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The map label for this gene is tlyC [H]

Identifier: 225630690

GI number: 225630690

Start: 1055156

End: 1055974

Strand: Reverse

Name: tlyC [H]

Synonym: WRi_009830

Alternate gene names: 225630690

Gene position: 1055974-1055156 (Counterclockwise)

Preceding gene: 225630694

Following gene: 225630687

Centisome position: 73.03

GC content: 30.53

Gene sequence:

>819_bases
TTGAGTAAAAAAAGAACCTTAGTAGAAAAAATAGCATATAGAATTTTTCTCTTCCTTTTCAAAAAAGCTTCTGTGTTGAA
AAAGTGTGCGACTGAGGCATTAATGAAAGATCTGCCAGACCTTAATATATTTAATGGTCTATTAAAATTCCGCGATTGTG
GTATAATGGATATAATGACTCCACGTACAGAGATATGCGCAGTAGACATTGAGTCAAGCGAGCGTGAAATAATAAAGAAG
ATAAAAAACACTTGCCACACTAAAATACCAATTTATAAAAATAACTTTGATAACGTAATAGGCTTTTTTTATGTAAAAGA
TGTTATTTTTAATAGGGATAAAAATTTTAATCTGAAACATATTATACAAAGCGTAATATTTGTTCCACCCTCGATGAAGA
CAACTAATCTTTTTGTTAGGATGAACTCTTCTAAATCATGCTTAGCTATCGTATTGGATGAATATGGTGGAACTGATGGT
TTAATTTCAATGACTGATCTTATAGAGGAACTAATACCAAACATTGATAGTGAAAACGAAATAAATTCAGAATATACCAT
TACTGAATTGTCTCAAAATAAGTTTGAAGTATCAGCAAGGGCTCTTATAAAAGATATAGAAGAGGATCTAAAAATAGAAT
TACGTGACCCTGAAGAAGACTATGTTACACTTGGTGGTTTGATTCTTTCGATTGCTGGTAAAGTGCCTTCTGTAGATGAA
GTCATTAAATATAAAAATGGTATGAAGTTTATCATCAAAGATGCAAATGAGCGCTACATTAATAAAATAGTACTAGACTT
AAGTGATTACAAAAATTAG

Upstream 100 bases:

>100_bases
ACAAATTAATTTGACATTATTCACATGCTTATTAAACATTTAATAACAGTTTTCTTGATAAATCTAATCTGAAAACGTTT
TTGCCATTACAGGGAATAAA

Downstream 100 bases:

>100_bases
ATTTGGTACCCCTTGTCGGGGAATGCCTTGACACGAAGAAAAAGTTGTAATAACCAAATATGCAACTCAAGTTATAGTTA
AACCTATTTCCAGCAAATTA

Product: CBS domain protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 272; Mature: 271

Protein sequence:

>272_residues
MSKKRTLVEKIAYRIFLFLFKKASVLKKCATEALMKDLPDLNIFNGLLKFRDCGIMDIMTPRTEICAVDIESSEREIIKK
IKNTCHTKIPIYKNNFDNVIGFFYVKDVIFNRDKNFNLKHIIQSVIFVPPSMKTTNLFVRMNSSKSCLAIVLDEYGGTDG
LISMTDLIEELIPNIDSENEINSEYTITELSQNKFEVSARALIKDIEEDLKIELRDPEEDYVTLGGLILSIAGKVPSVDE
VIKYKNGMKFIIKDANERYINKIVLDLSDYKN

Sequences:

>Translated_272_residues
MSKKRTLVEKIAYRIFLFLFKKASVLKKCATEALMKDLPDLNIFNGLLKFRDCGIMDIMTPRTEICAVDIESSEREIIKK
IKNTCHTKIPIYKNNFDNVIGFFYVKDVIFNRDKNFNLKHIIQSVIFVPPSMKTTNLFVRMNSSKSCLAIVLDEYGGTDG
LISMTDLIEELIPNIDSENEINSEYTITELSQNKFEVSARALIKDIEEDLKIELRDPEEDYVTLGGLILSIAGKVPSVDE
VIKYKNGMKFIIKDANERYINKIVLDLSDYKN
>Mature_271_residues
SKKRTLVEKIAYRIFLFLFKKASVLKKCATEALMKDLPDLNIFNGLLKFRDCGIMDIMTPRTEICAVDIESSEREIIKKI
KNTCHTKIPIYKNNFDNVIGFFYVKDVIFNRDKNFNLKHIIQSVIFVPPSMKTTNLFVRMNSSKSCLAIVLDEYGGTDGL
ISMTDLIEELIPNIDSENEINSEYTITELSQNKFEVSARALIKDIEEDLKIELRDPEEDYVTLGGLILSIAGKVPSVDEV
IKYKNGMKFIIKDANERYINKIVLDLSDYKN

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=192, Percent_Identity=27.0833333333333, Blast_Score=89, Evalue=6e-18,
Organism=Escherichia coli, GI1786879, Length=231, Percent_Identity=25.974025974026, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI145693175, Length=185, Percent_Identity=23.7837837837838, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1788119, Length=226, Percent_Identity=23.4513274336283, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI87082033, Length=227, Percent_Identity=20.704845814978, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1790664, Length=217, Percent_Identity=22.1198156682028, Blast_Score=68, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC [H]

EC number: NA

Molecular weight: Translated: 31219; Mature: 31088

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKKRTLVEKIAYRIFLFLFKKASVLKKCATEALMKDLPDLNIFNGLLKFRDCGIMDIMT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEECC
PRTEICAVDIESSEREIIKKIKNTCHTKIPIYKNNFDNVIGFFYVKDVIFNRDKNFNLKH
CCCEEEEEECCCCHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHHCCCCCCCHHH
IIQSVIFVPPSMKTTNLFVRMNSSKSCLAIVLDEYGGTDGLISMTDLIEELIPNIDSENE
HHHHHHHCCCCCCEEEEEEEECCCCCEEEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCC
INSEYTITELSQNKFEVSARALIKDIEEDLKIELRDPEEDYVTLGGLILSIAGKVPSVDE
CCCCEEEEECCCCHHHHHHHHHHHHHHHHCEEEECCCCHHHHHHHHHHHHHHCCCCCHHH
VIKYKNGMKFIIKDANERYINKIVLDLSDYKN
HHHHCCCCEEEEECCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SKKRTLVEKIAYRIFLFLFKKASVLKKCATEALMKDLPDLNIFNGLLKFRDCGIMDIMT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEECC
PRTEICAVDIESSEREIIKKIKNTCHTKIPIYKNNFDNVIGFFYVKDVIFNRDKNFNLKH
CCCEEEEEECCCCHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHHCCCCCCCHHH
IIQSVIFVPPSMKTTNLFVRMNSSKSCLAIVLDEYGGTDGLISMTDLIEELIPNIDSENE
HHHHHHHCCCCCCEEEEEEEECCCCCEEEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCC
INSEYTITELSQNKFEVSARALIKDIEEDLKIELRDPEEDYVTLGGLILSIAGKVPSVDE
CCCCEEEEECCCCHHHHHHHHHHHHHHHHCEEEECCCCHHHHHHHHHHHHHHCCCCCHHH
VIKYKNGMKFIIKDANERYINKIVLDLSDYKN
HHHHCCCCEEEEECCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA