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The map label for this gene is yciC [H]

Identifier: 225686867

GI number: 225686867

Start: 1090212

End: 1091414

Strand: Reverse

Name: yciC [H]

Synonym: BMEA_B1114

Alternate gene names: 225686867

Gene position: 1091414-1090212 (Counterclockwise)

Preceding gene: 225686869

Following gene: 225686861

Centisome position: 92.06

GC content: 56.28

Gene sequence:

>1203_bases
ATGCAAAAGCGGCTTCCCGTTACGGTTTTGTCCGGCTTTCTCGGGGCAGGCAAGACGACACTGCTCAATCATGTGCTCAA
CAATCGGGAAAACCGCCGTGTGGCGGTGATCGTCAACGATATGAGCGAGATCAATGTTGACGCTGCCCTTATCCGCGAGG
GCGGGGCTGATCTTTCCCGCACCGAGGAGCAGCTTGTCGAAATGACCAATGGCTGCATTTGCTGCACGCTGCGCGATGAT
CTTTTGAAAGAGGTCTCGCAACTGGCCGCTCAGGGACGCTTCGATTATCTCCTGATCGAATCGACCGGAATTTCGGAACC
CTTGCCGGTGGCGGCCACTTTCGAGTTTCGCGATGAGAGAGGCAAAAGCCTTTCCGATGGCGCCCGGCTGGACACGATGG
TTACAGTGGTGGACGCAGCCAATTTTCTCAAAGACTACGCTTCAGGTGATTTTCTGCGTGATCGCGGCGAGTCGCTCGGT
GAAGAAGACGAGCGTACGCTTGTCGATCTTCTGGTCGAGCAGATCGAGTTTGCCAATGTCGTGGTGTTGAACAAGATATC
CATGGTGTCGAAAGAGGAATGTGCGCTGGCGCGCAAGGTTATCCGCTCGCTCAACCCGGACGCCCGCATCGAGGAGACGG
ATTTTGGGCAGGTGCCGCTCAATACGATTCTCGACACGCGCCTGTTCGATTTCAACAAGGCGCATGAACATCCGCTCTGG
TACAAGGAGCTTTATGGTTTCAACCAGCATGTGCCGGAAACCGAGGAATATGGTGCCCGCTCCTTTGTCTATAGGGCGCG
AAAACCCTTCGATCCGGCGCGGTTTCAAGCCTTCATCGACCAGAACTGGCCCGGTGTCGTGCGCTCAAAAGGCTTTTTCT
GGTTGGCGACCCGGCCCGATTTCGTGGGTGAGATCAGCCAGGCAGGTGCTTTGGTGCGCACAAGCAAACGAGGACGCTGG
TGGTCCGCCGTGCCGAAGCACTATTGGCCTGCCGAACCCGAATGGCAGCGCGCCATGCAGCCCTATTTTCATGAGGTCTG
GGGCGACCGGCGGCAGGAAATTGTTTTTATCGGCATCGATCCGATGCGGCAGGAAGCGATTATCGCAGAACTTGATAAAT
GTCTGGTGCAGGAGGAATGCTTCGCACCAGAGTGCTGGTCAGGCTTGAGCGATCCATTTCCGAACTGGTCGGAAGCGGCA
TAG

Upstream 100 bases:

>100_bases
TTGCCGGTAAAGGTGAGGCGGCCTGTCCCTCGCAGGCTGCCTCACGACACTTGCCTTCAATCTCGACCACCATCACGACT
GATTTTAAAGGAGCGGCGCC

Downstream 100 bases:

>100_bases
AGCGGTTCCTGTTTTAACAGACACGCGGGAACCGCTTCATTCAGATCGAAACGCACTGAACTATTGAGCGAGCAATGCGA
TATCCAGCGCCTTGCTGTCG

Product: cobalamin synthesis protein/P47K family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 400; Mature: 400

Protein sequence:

>400_residues
MQKRLPVTVLSGFLGAGKTTLLNHVLNNRENRRVAVIVNDMSEINVDAALIREGGADLSRTEEQLVEMTNGCICCTLRDD
LLKEVSQLAAQGRFDYLLIESTGISEPLPVAATFEFRDERGKSLSDGARLDTMVTVVDAANFLKDYASGDFLRDRGESLG
EEDERTLVDLLVEQIEFANVVVLNKISMVSKEECALARKVIRSLNPDARIEETDFGQVPLNTILDTRLFDFNKAHEHPLW
YKELYGFNQHVPETEEYGARSFVYRARKPFDPARFQAFIDQNWPGVVRSKGFFWLATRPDFVGEISQAGALVRTSKRGRW
WSAVPKHYWPAEPEWQRAMQPYFHEVWGDRRQEIVFIGIDPMRQEAIIAELDKCLVQEECFAPECWSGLSDPFPNWSEAA

Sequences:

>Translated_400_residues
MQKRLPVTVLSGFLGAGKTTLLNHVLNNRENRRVAVIVNDMSEINVDAALIREGGADLSRTEEQLVEMTNGCICCTLRDD
LLKEVSQLAAQGRFDYLLIESTGISEPLPVAATFEFRDERGKSLSDGARLDTMVTVVDAANFLKDYASGDFLRDRGESLG
EEDERTLVDLLVEQIEFANVVVLNKISMVSKEECALARKVIRSLNPDARIEETDFGQVPLNTILDTRLFDFNKAHEHPLW
YKELYGFNQHVPETEEYGARSFVYRARKPFDPARFQAFIDQNWPGVVRSKGFFWLATRPDFVGEISQAGALVRTSKRGRW
WSAVPKHYWPAEPEWQRAMQPYFHEVWGDRRQEIVFIGIDPMRQEAIIAELDKCLVQEECFAPECWSGLSDPFPNWSEAA
>Mature_400_residues
MQKRLPVTVLSGFLGAGKTTLLNHVLNNRENRRVAVIVNDMSEINVDAALIREGGADLSRTEEQLVEMTNGCICCTLRDD
LLKEVSQLAAQGRFDYLLIESTGISEPLPVAATFEFRDERGKSLSDGARLDTMVTVVDAANFLKDYASGDFLRDRGESLG
EEDERTLVDLLVEQIEFANVVVLNKISMVSKEECALARKVIRSLNPDARIEETDFGQVPLNTILDTRLFDFNKAHEHPLW
YKELYGFNQHVPETEEYGARSFVYRARKPFDPARFQAFIDQNWPGVVRSKGFFWLATRPDFVGEISQAGALVRTSKRGRW
WSAVPKHYWPAEPEWQRAMQPYFHEVWGDRRQEIVFIGIDPMRQEAIIAELDKCLVQEECFAPECWSGLSDPFPNWSEAA

Specific function: May bind GTP. Might act as metal chaperone (Potential). Contributes to optimal growth under starvation for zinc [H]

COG id: COG0523

COG function: function code R; Putative GTPases (G3E family)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cobW C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI33469141, Length=262, Percent_Identity=33.969465648855, Blast_Score=142, Evalue=4e-34,
Organism=Homo sapiens, GI126722884, Length=262, Percent_Identity=33.969465648855, Blast_Score=141, Evalue=9e-34,
Organism=Homo sapiens, GI148727351, Length=262, Percent_Identity=33.587786259542, Blast_Score=139, Evalue=6e-33,
Organism=Homo sapiens, GI146231952, Length=262, Percent_Identity=33.206106870229, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI223941779, Length=212, Percent_Identity=34.9056603773585, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI223941776, Length=251, Percent_Identity=33.4661354581673, Blast_Score=125, Evalue=6e-29,
Organism=Homo sapiens, GI119120938, Length=143, Percent_Identity=37.7622377622378, Blast_Score=103, Evalue=3e-22,
Organism=Escherichia coli, GI87082430, Length=368, Percent_Identity=25, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1788499, Length=102, Percent_Identity=37.2549019607843, Blast_Score=71, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6324356, Length=239, Percent_Identity=29.7071129707113, Blast_Score=110, Evalue=3e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003495
- InterPro:   IPR011629 [H]

Pfam domain/function: PF02492 cobW; PF07683 CobW_C [H]

EC number: NA

Molecular weight: Translated: 45573; Mature: 45573

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKRLPVTVLSGFLGAGKTTLLNHVLNNRENRRVAVIVNDMSEINVDAALIREGGADLSR
CCCCCCHHHHHHHHCCCHHHHHHHHHCCCCCCEEEEEEECHHHHCCHHHHHHCCCCCHHH
TEEQLVEMTNGCICCTLRDDLLKEVSQLAAQGRFDYLLIESTGISEPLPVAATFEFRDER
HHHHHHHHHCCEEEEEEHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCEEEEEEEHHHC
GKSLSDGARLDTMVTVVDAANFLKDYASGDFLRDRGESLGEEDERTLVDLLVEQIEFANV
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCE
VVLNKISMVSKEECALARKVIRSLNPDARIEETDFGQVPLNTILDTRLFDFNKAHEHPLW
EEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCH
YKELYGFNQHVPETEEYGARSFVYRARKPFDPARFQAFIDQNWPGVVRSKGFFWLATRPD
HHHHCCCCCCCCCHHHHCCHHHHHHHCCCCCHHHHHHHHCCCCCCCEECCCEEEEECCCH
FVGEISQAGALVRTSKRGRWWSAVPKHYWPAEPEWQRAMQPYFHEVWGDRRQEIVFIGID
HHHHHHHCCCEEEECCCCCCHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECC
PMRQEAIIAELDKCLVQEECFAPECWSGLSDPFPNWSEAA
CHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MQKRLPVTVLSGFLGAGKTTLLNHVLNNRENRRVAVIVNDMSEINVDAALIREGGADLSR
CCCCCCHHHHHHHHCCCHHHHHHHHHCCCCCCEEEEEEECHHHHCCHHHHHHCCCCCHHH
TEEQLVEMTNGCICCTLRDDLLKEVSQLAAQGRFDYLLIESTGISEPLPVAATFEFRDER
HHHHHHHHHCCEEEEEEHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCEEEEEEEHHHC
GKSLSDGARLDTMVTVVDAANFLKDYASGDFLRDRGESLGEEDERTLVDLLVEQIEFANV
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCE
VVLNKISMVSKEECALARKVIRSLNPDARIEETDFGQVPLNTILDTRLFDFNKAHEHPLW
EEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCH
YKELYGFNQHVPETEEYGARSFVYRARKPFDPARFQAFIDQNWPGVVRSKGFFWLATRPD
HHHHCCCCCCCCCHHHHCCHHHHHHHCCCCCHHHHHHHHCCCCCCCEECCCEEEEECCCH
FVGEISQAGALVRTSKRGRWWSAVPKHYWPAEPEWQRAMQPYFHEVWGDRRQEIVFIGID
HHHHHHHCCCEEEECCCCCCHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECC
PMRQEAIIAELDKCLVQEECFAPECWSGLSDPFPNWSEAA
CHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377; 9811636 [H]