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The map label for this gene is malE [C]

Identifier: 225686148

GI number: 225686148

Start: 288180

End: 289445

Strand: Direct

Name: malE [C]

Synonym: BMEA_B0304

Alternate gene names: 225686148

Gene position: 288180-289445 (Clockwise)

Preceding gene: 225686146

Following gene: 225686149

Centisome position: 24.31

GC content: 57.82

Gene sequence:

>1266_bases
ATGAGGGTTTTGACAGGAGCACTGGTTGCTTGCGCTGCGTTCGGCTTTGCTACCGGATGGGCGCAGGCGGTGGAAATTTC
GATTGCGGCCAATTCCACCGGCGACAATATCAAGTTTCTTCAGGAACAGGTTGCCAAATTCGAGAAGGATACCGGCAACA
AGGTCAATATCATCTCGATGCCGTCATCGAGCAGCGAGCAGTTCAGCCAGTATCGCCTGTGGCTGGCCGCGGGCAATTCG
GATGTGGATGTCTATCAGACCGACATTGTCTGGGCGCCGCAGTTGTCGGACCAGTTCATCGACCTCACGGAAGCGACAAA
GGATGTGACGGACGCGCATTTTCCCTCGATCATCGCGTCCCAGACGGTGAACGGCAAGCTTGTGGCGCTGCCTTTCTATA
CGGATGCTCCGGCGCTGTTCTGTCGCAAGGATTTACTTGAAAAATATAACAAGCCTGTTCCCAAAACCTGGGATGAAATG
GCTGCCACCGCCAAGGACATCATGGAAAAGGAGCGTGCCGACGGCAAGGCTGATCTCTGGGGCTTTGTCTTTCAGGGCAA
TGCCTATGAGGGGCTGACCTGCAATGCGCTGGAGTGGATCAAGTCTTCCGGCGGCGGGCAGATCGTCGAGCCTGACGGTG
AAATTTCGGTCAATAATGAGAAGGCCGCTGCGGCGATCGACCGTGCCAGGGGCTGGATCGGCACGATCTCGCCGCAGGGC
GTGCTTGGCTATCAGGAAGAGGAATTGCGCGGCGTCTGGCAGACCGGCAATGCCGTTTTCATGCGCAACTGGCCCTATGT
CTATGCACTCAGCAACAGCGCGGATAGCGCCGTCAAGGGCAAGTTCGACGTTGCTCCGCTTCCCGCCATGGCCGAAGGCG
AGCCACCTGCATCGGCACTCGGCGGCTGGAACCTTGCCGTTTCCAAATATTCCACCAAGCAGGATGCGGCCATCGCGCTG
GTGAAATTCCTGGCCTCGCCAGAGGTGCAGAAGGCGGAAGCCGTGGAGCTTTCACGTCTTCCGACCATAGAGGCGCTCTA
TGACGACAAGGACGTGATCGCTGCCCAGCCGTTCATGGCCAACTGGAAGCCGATTTTCCAGAATGCCGTACCGCGCCCTT
CGGCGGCGACCAAGGTGAAATATAACGAGGTTTCCTCGAAGTTCTGGACCGCCGTGCACAAGACCTTGGCAGGCAGCGGT
ACTGCGGCGGAAAACCTTGAACTGCTTGAGGTCGAGCTGACCGAGCTTAAAGGCTCGGGCTGGTAG

Upstream 100 bases:

>100_bases
AGGGCGGCTGTCTGTAACCTTCCTCTACCCAAACCGTTTTCGATTTTGATAAGCTATCTGATTTTTACATGTTTATAAAA
TAGATGGGAGGAGGGAAATC

Downstream 100 bases:

>100_bases
AGCTGATCGAGCCGCGTTCGGGCTTTTCCCCAAGCGGCCCGAACGCCCTTCTCATCCGATGACCCGGAGCAGGATCATGA
CGGAGACTTCCCTTGATGCG

Product: family 1 extracellular solute-binding protein

Products: ADP; phosphate; maltose [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 421; Mature: 421

Protein sequence:

>421_residues
MRVLTGALVACAAFGFATGWAQAVEISIAANSTGDNIKFLQEQVAKFEKDTGNKVNIISMPSSSSEQFSQYRLWLAAGNS
DVDVYQTDIVWAPQLSDQFIDLTEATKDVTDAHFPSIIASQTVNGKLVALPFYTDAPALFCRKDLLEKYNKPVPKTWDEM
AATAKDIMEKERADGKADLWGFVFQGNAYEGLTCNALEWIKSSGGGQIVEPDGEISVNNEKAAAAIDRARGWIGTISPQG
VLGYQEEELRGVWQTGNAVFMRNWPYVYALSNSADSAVKGKFDVAPLPAMAEGEPPASALGGWNLAVSKYSTKQDAAIAL
VKFLASPEVQKAEAVELSRLPTIEALYDDKDVIAAQPFMANWKPIFQNAVPRPSAATKVKYNEVSSKFWTAVHKTLAGSG
TAAENLELLEVELTELKGSGW

Sequences:

>Translated_421_residues
MRVLTGALVACAAFGFATGWAQAVEISIAANSTGDNIKFLQEQVAKFEKDTGNKVNIISMPSSSSEQFSQYRLWLAAGNS
DVDVYQTDIVWAPQLSDQFIDLTEATKDVTDAHFPSIIASQTVNGKLVALPFYTDAPALFCRKDLLEKYNKPVPKTWDEM
AATAKDIMEKERADGKADLWGFVFQGNAYEGLTCNALEWIKSSGGGQIVEPDGEISVNNEKAAAAIDRARGWIGTISPQG
VLGYQEEELRGVWQTGNAVFMRNWPYVYALSNSADSAVKGKFDVAPLPAMAEGEPPASALGGWNLAVSKYSTKQDAAIAL
VKFLASPEVQKAEAVELSRLPTIEALYDDKDVIAAQPFMANWKPIFQNAVPRPSAATKVKYNEVSSKFWTAVHKTLAGSG
TAAENLELLEVELTELKGSGW
>Mature_421_residues
MRVLTGALVACAAFGFATGWAQAVEISIAANSTGDNIKFLQEQVAKFEKDTGNKVNIISMPSSSSEQFSQYRLWLAAGNS
DVDVYQTDIVWAPQLSDQFIDLTEATKDVTDAHFPSIIASQTVNGKLVALPFYTDAPALFCRKDLLEKYNKPVPKTWDEM
AATAKDIMEKERADGKADLWGFVFQGNAYEGLTCNALEWIKSSGGGQIVEPDGEISVNNEKAAAAIDRARGWIGTISPQG
VLGYQEEELRGVWQTGNAVFMRNWPYVYALSNSADSAVKGKFDVAPLPAMAEGEPPASALGGWNLAVSKYSTKQDAAIAL
VKFLASPEVQKAEAVELSRLPTIEALYDDKDVIAAQPFMANWKPIFQNAVPRPSAATKVKYNEVSSKFWTAVHKTLAGSG
TAAENLELLEVELTELKGSGW

Specific function: Probably part of a binding-protein-dependent transport system [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 1 family [H]

Homologues:

None

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 720 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 240 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase,

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006059 [H]

Pfam domain/function: PF01547 SBP_bac_1 [H]

EC number: NA

Molecular weight: Translated: 45681; Mature: 45681

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVLTGALVACAAFGFATGWAQAVEISIAANSTGDNIKFLQEQVAKFEKDTGNKVNIISM
CCCHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHCCCCEEEEEEC
PSSSSEQFSQYRLWLAAGNSDVDVYQTDIVWAPQLSDQFIDLTEATKDVTDAHFPSIIAS
CCCCHHHHHHEEEEEEECCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCHHHHH
QTVNGKLVALPFYTDAPALFCRKDLLEKYNKPVPKTWDEMAATAKDIMEKERADGKADLW
CCCCCEEEEEEEECCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEE
GFVFQGNAYEGLTCNALEWIKSSGGGQIVEPDGEISVNNEKAAAAIDRARGWIGTISPQG
EEEEECCCCCCCCHHHHHHHHCCCCCEEECCCCCEEECCCHHHHHHHHHCCCEECCCCCC
VLGYQEEELRGVWQTGNAVFMRNWPYVYALSNSADSAVKGKFDVAPLPAMAEGEPPASAL
CCCCCHHHHHHHHCCCCEEEEECCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHH
GGWNLAVSKYSTKQDAAIALVKFLASPEVQKAEAVELSRLPTIEALYDDKDVIAAQPFMA
CCCEEEEECCCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHCCCCCCEECCCCCC
NWKPIFQNAVPRPSAATKVKYNEVSSKFWTAVHKTLAGSGTAAENLELLEVELTELKGSG
CCHHHHHCCCCCCCCCCEEEHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEECCCCC
W
C
>Mature Secondary Structure
MRVLTGALVACAAFGFATGWAQAVEISIAANSTGDNIKFLQEQVAKFEKDTGNKVNIISM
CCCHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHCCCCEEEEEEC
PSSSSEQFSQYRLWLAAGNSDVDVYQTDIVWAPQLSDQFIDLTEATKDVTDAHFPSIIAS
CCCCHHHHHHEEEEEEECCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCHHHHH
QTVNGKLVALPFYTDAPALFCRKDLLEKYNKPVPKTWDEMAATAKDIMEKERADGKADLW
CCCCCEEEEEEEECCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEE
GFVFQGNAYEGLTCNALEWIKSSGGGQIVEPDGEISVNNEKAAAAIDRARGWIGTISPQG
EEEEECCCCCCCCHHHHHHHHCCCCCEEECCCCCEEECCCHHHHHHHHHCCCEECCCCCC
VLGYQEEELRGVWQTGNAVFMRNWPYVYALSNSADSAVKGKFDVAPLPAMAEGEPPASAL
CCCCCHHHHHHHHCCCCEEEEECCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHH
GGWNLAVSKYSTKQDAAIALVKFLASPEVQKAEAVELSRLPTIEALYDDKDVIAAQPFMA
CCCEEEEECCCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHCCCCCCEECCCCCC
NWKPIFQNAVPRPSAATKVKYNEVSSKFWTAVHKTLAGSGTAAENLELLEVELTELKGSG
CCHHHHHCCCCCCCCCCEEEHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEECCCCC
W
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; maltose [Periplasm]; H2O [C]

Specific reaction: ATP + maltose [Periplasm] + H2O = ADP + phosphate + maltose [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10567266 [H]