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The map label for this gene is nrdF [H]

Identifier: 225686158

GI number: 225686158

Start: 300394

End: 301383

Strand: Direct

Name: nrdF [H]

Synonym: BMEA_B0317

Alternate gene names: 225686158

Gene position: 300394-301383 (Clockwise)

Preceding gene: 225686157

Following gene: 225686160

Centisome position: 25.34

GC content: 51.72

Gene sequence:

>990_bases
ATGAATATGCAACATAAAACCGCGACCAAAGGCAGGCCCGCTTCCGTGCGCGCCATCAACTGGAACCGCATCGAGGATGA
TAAGGATCTGGAAGTCTGGAACCGGCTCACAGGCAATTTCTGGCTGCCGGAAAAAGTGCCGCTTTCCAACGACATCCAAT
CGTGGGAAACGCTGAAACCGCAGGAAAAGCAATTGACGACCCGTGTTTTTACCGGGTTGACGCTTCTCGATACGATCCAG
AATGCGGTGGGTGCGGTGAAGCTGATGGACGATGCGCTGACACCGCATGAGGAAGCCGTGCTTTCCAATATTTCCTTCAT
GGAAGCCGTGCATGCGCGGTCATATTCGTCTATTTTTTCAACGCTTTGCCTGACGCCGGACGTGGACGATGCCTATCGCT
GGTCGGAGGAAAACGAATTCCTGCAAAGAAAATCCACTTTGATCCTCGACCAGTATCACGCAGACGATCCCTTGAAAAAG
AAGATCGCCAGCGTGTTTCTGGAAAGCTTCCTGTTCTATTCGGGCTTCTATCTGCCGATGTATTGGTCAAGCAGGGCAAA
GCTTACCAACACGGCCGATCTCATCCGCCTTATCATCCGCGATGAAGCCGTGCATGGCTATTATATCGGATATAAGTTCC
AGCGTGCGCTGGAGGTTCTGTCCGAGGAGAAAAGGCAGGAAATAAAGGATTTCGCCTTTGAGCTTCTGCTGGAACTCTAT
GACAATGAGGTGCGCTATACCGAGGCTCTCTACGATGGCGTGGGGCTGACGGAGGACGTCAAAAAATTCCTGCATTACAA
TGCCAACAAGGCGCTTATGAACCTTGGATATGAGGCGCTTTTCCCGGCTGAAGCCTGCAAGGTCAACCCGGCGATCCTTT
CGGCACTTTCACCGAATGCTGATGAAAATCATGATTTCTTCTCAGGCTCCGGTTCATCCTATGTGATAGGCAAGGCGGTC
GCCACGGAAGACGAAGACTGGGCTTTCTGA

Upstream 100 bases:

>100_bases
GCATCAAGACCATCTACTACATTCGCCTGCGCCAGATGGCGCTTGAAGGAACGCAGGTGCAAGGCTGCGTTTCCTGCGCG
CTGTGACCGAGGAAAGTTTC

Downstream 100 bases:

>100_bases
TCCCGCTTCGATGCGTCGGATTATGCTCTAAAATAAGAACCGCCTCGCGATTGGGCGGGGGCTTGCTTGGGGCGCGAGGC
GGGCGGGCCATTGGAGAATG

Product: ribonucleotide-diphosphate reductase subunit beta

Products: NA

Alternate protein names: Ribonucleotide reductase small subunit [H]

Number of amino acids: Translated: 329; Mature: 329

Protein sequence:

>329_residues
MNMQHKTATKGRPASVRAINWNRIEDDKDLEVWNRLTGNFWLPEKVPLSNDIQSWETLKPQEKQLTTRVFTGLTLLDTIQ
NAVGAVKLMDDALTPHEEAVLSNISFMEAVHARSYSSIFSTLCLTPDVDDAYRWSEENEFLQRKSTLILDQYHADDPLKK
KIASVFLESFLFYSGFYLPMYWSSRAKLTNTADLIRLIIRDEAVHGYYIGYKFQRALEVLSEEKRQEIKDFAFELLLELY
DNEVRYTEALYDGVGLTEDVKKFLHYNANKALMNLGYEALFPAEACKVNPAILSALSPNADENHDFFSGSGSSYVIGKAV
ATEDEDWAF

Sequences:

