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The map label for this gene is hdeA

Identifier: 225686178

GI number: 225686178

Start: 321575

End: 321919

Strand: Direct

Name: hdeA

Synonym: BMEA_B0341

Alternate gene names: 225686178

Gene position: 321575-321919 (Clockwise)

Preceding gene: 225686177

Following gene: 225686179

Centisome position: 27.13

GC content: 49.28

Gene sequence:

>345_bases
ATGATTAAGGCTCTCTTCAATAAGAATACTGCTCTTGCAGCCGTTGCCATTCTTGCTTTGTCGGGTGGTGCAATGGCAGA
GAGCGCCAAGACCCATAAGACTGATATGGCAAAGAAGAAGGTGAGTGAACTCACCTGCGAAGACTTCAACGGGCTGGAAG
AAAGCTTCAAGCCGACGGTCGTGGGTTGGGTCGTAGGCTTTAACAAGAAGGGCAAAGAAGAAGATGCCGTCATCGACGTT
GATGGTATCGAAACCGTAACCCCTGCCATCATCGAAGCCTGCAAGCAGGAGCCGAAAGCATCGTTCTGGAAAAAGGCTGA
AGCAGAACTCAAGAAAGTTTTCTGA

Upstream 100 bases:

>100_bases
TTATATAAAAACTATGTATATTAGAGGATTGTCATGGACAATCCTTGTAGGATAATATAGAAATGAGACGTGTTACTATA
TCTAAGCGAAGGAGAAGGAA

Downstream 100 bases:

>100_bases
TCCTTCGCCGCTGCCTATCTCTCCCTCCCGAGGCAGCGGGCGGCTCCGGGGCTTTGTCTCCGGAGCCGCTATTCCATGAA
TGGATAGGCGATGGGCATGT

Product: acid-resistance protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 114; Mature: 114

Protein sequence:

>114_residues
MIKALFNKNTALAAVAILALSGGAMAESAKTHKTDMAKKKVSELTCEDFNGLEESFKPTVVGWVVGFNKKGKEEDAVIDV
DGIETVTPAIIEACKQEPKASFWKKAEAELKKVF

Sequences:

>Translated_114_residues
MIKALFNKNTALAAVAILALSGGAMAESAKTHKTDMAKKKVSELTCEDFNGLEESFKPTVVGWVVGFNKKGKEEDAVIDV
DGIETVTPAIIEACKQEPKASFWKKAEAELKKVF
>Mature_114_residues
MIKALFNKNTALAAVAILALSGGAMAESAKTHKTDMAKKKVSELTCEDFNGLEESFKPTVVGWVVGFNKKGKEEDAVIDV
DGIETVTPAIIEACKQEPKASFWKKAEAELKKVF

Specific function: Exhibits a chaperone-like activity only at pH below 3 by suppressing non-specifically the aggregation of denaturated periplasmic proteins. Also promotes the solubilization at neutral pH of proteins that had aggregated in their presence at acidic pHs. Cont

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hdeA family

Homologues:

Organism=Escherichia coli, GI1789926, Length=88, Percent_Identity=47.7272727272727, Blast_Score=83, Evalue=4e-18,

Paralogues:

None

Copy number: 8460 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1060 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5460 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 1020 Molecules/Cell In: Early St

Swissprot (AC and ID): HDEA_BRUA2 (Q2YK18)

Other databases:

- EMBL:   AM040265
- RefSeq:   YP_419016.1
- ProteinModelPortal:   Q2YK18
- SMR:   Q2YK18
- STRING:   Q2YK18
- GeneID:   3828246
- GenomeReviews:   AM040265_GR
- KEGG:   bmf:BAB2_0862
- eggNOG:   NOG149939
- HOGENOM:   HBG518163
- OMA:   WATAYSK
- ProtClustDB:   PRK10208
- BioCyc:   BMEL359391:BAB2_0862-MONOMER
- InterPro:   IPR010486
- Gene3D:   G3DSA:1.10.890.10
- PIRSF:   PIRSF009564
- ProDom:   PD065392

Pfam domain/function: PF06411 HdeA; SSF47752 HNS-dep_expression_A

EC number: NA

Molecular weight: Translated: 12332; Mature: 12332

Theoretical pI: Translated: 7.27; Mature: 7.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKALFNKNTALAAVAILALSGGAMAESAKTHKTDMAKKKVSELTCEDFNGLEESFKPTV
CCCCHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCHHHHCCHHHHCCCEE
VGWVVGFNKKGKEEDAVIDVDGIETVTPAIIEACKQEPKASFWKKAEAELKKVF
EEEEECCCCCCCCCCCEEECCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIKALFNKNTALAAVAILALSGGAMAESAKTHKTDMAKKKVSELTCEDFNGLEESFKPTV
CCCCHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCHHHHCCHHHHCCCEE
VGWVVGFNKKGKEEDAVIDVDGIETVTPAIIEACKQEPKASFWKKAEAELKKVF
EEEEECCCCCCCCCCCEEECCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA