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The map label for this gene is murA [H]

Identifier: 225630863

GI number: 225630863

Start: 1262518

End: 1263795

Strand: Direct

Name: murA [H]

Synonym: WRi_011710

Alternate gene names: 225630863

Gene position: 1262518-1263795 (Clockwise)

Preceding gene: 225630862

Following gene: 225630864

Centisome position: 87.32

GC content: 36.46

Gene sequence:

>1278_bases
ATGCACAAGATATTAATAAGAAATAACTACAAACCTTTGGTCGGAAAAATCAAGATTAATGGCTCAAAAAATGCTGTTTT
ACCAATAATGGCAGCAAGTCTATTAAGTAGCTCCCCGGTAATTTTGCATAATGTGCCTGATTTAATTGATGTGCATCTAA
TGTCTAAGTTGCTTGAAAGTCTTGGAGCAGAAGTGAACTTTATGCACAATAAAAATTATAAAGCGAACCATACTTTGAAA
ATTGACTGCAGCAATATCAACAATCACGTGATGCCATATAAAACCGCAAGTAAGCTAAGAACTTCTTTTCTAATATTGGG
TCCAATGCTTAGCAGATTTGGCAAAGCGAGAACAGCATTTCCTGGTGGATGCAACATTGGAAAGCGTCCCGTTGATATGC
ATATTAAAGCATTAGAAGAAATGGGAGCTAAAATTGAAATTGACGGCTATAATATAATTGCAACAGTGAAAGGAAAGCTA
CAAGGAAAAGAAATCACATTTGAGAAAATAAGTGTTGGCGCAACAGAAAATGTAATAATGGCAGCAACATTTGCAGAAGG
AGTGACAACAATAAACAATGCTGCAACTGAGCCGGAAGTTCTTGATTTAATAGATTTTCTGAAGAAAATGGGTGCTGATA
TTGAAATTGATAATACAAAGGTCGTAATAACAGGAGTTGAAGCACTAAATGGATGTGTTCATAAAATAATACCAGATCGC
ATAGAAGCAGGCACCTATGCACTAGCTGCTATAATAACCGGTGGTAAGTTGGAGTTGGAAGGAATAAATCTATCTGATAT
AAGGTGTATTACAAATGAGTTGGAGACTATAGGAGCTATGGTTGAACTGTATGATGGAGGCATTGTTATTTCCAGAAAAA
ATGGCTCTATTAAGTCTGCTAACGTTGCGACAGATCCATATCCCAATTTTCCCAGTGATATGCAACCACAACTGATGTCT
GCAATGTGCATCGCTGATGGGATATCAGTAATTGAAGAGAACATTTTTGAAAACAGATTTACACATGCAGATGAATTGAG
AAAGTTAGGTGCTAATATCAGCATCGAGAAAAGCAAAGCTACTATAAGTGGAATAAAAAGCTTATCTGGAGCTAATCTAT
ATGCTACTGACTTAAGATCAACAGCAGCTTTGGTGCTTGCTTCTTTGGTAGCCGGTGGAGAAACTATAATAAACAATTCA
CATCATTTATGGAGAGGATATGAAGCAATGCATGAAAAACTCAATTCATGTGGAGCTGATATCTCCATTTCGTCTTGA

Upstream 100 bases:

>100_bases
GATGATGAGGAAGAAAAAGCAAATTTTGCCTTTTACGGTCAATCTATTATACTTAGTAAGACTTCAATAAACTAATGAAT
TATACTTTATATCTAATTAA

Downstream 100 bases:

>100_bases
GGATATTTTATGAATGAAGCAACCAAACGAACTATAGTAAAAGAAATAGATGCAATCTTATATGAAGAACATAAGGTATT
AGACCATGGATTTATTCGAG

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT [H]

Number of amino acids: Translated: 425; Mature: 425

Protein sequence:

>425_residues
MHKILIRNNYKPLVGKIKINGSKNAVLPIMAASLLSSSPVILHNVPDLIDVHLMSKLLESLGAEVNFMHNKNYKANHTLK
IDCSNINNHVMPYKTASKLRTSFLILGPMLSRFGKARTAFPGGCNIGKRPVDMHIKALEEMGAKIEIDGYNIIATVKGKL
QGKEITFEKISVGATENVIMAATFAEGVTTINNAATEPEVLDLIDFLKKMGADIEIDNTKVVITGVEALNGCVHKIIPDR
IEAGTYALAAIITGGKLELEGINLSDIRCITNELETIGAMVELYDGGIVISRKNGSIKSANVATDPYPNFPSDMQPQLMS
AMCIADGISVIEENIFENRFTHADELRKLGANISIEKSKATISGIKSLSGANLYATDLRSTAALVLASLVAGGETIINNS
HHLWRGYEAMHEKLNSCGADISISS

Sequences:

>Translated_425_residues
MHKILIRNNYKPLVGKIKINGSKNAVLPIMAASLLSSSPVILHNVPDLIDVHLMSKLLESLGAEVNFMHNKNYKANHTLK
IDCSNINNHVMPYKTASKLRTSFLILGPMLSRFGKARTAFPGGCNIGKRPVDMHIKALEEMGAKIEIDGYNIIATVKGKL
QGKEITFEKISVGATENVIMAATFAEGVTTINNAATEPEVLDLIDFLKKMGADIEIDNTKVVITGVEALNGCVHKIIPDR
IEAGTYALAAIITGGKLELEGINLSDIRCITNELETIGAMVELYDGGIVISRKNGSIKSANVATDPYPNFPSDMQPQLMS
AMCIADGISVIEENIFENRFTHADELRKLGANISIEKSKATISGIKSLSGANLYATDLRSTAALVLASLVAGGETIINNS
HHLWRGYEAMHEKLNSCGADISISS
>Mature_425_residues
MHKILIRNNYKPLVGKIKINGSKNAVLPIMAASLLSSSPVILHNVPDLIDVHLMSKLLESLGAEVNFMHNKNYKANHTLK
IDCSNINNHVMPYKTASKLRTSFLILGPMLSRFGKARTAFPGGCNIGKRPVDMHIKALEEMGAKIEIDGYNIIATVKGKL
QGKEITFEKISVGATENVIMAATFAEGVTTINNAATEPEVLDLIDFLKKMGADIEIDNTKVVITGVEALNGCVHKIIPDR
IEAGTYALAAIITGGKLELEGINLSDIRCITNELETIGAMVELYDGGIVISRKNGSIKSANVATDPYPNFPSDMQPQLMS
AMCIADGISVIEENIFENRFTHADELRKLGANISIEKSKATISGIKSLSGANLYATDLRSTAALVLASLVAGGETIINNS
HHLWRGYEAMHEKLNSCGADISISS

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine [H]

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789580, Length=422, Percent_Identity=41.7061611374408, Blast_Score=338, Evalue=4e-94,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.7 [H]

Molecular weight: Translated: 45869; Mature: 45869

Theoretical pI: Translated: 7.14; Mature: 7.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHKILIRNNYKPLVGKIKINGSKNAVLPIMAASLLSSSPVILHNVPDLIDVHLMSKLLES
CCEEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHH
LGAEVNFMHNKNYKANHTLKIDCSNINNHVMPYKTASKLRTSFLILGPMLSRFGKARTAF
CCCCEEEEECCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCC
PGGCNIGKRPVDMHIKALEEMGAKIEIDGYNIIATVKGKLQGKEITFEKISVGATENVIM
CCCCCCCCCCHHHHHHHHHHCCCEEEECCEEEEEEEECCCCCCEEEEEEEECCCCCCEEE
AATFAEGVTTINNAATEPEVLDLIDFLKKMGADIEIDNTKVVITGVEALNGCVHKIIPDR
EEEHHHCHHHHCCCCCCCHHHHHHHHHHHHCCCEEECCCEEEEEEHHHHHHHHHHHCCHH
IEAGTYALAAIITGGKLELEGINLSDIRCITNELETIGAMVELYDGGIVISRKNGSIKSA
HCCCCEEEEEEEECCEEEEECCCHHHHHHHHHHHHHHHHHHEEECCCEEEECCCCCCEEC
NVATDPYPNFPSDMQPQLMSAMCIADGISVIEENIFENRFTHADELRKLGANISIEKSKA
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCEEEECCHH
TISGIKSLSGANLYATDLRSTAALVLASLVAGGETIINNSHHLWRGYEAMHEKLNSCGAD
HHHHHHHCCCCCEEEHHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHHHHCCCC
ISISS
EEECC
>Mature Secondary Structure
MHKILIRNNYKPLVGKIKINGSKNAVLPIMAASLLSSSPVILHNVPDLIDVHLMSKLLES
CCEEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHH
LGAEVNFMHNKNYKANHTLKIDCSNINNHVMPYKTASKLRTSFLILGPMLSRFGKARTAF
CCCCEEEEECCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCC
PGGCNIGKRPVDMHIKALEEMGAKIEIDGYNIIATVKGKLQGKEITFEKISVGATENVIM
CCCCCCCCCCHHHHHHHHHHCCCEEEECCEEEEEEEECCCCCCEEEEEEEECCCCCCEEE
AATFAEGVTTINNAATEPEVLDLIDFLKKMGADIEIDNTKVVITGVEALNGCVHKIIPDR
EEEHHHCHHHHCCCCCCCHHHHHHHHHHHHCCCEEECCCEEEEEEHHHHHHHHHHHCCHH
IEAGTYALAAIITGGKLELEGINLSDIRCITNELETIGAMVELYDGGIVISRKNGSIKSA
HCCCCEEEEEEEECCEEEEECCCHHHHHHHHHHHHHHHHHHEEECCCEEEECCCCCCEEC
NVATDPYPNFPSDMQPQLMSAMCIADGISVIEENIFENRFTHADELRKLGANISIEKSKA
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCEEEECCHH
TISGIKSLSGANLYATDLRSTAALVLASLVAGGETIINNSHHLWRGYEAMHEKLNSCGAD
HHHHHHHCCCCCEEEHHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHHHHCCCC
ISISS
EEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA