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The map label for this gene is ribB [H]

Identifier: 225630272

GI number: 225630272

Start: 536104

End: 536748

Strand: Reverse

Name: ribB [H]

Synonym: WRi_004900

Alternate gene names: 225630272

Gene position: 536748-536104 (Counterclockwise)

Preceding gene: 225630273

Following gene: 225630271

Centisome position: 37.12

GC content: 37.52

Gene sequence:

>645_bases
ATGGTACAGGCCACTTATGCTTCAATGAGTCTACCAGGTATTTCTTCTGTGGAAGATGTATTAGAGGATGCTCGTTCCGG
TAAATTATTCATTTTAGTTGATGATGAAAATAGAGAAAATGAAGGCGATTTGATTGTCTTAGCTGAGAAAATAAAGCCGG
AACATATGGCTTTTATGGTTAGGTACGGTACAGGGGTTGTTTGCTTAGCAATGACTAAATTTCACATGAAAAGGTTGGGC
CTTAATTTCATGGAAAAGAAAAATATTGGTGAAAATCATACCGCATTTACTACATCAATTGATGCACGTTATGGCATTAC
AACCGGTGTTTCAGCAGAGGATAGAACGAAAACTATACATGCTGCTATCAACAAGGATGGTACTCAGGATGACATCATAA
CTCCAGGTCATGTTTTTCCTGTAATTGCACATAAAGGTGGGGTGGCACAACGTGCTGGTCATACTGAAGCGAGTGTTGAA
ATGGCGAAGTTAGTAGGGTTTGATCATTCAGCAGTTATTTGTGAATTAGTGAATGATGATGGCTCTATGATGCGCTTACC
TCAGTTACTTAAATTTGCTGAACAACATAAAATTAAGTTAACTACCATCGACAAACTTATCAGTTACGTTAAAAATTTAA
ACTAG

Upstream 100 bases:

>100_bases
TGCCTTAATCGGCAAAAAAGTCGGTGAATATGTGGAAGTGACAGTGCCAAATGGAGAGAAATTGTATAAAATAGTTAAGA
TTGAATTTAAGTAAATTATT

Downstream 100 bases:

>100_bases
CGTTTATAAATTTGTATAATTTAAGTGTTAAAATATAGAATTTCTATAAATTATACAAGCACAGAATTTTCATGTTTAGA
GTTGCTAAGTTTTTGACCTT

Product: 3,4-dihydroxy-2-butanone 4-phosphate synthase, putative

Products: NA

Alternate protein names: DHBP synthase [H]

Number of amino acids: Translated: 214; Mature: 214

Protein sequence:

>214_residues
MVQATYASMSLPGISSVEDVLEDARSGKLFILVDDENRENEGDLIVLAEKIKPEHMAFMVRYGTGVVCLAMTKFHMKRLG
LNFMEKKNIGENHTAFTTSIDARYGITTGVSAEDRTKTIHAAINKDGTQDDIITPGHVFPVIAHKGGVAQRAGHTEASVE
MAKLVGFDHSAVICELVNDDGSMMRLPQLLKFAEQHKIKLTTIDKLISYVKNLN

Sequences:

>Translated_214_residues
MVQATYASMSLPGISSVEDVLEDARSGKLFILVDDENRENEGDLIVLAEKIKPEHMAFMVRYGTGVVCLAMTKFHMKRLG
LNFMEKKNIGENHTAFTTSIDARYGITTGVSAEDRTKTIHAAINKDGTQDDIITPGHVFPVIAHKGGVAQRAGHTEASVE
MAKLVGFDHSAVICELVNDDGSMMRLPQLLKFAEQHKIKLTTIDKLISYVKNLN
>Mature_214_residues
MVQATYASMSLPGISSVEDVLEDARSGKLFILVDDENRENEGDLIVLAEKIKPEHMAFMVRYGTGVVCLAMTKFHMKRLG
LNFMEKKNIGENHTAFTTSIDARYGITTGVSAEDRTKTIHAAINKDGTQDDIITPGHVFPVIAHKGGVAQRAGHTEASVE
MAKLVGFDHSAVICELVNDDGSMMRLPQLLKFAEQHKIKLTTIDKLISYVKNLN

Specific function: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate [H]

COG id: COG0108

COG function: function code H; 3,4-dihydroxy-2-butanone 4-phosphate synthase

Gene ontology:

Cell location: Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the GTP cyclohydrolase II family [H]

Homologues:

Organism=Escherichia coli, GI1789420, Length=209, Percent_Identity=44.4976076555024, Blast_Score=191, Evalue=3e-50,
Organism=Saccharomyces cerevisiae, GI6320695, Length=207, Percent_Identity=41.5458937198068, Blast_Score=160, Evalue=1e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR000422
- InterPro:   IPR000926
- InterPro:   IPR016299 [H]

Pfam domain/function: PF00926 DHBP_synthase; PF00925 GTP_cyclohydro2 [H]

EC number: =4.1.99.12 [H]

Molecular weight: Translated: 23559; Mature: 23559

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVQATYASMSLPGISSVEDVLEDARSGKLFILVDDENRENEGDLIVLAEKIKPEHMAFMV
CCEECCCCCCCCCCCHHHHHHHHHCCCEEEEEECCCCCCCCCCEEEEECCCCCCCEEEEE
RYGTGVVCLAMTKFHMKRLGLNFMEKKNIGENHTAFTTSIDARYGITTGVSAEDRTKTIH
ECCCCEEEEHHHHHHHHHHCCCHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCCHHEEEE
AAINKDGTQDDIITPGHVFPVIAHKGGVAQRAGHTEASVEMAKLVGFDHSAVICELVNDD
EEECCCCCCCCCCCCCCEEEEEECCCCCHHHCCCCHHHHHHHHHHCCCCCEEEEEEECCC
GSMMRLPQLLKFAEQHKIKLTTIDKLISYVKNLN
CCHHHHHHHHHHHHHCCEEEHHHHHHHHHHHCCC
>Mature Secondary Structure
MVQATYASMSLPGISSVEDVLEDARSGKLFILVDDENRENEGDLIVLAEKIKPEHMAFMV
CCEECCCCCCCCCCCHHHHHHHHHCCCEEEEEECCCCCCCCCCEEEEECCCCCCCEEEEE
RYGTGVVCLAMTKFHMKRLGLNFMEKKNIGENHTAFTTSIDARYGITTGVSAEDRTKTIH
ECCCCEEEEHHHHHHHHHHCCCHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCCHHEEEE
AAINKDGTQDDIITPGHVFPVIAHKGGVAQRAGHTEASVEMAKLVGFDHSAVICELVNDD
EEECCCCCCCCCCCCCCEEEEEECCCCCHHHCCCCHHHHHHHHHHCCCCCEEEEEEECCC
GSMMRLPQLLKFAEQHKIKLTTIDKLISYVKNLN
CCHHHHHHHHHHHHHCCEEEHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]