>Translated_329_residues
MNMQHKTATKGRPASVRAINWNRIEDDKDLEVWNRLTGNFWLPEKVPLSNDIQSWETLKPQEKQLTTRVFTGLTLLDTIQ
NAVGAVKLMDDALTPHEEAVLSNISFMEAVHARSYSSIFSTLCLTPDVDDAYRWSEENEFLQRKSTLILDQYHADDPLKK
KIASVFLESFLFYSGFYLPMYWSSRAKLTNTADLIRLIIRDEAVHGYYIGYKFQRALEVLSEEKRQEIKDFAFELLLELY
DNEVRYTEALYDGVGLTEDVKKFLHYNANKALMNLGYEALFPAEACKVNPAILSALSPNADENHDFFSGSGSSYVIGKAV
ATEDEDWAF
>Mature_329_residues
MNMQHKTATKGRPASVRAINWNRIEDDKDLEVWNRLTGNFWLPEKVPLSNDIQSWETLKPQEKQLTTRVFTGLTLLDTIQ
NAVGAVKLMDDALTPHEEAVLSNISFMEAVHARSYSSIFSTLCLTPDVDDAYRWSEENEFLQRKSTLILDQYHADDPLKK
KIASVFLESFLFYSGFYLPMYWSSRAKLTNTADLIRLIIRDEAVHGYYIGYKFQRALEVLSEEKRQEIKDFAFELLLELY
DNEVRYTEALYDGVGLTEDVKKFLHYNANKALMNLGYEALFPAEACKVNPAILSALSPNADENHDFFSGSGSSYVIGKAV
ATEDEDWAF

Specific function: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides [H]

COG id: COG0208

COG function: function code F; Ribonucleotide reductase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribonucleoside diphosphate reductase small chain family [H]

Homologues:

Organism=Homo sapiens, GI4557845, Length=268, Percent_Identity=23.8805970149254, Blast_Score=66, Evalue=6e-11,
Organism=Homo sapiens, GI260064013, Length=268, Percent_Identity=23.8805970149254, Blast_Score=66, Evalue=6e-11,
Organism=Homo sapiens, GI289177074, Length=260, Percent_Identity=23.8461538461538, Blast_Score=65, Evalue=9e-11,
Organism=Escherichia coli, GI1789031, Length=316, Percent_Identity=77.2151898734177, Blast_Score=504, Evalue=1e-144,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009078
- InterPro:   IPR012348
- InterPro:   IPR000358 [H]

Pfam domain/function: PF00268 Ribonuc_red_sm [H]

EC number: =1.17.4.1 [H]

Molecular weight: Translated: 37677; Mature: 37677

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: PS00368 RIBORED_SMALL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNMQHKTATKGRPASVRAINWNRIEDDKDLEVWNRLTGNFWLPEKVPLSNDIQSWETLKP
CCCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCHHHHHHCCC
QEKQLTTRVFTGLTLLDTIQNAVGAVKLMDDALTPHEEAVLSNISFMEAVHARSYSSIFS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
TLCLTPDVDDAYRWSEENEFLQRKSTLILDQYHADDPLKKKIASVFLESFLFYSGFYLPM
HHHCCCCCCHHHHCCCHHHHHHHHHHHEEEHHCCCCHHHHHHHHHHHHHHHHHCCCCEEE
YWSSRAKLTNTADLIRLIIRDEAVHGYYIGYKFQRALEVLSEEKRQEIKDFAFELLLELY
EECCCCCCCHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DNEVRYTEALYDGVGLTEDVKKFLHYNANKALMNLGYEALFPAEACKVNPAILSALSPNA
CCCHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHCCHHHHCCHHHHCCCHHHHHHCCCCC
DENHDFFSGSGSSYVIGKAVATEDEDWAF
CCCCCCCCCCCCCEEEEEEEECCCCCCCC
>Mature Secondary Structure
MNMQHKTATKGRPASVRAINWNRIEDDKDLEVWNRLTGNFWLPEKVPLSNDIQSWETLKP
CCCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCHHHHHHCCC
QEKQLTTRVFTGLTLLDTIQNAVGAVKLMDDALTPHEEAVLSNISFMEAVHARSYSSIFS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
TLCLTPDVDDAYRWSEENEFLQRKSTLILDQYHADDPLKKKIASVFLESFLFYSGFYLPM
HHHCCCCCCHHHHCCCHHHHHHHHHHHEEEHHCCCCHHHHHHHHHHHHHHHHHCCCCEEE
YWSSRAKLTNTADLIRLIIRDEAVHGYYIGYKFQRALEVLSEEKRQEIKDFAFELLLELY
EECCCCCCCHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DNEVRYTEALYDGVGLTEDVKKFLHYNANKALMNLGYEALFPAEACKVNPAILSALSPNA
CCCHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHCCHHHHCCHHHHCCCHHHHHHCCCCC
DENHDFFSGSGSSYVIGKAVATEDEDWAF
CCCCCCCCCCCCCEEEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]