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The map label for this gene is can [H]

Identifier: 225686555

GI number: 225686555

Start: 749014

End: 749673

Strand: Direct

Name: can [H]

Synonym: BMEA_B0767

Alternate gene names: 225686555

Gene position: 749014-749673 (Clockwise)

Preceding gene: 225686554

Following gene: 225686557

Centisome position: 63.18

GC content: 55.45

Gene sequence:

>660_bases
ATGCCCATGAAGAACGATCATTCGCCAGACCAGCGCACTTTATCGGAGCTTTTCGAGCATAACCGTCAATGGGCAGCAGA
AAAGCAGGAGAAAGACCCTGAATATTTCAGCCGCCTGTCATCGTCGCAGCGCCCGGAATTTCTATGGATCGGCTGTTCGG
ACAGCCGCGTTCCGGCCAATGTGGTGACGGGCCTTCAGCCGGGCGAAGTCTTCGTCCACCGTAATGTCGCCAATCTCGTC
CACCGTGCCGATCTCAACCTGCTTTCCGTTCTGGAATTCGCCGTCGGGGTTCTGGAAATCAAGCATATCATCGTTTGCGG
ACATTATGGCTGCGGTGGGGTGCGCGCGGCAATGGATGGCTATGGCCATGGCATCATCGACAATTGGCTGCAACCCATTC
GCGATATTGCGCAGGCCAATCAGGCGGAACTGGACACCATAGAAAACACGCAGGACCGGCTGGACCGGCTTTGCGAATTG
AGCGTTTCATCGCAGGTGGAAAGCCTGTCACGCACGCCGGTTCTGCAATCGGCCTGGAAGGACGGAAAGGATATCATCGT
CCATGGCTGGATGTATAATCTGAAAGATGGGCTACTGCGCGATATCGGTTGCGACTGCACCCGCAATGCCTTGCAATTTG
CCTGCCAACCGGCAGAATAA

Upstream 100 bases:

>100_bases
GCCGCCCGGATTCAAATGCACTCAATTTCATGCGCCTTGCCATGCTGGAACCAAAGTTGATTGAACGCAATTACTGATTT
TCCAGATTCGTTTAGGTTGC

Downstream 100 bases:

>100_bases
TTGCTGGAACATTTCCGGTAAAAGCGTGAAACGGCTTTGCCGGAAATGCTCTCCCCTTGATTTACAGCTTGCGGAAACGC
ACCCGGGCGCTGCGTTCGAT

Product: carbonate dehydratase

Products: NA

Alternate protein names: Carbonate dehydratase 2 [H]

Number of amino acids: Translated: 219; Mature: 218

Protein sequence:

>219_residues
MPMKNDHSPDQRTLSELFEHNRQWAAEKQEKDPEYFSRLSSSQRPEFLWIGCSDSRVPANVVTGLQPGEVFVHRNVANLV
HRADLNLLSVLEFAVGVLEIKHIIVCGHYGCGGVRAAMDGYGHGIIDNWLQPIRDIAQANQAELDTIENTQDRLDRLCEL
SVSSQVESLSRTPVLQSAWKDGKDIIVHGWMYNLKDGLLRDIGCDCTRNALQFACQPAE

Sequences:

>Translated_219_residues
MPMKNDHSPDQRTLSELFEHNRQWAAEKQEKDPEYFSRLSSSQRPEFLWIGCSDSRVPANVVTGLQPGEVFVHRNVANLV
HRADLNLLSVLEFAVGVLEIKHIIVCGHYGCGGVRAAMDGYGHGIIDNWLQPIRDIAQANQAELDTIENTQDRLDRLCEL
SVSSQVESLSRTPVLQSAWKDGKDIIVHGWMYNLKDGLLRDIGCDCTRNALQFACQPAE
>Mature_218_residues
PMKNDHSPDQRTLSELFEHNRQWAAEKQEKDPEYFSRLSSSQRPEFLWIGCSDSRVPANVVTGLQPGEVFVHRNVANLVH
RADLNLLSVLEFAVGVLEIKHIIVCGHYGCGGVRAAMDGYGHGIIDNWLQPIRDIAQANQAELDTIENTQDRLDRLCELS
VSSQVESLSRTPVLQSAWKDGKDIIVHGWMYNLKDGLLRDIGCDCTRNALQFACQPAE

Specific function: Unknown

COG id: COG0288

COG function: function code P; Carbonic anhydrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-class carbonic anhydrase family [H]

Homologues:

Organism=Escherichia coli, GI1786318, Length=196, Percent_Identity=52.0408163265306, Blast_Score=216, Evalue=7e-58,
Organism=Escherichia coli, GI1786534, Length=212, Percent_Identity=26.8867924528302, Blast_Score=84, Evalue=6e-18,
Organism=Saccharomyces cerevisiae, GI6324292, Length=198, Percent_Identity=30.8080808080808, Blast_Score=113, Evalue=3e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001765
- InterPro:   IPR015892 [H]

Pfam domain/function: PF00484 Pro_CA [H]

EC number: =4.2.1.1 [H]

Molecular weight: Translated: 24625; Mature: 24494

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: PS00704 PROK_CO2_ANHYDRASE_1 ; PS00705 PROK_CO2_ANHYDRASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPMKNDHSPDQRTLSELFEHNRQWAAEKQEKDPEYFSRLSSSQRPEFLWIGCSDSRVPAN
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCEEEEECCCCCCCHH
VVTGLQPGEVFVHRNVANLVHRADLNLLSVLEFAVGVLEIKHIIVCGHYGCGGVRAAMDG
HHCCCCCCHHEEEHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHC
YGHGIIDNWLQPIRDIAQANQAELDTIENTQDRLDRLCELSVSSQVESLSRTPVLQSAWK
CCCHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHC
DGKDIIVHGWMYNLKDGLLRDIGCDCTRNALQFACQPAE
CCCEEEEECHHHHHHHHHHHHHCCCHHHHHHHHHCCCCC
>Mature Secondary Structure 
PMKNDHSPDQRTLSELFEHNRQWAAEKQEKDPEYFSRLSSSQRPEFLWIGCSDSRVPAN
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCEEEEECCCCCCCHH
VVTGLQPGEVFVHRNVANLVHRADLNLLSVLEFAVGVLEIKHIIVCGHYGCGGVRAAMDG
HHCCCCCCHHEEEHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHC
YGHGIIDNWLQPIRDIAQANQAELDTIENTQDRLDRLCELSVSSQVESLSRTPVLQSAWK
CCCHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHC
DGKDIIVHGWMYNLKDGLLRDIGCDCTRNALQFACQPAE
CCCEEEEECHHHHHHHHHHHHHCCCHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8202364; 9278503; 10493123 [H]