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The map label for this gene is yacO [H]

Identifier: 225630621

GI number: 225630621

Start: 967299

End: 968063

Strand: Reverse

Name: yacO [H]

Synonym: WRi_008920

Alternate gene names: 225630621

Gene position: 968063-967299 (Counterclockwise)

Preceding gene: 225630623

Following gene: 225630620

Centisome position: 66.95

GC content: 33.46

Gene sequence:

>765_bases
ATGAAATCGTCAAAAACTAATGAGAATTTTTGGCTGTATGGAAAGCACACCTGCATGTCAGCACTGAAGAATAAAAATAG
GCGGTGTATAGAACTGTTAGCAACAGAAAATTTCTATAGAGAGCACAAAAAAGAAATTAGGCAATGTGTAGACAGTAAGG
GCATTAAAGTTCGATTAGTAGAAAGCAAAATACTTAATGACGTTTTACCCAAAGGTGCTAACCATCAGGGAATTGCTTTA
AATGTTGCCCCTATTCTTTATAACTTAAGCATTGAAGAAATAGCTGAAAGCTCGAACGATAGCTCTACTATAGTCATTTT
AGATCAAGTCACTGACACGCACAATATTGGGTCGATTTTAAGAACTTCAGCTTGTTTTAATGTCGACGCATTGGTTTTAC
CACATAACCATTCACCAAGTGAAAATGCATCTATTGCAAAAGCAGCAAGTGGAGCATTGGATATTGTCCCACTAATATAC
GTTACAAATATAGTAAAAACTATGCAGTATTTAAAAAAGGTCGGTTACTGGTGTTATGGGTTTGATTGCAATACTAAAGA
AAATATAGATGAAATAAAGAGTTTTGAGAAAAAAAGAGTAATTATTTTTGGTTCTGAAGAGAAAGGGGTACGAAGACTAG
TTAAAGAAAACTGTGATTATCTTTTAAAAATACCAATGTCAAATGCAATTAACAGTTTAAATGTTTCAAATGCAGCAGCA
ATAGGCCTATATTCTATTTATATTAAAACAAATGCCAGCGCATAG

Upstream 100 bases:

>100_bases
TCCGACATAAACGCATTAATCGAATTGTATAATTTTACAACAATATTCAAACATAGTAAAATGTTGCTTATTCTATAAAA
ACCAGATTTTCGATAATACG

Downstream 100 bases:

>100_bases
CTGTTTATAATAAAAACACTTGATAAAAATATGGTTTTATATTATAATGTGTTAAGTAATGGATAAAAGGAGTTATATTA
TGTCTTACATGAGAAATGAA

Product: RNA methyltransferase, TrmH family, group 3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 254; Mature: 254

Protein sequence:

>254_residues
MKSSKTNENFWLYGKHTCMSALKNKNRRCIELLATENFYREHKKEIRQCVDSKGIKVRLVESKILNDVLPKGANHQGIAL
NVAPILYNLSIEEIAESSNDSSTIVILDQVTDTHNIGSILRTSACFNVDALVLPHNHSPSENASIAKAASGALDIVPLIY
VTNIVKTMQYLKKVGYWCYGFDCNTKENIDEIKSFEKKRVIIFGSEEKGVRRLVKENCDYLLKIPMSNAINSLNVSNAAA
IGLYSIYIKTNASA

Sequences:

>Translated_254_residues
MKSSKTNENFWLYGKHTCMSALKNKNRRCIELLATENFYREHKKEIRQCVDSKGIKVRLVESKILNDVLPKGANHQGIAL
NVAPILYNLSIEEIAESSNDSSTIVILDQVTDTHNIGSILRTSACFNVDALVLPHNHSPSENASIAKAASGALDIVPLIY
VTNIVKTMQYLKKVGYWCYGFDCNTKENIDEIKSFEKKRVIIFGSEEKGVRRLVKENCDYLLKIPMSNAINSLNVSNAAA
IGLYSIYIKTNASA
>Mature_254_residues
MKSSKTNENFWLYGKHTCMSALKNKNRRCIELLATENFYREHKKEIRQCVDSKGIKVRLVESKILNDVLPKGANHQGIAL
NVAPILYNLSIEEIAESSNDSSTIVILDQVTDTHNIGSILRTSACFNVDALVLPHNHSPSENASIAKAASGALDIVPLIY
VTNIVKTMQYLKKVGYWCYGFDCNTKENIDEIKSFEKKRVIIFGSEEKGVRRLVKENCDYLLKIPMSNAINSLNVSNAAA
IGLYSIYIKTNASA

Specific function: Unknown

COG id: COG0566

COG function: function code J; rRNA methylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA methyltransferase TrmH family [H]

Homologues:

Organism=Homo sapiens, GI40068479, Length=254, Percent_Identity=25.1968503937008, Blast_Score=79, Evalue=3e-15,
Organism=Escherichia coli, GI1790623, Length=236, Percent_Identity=33.4745762711864, Blast_Score=127, Evalue=5e-31,
Organism=Saccharomyces cerevisiae, GI6324775, Length=283, Percent_Identity=24.3816254416961, Blast_Score=76, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004441
- InterPro:   IPR001537
- InterPro:   IPR013123 [H]

Pfam domain/function: PF00588 SpoU_methylase; PF08032 SpoU_sub_bind [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 28362; Mature: 28362

Theoretical pI: Translated: 8.81; Mature: 8.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSSKTNENFWLYGKHTCMSALKNKNRRCIELLATENFYREHKKEIRQCVDSKGIKVRLV
CCCCCCCCCEEEEEHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEH
ESKILNDVLPKGANHQGIALNVAPILYNLSIEEIAESSNDSSTIVILDQVTDTHNIGSIL
HHHHHHHHCCCCCCCCCEEEEEEHHEEECCHHHHHCCCCCCCEEEEEECCCCCCHHHHHH
RTSACFNVDALVLPHNHSPSENASIAKAASGALDIVPLIYVTNIVKTMQYLKKVGYWCYG
HHHHHCCCEEEEECCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEE
FDCNTKENIDEIKSFEKKRVIIFGSEEKGVRRLVKENCDYLLKIPMSNAINSLNVSNAAA
ECCCCCCCHHHHHHHCCCEEEEECCCCHHHHHHHHHCCCEEEEECHHHCCCCCCCCCCEE
IGLYSIYIKTNASA
EEEEEEEEEECCCC
>Mature Secondary Structure
MKSSKTNENFWLYGKHTCMSALKNKNRRCIELLATENFYREHKKEIRQCVDSKGIKVRLV
CCCCCCCCCEEEEEHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEH
ESKILNDVLPKGANHQGIALNVAPILYNLSIEEIAESSNDSSTIVILDQVTDTHNIGSIL
HHHHHHHHCCCCCCCCCEEEEEEHHEEECCHHHHHCCCCCCCEEEEEECCCCCCHHHHHH
RTSACFNVDALVLPHNHSPSENASIAKAASGALDIVPLIYVTNIVKTMQYLKKVGYWCYG
HHHHHCCCEEEEECCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEE
FDCNTKENIDEIKSFEKKRVIIFGSEEKGVRRLVKENCDYLLKIPMSNAINSLNVSNAAA
ECCCCCCCHHHHHHHCCCEEEEECCCCHHHHHHHHHCCCEEEEECHHHCCCCCCCCCCEE
IGLYSIYIKTNASA
EEEEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 7510287; 3145906 [H]