Click here to switch to the map view.

The map label for this gene is lolC [H]

Identifier: 225630889

GI number: 225630889

Start: 1295163

End: 1296392

Strand: Direct

Name: lolC [H]

Synonym: WRi_012040

Alternate gene names: 225630889

Gene position: 1295163-1296392 (Clockwise)

Preceding gene: 225630888

Following gene: 225630890

Centisome position: 89.58

GC content: 34.96

Gene sequence:

>1230_bases
ATGTCCATTGCCTTTGAAATTACTATGGCTGCTTGCTATTTGCGAGCGAAAAATGCCAGATTTTGCTCTATAATGACTTT
GTTCTCTATTATCGGCATTGCCCTTGGAGTTGCAACACTAATAGTGGTGATGTCTGTGATGAACGGATTCAGAGCAAAGT
TGCTTGACTCAATACTTGGCATTGATGGCCATATTAATGTTTATTTTGATAGGAACATAAATTCAGATTACTACGCAGTT
TCAAAATCTATTGAGAGAATTCCTGGTATATTAAAAGCTACTCCTATGACCAATGATCAAGTTATTATTGTAGCAAACGG
TAAAATTGCAGGTAGCGTAGTGCGAGGTGTATCAACTAAAGACTTGCTTGATAGTACTGCCGTTACAAATAATGTAATTA
TAGGTGATGTAAAAAAATTTGATGAAGGAATAATAATAGGAGCACGCTTAGCAGAAGCTTTGAACGTTGACTATGGCGAC
GAAATTACGTTTATATCATCTGAAGAATTTGATGCATTACTTGGTGAAATGCCGCGAATGAAAAAATATAAAGTTATAGC
AATATTTGATATGGGTATGTTTGAGTATGATAATACCTTGATATATATGCCTCTAAAATCAGCACAAGCCTTTTTTAATT
ATAAAAATAGCATAAAAAATATAGAAGTACTTGTAGACGACGTTACTAGAGCTGATAAGCTGGCAGATGCTATAGAAAAA
GAAATAGGAATGGAAGCTGAAAGTTGGCAATCACAGCAAAGCCATTATTTTAGTGCTTTAAAAACTGAAAGAAATGTGAT
GTTTTTAATTCTCACTTTGATTATAGTTGTAGCAGCGTTTAATATTATCTCAAATTTAATGATGATAGTGCAAGAAAAGA
AATCCGCGATTGCAATTATGCGTACATTTGGTGCAACAAGTGGAAGCATTATGCGTATATTTTGCGCTTGTGGTCTATTA
ATCGGTTTTACGGGAACTTGTCTTGGCTGTATTATAGGTGTCGTTTTTTCTCTCAATATCGAAAGCATTAGAGTGTTTTT
AGAAAACATTACTAACGTCAAGCTGTTTGATCCTATGATATACTTTTTTTCAAGTTTGCCAGTGATATTAGTACCCCAAG
ACGTAGTAAATATTTCTGCACTTGCGTTACTCTTATCATTTTTAGCGACAATTGCTCCTGCGTTGCAGGCAGCTGCACAA
GATCCTGCGGAGATACTACGTTATGAATGA

Upstream 100 bases:

>100_bases
TAAATTTAAGGAAGCAAAAATCTCTAGTTTTCAAATAAAGAAAAGTCTACAATTATACGAAGTTTCAAAAATATAATGTT
TAACCTCAAAATATTTTGTA

Downstream 100 bases:

>100_bases
TACTCAGCAAAAGTACATAGGTTGGTTCTTAATTGTATTGTTATTTACCGGTTACATCACAATAAATAACATAATCTTTT
TAAAAATAAATCAGCAAGAG

Product: lipoprotein releasing system transmembrane protein lolc

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 409; Mature: 408

Protein sequence:

>409_residues
MSIAFEITMAACYLRAKNARFCSIMTLFSIIGIALGVATLIVVMSVMNGFRAKLLDSILGIDGHINVYFDRNINSDYYAV
SKSIERIPGILKATPMTNDQVIIVANGKIAGSVVRGVSTKDLLDSTAVTNNVIIGDVKKFDEGIIIGARLAEALNVDYGD
EITFISSEEFDALLGEMPRMKKYKVIAIFDMGMFEYDNTLIYMPLKSAQAFFNYKNSIKNIEVLVDDVTRADKLADAIEK
EIGMEAESWQSQQSHYFSALKTERNVMFLILTLIIVVAAFNIISNLMMIVQEKKSAIAIMRTFGATSGSIMRIFCACGLL
IGFTGTCLGCIIGVVFSLNIESIRVFLENITNVKLFDPMIYFFSSLPVILVPQDVVNISALALLLSFLATIAPALQAAAQ
DPAEILRYE

Sequences:

>Translated_409_residues
MSIAFEITMAACYLRAKNARFCSIMTLFSIIGIALGVATLIVVMSVMNGFRAKLLDSILGIDGHINVYFDRNINSDYYAV
SKSIERIPGILKATPMTNDQVIIVANGKIAGSVVRGVSTKDLLDSTAVTNNVIIGDVKKFDEGIIIGARLAEALNVDYGD
EITFISSEEFDALLGEMPRMKKYKVIAIFDMGMFEYDNTLIYMPLKSAQAFFNYKNSIKNIEVLVDDVTRADKLADAIEK
EIGMEAESWQSQQSHYFSALKTERNVMFLILTLIIVVAAFNIISNLMMIVQEKKSAIAIMRTFGATSGSIMRIFCACGLL
IGFTGTCLGCIIGVVFSLNIESIRVFLENITNVKLFDPMIYFFSSLPVILVPQDVVNISALALLLSFLATIAPALQAAAQ
DPAEILRYE
>Mature_408_residues
SIAFEITMAACYLRAKNARFCSIMTLFSIIGIALGVATLIVVMSVMNGFRAKLLDSILGIDGHINVYFDRNINSDYYAVS
KSIERIPGILKATPMTNDQVIIVANGKIAGSVVRGVSTKDLLDSTAVTNNVIIGDVKKFDEGIIIGARLAEALNVDYGDE
ITFISSEEFDALLGEMPRMKKYKVIAIFDMGMFEYDNTLIYMPLKSAQAFFNYKNSIKNIEVLVDDVTRADKLADAIEKE
IGMEAESWQSQQSHYFSALKTERNVMFLILTLIIVVAAFNIISNLMMIVQEKKSAIAIMRTFGATSGSIMRIFCACGLLI
GFTGTCLGCIIGVVFSLNIESIRVFLENITNVKLFDPMIYFFSSLPVILVPQDVVNISALALLLSFLATIAPALQAAAQD
PAEILRYE

Specific function: Part of an ATP-dependent transport system responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787362, Length=393, Percent_Identity=32.824427480916, Blast_Score=165, Evalue=4e-42,
Organism=Escherichia coli, GI1787360, Length=403, Percent_Identity=28.7841191066998, Blast_Score=157, Evalue=2e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838
- InterPro:   IPR011925 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 44982; Mature: 44850

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIAFEITMAACYLRAKNARFCSIMTLFSIIGIALGVATLIVVMSVMNGFRAKLLDSILG
CCEEEEHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
IDGHINVYFDRNINSDYYAVSKSIERIPGILKATPMTNDQVIIVANGKIAGSVVRGVSTK
CCCEEEEEEECCCCCCHHHHHHHHHHCCCCEEECCCCCCCEEEEECCCCHHHHHHCCCHH
DLLDSTAVTNNVIIGDVKKFDEGIIIGARLAEALNVDYGDEITFISSEEFDALLGEMPRM
HHHHHHHHCCCEEEECHHHHCCCEEEHHHHHHHHCCCCCCCEEEECCHHHHHHHHCCCCC
KKYKVIAIFDMGMFEYDNTLIYMPLKSAQAFFNYKNSIKNIEVLVDDVTRADKLADAIEK
CCEEEEEEEECCEEEECCEEEEEECHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
EIGMEAESWQSQQSHYFSALKTERNVMFLILTLIIVVAAFNIISNLMMIVQEKKSAIAIM
HHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RTFGATSGSIMRIFCACGLLIGFTGTCLGCIIGVVFSLNIESIRVFLENITNVKLFDPMI
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHH
YFFSSLPVILVPQDVVNISALALLLSFLATIAPALQAAAQDPAEILRYE
HHHCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCC
>Mature Secondary Structure 
SIAFEITMAACYLRAKNARFCSIMTLFSIIGIALGVATLIVVMSVMNGFRAKLLDSILG
CEEEEHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
IDGHINVYFDRNINSDYYAVSKSIERIPGILKATPMTNDQVIIVANGKIAGSVVRGVSTK
CCCEEEEEEECCCCCCHHHHHHHHHHCCCCEEECCCCCCCEEEEECCCCHHHHHHCCCHH
DLLDSTAVTNNVIIGDVKKFDEGIIIGARLAEALNVDYGDEITFISSEEFDALLGEMPRM
HHHHHHHHCCCEEEECHHHHCCCEEEHHHHHHHHCCCCCCCEEEECCHHHHHHHHCCCCC
KKYKVIAIFDMGMFEYDNTLIYMPLKSAQAFFNYKNSIKNIEVLVDDVTRADKLADAIEK
CCEEEEEEEECCEEEECCEEEEEECHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
EIGMEAESWQSQQSHYFSALKTERNVMFLILTLIIVVAAFNIISNLMMIVQEKKSAIAIM
HHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RTFGATSGSIMRIFCACGLLIGFTGTCLGCIIGVVFSLNIESIRVFLENITNVKLFDPMI
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHH
YFFSSLPVILVPQDVVNISALALLLSFLATIAPALQAAAQDPAEILRYE
HHHCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]