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The map label for this gene is uxuA [H]

Identifier: 225686577

GI number: 225686577

Start: 778034

End: 779239

Strand: Direct

Name: uxuA [H]

Synonym: BMEA_B0793

Alternate gene names: 225686577

Gene position: 778034-779239 (Clockwise)

Preceding gene: 225686576

Following gene: 225686580

Centisome position: 65.63

GC content: 55.64

Gene sequence:

>1206_bases
ATGCGTCAGGCATGGAGATGGTTTGGGCCGGAAGCTGGCGTTCCGCTGGATGCGGTGCGCCAGGCCGGAGCAACGGATAT
CGTTTCGGCACTGCATGAAGTTCCAATCGGCCAGGAATGGACGTCAGCCCAGATTGTCGAGCGCAAGAACCTGATCGAAA
GCACGCCCACCGGGCGGCATCCCCTCACATGGTCCGTGGTCGAGAGCATTCCTGTTTCCGACGACATCAAGCGGAGCGGT
AAAGCCGCCCGACATGATATTGGTGCCTGGATAGCCAGCATGGAGGCGCTGGCCCGCAATGATATCAAAGTCATCTGCTA
TAATTTCATGCCGGTCGTCGATTGGTGCCGCACCGACCTTGATTACATAACCTCGACAGGCGCAACGGCAATGCGCTTTG
ATCAGGACCGGTTTGCGGCTTTCGATCTGCATATTTTACGGCGCAAAGGGGCCGAGAAGGACTATAGCGAGGAGGATCGC
ATCGCCGCCAGAGCAATCTTCGAGGCAATGGACGAGACGGAGATCGAGCAGCTCATCGTTAATATAGCCAGTGCTTTGCC
TGGCTCCACGACCGAGCCGCTGACCATTCCCGCATTTCGTAAAAAGCTGGAAACCTATGCCAGTATCGATGCAGCGCACT
TGCGCCGGAATCTGGTCGAATTCCTTGAAGCTGTAACGCCTGTGGCAGATTCGCTGGGCGTGAAATTAACCTTGCATCCA
GATGATCCGCCGCGTTCGCTTTTTGGTTTGCCGCGTATAGCATCCACGGAAGCCGACTATGCGGCAATTTTTGCCGCTGT
GCCTGCCCAATCCAACGGTATGTGTTTTTGTACGGGAAGCCTCGGTGTTCGTGCCGACAACGACCTGCCTGCCATTGCCC
GGCGTTTTGCGTCCCGCATTCATTTCTCACATCTGCGTGCAACAACGCGCGAAGGCGATGGGCGTACTTTTCACGAGGCA
GCCCATCTGGAAGGCGACGTGGATATGGTTGGTATCCTGCGTATACTGCTTGAGGAAGACCGGAAACGGGATGCGGGACA
GACAATTATTTTTCGATCCGATCACGGCCATCGCATGATGGACGACCTGGAGAAAAAGGTTACGCCAGGTTATCCCGTTA
TTGGCCGAATGCGCGGACTGGCAGAACTACGTGGCATCATCACTGCCCTTGATGCCTGTGCGCTGGAATATGACCCAAAC
GTTTAG

Upstream 100 bases:

>100_bases
TGACGAGTTGCGCAAAAGCCGTCCGGACTATTTTGCTTGATAGCTGATAGGCAGGCGTTTTTCCCTAACAATCAAAAGAA
CATGGCGAGGAGAGGATTGA

Downstream 100 bases:

>100_bases
AGCGCGTTTCGATCTGATTGAATCAGATCGGCGCTCTAATTCTTTGTTTTGACGCGCATCTTTTCCGAAAACCGTTTCAC
ACTTTTCGGGATGCGCGCTA

Product: mannonate dehydratase

Products: NA

Alternate protein names: D-mannonate hydrolase [H]

Number of amino acids: Translated: 401; Mature: 401

Protein sequence:

>401_residues
MRQAWRWFGPEAGVPLDAVRQAGATDIVSALHEVPIGQEWTSAQIVERKNLIESTPTGRHPLTWSVVESIPVSDDIKRSG
KAARHDIGAWIASMEALARNDIKVICYNFMPVVDWCRTDLDYITSTGATAMRFDQDRFAAFDLHILRRKGAEKDYSEEDR
IAARAIFEAMDETEIEQLIVNIASALPGSTTEPLTIPAFRKKLETYASIDAAHLRRNLVEFLEAVTPVADSLGVKLTLHP
DDPPRSLFGLPRIASTEADYAAIFAAVPAQSNGMCFCTGSLGVRADNDLPAIARRFASRIHFSHLRATTREGDGRTFHEA
AHLEGDVDMVGILRILLEEDRKRDAGQTIIFRSDHGHRMMDDLEKKVTPGYPVIGRMRGLAELRGIITALDACALEYDPN
V

Sequences:

>Translated_401_residues
MRQAWRWFGPEAGVPLDAVRQAGATDIVSALHEVPIGQEWTSAQIVERKNLIESTPTGRHPLTWSVVESIPVSDDIKRSG
KAARHDIGAWIASMEALARNDIKVICYNFMPVVDWCRTDLDYITSTGATAMRFDQDRFAAFDLHILRRKGAEKDYSEEDR
IAARAIFEAMDETEIEQLIVNIASALPGSTTEPLTIPAFRKKLETYASIDAAHLRRNLVEFLEAVTPVADSLGVKLTLHP
DDPPRSLFGLPRIASTEADYAAIFAAVPAQSNGMCFCTGSLGVRADNDLPAIARRFASRIHFSHLRATTREGDGRTFHEA
AHLEGDVDMVGILRILLEEDRKRDAGQTIIFRSDHGHRMMDDLEKKVTPGYPVIGRMRGLAELRGIITALDACALEYDPN
V
>Mature_401_residues
MRQAWRWFGPEAGVPLDAVRQAGATDIVSALHEVPIGQEWTSAQIVERKNLIESTPTGRHPLTWSVVESIPVSDDIKRSG
KAARHDIGAWIASMEALARNDIKVICYNFMPVVDWCRTDLDYITSTGATAMRFDQDRFAAFDLHILRRKGAEKDYSEEDR
IAARAIFEAMDETEIEQLIVNIASALPGSTTEPLTIPAFRKKLETYASIDAAHLRRNLVEFLEAVTPVADSLGVKLTLHP
DDPPRSLFGLPRIASTEADYAAIFAAVPAQSNGMCFCTGSLGVRADNDLPAIARRFASRIHFSHLRATTREGDGRTFHEA
AHLEGDVDMVGILRILLEEDRKRDAGQTIIFRSDHGHRMMDDLEKKVTPGYPVIGRMRGLAELRGIITALDACALEYDPN
V

Specific function: Hexuronate conversion to KDG. [C]

COG id: COG1312

COG function: function code G; D-mannonate dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mannonate dehydratase family [H]

Homologues:

Organism=Escherichia coli, GI1790778, Length=393, Percent_Identity=48.6005089058524, Blast_Score=392, Evalue=1e-110,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004628
- InterPro:   IPR013022 [H]

Pfam domain/function: PF03786 UxuA [H]

EC number: =4.2.1.8 [H]

Molecular weight: Translated: 44473; Mature: 44473

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRQAWRWFGPEAGVPLDAVRQAGATDIVSALHEVPIGQEWTSAQIVERKNLIESTPTGRH
CCCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCC
PLTWSVVESIPVSDDIKRSGKAARHDIGAWIASMEALARNDIKVICYNFMPVVDWCRTDL
CEEHHHHHCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHCCH
DYITSTGATAMRFDQDRFAAFDLHILRRKGAEKDYSEEDRIAARAIFEAMDETEIEQLIV
HHHHCCCCHHEEECCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHH
NIASALPGSTTEPLTIPAFRKKLETYASIDAAHLRRNLVEFLEAVTPVADSLGVKLTLHP
HHHHHCCCCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECC
DDPPRSLFGLPRIASTEADYAAIFAAVPAQSNGMCFCTGSLGVRADNDLPAIARRFASRI
CCCCHHHHCCCCCCCCCCCHHHHEEECCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHH
HFSHLRATTREGDGRTFHEAAHLEGDVDMVGILRILLEEDRKRDAGQTIIFRSDHGHRMM
HHHHHHHHCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHH
DDLEKKVTPGYPVIGRMRGLAELRGIITALDACALEYDPNV
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MRQAWRWFGPEAGVPLDAVRQAGATDIVSALHEVPIGQEWTSAQIVERKNLIESTPTGRH
CCCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCC
PLTWSVVESIPVSDDIKRSGKAARHDIGAWIASMEALARNDIKVICYNFMPVVDWCRTDL
CEEHHHHHCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHCCH
DYITSTGATAMRFDQDRFAAFDLHILRRKGAEKDYSEEDRIAARAIFEAMDETEIEQLIV
HHHHCCCCHHEEECCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHH
NIASALPGSTTEPLTIPAFRKKLETYASIDAAHLRRNLVEFLEAVTPVADSLGVKLTLHP
HHHHHCCCCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECC
DDPPRSLFGLPRIASTEADYAAIFAAVPAQSNGMCFCTGSLGVRADNDLPAIARRFASRI
CCCCHHHHCCCCCCCCCCCHHHHEEECCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHH
HFSHLRATTREGDGRTFHEAAHLEGDVDMVGILRILLEEDRKRDAGQTIIFRSDHGHRMM
HHHHHHHHCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHH
DDLEKKVTPGYPVIGRMRGLAELRGIITALDACALEYDPNV
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA