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The map label for this gene is lysK [H]

Identifier: 225686557

GI number: 225686557

Start: 750340

End: 751995

Strand: Direct

Name: lysK [H]

Synonym: BMEA_B0769

Alternate gene names: 225686557

Gene position: 750340-751995 (Clockwise)

Preceding gene: 225686555

Following gene: 225686564

Centisome position: 63.29

GC content: 56.88

Gene sequence:

>1656_bases
ATGACCTCGCACCGCCTTCCCGAAATTACGCTGACCCCGGAACTGACCGCGGCGGCGGCGGAAGCGAAAGCATGGCCTTT
TGAAGAGGCAAGAAAAATCCTCAAGCGTTACGCCAAAACCGGCCTGCCCGAAACGGTGATCTTTGAAACCGGCTATGGCC
CTTCAGGCCTGCCGCATATCGGCACATTCGGTGAAGTGGCGCGCACCTCGATGGTGCGCCATGCCTTTCGCATTTTGACG
CAAGACAAGGTGAAGACGCGCCTCATCTGCTTTTCCGACGATCTCGACGGAATGCGCAAGGTGCCCGACAATGTGCCGGA
CAGGGCCGCGCTCGAACCCTATCTGCAAATGCCGCTTTCCTCGGTGCCGAACCCGTTCGGTGGCGATTACAAGAGCTTTG
CCGAACACAATAATGCGATGCTGTGCCGCTTCCTCGACACTTTCGGCTTCGATTACGAGTTCGCCAGTGCGACAGAATAT
TACCGCTCCGGCAGGTTCGATACGGTGCTGCTCAAGGCCGTGGAACGCTATGACGACATCATGAAGGTGATGCTGCCGAC
GCTGGGCGAAGAACGCCAAGCGACCTACAGCCCCTTCCTGCCGATTTCGCCCAAGTCCAGGCGAGTGCTTTATGTGCCGA
TGAAAAAGGTGGACGCCAAGGCGGGTACCATCACCTTTGATGATGAAGACGGTGAGGAAACCACGCTTTCCGTCACTGGC
GGCAAGGTGAAATTGCAGTGGAAGCCGGATTTCGGTATGCGCTGGGCGGCTCTTGGCGTCGATTTTGAAATGTTCGGCAA
GGACCACCAGACGAATGCGGGCATTTACGACCGTATCTGCGAAATTCTTGGCGGGCGCGCGCCGGAGCATTTTGTCTATG
AACTGTTCCTCGACCAGCTTGGCCAAAAGATTTCCAAGTCCAAGGGCAACGGTATTTCCATTGATGAATGGCTGGCCTAT
GCGCCGACCGAAAGCCTCGCGCTCTATAATTTCCAGAAGCCGAAAACCGCAAAGAAGCTCTATTTCGATGTGATCCCGAA
GACGGTGGATGAATATTTCACCTATTTGTCAGCCTATGCGCGTCAGGAATGGAAAGACCGGCTGAACAATCCGGTCTGGC
ACATCCATTACGGCAATCCTCCGAAGGCGGACCTGCCGGTTACTTTTGCACTGATGCTCAATCTTGTGAGTGCATCGAAT
GCCGAAAGCCCGGCCGTCCTCTGGGGCTTCATCTCGCGCCATGTGCCGGGCGTCACACCGGAAAACAACCCGGAACTCGA
CGCGCTCGTGGGTTATGCGATCCGTTACTTCAACGATTTCGTGAAGCCGACCAAGAAATTCCGCGCACCCGACGATGTGG
AGCGCGCGGCACTCGAAGCACTGGATGCCAAGCTGGGCGAACTGCCTGCGGGAACCGATGGCAATGTCATCCAAAACGCC
ATTCTGGATGTGGCCCGCGCCATCGAACGCTATCAGGACCACACCAAGAAGAGCCCGGAAGGCGGCCCCGGCGTGTCGGT
TTCCTTCTTCCAGATGCTCTATGAAGTGCTGATCGGTCAGGAGCGCGGTCCCCGCTTCGGCTCCTTCGTTGCGCTTTACG
GTATCGACGAAACCCGTGCGCTCATCAAAAAGGCGCTGGCTGGCGAACTGGCGTAA

Upstream 100 bases:

>100_bases
GTCGCGACCGTTGACGGATAGTGGTTGCCGCGCCATAGAGCAATAGCGCCTTGCATGCGCACAAGTTTTCAACGGATAAC
GCCCTTCACAGGATAAAACC

Downstream 100 bases:

>100_bases
CCATCAAGACAGGAAATGAAAAAGCTCCGCATCGTGCGGGGCTTTTTCGTTGTATGAGCGGAACTGAAAGGGGCTCAGCC
CCATTCGTCATTGTGCTGCG

Product: lysyl-tRNA synthetase

Products: NA

Alternate protein names: Lysine--tRNA ligase; LysRS [H]

Number of amino acids: Translated: 551; Mature: 550

Protein sequence:

>551_residues
MTSHRLPEITLTPELTAAAAEAKAWPFEEARKILKRYAKTGLPETVIFETGYGPSGLPHIGTFGEVARTSMVRHAFRILT
QDKVKTRLICFSDDLDGMRKVPDNVPDRAALEPYLQMPLSSVPNPFGGDYKSFAEHNNAMLCRFLDTFGFDYEFASATEY
YRSGRFDTVLLKAVERYDDIMKVMLPTLGEERQATYSPFLPISPKSRRVLYVPMKKVDAKAGTITFDDEDGEETTLSVTG
GKVKLQWKPDFGMRWAALGVDFEMFGKDHQTNAGIYDRICEILGGRAPEHFVYELFLDQLGQKISKSKGNGISIDEWLAY
APTESLALYNFQKPKTAKKLYFDVIPKTVDEYFTYLSAYARQEWKDRLNNPVWHIHYGNPPKADLPVTFALMLNLVSASN
AESPAVLWGFISRHVPGVTPENNPELDALVGYAIRYFNDFVKPTKKFRAPDDVERAALEALDAKLGELPAGTDGNVIQNA
ILDVARAIERYQDHTKKSPEGGPGVSVSFFQMLYEVLIGQERGPRFGSFVALYGIDETRALIKKALAGELA

Sequences:

>Translated_551_residues
MTSHRLPEITLTPELTAAAAEAKAWPFEEARKILKRYAKTGLPETVIFETGYGPSGLPHIGTFGEVARTSMVRHAFRILT
QDKVKTRLICFSDDLDGMRKVPDNVPDRAALEPYLQMPLSSVPNPFGGDYKSFAEHNNAMLCRFLDTFGFDYEFASATEY
YRSGRFDTVLLKAVERYDDIMKVMLPTLGEERQATYSPFLPISPKSRRVLYVPMKKVDAKAGTITFDDEDGEETTLSVTG
GKVKLQWKPDFGMRWAALGVDFEMFGKDHQTNAGIYDRICEILGGRAPEHFVYELFLDQLGQKISKSKGNGISIDEWLAY
APTESLALYNFQKPKTAKKLYFDVIPKTVDEYFTYLSAYARQEWKDRLNNPVWHIHYGNPPKADLPVTFALMLNLVSASN
AESPAVLWGFISRHVPGVTPENNPELDALVGYAIRYFNDFVKPTKKFRAPDDVERAALEALDAKLGELPAGTDGNVIQNA
ILDVARAIERYQDHTKKSPEGGPGVSVSFFQMLYEVLIGQERGPRFGSFVALYGIDETRALIKKALAGELA
>Mature_550_residues
TSHRLPEITLTPELTAAAAEAKAWPFEEARKILKRYAKTGLPETVIFETGYGPSGLPHIGTFGEVARTSMVRHAFRILTQ
DKVKTRLICFSDDLDGMRKVPDNVPDRAALEPYLQMPLSSVPNPFGGDYKSFAEHNNAMLCRFLDTFGFDYEFASATEYY
RSGRFDTVLLKAVERYDDIMKVMLPTLGEERQATYSPFLPISPKSRRVLYVPMKKVDAKAGTITFDDEDGEETTLSVTGG
KVKLQWKPDFGMRWAALGVDFEMFGKDHQTNAGIYDRICEILGGRAPEHFVYELFLDQLGQKISKSKGNGISIDEWLAYA
PTESLALYNFQKPKTAKKLYFDVIPKTVDEYFTYLSAYARQEWKDRLNNPVWHIHYGNPPKADLPVTFALMLNLVSASNA
ESPAVLWGFISRHVPGVTPENNPELDALVGYAIRYFNDFVKPTKKFRAPDDVERAALEALDAKLGELPAGTDGNVIQNAI
LDVARAIERYQDHTKKSPEGGPGVSVSFFQMLYEVLIGQERGPRFGSFVALYGIDETRALIKKALAGELA

Specific function: Unknown

COG id: COG1384

COG function: function code J; Lysyl-tRNA synthetase (class I)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008925
- InterPro:   IPR020751
- InterPro:   IPR001412
- InterPro:   IPR002904
- InterPro:   IPR020754
- InterPro:   IPR020756
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01921 tRNA-synt_1f [H]

EC number: =6.1.1.6 [H]

Molecular weight: Translated: 61769; Mature: 61638

Theoretical pI: Translated: 6.22; Mature: 6.22

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSHRLPEITLTPELTAAAAEAKAWPFEEARKILKRYAKTGLPETVIFETGYGPSGLPHI
CCCCCCCCEEECCCHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCC
GTFGEVARTSMVRHAFRILTQDKVKTRLICFSDDLDGMRKVPDNVPDRAALEPYLQMPLS
CCHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHCCCCCCCHHHHHHHHHCCHH
SVPNPFGGDYKSFAEHNNAMLCRFLDTFGFDYEFASATEYYRSGRFDTVLLKAVERYDDI
HCCCCCCCCHHHHHHCCCCEEEHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHH
MKVMLPTLGEERQATYSPFLPISPKSRRVLYVPMKKVDAKAGTITFDDEDGEETTLSVTG
HHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEECHHHCCCCCCEEEECCCCCCCEEEEEEC
GKVKLQWKPDFGMRWAALGVDFEMFGKDHQTNAGIYDRICEILGGRAPEHFVYELFLDQL
CEEEEEECCCCCCEEEEECCCHHHHCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHH
GQKISKSKGNGISIDEWLAYAPTESLALYNFQKPKTAKKLYFDVIPKTVDEYFTYLSAYA
HHHHHHCCCCCCCHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
RQEWKDRLNNPVWHIHYGNPPKADLPVTFALMLNLVSASNAESPAVLWGFISRHVPGVTP
HHHHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCC
ENNPELDALVGYAIRYFNDFVKPTKKFRAPDDVERAALEALDAKLGELPAGTDGNVIQNA
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
ILDVARAIERYQDHTKKSPEGGPGVSVSFFQMLYEVLIGQERGPRFGSFVALYGIDETRA
HHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEECCCHHHH
LIKKALAGELA
HHHHHHHCCCC
>Mature Secondary Structure 
TSHRLPEITLTPELTAAAAEAKAWPFEEARKILKRYAKTGLPETVIFETGYGPSGLPHI
CCCCCCCEEECCCHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCC
GTFGEVARTSMVRHAFRILTQDKVKTRLICFSDDLDGMRKVPDNVPDRAALEPYLQMPLS
CCHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHCCCCCCCHHHHHHHHHCCHH
SVPNPFGGDYKSFAEHNNAMLCRFLDTFGFDYEFASATEYYRSGRFDTVLLKAVERYDDI
HCCCCCCCCHHHHHHCCCCEEEHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHH
MKVMLPTLGEERQATYSPFLPISPKSRRVLYVPMKKVDAKAGTITFDDEDGEETTLSVTG
HHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEECHHHCCCCCCEEEECCCCCCCEEEEEEC
GKVKLQWKPDFGMRWAALGVDFEMFGKDHQTNAGIYDRICEILGGRAPEHFVYELFLDQL
CEEEEEECCCCCCEEEEECCCHHHHCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHH
GQKISKSKGNGISIDEWLAYAPTESLALYNFQKPKTAKKLYFDVIPKTVDEYFTYLSAYA
HHHHHHCCCCCCCHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
RQEWKDRLNNPVWHIHYGNPPKADLPVTFALMLNLVSASNAESPAVLWGFISRHVPGVTP
HHHHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCC
ENNPELDALVGYAIRYFNDFVKPTKKFRAPDDVERAALEALDAKLGELPAGTDGNVIQNA
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
ILDVARAIERYQDHTKKSPEGGPGVSVSFFQMLYEVLIGQERGPRFGSFVALYGIDETRA
HHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEECCCHHHH
LIKKALAGELA
HHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11756688 [H]