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The map label for this gene is trxB [H]

Identifier: 225630372

GI number: 225630372

Start: 644216

End: 645154

Strand: Reverse

Name: trxB [H]

Synonym: WRi_005980

Alternate gene names: 225630372

Gene position: 645154-644216 (Counterclockwise)

Preceding gene: 225630373

Following gene: 225630371

Centisome position: 44.62

GC content: 39.08

Gene sequence:

>939_bases
GTGAAGAATTATAAATTTAGTACAAAAGTTCTTATTATTGGATCTGGGGCAGCGGGTTATGCTGCTGCTATATATGCAGC
ACGTGCAAACTTAGAGCCAATTGTAGTAACGGGAATGCAGCCTGGTGGTCAGCTTACAATTACTACAGATGTTGAAAACT
ATCCTGGTTTTGTTTCAATACAGGGTCCAGAACTAATGGAGCAAATGAGGTTGCATGCAGAAAAGGTTGGAGCAAAAATA
ATAGATGATGAGATAAAAAGCGTTGAACAACTTGAGGATTCTAATGAGTATAGGTTTAGATCTTCTGGTAATACTAATGA
CTACTACTCAGATGCAATTATAATTGCATCTGGTGCGCAAGCGAAGTGGCTTGGTCTCAAGAGTGAAAAGGAATTTCAAG
GTTACGGAGTTTCAGCTTGTGCAACTTGTGATGGTGCATTTTTTAGGAATAAAGTTGTAGCTGTGATTGGTGGTGGAAAC
ACTGCTGTTGAAGAAGCAATATTTTTAACTCGATTTGCCAAAGAAGTGATATTAATACACAGGCGTGATAAATTAAGAGC
GGAAAAAGTAATGCAAGATAGGCTCTTTAAAAATGATAAAATAAAAGTAATGTGGAACCATACCGTAGAGCAGATTCTTG
GAGAAGAAAATCCAAAAAGGGTTGCTGGTATTGCGATTAAATCAGCAGAAACCCAAGAATTAAAAGTGGATGGAGTGTTC
ATTGCAATCGGGCATGCACCAAATACGGGTATTTTTAAAGGCTTTGTTGAAATGGATGAGCAGGGTTACATCATTACAAA
ACCTGGAACAACTTTAACTAGTAGGGCAGGAGTGTTTGCTGCAGGTGATGTTCAAGATAAGGTATATCGTCAAGCAGTAG
TTGCAGCAGGAACAGGATGCATGGCTGCGCTTGATGCAGAAAAGTTTTTGGAGTCGTAG

Upstream 100 bases:

>100_bases
AATGAAGAGCATGGTGAGGTGTGTCCAGCAGGGTGGAAAAAAGGTAAGCCAGCAATGCAGGCAAGCGATGAAGGAGTAGC
TGATTATCTAAACTCATACA

Downstream 100 bases:

>100_bases
TTAATTCTAGGATTTTAGATAAATTGCTTGCAATTTTCCTTGTATCTTGAAAAAAGCATCTAGTGTTTTTAAGCTTAAGC
ATTAGGTGGAGAAGGGAAGA

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
MKNYKFSTKVLIIGSGAAGYAAAIYAARANLEPIVVTGMQPGGQLTITTDVENYPGFVSIQGPELMEQMRLHAEKVGAKI
IDDEIKSVEQLEDSNEYRFRSSGNTNDYYSDAIIIASGAQAKWLGLKSEKEFQGYGVSACATCDGAFFRNKVVAVIGGGN
TAVEEAIFLTRFAKEVILIHRRDKLRAEKVMQDRLFKNDKIKVMWNHTVEQILGEENPKRVAGIAIKSAETQELKVDGVF
IAIGHAPNTGIFKGFVEMDEQGYIITKPGTTLTSRAGVFAAGDVQDKVYRQAVVAAGTGCMAALDAEKFLES

Sequences:

>Translated_312_residues
MKNYKFSTKVLIIGSGAAGYAAAIYAARANLEPIVVTGMQPGGQLTITTDVENYPGFVSIQGPELMEQMRLHAEKVGAKI
IDDEIKSVEQLEDSNEYRFRSSGNTNDYYSDAIIIASGAQAKWLGLKSEKEFQGYGVSACATCDGAFFRNKVVAVIGGGN
TAVEEAIFLTRFAKEVILIHRRDKLRAEKVMQDRLFKNDKIKVMWNHTVEQILGEENPKRVAGIAIKSAETQELKVDGVF
IAIGHAPNTGIFKGFVEMDEQGYIITKPGTTLTSRAGVFAAGDVQDKVYRQAVVAAGTGCMAALDAEKFLES
>Mature_312_residues
MKNYKFSTKVLIIGSGAAGYAAAIYAARANLEPIVVTGMQPGGQLTITTDVENYPGFVSIQGPELMEQMRLHAEKVGAKI
IDDEIKSVEQLEDSNEYRFRSSGNTNDYYSDAIIIASGAQAKWLGLKSEKEFQGYGVSACATCDGAFFRNKVVAVIGGGN
TAVEEAIFLTRFAKEVILIHRRDKLRAEKVMQDRLFKNDKIKVMWNHTVEQILGEENPKRVAGIAIKSAETQELKVDGVF
IAIGHAPNTGIFKGFVEMDEQGYIITKPGTTLTSRAGVFAAGDVQDKVYRQAVVAAGTGCMAALDAEKFLES

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=316, Percent_Identity=53.1645569620253, Blast_Score=319, Evalue=2e-88,
Organism=Escherichia coli, GI87081763, Length=321, Percent_Identity=31.7757009345794, Blast_Score=142, Evalue=2e-35,
Organism=Saccharomyces cerevisiae, GI6320560, Length=317, Percent_Identity=47.6340694006309, Blast_Score=271, Evalue=7e-74,
Organism=Saccharomyces cerevisiae, GI6321898, Length=317, Percent_Identity=47.6340694006309, Blast_Score=269, Evalue=5e-73,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 33948; Mature: 33948

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNYKFSTKVLIIGSGAAGYAAAIYAARANLEPIVVTGMQPGGQLTITTDVENYPGFVSI
CCCCEEEEEEEEEECCCCHHHHHHHHHHCCCCEEEEECCCCCCEEEEEEECCCCCCEEEE
QGPELMEQMRLHAEKVGAKIIDDEIKSVEQLEDSNEYRFRSSGNTNDYYSDAIIIASGAQ
CCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCEEEECCCCCCCEECCEEEEECCCC
AKWLGLKSEKEFQGYGVSACATCDGAFFRNKVVAVIGGGNTAVEEAIFLTRFAKEVILIH
EEEEECCCCCCCCCCCCEEEECCCCHHHCCEEEEEEECCCHHHHHHHHHHHHHHHHEEEE
RRDKLRAEKVMQDRLFKNDKIKVMWNHTVEQILGEENPKRVAGIAIKSAETQELKVDGVF
CCHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHCCCCCCEEEEEEEECCCCCEEEEEEEE
IAIGHAPNTGIFKGFVEMDEQGYIITKPGTTLTSRAGVFAAGDVQDKVYRQAVVAAGTGC
EEEECCCCCCCEEHHEEECCCCEEEECCCCCEECCCCEEEECCHHHHHHHHHHHHCCCCH
MAALDAEKFLES
HHHHCHHHHHCC
>Mature Secondary Structure
MKNYKFSTKVLIIGSGAAGYAAAIYAARANLEPIVVTGMQPGGQLTITTDVENYPGFVSI
CCCCEEEEEEEEEECCCCHHHHHHHHHHCCCCEEEEECCCCCCEEEEEEECCCCCCEEEE
QGPELMEQMRLHAEKVGAKIIDDEIKSVEQLEDSNEYRFRSSGNTNDYYSDAIIIASGAQ
CCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCEEEECCCCCCCEECCEEEEECCCC
AKWLGLKSEKEFQGYGVSACATCDGAFFRNKVVAVIGGGNTAVEEAIFLTRFAKEVILIH
EEEEECCCCCCCCCCCCEEEECCCCHHHCCEEEEEEECCCHHHHHHHHHHHHHHHHEEEE
RRDKLRAEKVMQDRLFKNDKIKVMWNHTVEQILGEENPKRVAGIAIKSAETQELKVDGVF
CCHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHCCCCCCEEEEEEEECCCCCEEEEEEEE
IAIGHAPNTGIFKGFVEMDEQGYIITKPGTTLTSRAGVFAAGDVQDKVYRQAVVAAGTGC
EEEECCCCCCCEEHHEEECCCCEEEECCCCCEECCCCEEEECCHHHHHHHHHHHHCCCCH
MAALDAEKFLES
HHHHCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA