Click here to switch to the map view.

The map label for this gene is comF [H]

Identifier: 225630605

GI number: 225630605

Start: 950561

End: 951292

Strand: Direct

Name: comF [H]

Synonym: WRi_008760

Alternate gene names: 225630605

Gene position: 950561-951292 (Clockwise)

Preceding gene: 225630604

Following gene: 225630611

Centisome position: 65.74

GC content: 33.88

Gene sequence:

>732_bases
GTGAACCTTCTCTTACTAAAAAAAGCTACAAATCTCATATTTCCAAGCGTATGCGTAAGTTGCGAATGTATCATTGATGA
AAATCTTAATCTGTGTAGTGAATGCAACAAAAAAATCAATTTTCTAACTAAGCATTACTGCAATGTTTGTGGCGTAGTAA
TCTCAGACAATATTTATACGTGTGGTAAGTGCATCATCAATCCTCCACCGTTTAAAGTATTAAGATCAGTTTTTGCTTAT
GATCAACATAGTAGAAACATGATTATAAATTTCAAATTTTTTGATAATTTGAATTACGTAAAAATCTATGCAAAGTGGAT
ACACCAAGCTAATCAGGATACATTTCAGAACGCAGAGATCATAATTCCTATACCGTTACATAAAATGCGCTTGTTTAAAC
GTAAATATAATCAAGCAGCACTGCTTGCAAAAGAGTTGACTAAGTTATCCAATTTATCCTATACGCCATTTGCAATAAAA
CGCCTTCGCCATACTGCGCCTCAAGCTGGTCTTTCACTTAAACAGCGTGAAAAAAATTTAAAGAAGGCTTTTAAAACAAG
CAACAAGAAAATTATCGAAAATAAAATCGTGATATTAGTTGATGATGTGGTAACAACCGGAGCAACTGTAAGATCTTGCT
CTCAGGAAATTTTAAACTCCGGTGCAAAAGAAGTGAGAGTGCTATCACTTGCAAGAACGGTGAATGATTGGACCTCTTGC
ATAAAAAATTAG

Upstream 100 bases:

>100_bases
AGCATGAACTATATTGAAATGGAATAAAAAGTGAAAGAGTGTAAGCTTAAGTTACTTTAGCTATACTATATAAATTATTT
TATAATATATTTAATGAGTT

Downstream 100 bases:

>100_bases
CAGTCAGTATCATCCAAGTAGCTTGACTACTTGGATCTATTTTTTTCTAGATTCCAGCGCCAGCGTCACGCACATAGCTG
TACGAACATTGTTTGCCAAG

Product: putative competence protein F

Products: NA

Alternate protein names: DNA transformation protein ComF; Protein COM101A [H]

Number of amino acids: Translated: 243; Mature: 243

Protein sequence:

>243_residues
MNLLLLKKATNLIFPSVCVSCECIIDENLNLCSECNKKINFLTKHYCNVCGVVISDNIYTCGKCIINPPPFKVLRSVFAY
DQHSRNMIINFKFFDNLNYVKIYAKWIHQANQDTFQNAEIIIPIPLHKMRLFKRKYNQAALLAKELTKLSNLSYTPFAIK
RLRHTAPQAGLSLKQREKNLKKAFKTSNKKIIENKIVILVDDVVTTGATVRSCSQEILNSGAKEVRVLSLARTVNDWTSC
IKN

Sequences:

>Translated_243_residues
MNLLLLKKATNLIFPSVCVSCECIIDENLNLCSECNKKINFLTKHYCNVCGVVISDNIYTCGKCIINPPPFKVLRSVFAY
DQHSRNMIINFKFFDNLNYVKIYAKWIHQANQDTFQNAEIIIPIPLHKMRLFKRKYNQAALLAKELTKLSNLSYTPFAIK
RLRHTAPQAGLSLKQREKNLKKAFKTSNKKIIENKIVILVDDVVTTGATVRSCSQEILNSGAKEVRVLSLARTVNDWTSC
IKN
>Mature_243_residues
MNLLLLKKATNLIFPSVCVSCECIIDENLNLCSECNKKINFLTKHYCNVCGVVISDNIYTCGKCIINPPPFKVLRSVFAY
DQHSRNMIINFKFFDNLNYVKIYAKWIHQANQDTFQNAEIIIPIPLHKMRLFKRKYNQAALLAKELTKLSNLSYTPFAIK
RLRHTAPQAGLSLKQREKNLKKAFKTSNKKIIENKIVILVDDVVTTGATVRSCSQEILNSGAKEVRVLSLARTVNDWTSC
IKN

Specific function: Involved in transformation (competence for DNA uptake) [H]

COG id: COG1040

COG function: function code R; Predicted amidophosphoribosyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ComF/GntX family [H]

Homologues:

Organism=Escherichia coli, GI87082263, Length=229, Percent_Identity=29.6943231441048, Blast_Score=108, Evalue=3e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005222
- InterPro:   IPR000836 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: NA

Molecular weight: Translated: 27759; Mature: 27759

Theoretical pI: Translated: 10.06; Mature: 10.06

Prosite motif: PS00103 PUR_PYR_PR_TRANSFER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.5 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
4.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLLLLKKATNLIFPSVCVSCECIIDENLNLCSECNKKINFLTKHYCNVCGVVISDNIYT
CCEEEEEHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCEECCEEE
CGKCIINPPPFKVLRSVFAYDQHSRNMIINFKFFDNLNYVKIYAKWIHQANQDTFQNAEI
CCCEEECCCHHHHHHHHHHHCCCCCCEEEEEEEECCCCHHHHHHHHHHHCCCCHHCCCEE
IIPIPLHKMRLFKRKYNQAALLAKELTKLSNLSYTPFAIKRLRHTAPQAGLSLKQREKNL
EEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCHHHHHHHHH
KKAFKTSNKKIIENKIVILVDDVVTTGATVRSCSQEILNSGAKEVRVLSLARTVNDWTSC
HHHHHCCCCEEECCEEEEEECCHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
IKN
HCC
>Mature Secondary Structure
MNLLLLKKATNLIFPSVCVSCECIIDENLNLCSECNKKINFLTKHYCNVCGVVISDNIYT
CCEEEEEHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCEECCEEE
CGKCIINPPPFKVLRSVFAYDQHSRNMIINFKFFDNLNYVKIYAKWIHQANQDTFQNAEI
CCCEEECCCHHHHHHHHHHHCCCCCCEEEEEEEECCCCHHHHHHHHHHHCCCCHHCCCEE
IIPIPLHKMRLFKRKYNQAALLAKELTKLSNLSYTPFAIKRLRHTAPQAGLSLKQREKNL
EEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCHHHHHHHHH
KKAFKTSNKKIIENKIVILVDDVVTTGATVRSCSQEILNSGAKEVRVLSLARTVNDWTSC
HHHHHCCCCEEECCEEEEEECCHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
IKN
HCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1916268; 1856167; 7542800 [H]