Click here to switch to the map view.

The map label for this gene is nagA [H]

Identifier: 225686670

GI number: 225686670

Start: 872316

End: 873482

Strand: Reverse

Name: nagA [H]

Synonym: BMEA_B0893

Alternate gene names: 225686670

Gene position: 873482-872316 (Counterclockwise)

Preceding gene: 225686671

Following gene: 225686669

Centisome position: 73.68

GC content: 62.38

Gene sequence:

>1167_bases
ATGATGAAGAAATCAGCAATTGCAGGCGCGCGCATCTTCGACGGTGAGCGCTTTCATGACCAGAGCGCGCTGGTATTCAG
CGATGGCCAGATCGAGGCCATCGTACCGGAAGCATCGCTTGCCGAGGGCCACGAAATCGAAAGGCTGAAGGGCGGCGTTC
TTGCCCCCGGTTTCATCGATGCGCAGGTGAATGGCGGCGGCGGGCGTATGCTCAATGACGAGCCGACGCCCGAAACCATG
TTCGTGATTGCCGGCGGGCACAGGAAATACGGCACGACCAGCCTGTTGCCGACGCTCATCACCGATACGATGCCCGTGCG
TGACCGCGCCATTGAGGCGGCGATTGAAGCGGTGAAGGCTGACAGGGGGGTTGCTGGCCTGCATCTGGAAGGCCCGCATC
TGGCGCCAGCGCGCAAAGGCGCGCATCTGGCGGAACTGATGCGCCCGGTCAATGATGCCGATATTGCGCTCTATATCCAT
ACAGCCAGGCAGATTGGCACCTTGCTGGTGACGCTCGCGGCCGAACAGGTGACGCCTGAACAGGTGCGCCGCTTGAGCGA
TGGAGGCGTGATCGTCAGCATTGGCCACAGCGACACGACCGCTGAAGAAGCCTTCCGGCGCTTCGATGCCGGTGCGCGCA
GCGTGACGCATCTTTATAATGCCATGAGCCAGATTGGTCATCGCGCGCCGGGTCTTGCCGGTGCGGCGCTCGATCATCCC
GATATCTGGTGCGGTATCGTTGCGGATGGGCATCATGTCGATCCGATGGCGCTGCGGCTGGCGCTGCGTGCCAAGCGCGG
CGATGCGCATCTGTTCCTCGTGACGGACGCCATGGCGCTTGTCGGATCGGATGCGGAAAGCTTCGAGATAAACGGGCGCA
GCGTTCGCCGTGTGCCGGGCGGCATCTGCTCCAAGCTGGTCCTGCCGGATGGCACCATTGCCGGTTCCGATCTCGACATG
GCTTCGGCGGTGCGGTTTGCCGTGGCAGAACTGGAACTGACGCTTGCCGAGGCGCTGCGCATGGCAAGCCTCTATCCGGC
GCGCTATCTGCGCCTTAATGATCGCGGCCGGTTCCGTCCGGGAATGCGCATGGATGCCGTGCATCTGGATGACGGGCTGT
TCGCCAAATCCACATGGCTTTCCGGCGAAAAGCAGATTGCAGGCTGA

Upstream 100 bases:

>100_bases
TCTCGCTCATCAATTATTACCGCGTCATAGAAGCGGTCACGCGCCGCAAGGGTTTCGATCCCGACAAGCCGCGCAATCTC
AACAAGGTTACGGTGACGGT

Downstream 100 bases:

>100_bases
GGGCGCGATGACGGAAATCACGGACCGCTATTTCAATGATGTGATTGCGCGGCTTTCGGGCCTGCGCGACCGGCTGGCCG
CGCAGATGGAAAAAGCTGCC

Product: N-acetylglucosamine-6-phosphate deacetylase

Products: NA

Alternate protein names: GlcNAc 6-P deacetylase [H]

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MMKKSAIAGARIFDGERFHDQSALVFSDGQIEAIVPEASLAEGHEIERLKGGVLAPGFIDAQVNGGGGRMLNDEPTPETM
FVIAGGHRKYGTTSLLPTLITDTMPVRDRAIEAAIEAVKADRGVAGLHLEGPHLAPARKGAHLAELMRPVNDADIALYIH
TARQIGTLLVTLAAEQVTPEQVRRLSDGGVIVSIGHSDTTAEEAFRRFDAGARSVTHLYNAMSQIGHRAPGLAGAALDHP
DIWCGIVADGHHVDPMALRLALRAKRGDAHLFLVTDAMALVGSDAESFEINGRSVRRVPGGICSKLVLPDGTIAGSDLDM
ASAVRFAVAELELTLAEALRMASLYPARYLRLNDRGRFRPGMRMDAVHLDDGLFAKSTWLSGEKQIAG

Sequences:

>Translated_388_residues
MMKKSAIAGARIFDGERFHDQSALVFSDGQIEAIVPEASLAEGHEIERLKGGVLAPGFIDAQVNGGGGRMLNDEPTPETM
FVIAGGHRKYGTTSLLPTLITDTMPVRDRAIEAAIEAVKADRGVAGLHLEGPHLAPARKGAHLAELMRPVNDADIALYIH
TARQIGTLLVTLAAEQVTPEQVRRLSDGGVIVSIGHSDTTAEEAFRRFDAGARSVTHLYNAMSQIGHRAPGLAGAALDHP
DIWCGIVADGHHVDPMALRLALRAKRGDAHLFLVTDAMALVGSDAESFEINGRSVRRVPGGICSKLVLPDGTIAGSDLDM
ASAVRFAVAELELTLAEALRMASLYPARYLRLNDRGRFRPGMRMDAVHLDDGLFAKSTWLSGEKQIAG
>Mature_388_residues
MMKKSAIAGARIFDGERFHDQSALVFSDGQIEAIVPEASLAEGHEIERLKGGVLAPGFIDAQVNGGGGRMLNDEPTPETM
FVIAGGHRKYGTTSLLPTLITDTMPVRDRAIEAAIEAVKADRGVAGLHLEGPHLAPARKGAHLAELMRPVNDADIALYIH
TARQIGTLLVTLAAEQVTPEQVRRLSDGGVIVSIGHSDTTAEEAFRRFDAGARSVTHLYNAMSQIGHRAPGLAGAALDHP
DIWCGIVADGHHVDPMALRLALRAKRGDAHLFLVTDAMALVGSDAESFEINGRSVRRVPGGICSKLVLPDGTIAGSDLDM
ASAVRFAVAELELTLAEALRMASLYPARYLRLNDRGRFRPGMRMDAVHLDDGLFAKSTWLSGEKQIAG

Specific function: N-acetylglucosamine utilization. [C]

COG id: COG1820

COG function: function code G; N-acetylglucosamine-6-phosphate deacetylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nagA family [H]

Homologues:

Organism=Homo sapiens, GI21361513, Length=374, Percent_Identity=32.3529411764706, Blast_Score=125, Evalue=5e-29,
Organism=Homo sapiens, GI224922791, Length=373, Percent_Identity=32.171581769437, Blast_Score=122, Evalue=7e-28,
Organism=Escherichia coli, GI1786892, Length=354, Percent_Identity=41.8079096045198, Blast_Score=233, Evalue=2e-62,
Organism=Caenorhabditis elegans, GI17553768, Length=356, Percent_Identity=30.3370786516854, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI19920392, Length=341, Percent_Identity=33.1378299120235, Blast_Score=152, Evalue=4e-37,
Organism=Drosophila melanogaster, GI281361140, Length=355, Percent_Identity=32.3943661971831, Blast_Score=151, Evalue=6e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR003764
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.1.25 [H]

Molecular weight: Translated: 41463; Mature: 41463

Theoretical pI: Translated: 6.46; Mature: 6.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKKSAIAGARIFDGERFHDQSALVFSDGQIEAIVPEASLAEGHEIERLKGGVLAPGFID
CCCCHHCCCCEEECCCCCCCCCEEEEECCCEEEECCCCCCCCCCHHHHHCCCEECCCEEE
AQVNGGGGRMLNDEPTPETMFVIAGGHRKYGTTSLLPTLITDTMPVRDRAIEAAIEAVKA
EEEECCCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHH
DRGVAGLHLEGPHLAPARKGAHLAELMRPVNDADIALYIHTARQIGTLLVTLAAEQVTPE
CCCEEEEEECCCCCCCCCCCHHHHHHHCCCCCCCEEEEEEEHHHHHHHHHHHHHHCCCHH
QVRRLSDGGVIVSIGHSDTTAEEAFRRFDAGARSVTHLYNAMSQIGHRAPGLAGAALDHP
HHHHCCCCCEEEEECCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
DIWCGIVADGHHVDPMALRLALRAKRGDAHLFLVTDAMALVGSDAESFEINGRSVRRVPG
CEEEEEEECCCCCCHHHHHHHHHHCCCCEEEEEEEHHHHHHCCCCCEEEECCCEEECCCC
GICSKLVLPDGTIAGSDLDMASAVRFAVAELELTLAEALRMASLYPARYLRLNDRGRFRP
HHHHEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCC
GMRMDAVHLDDGLFAKSTWLSGEKQIAG
CCEEEEEECCCCCEEEHHCCCCCCCCCC
>Mature Secondary Structure
MMKKSAIAGARIFDGERFHDQSALVFSDGQIEAIVPEASLAEGHEIERLKGGVLAPGFID
CCCCHHCCCCEEECCCCCCCCCEEEEECCCEEEECCCCCCCCCCHHHHHCCCEECCCEEE
AQVNGGGGRMLNDEPTPETMFVIAGGHRKYGTTSLLPTLITDTMPVRDRAIEAAIEAVKA
EEEECCCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHH
DRGVAGLHLEGPHLAPARKGAHLAELMRPVNDADIALYIHTARQIGTLLVTLAAEQVTPE
CCCEEEEEECCCCCCCCCCCHHHHHHHCCCCCCCEEEEEEEHHHHHHHHHHHHHHCCCHH
QVRRLSDGGVIVSIGHSDTTAEEAFRRFDAGARSVTHLYNAMSQIGHRAPGLAGAALDHP
HHHHCCCCCEEEEECCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
DIWCGIVADGHHVDPMALRLALRAKRGDAHLFLVTDAMALVGSDAESFEINGRSVRRVPG
CEEEEEEECCCCCCHHHHHHHHHHCCCCEEEEEEEHHHHHHCCCCCEEEECCCEEECCCC
GICSKLVLPDGTIAGSDLDMASAVRFAVAELELTLAEALRMASLYPARYLRLNDRGRFRP
HHHHEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCC
GMRMDAVHLDDGLFAKSTWLSGEKQIAG
CCEEEEEECCCCCEEEHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9301118; 10952301 [H]