Click here to switch to the map view.

The map label for this gene is pcaI [H]

Identifier: 225686418

GI number: 225686418

Start: 598703

End: 599410

Strand: Reverse

Name: pcaI [H]

Synonym: BMEA_B0611

Alternate gene names: 225686418

Gene position: 599410-598703 (Counterclockwise)

Preceding gene: 225686420

Following gene: 225686417

Centisome position: 50.56

GC content: 57.91

Gene sequence:

>708_bases
ATGGACAAGACGATAGGAAGCGCAGCGGAGGCGGTTGCGGAAATCGGCGATGGCGCGACCGTCATGATCGGCGGATTTGG
TGGCTCCGGTGCGCCGATCGAGCTCATTCATGCGCTGATTGACAAAGGGTCGAAAGGACTCACCGTTATCAACAACAATG
CGGGTAACGGGCGCATAGGCATTGCCGCCATGATCGATGCGGGCATGGTCAGGAAGATGATTTGTTCATTTCCACGCTCG
TCTGATCCGCGTGCTTTCACGGATAGATATCTGGCGGGTGAAATTGAACTGGAGCTCGTGCCGCAGGGCACGCTTGCCGA
GCGCATGCGCGCGGGCGGGGCGGGCATTCCGGCTTTCTATACACCGACCGCCTATGGCACTGAGCTTGCGGATGGCAAGG
TCATCGCCGAGTTCGATGGGCGCCCTTATGTGCAGGAACGCTGGCTGAAGGCTGATTTTGCGCTTGTCAAAGCGCATCTG
GGCGATAGCCACGGCAATCTCACCTATCGGATGGCTGCACGCAATTTCAATCCGCTGATGTGCATGGCGGCTGCAAAAAC
CATCGTGCAGGTTTCCCGCATCGTGCCGCTTGGCGGCATAGAGCCGGAAAATGTCATCACCCCCGGCATTTTCGTGGACC
GTGTGGTGGAAATCGCCAACCCGCAGCAGGAAGAAGAGCTTATTCGGGCAGGAGTGGCCTACATATGA

Upstream 100 bases:

>100_bases
GCGATGGATAAATCGGGGCGGATCAAGGCCCCCGGCACGGACAAAAGCATGGCGCGGCCTGTGGGCTTTCTCTCGCCGCG
GCGAAGTGGAGGAGATGTTT

Downstream 100 bases:

>100_bases
CCATCGATACGCTTGAAGACATCAAGCTTTCCAATGCCCAGATTGCCTGGCGCGCGGCGCAGGATATTGCCGACGGCGCC
TATGTGAACCTTGGGATCGG

Product: 3-oxoacid CoA-transferase, A subunit

Products: NA

Alternate protein names: Beta-ketoadipate:succinyl-CoA transferase subunit A [H]

Number of amino acids: Translated: 235; Mature: 235

Protein sequence:

>235_residues
MDKTIGSAAEAVAEIGDGATVMIGGFGGSGAPIELIHALIDKGSKGLTVINNNAGNGRIGIAAMIDAGMVRKMICSFPRS
SDPRAFTDRYLAGEIELELVPQGTLAERMRAGGAGIPAFYTPTAYGTELADGKVIAEFDGRPYVQERWLKADFALVKAHL
GDSHGNLTYRMAARNFNPLMCMAAAKTIVQVSRIVPLGGIEPENVITPGIFVDRVVEIANPQQEEELIRAGVAYI

Sequences:

>Translated_235_residues
MDKTIGSAAEAVAEIGDGATVMIGGFGGSGAPIELIHALIDKGSKGLTVINNNAGNGRIGIAAMIDAGMVRKMICSFPRS
SDPRAFTDRYLAGEIELELVPQGTLAERMRAGGAGIPAFYTPTAYGTELADGKVIAEFDGRPYVQERWLKADFALVKAHL
GDSHGNLTYRMAARNFNPLMCMAAAKTIVQVSRIVPLGGIEPENVITPGIFVDRVVEIANPQQEEELIRAGVAYI
>Mature_235_residues
MDKTIGSAAEAVAEIGDGATVMIGGFGGSGAPIELIHALIDKGSKGLTVINNNAGNGRIGIAAMIDAGMVRKMICSFPRS
SDPRAFTDRYLAGEIELELVPQGTLAERMRAGGAGIPAFYTPTAYGTELADGKVIAEFDGRPYVQERWLKADFALVKAHL
GDSHGNLTYRMAARNFNPLMCMAAAKTIVQVSRIVPLGGIEPENVITPGIFVDRVVEIANPQQEEELIRAGVAYI

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG1788

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit A family [H]

Homologues:

Organism=Homo sapiens, GI4557817, Length=226, Percent_Identity=44.2477876106195, Blast_Score=194, Evalue=4e-50,
Organism=Homo sapiens, GI11545841, Length=233, Percent_Identity=45.0643776824034, Blast_Score=181, Evalue=4e-46,
Organism=Escherichia coli, GI1788551, Length=216, Percent_Identity=41.2037037037037, Blast_Score=174, Evalue=5e-45,
Organism=Escherichia coli, GI1787985, Length=246, Percent_Identity=28.4552845528455, Blast_Score=65, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17531517, Length=234, Percent_Identity=43.5897435897436, Blast_Score=186, Evalue=1e-47,
Organism=Drosophila melanogaster, GI21358325, Length=245, Percent_Identity=42.8571428571429, Blast_Score=190, Evalue=7e-49,
Organism=Drosophila melanogaster, GI24655794, Length=245, Percent_Identity=42.8571428571429, Blast_Score=190, Evalue=8e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012792
- InterPro:   IPR004165
- InterPro:   IPR004163 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: =2.8.3.6 [H]

Molecular weight: Translated: 24919; Mature: 24919

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: PS01273 COA_TRANSF_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKTIGSAAEAVAEIGDGATVMIGGFGGSGAPIELIHALIDKGSKGLTVINNNAGNGRIG
CCCCHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCEEE
IAAMIDAGMVRKMICSFPRSSDPRAFTDRYLAGEIELELVPQGTLAERMRAGGAGIPAFY
EHHHHHHHHHHHHHHHCCCCCCCCHHHHHEEECEEEEEEECCCHHHHHHHCCCCCCCCEE
TPTAYGTELADGKVIAEFDGRPYVQERWLKADFALVKAHLGDSHGNLTYRMAARNFNPLM
CCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHH
CMAAAKTIVQVSRIVPLGGIEPENVITPGIFVDRVVEIANPQQEEELIRAGVAYI
HHHHHHHHHHHHHHCCCCCCCCCCEECCCHHHHHHHHHCCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MDKTIGSAAEAVAEIGDGATVMIGGFGGSGAPIELIHALIDKGSKGLTVINNNAGNGRIG
CCCCHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCEEE
IAAMIDAGMVRKMICSFPRSSDPRAFTDRYLAGEIELELVPQGTLAERMRAGGAGIPAFY
EHHHHHHHHHHHHHHHCCCCCCCCHHHHHEEECEEEEEEECCCHHHHHHHCCCCCCCCEE
TPTAYGTELADGKVIAEFDGRPYVQERWLKADFALVKAHLGDSHGNLTYRMAARNFNPLM
CCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHH
CMAAAKTIVQVSRIVPLGGIEPENVITPGIFVDRVVEIANPQQEEELIRAGVAYI
HHHHHHHHHHHHHHCCCCCCCCCCEECCCHHHHHHHHHCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1624453; 6780551 [H]