGCCGAAACTGGTGAAGACGGTGGTTG
ACGGAACGAAAGCCCGGACAGGTGTTCTTGATCCTCTTGGCGCAGAACTGAAGGACGGCCCTGATCTTTATCCGCAACTC
ATCCGCAATCTGGCCAATTCGCTGAAAGACTGCCTGTCGAAATAA

Upstream 100 bases:

>100_bases
CTCATCTTATGGCAGACGTTATAGCATAACGCAATTGGCGTAATAAAATAACATATCATGCAAATATGATGTTCCTCCCC
GATTGCTCAAGAGAGATACC

Downstream 100 bases:

>100_bases
ATCAGGCGCTCTTGCTCCCTTTCCGTGGCAGGCAACGGGAAGCGGCTGCAAGGGGGCTGGGCCGTCTTGCCGGTAAAGGT
GAGGCGGCCTGTCCCTCGCA

Product: zinc uptake ABC transporter substrate-binding protein

Products: Zn (II) [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MKNLHSLFLASAFLAGFCGSSLAGEREGVVVSIKPLHSIVSAVMQGVGKPKLIVQGAGSEHVYSLKPSDAEAIEHAKVIF
WAGPSMETFFDKPIDTLGEGAKVVALGDAKGLTKLKFREGGPFEAHDHGHGGSHEEEHDAHGSGDHDHAAEVAEEGHEHH
HHGEYDLHFWLDPQNGKILAADIAKTLGESDPEHAAQYEKNAKAYGEKLDALTREVAAELKPVKDKPFIVFHDAYQYFEN
RFGMKAAGSITVSPEKAPGAARIQQIHDKIKSLGATCVFSEPQFEPKLVKTVVDGTKARTGVLDPLGAELKDGPDLYPQL
IRNLANSLKDCLSK

Sequences:

>Translated_334_residues
MKNLHSLFLASAFLAGFCGSSLAGEREGVVVSIKPLHSIVSAVMQGVGKPKLIVQGAGSEHVYSLKPSDAEAIEHAKVIF
WAGPSMETFFDKPIDTLGEGAKVVALGDAKGLTKLKFREGGPFEAHDHGHGGSHEEEHDAHGSGDHDHAAEVAEEGHEHH
HHGEYDLHFWLDPQNGKILAADIAKTLGESDPEHAAQYEKNAKAYGEKLDALTREVAAELKPVKDKPFIVFHDAYQYFEN
RFGMKAAGSITVSPEKAPGAARIQQIHDKIKSLGATCVFSEPQFEPKLVKTVVDGTKARTGVLDPLGAELKDGPDLYPQL
IRNLANSLKDCLSK
>Mature_334_residues
MKNLHSLFLASAFLAGFCGSSLAGEREGVVVSIKPLHSIVSAVMQGVGKPKLIVQGAGSEHVYSLKPSDAEAIEHAKVIF
WAGPSMETFFDKPIDTLGEGAKVVALGDAKGLTKLKFREGGPFEAHDHGHGGSHEEEHDAHGSGDHDHAAEVAEEGHEHH
HHGEYDLHFWLDPQNGKILAADIAKTLGESDPEHAAQYEKNAKAYGEKLDALTREVAAELKPVKDKPFIVFHDAYQYFEN
RFGMKAAGSITVSPEKAPGAARIQQIHDKIKSLGATCVFSEPQFEPKLVKTVVDGTKARTGVLDPLGAELKDGPDLYPQL
IRNLANSLKDCLSK

Specific function: Involved in the high-affinity zinc uptake transport system. Required for survival and normal growth under low Zn (2+) concentrations. Also required for virulence and intracellular growth in macrophages [H]

COG id: COG4531

COG function: function code P; ABC-type Zn2+ transport system, periplasmic component/surface adhesin

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 9 family [H]

Homologues:

Organism=Escherichia coli, GI87081990, Length=305, Percent_Identity=37.0491803278689, Blast_Score=210, Evalue=1e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006127 [H]

Pfam domain/function: PF01297 SBP_bac_9 [H]

EC number: NA

Molecular weight: Translated: 36070; Mature: 36070

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNLHSLFLASAFLAGFCGSSLAGEREGVVVSIKPLHSIVSAVMQGVGKPKLIVQGAGSE
CCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEHHHHHHHHHHHHCCCCCEEEEECCCCC
HVYSLKPSDAEAIEHAKVIFWAGPSMETFFDKPIDTLGEGAKVVALGDAKGLTKLKFREG
CEEEECCCCHHHHCCEEEEEEECCCHHHHHCCCHHHHCCCCEEEEECCCCCCEEEEECCC
GPFEAHDHGHGGSHEEEHDAHGSGDHDHAAEVAEEGHEHHHHGEYDLHFWLDPQNGKILA
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCEEH
ADIAKTLGESDPEHAAQYEKNAKAYGEKLDALTREVAAELKPVKDKPFIVFHDAYQYFEN
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHH
RFGMKAAGSITVSPEKAPGAARIQQIHDKIKSLGATCVFSEPQFEPKLVKTVVDGTKART
HCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHCCCCCCC
GVLDPLGAELKDGPDLYPQLIRNLANSLKDCLSK
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKNLHSLFLASAFLAGFCGSSLAGEREGVVVSIKPLHSIVSAVMQGVGKPKLIVQGAGSE
CCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEHHHHHHHHHHHHCCCCCEEEEECCCCC
HVYSLKPSDAEAIEHAKVIFWAGPSMETFFDKPIDTLGEGAKVVALGDAKGLTKLKFREG
CEEEECCCCHHHHCCEEEEEEECCCHHHHHCCCHHHHCCCCEEEEECCCCCCEEEEECCC
GPFEAHDHGHGGSHEEEHDAHGSGDHDHAAEVAEEGHEHHHHGEYDLHFWLDPQNGKILA
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCEEH
ADIAKTLGESDPEHAAQYEKNAKAYGEKLDALTREVAAELKPVKDKPFIVFHDAYQYFEN
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHH
RFGMKAAGSITVSPEKAPGAARIQQIHDKIKSLGATCVFSEPQFEPKLVKTVVDGTKART
HCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHCCCCCCC
GVLDPLGAELKDGPDLYPQLIRNLANSLKDCLSK
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Zn (II) [Periplasm]; H2O; ATP [C]

Specific reaction: Zn (II) [Periplasm] + H2O + ATP = Zn (II) [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA