| Definition | Brucella melitensis ATCC 23457 chromosome chromosome II, complete sequence. |
|---|---|
| Accession | NC_012442 |
| Length | 1,185,518 |
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The map label for this gene is appD [H]
Identifier: 225686839
GI number: 225686839
Start: 1050007
End: 1050999
Strand: Reverse
Name: appD [H]
Synonym: BMEA_B1077
Alternate gene names: 225686839
Gene position: 1050999-1050007 (Counterclockwise)
Preceding gene: 225686840
Following gene: 225686838
Centisome position: 88.65
GC content: 56.7
Gene sequence:
>993_bases ATGCTGGAAGTTACCAATCTTTCCATCAGTTTTCCTCACACATCTGGCCGGTTACGCGCCGTCGAAAATATCGACTTCAG TATCGAGAAGGGGAAAGTTCTCACTCTGATCGGTGAATCCGGGTCAGGCAAAACATTGACCGGCCTGTCATTGATGGGAC TTCTGCCGGGTGGTGCGCAGGTGACCGGAAGAATTGCGCTCGAAGGACGCGAGATTTCTGGCCTCAGTGAAGAAAAACTT CGCCACATTCGCGGGCGCGATATTGCCATGGTGTATCAAAACCCGCTTAGTGCGCTCAACCCCGTCTGGCCGGTCGGCGA GCAGATCGCCGAAGCTGTTCTGGCGCATGGGCTGGCCACACGTCACGAGGCCGGGCAACGGGCAATTGCCCTGCTAGGGC GGGTTGGCATACCGGGGCCGGAGCGGGTTTCGAAGCTGTACCCTTTTGAAATATCGGGAGGCATGCGTCAACGCGTGGTC ATCGCTATGGCTCTGGCATGCAATCCCCGGCTTATTATTGCCGACGAACCAACAACGGCACTGGACGTAACGATCAAGGC CCAGATTCTTGACCTGTTGGCTGATCTAGTTGCTCAGGAACAGATCTCGGTGCTCCTCATTACCCATGACATGCATGTAG TTGCCCGACTTGCCGACGATATCCTGGTTCTTTACGCAGGCCGCATGGCTGAACGTGGCCACGTCCGCGATCTACTGGAT CATCCGGCTCATCCCTACACTGCCGGCTTGCTGCGTTCAGCAGACATCCGCTCCCGTCCTCCCCAGACAGATCTCGAAAT ATTGACAGGCCAGCCTCCACGGATCGGGAATTTTCCGACCGGCTGCCGCTTTCACCCGCGTTGCCCATCCTCGGGCGCCC TGTGTCCGACCCATTCACCGGATTTCATCCAACTTTTCTCGTCGGGACAGGCCACCGCTTGTCATTACCCAGCAATCTCT GCGGACAGATTGCAACAGGAGCAGCTTTTATGA
Upstream 100 bases:
>100_bases CTGCATGGTGGTATCTCGTGTTTCCCGGCACCGCGATCATGCTGTGTGCGGCCGCCTCCTCAATTCTCGGCGACAGCCTG ACCGCGCGCAGGAGCAAATG
Downstream 100 bases:
>100_bases CAGTCTCGCTATTACAGGTTCAGGACCTGGTCAAAAGCTTTCCCTCTCGCCACGGGACGCATCCCGTGCGTGCTGTTGAC GGTGTATCGTTCACTCTTTC
Product: ABC transporter
Products: ADP; phosphate; oligopeptides [Cytoplasm] [C]
Alternate protein names: NA
Number of amino acids: Translated: 330; Mature: 330
Protein sequence:
>330_residues MLEVTNLSISFPHTSGRLRAVENIDFSIEKGKVLTLIGESGSGKTLTGLSLMGLLPGGAQVTGRIALEGREISGLSEEKL RHIRGRDIAMVYQNPLSALNPVWPVGEQIAEAVLAHGLATRHEAGQRAIALLGRVGIPGPERVSKLYPFEISGGMRQRVV IAMALACNPRLIIADEPTTALDVTIKAQILDLLADLVAQEQISVLLITHDMHVVARLADDILVLYAGRMAERGHVRDLLD HPAHPYTAGLLRSADIRSRPPQTDLEILTGQPPRIGNFPTGCRFHPRCPSSGALCPTHSPDFIQLFSSGQATACHYPAIS ADRLQQEQLL
Sequences:
>Translated_330_residues MLEVTNLSISFPHTSGRLRAVENIDFSIEKGKVLTLIGESGSGKTLTGLSLMGLLPGGAQVTGRIALEGREISGLSEEKL RHIRGRDIAMVYQNPLSALNPVWPVGEQIAEAVLAHGLATRHEAGQRAIALLGRVGIPGPERVSKLYPFEISGGMRQRVV IAMALACNPRLIIADEPTTALDVTIKAQILDLLADLVAQEQISVLLITHDMHVVARLADDILVLYAGRMAERGHVRDLLD HPAHPYTAGLLRSADIRSRPPQTDLEILTGQPPRIGNFPTGCRFHPRCPSSGALCPTHSPDFIQLFSSGQATACHYPAIS ADRLQQEQLL >Mature_330_residues MLEVTNLSISFPHTSGRLRAVENIDFSIEKGKVLTLIGESGSGKTLTGLSLMGLLPGGAQVTGRIALEGREISGLSEEKL RHIRGRDIAMVYQNPLSALNPVWPVGEQIAEAVLAHGLATRHEAGQRAIALLGRVGIPGPERVSKLYPFEISGGMRQRVV IAMALACNPRLIIADEPTTALDVTIKAQILDLLADLVAQEQISVLLITHDMHVVARLADDILVLYAGRMAERGHVRDLLD HPAHPYTAGLLRSADIRSRPPQTDLEILTGQPPRIGNFPTGCRFHPRCPSSGALCPTHSPDFIQLFSSGQATACHYPAIS ADRLQQEQLL
Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin
COG id: COG0444
COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component
Gene ontology:
Cell location: Cell membrane; Peripheral membrane protein [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 ABC transporter domain [H]
Homologues:
Organism=Homo sapiens, GI42490749, Length=248, Percent_Identity=29.8387096774194, Blast_Score=74, Evalue=2e-13, Organism=Homo sapiens, GI171184400, Length=258, Percent_Identity=29.4573643410853, Blast_Score=72, Evalue=8e-13, Organism=Homo sapiens, GI9955968, Length=254, Percent_Identity=30.3149606299213, Blast_Score=71, Evalue=2e-12, Organism=Homo sapiens, GI9955966, Length=254, Percent_Identity=29.9212598425197, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI45243524, Length=254, Percent_Identity=29.9212598425197, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI116734710, Length=228, Percent_Identity=26.3157894736842, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI21536376, Length=211, Percent_Identity=27.4881516587678, Blast_Score=69, Evalue=9e-12, Organism=Homo sapiens, GI9665248, Length=251, Percent_Identity=29.0836653386454, Blast_Score=66, Evalue=4e-11, Organism=Homo sapiens, GI11967969, Length=236, Percent_Identity=27.5423728813559, Blast_Score=66, Evalue=6e-11, Organism=Escherichia coli, GI48994883, Length=317, Percent_Identity=42.5867507886435, Blast_Score=276, Evalue=1e-75, Organism=Escherichia coli, GI1789963, Length=324, Percent_Identity=41.6666666666667, Blast_Score=264, Evalue=6e-72, Organism=Escherichia coli, GI1787759, Length=319, Percent_Identity=42.6332288401254, Blast_Score=259, Evalue=2e-70, Organism=Escherichia coli, GI145693107, Length=258, Percent_Identity=48.4496124031008, Blast_Score=237, Evalue=8e-64, Organism=Escherichia coli, GI1787548, Length=325, Percent_Identity=34.7692307692308, Blast_Score=194, Evalue=6e-51, Organism=Escherichia coli, GI1788506, Length=255, Percent_Identity=41.1764705882353, Blast_Score=192, Evalue=3e-50, Organism=Escherichia coli, GI1787500, Length=316, Percent_Identity=36.0759493670886, Blast_Score=191, Evalue=5e-50, Organism=Escherichia coli, GI1789962, Length=322, Percent_Identity=34.1614906832298, Blast_Score=183, Evalue=2e-47, Organism=Escherichia coli, GI1789890, Length=234, Percent_Identity=43.1623931623932, Blast_Score=175, Evalue=4e-45, Organism=Escherichia coli, GI1787758, Length=303, Percent_Identity=33.993399339934, Blast_Score=162, Evalue=2e-41, Organism=Escherichia coli, GI48994997, Length=255, Percent_Identity=37.2549019607843, Blast_Score=138, Evalue=6e-34, Organism=Escherichia coli, GI1789032, Length=256, Percent_Identity=33.203125, Blast_Score=125, Evalue=3e-30, Organism=Escherichia coli, GI1786398, Length=256, Percent_Identity=32.8125, Blast_Score=123, Evalue=2e-29, Organism=Escherichia coli, GI1787547, Length=258, Percent_Identity=31.0077519379845, Blast_Score=116, Evalue=2e-27, Organism=Escherichia coli, GI1788225, Length=255, Percent_Identity=34.9019607843137, Blast_Score=116, Evalue=2e-27, Organism=Escherichia coli, GI1787029, Length=243, Percent_Identity=32.9218106995885, Blast_Score=108, Evalue=5e-25, Organism=Escherichia coli, GI87081709, Length=256, Percent_Identity=30.859375, Blast_Score=108, Evalue=5e-25, Organism=Escherichia coli, GI1787712, Length=255, Percent_Identity=29.8039215686275, Blast_Score=105, Evalue=5e-24, Organism=Escherichia coli, GI87081834, Length=218, Percent_Identity=33.0275229357798, Blast_Score=105, Evalue=5e-24, Organism=Escherichia coli, GI1789891, Length=237, Percent_Identity=31.6455696202532, Blast_Score=103, Evalue=1e-23, Organism=Escherichia coli, GI87081791, Length=257, Percent_Identity=29.1828793774319, Blast_Score=101, Evalue=7e-23, Organism=Escherichia coli, GI1786563, Length=238, Percent_Identity=34.8739495798319, Blast_Score=100, Evalue=1e-22, Organism=Escherichia coli, GI1789672, Length=238, Percent_Identity=31.0924369747899, Blast_Score=97, Evalue=1e-21, Organism=Escherichia coli, GI1790162, Length=250, Percent_Identity=28.8, Blast_Score=96, Evalue=3e-21, Organism=Escherichia coli, GI1787370, Length=233, Percent_Identity=30.9012875536481, Blast_Score=95, Evalue=7e-21, Organism=Escherichia coli, GI1786703, Length=231, Percent_Identity=30.7359307359307, Blast_Score=93, Evalue=2e-20, Organism=Escherichia coli, GI1788761, Length=231, Percent_Identity=28.1385281385281, Blast_Score=91, Evalue=9e-20, Organism=Escherichia coli, GI1788450, Length=242, Percent_Identity=29.7520661157025, Blast_Score=91, Evalue=1e-19, Organism=Escherichia coli, GI1787089, Length=223, Percent_Identity=31.8385650224215, Blast_Score=90, Evalue=2e-19, Organism=Escherichia coli, GI1789991, Length=251, Percent_Identity=28.2868525896414, Blast_Score=90, Evalue=3e-19, Organism=Escherichia coli, GI1788644, Length=181, Percent_Identity=32.5966850828729, Blast_Score=89, Evalue=4e-19, Organism=Escherichia coli, GI1787105, Length=218, Percent_Identity=30.7339449541284, Blast_Score=86, Evalue=3e-18, Organism=Escherichia coli, GI1789873, Length=226, Percent_Identity=29.646017699115, Blast_Score=83, Evalue=3e-17, Organism=Escherichia coli, GI1786872, Length=214, Percent_Identity=28.9719626168224, Blast_Score=83, Evalue=3e-17, Organism=Escherichia coli, GI48995001, Length=232, Percent_Identity=31.4655172413793, Blast_Score=80, Evalue=3e-16, Organism=Escherichia coli, GI1790544, Length=244, Percent_Identity=29.9180327868852, Blast_Score=78, Evalue=6e-16, Organism=Escherichia coli, GI1787792, Length=222, Percent_Identity=31.0810810810811, Blast_Score=78, Evalue=1e-15, Organism=Escherichia coli, GI1788053, Length=216, Percent_Identity=29.6296296296296, Blast_Score=78, Evalue=1e-15, Organism=Escherichia coli, GI87082267, Length=245, Percent_Identity=26.530612244898, Blast_Score=76, Evalue=3e-15, Organism=Escherichia coli, GI1790467, Length=246, Percent_Identity=26.4227642276423, Blast_Score=75, Evalue=4e-15, Organism=Escherichia coli, GI1786319, Length=241, Percent_Identity=27.8008298755187, Blast_Score=75, Evalue=5e-15, Organism=Escherichia coli, GI1790739, Length=266, Percent_Identity=27.4436090225564, Blast_Score=75, Evalue=5e-15, Organism=Escherichia coli, GI1786253, Length=246, Percent_Identity=25.609756097561, Blast_Score=75, Evalue=7e-15, Organism=Escherichia coli, GI1786654, Length=241, Percent_Identity=29.8755186721992, Blast_Score=73, Evalue=2e-14, Organism=Escherichia coli, GI1787143, Length=253, Percent_Identity=29.2490118577075, Blast_Score=72, Evalue=4e-14, Organism=Escherichia coli, GI1789586, Length=238, Percent_Identity=28.1512605042017, Blast_Score=72, Evalue=7e-14, Organism=Escherichia coli, GI1786345, Length=214, Percent_Identity=28.9719626168224, Blast_Score=72, Evalue=7e-14, Organism=Escherichia coli, GI1788165, Length=225, Percent_Identity=28.4444444444444, Blast_Score=69, Evalue=4e-13, Organism=Escherichia coli, GI1786803, Length=225, Percent_Identity=25.7777777777778, Blast_Score=69, Evalue=5e-13, Organism=Escherichia coli, GI1790190, Length=221, Percent_Identity=28.0542986425339, Blast_Score=69, Evalue=5e-13, Organism=Escherichia coli, GI1786698, Length=221, Percent_Identity=25.7918552036199, Blast_Score=69, Evalue=6e-13, Organism=Escherichia coli, GI1787164, Length=209, Percent_Identity=29.1866028708134, Blast_Score=68, Evalue=8e-13, Organism=Escherichia coli, GI1789864, Length=258, Percent_Identity=25.968992248062, Blast_Score=66, Evalue=3e-12, Organism=Escherichia coli, GI1788210, Length=230, Percent_Identity=29.5652173913043, Blast_Score=64, Evalue=1e-11, Organism=Escherichia coli, GI1790534, Length=223, Percent_Identity=27.8026905829596, Blast_Score=63, Evalue=3e-11, Organism=Escherichia coli, GI1787112, Length=251, Percent_Identity=26.6932270916335, Blast_Score=62, Evalue=4e-11, Organism=Caenorhabditis elegans, GI115534520, Length=237, Percent_Identity=31.2236286919831, Blast_Score=87, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17565938, Length=279, Percent_Identity=28.3154121863799, Blast_Score=72, Evalue=5e-13, Organism=Caenorhabditis elegans, GI193211015, Length=249, Percent_Identity=26.5060240963855, Blast_Score=72, Evalue=5e-13, Organism=Caenorhabditis elegans, GI71996809, Length=246, Percent_Identity=28.0487804878049, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI71983516, Length=225, Percent_Identity=27.1111111111111, Blast_Score=68, Evalue=6e-12, Organism=Caenorhabditis elegans, GI71983510, Length=225, Percent_Identity=27.1111111111111, Blast_Score=68, Evalue=6e-12, Organism=Caenorhabditis elegans, GI71992290, Length=261, Percent_Identity=27.5862068965517, Blast_Score=68, Evalue=8e-12, Organism=Caenorhabditis elegans, GI193211017, Length=246, Percent_Identity=29.2682926829268, Blast_Score=68, Evalue=8e-12, Organism=Caenorhabditis elegans, GI17510237, Length=217, Percent_Identity=27.1889400921659, Blast_Score=66, Evalue=3e-11, Organism=Caenorhabditis elegans, GI71996550, Length=246, Percent_Identity=29.2682926829268, Blast_Score=65, Evalue=4e-11, Organism=Caenorhabditis elegans, GI71983523, Length=235, Percent_Identity=27.2340425531915, Blast_Score=64, Evalue=8e-11, Organism=Saccharomyces cerevisiae, GI6322980, Length=257, Percent_Identity=26.0700389105058, Blast_Score=66, Evalue=6e-12, Organism=Drosophila melanogaster, GI24641565, Length=256, Percent_Identity=28.90625, Blast_Score=73, Evalue=2e-13, Organism=Drosophila melanogaster, GI21357907, Length=242, Percent_Identity=29.3388429752066, Blast_Score=72, Evalue=6e-13,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003439 - InterPro: IPR017871 - InterPro: IPR003593 - InterPro: IPR010066 - InterPro: IPR013563 [H]
Pfam domain/function: PF00005 ABC_tran; PF08352 oligo_HPY [H]
EC number: NA
Molecular weight: Translated: 35653; Mature: 35653
Theoretical pI: Translated: 7.14; Mature: 7.14
Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.5 %Cys (Translated Protein) 2.1 %Met (Translated Protein) 3.6 %Cys+Met (Translated Protein) 1.5 %Cys (Mature Protein) 2.1 %Met (Mature Protein) 3.6 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MLEVTNLSISFPHTSGRLRAVENIDFSIEKGKVLTLIGESGSGKTLTGLSLMGLLPGGAQ CEEEEEEEEECCCCCCCEEEEECCCEEECCCEEEEEEECCCCCCEEECEEEEEECCCCCE VTGRIALEGREISGLSEEKLRHIRGRDIAMVYQNPLSALNPVWPVGEQIAEAVLAHGLAT EEEEEEEECCCCCCCCHHHHHHHCCCCEEEEECCCHHHCCCCCCCHHHHHHHHHHHHHHH RHEAGQRAIALLGRVGIPGPERVSKLYPFEISGGMRQRVVIAMALACNPRLIIADEPTTA HHHHHHHHHHHHHHCCCCCHHHHHHCCCEEECCCCHHHEEEEEEEECCCEEEEECCCCCE LDVTIKAQILDLLADLVAQEQISVLLITHDMHVVARLADDILVLYAGRMAERGHVRDLLD EEEEHHHHHHHHHHHHHHHCCEEEEEEECCHHHHHHHHHHHEEEHHCCCCCCCHHHHHHH HPAHPYTAGLLRSADIRSRPPQTDLEILTGQPPRIGNFPTGCRFHPRCPSSGALCPTHSP CCCCCHHHHHHCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCEECCCCCCCCCCCCCCCC DFIQLFSSGQATACHYPAISADRLQQEQLL HHHHHCCCCCCCEEECCCCCHHHHHHHHCC >Mature Secondary Structure MLEVTNLSISFPHTSGRLRAVENIDFSIEKGKVLTLIGESGSGKTLTGLSLMGLLPGGAQ CEEEEEEEEECCCCCCCEEEEECCCEEECCCEEEEEEECCCCCCEEECEEEEEECCCCCE VTGRIALEGREISGLSEEKLRHIRGRDIAMVYQNPLSALNPVWPVGEQIAEAVLAHGLAT EEEEEEEECCCCCCCCHHHHHHHCCCCEEEEECCCHHHCCCCCCCHHHHHHHHHHHHHHH RHEAGQRAIALLGRVGIPGPERVSKLYPFEISGGMRQRVVIAMALACNPRLIIADEPTTA HHHHHHHHHHHHHHCCCCCHHHHHHCCCEEECCCCHHHEEEEEEEECCCEEEEECCCCCE LDVTIKAQILDLLADLVAQEQISVLLITHDMHVVARLADDILVLYAGRMAERGHVRDLLD EEEEHHHHHHHHHHHHHHHCCEEEEEEECCHHHHHHHHHHHEEEHHCCCCCCCHHHHHHH HPAHPYTAGLLRSADIRSRPPQTDLEILTGQPPRIGNFPTGCRFHPRCPSSGALCPTHSP CCCCCHHHHHHCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCEECCCCCCCCCCCCCCCC DFIQLFSSGQATACHYPAISADRLQQEQLL HHHHHCCCCCCCEEECCCCCHHHHHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: ATP; oligopeptides [Periplasm]; H2O [C]
Specific reaction: ATP + oligopeptides [Periplasm] + H2O = ADP + phosphate + oligopeptides [Cytoplasm] [C]
General reaction: NA
Inhibitor: NA
Structure determination priority: 7.0
TargetDB status: NA
Availability: NA
References: 7997159; 9384377 [H]