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The map label for this gene is ubiG [H]

Identifier: 225630228

GI number: 225630228

Start: 469697

End: 470872

Strand: Reverse

Name: ubiG [H]

Synonym: WRi_004370

Alternate gene names: 225630228

Gene position: 470872-469697 (Counterclockwise)

Preceding gene: 225630230

Following gene: 225630227

Centisome position: 32.57

GC content: 36.05

Gene sequence:

>1176_bases
ATGTTAGGTATAGTATCAATTGCCTCAGATCATTCTGGTTATGAATTAAAATCAGAAATAAAACCTTACCTGGAAGCCCT
AGGTTACAGAGTGGTAGATCAAGGCTGCACTGCTCAGCAAAAGTGCGTGGATTATCCAGACTATGCTGTTAAAGTTGTAG
AAGATATAACAAGCAAAAAAGCAAATTATGGGATATTAATTTGTGGTACAGGTTTGGGCATGAGTACTGTGGCAAATCGT
TTTGAAGGAATCTACGCTGCTTTATGTAACAGTGTTGAGATCGCAAAATTAGCTCGCGAGCATGGCAACGCAAATGTACT
GTGTCTTGGTGCAGGGTTTACTGCGAGTGGATTAGCAAAAGACATAGTCAAACAATTCCTCGAAACAGAATTTTCAAAAG
AAAGCAGACATAAAAAACGCCTTGATAAACTCAGCAATATAACCTCTAAGAAAAAAAAAACAAAAACTTATAACGAAGAT
GAAATATCAAAATTCGCTAAAATGGCAGGCCAGTGGTGGGATGAGAACGGCAAATTCAAACCATTGCACATAATGAATCC
TGTTAGAGTATCTTACATTATTGAGAAAATAAAAGAGTTAAAAAAATGCAATTTGAAAGAATTATCATTGCTTGATGTTG
GATGCGGTGGTGGCATTTTGTCAGAGTCAATGGCACGCGTTGGCATTAACGTTGTGGGAATAGATGTATGTGAAGAAAAC
ATAAAAGTAGCGCATTCACATGCAAAAAAAGTAGGGTTAAATATAGAATATATACACACCAGCATTGAAGAGCTAAGCAA
TGACAAGAAGTACGACGTGGTTCTGTTGATGGAAGTAGTTGAACATGTGGATAATTTAGAGCTTTTCATGAAAAAAGCGA
TAGAACTGCTAAAACCGAATGGGCTGATATTTATATCCACAATAAATAGAACTATCAAATCCTTCTGCCTTGCAATAATT
GGTGCAGAGTACATATTAAATTGGCTGCCAAAAGGTACACATAACTGGAATAAATTTCTCAAGCCGTCAGAAATTGCAAA
TCACTTAAGAGAAAATAATGTAACGCTGCAAAACATGGCTGGTATGGAGTACAACGTAATAAAGCGTGAGTGGAATCTAA
CTAAAGGAGTAGATGTTAATTATATACTTTGTGGTTTGTTAGATTTAACTCTATAA

Upstream 100 bases:

>100_bases
AGGAAAACCTTAGCTATAGCTTTAGAACTCCCAAAAGGTCAGAAGCATTGAATGACTTGACAGAAAGTTCAAACCCATAT
AAAATGTCCTTATTTCTTAT

Downstream 100 bases:

>100_bases
AAGCACCATTTTCACTTCCAATACTTTGAAGGATCTTGGCCAGCTTTTATACAGTAGCCTTTATTAGTTAGCGCCCAACC
GGAACGACAAGCATAACCTG

Product: 3-demethylubiquinone-9 3-methyltransferase

Products: NA

Alternate protein names: 3,4-dihydroxy-5-hexaprenylbenzoate methyltransferase; DHHB methyltransferase [H]

Number of amino acids: Translated: 391; Mature: 391

Protein sequence:

>391_residues
MLGIVSIASDHSGYELKSEIKPYLEALGYRVVDQGCTAQQKCVDYPDYAVKVVEDITSKKANYGILICGTGLGMSTVANR
FEGIYAALCNSVEIAKLAREHGNANVLCLGAGFTASGLAKDIVKQFLETEFSKESRHKKRLDKLSNITSKKKKTKTYNED
EISKFAKMAGQWWDENGKFKPLHIMNPVRVSYIIEKIKELKKCNLKELSLLDVGCGGGILSESMARVGINVVGIDVCEEN
IKVAHSHAKKVGLNIEYIHTSIEELSNDKKYDVVLLMEVVEHVDNLELFMKKAIELLKPNGLIFISTINRTIKSFCLAII
GAEYILNWLPKGTHNWNKFLKPSEIANHLRENNVTLQNMAGMEYNVIKREWNLTKGVDVNYILCGLLDLTL

Sequences:

>Translated_391_residues
MLGIVSIASDHSGYELKSEIKPYLEALGYRVVDQGCTAQQKCVDYPDYAVKVVEDITSKKANYGILICGTGLGMSTVANR
FEGIYAALCNSVEIAKLAREHGNANVLCLGAGFTASGLAKDIVKQFLETEFSKESRHKKRLDKLSNITSKKKKTKTYNED
EISKFAKMAGQWWDENGKFKPLHIMNPVRVSYIIEKIKELKKCNLKELSLLDVGCGGGILSESMARVGINVVGIDVCEEN
IKVAHSHAKKVGLNIEYIHTSIEELSNDKKYDVVLLMEVVEHVDNLELFMKKAIELLKPNGLIFISTINRTIKSFCLAII
GAEYILNWLPKGTHNWNKFLKPSEIANHLRENNVTLQNMAGMEYNVIKREWNLTKGVDVNYILCGLLDLTL
>Mature_391_residues
MLGIVSIASDHSGYELKSEIKPYLEALGYRVVDQGCTAQQKCVDYPDYAVKVVEDITSKKANYGILICGTGLGMSTVANR
FEGIYAALCNSVEIAKLAREHGNANVLCLGAGFTASGLAKDIVKQFLETEFSKESRHKKRLDKLSNITSKKKKTKTYNED
EISKFAKMAGQWWDENGKFKPLHIMNPVRVSYIIEKIKELKKCNLKELSLLDVGCGGGILSESMARVGINVVGIDVCEEN
IKVAHSHAKKVGLNIEYIHTSIEELSNDKKYDVVLLMEVVEHVDNLELFMKKAIELLKPNGLIFISTINRTIKSFCLAII
GAEYILNWLPKGTHNWNKFLKPSEIANHLRENNVTLQNMAGMEYNVIKREWNLTKGVDVNYILCGLLDLTL

Specific function: Ubiquinone biosynthesis. [C]

COG id: COG2227

COG function: function code H; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. UbiG/COQ3 family [H]

Homologues:

Organism=Homo sapiens, GI118600965, Length=236, Percent_Identity=38.5593220338983, Blast_Score=177, Evalue=1e-44,
Organism=Escherichia coli, GI1788564, Length=228, Percent_Identity=42.9824561403509, Blast_Score=203, Evalue=2e-53,
Organism=Escherichia coli, GI1790528, Length=147, Percent_Identity=36.0544217687075, Blast_Score=103, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI115533050, Length=232, Percent_Identity=34.4827586206897, Blast_Score=148, Evalue=4e-36,
Organism=Saccharomyces cerevisiae, GI6324476, Length=273, Percent_Identity=31.8681318681319, Blast_Score=122, Evalue=1e-28,
Organism=Drosophila melanogaster, GI281365311, Length=251, Percent_Identity=31.0756972111554, Blast_Score=137, Evalue=2e-32,
Organism=Drosophila melanogaster, GI24585589, Length=213, Percent_Identity=33.3333333333333, Blast_Score=134, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013216
- InterPro:   IPR010233 [H]

Pfam domain/function: PF08241 Methyltransf_11 [H]

EC number: =2.1.1.64 [H]

Molecular weight: Translated: 43765; Mature: 43765

Theoretical pI: Translated: 8.24; Mature: 8.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLGIVSIASDHSGYELKSEIKPYLEALGYRVVDQGCTAQQKCVDYPDYAVKVVEDITSKK
CCEEEEECCCCCCCHHHHHHHHHHHHHCHHHHHCCCCHHHHHCCCCHHHHHHHHHHHHCC
ANYGILICGTGLGMSTVANRFEGIYAALCNSVEIAKLAREHGNANVLCLGAGFTASGLAK
CCCCEEEEECCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCEEEEECCCCHHHHHH
DIVKQFLETEFSKESRHKKRLDKLSNITSKKKKTKTYNEDEISKFAKMAGQWWDENGKFK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCC
PLHIMNPVRVSYIIEKIKELKKCNLKELSLLDVGCGGGILSESMARVGINVVGIDVCEEN
EEECCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHCCEEEEEEHHHHH
IKVAHSHAKKVGLNIEYIHTSIEELSNDKKYDVVLLMEVVEHVDNLELFMKKAIELLKPN
HHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GLIFISTINRTIKSFCLAIIGAEYILNWLPKGTHNWNKFLKPSEIANHLRENNVTLQNMA
CEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCHHHHHHHHHHCCCCHHHHC
GMEYNVIKREWNLTKGVDVNYILCGLLDLTL
CCEEEHHHHHCCCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MLGIVSIASDHSGYELKSEIKPYLEALGYRVVDQGCTAQQKCVDYPDYAVKVVEDITSKK
CCEEEEECCCCCCCHHHHHHHHHHHHHCHHHHHCCCCHHHHHCCCCHHHHHHHHHHHHCC
ANYGILICGTGLGMSTVANRFEGIYAALCNSVEIAKLAREHGNANVLCLGAGFTASGLAK
CCCCEEEEECCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCEEEEECCCCHHHHHH
DIVKQFLETEFSKESRHKKRLDKLSNITSKKKKTKTYNEDEISKFAKMAGQWWDENGKFK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCC
PLHIMNPVRVSYIIEKIKELKKCNLKELSLLDVGCGGGILSESMARVGINVVGIDVCEEN
EEECCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHCCEEEEEEHHHHH
IKVAHSHAKKVGLNIEYIHTSIEELSNDKKYDVVLLMEVVEHVDNLELFMKKAIELLKPN
HHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GLIFISTINRTIKSFCLAIIGAEYILNWLPKGTHNWNKFLKPSEIANHLRENNVTLQNMA
CEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCHHHHHHHHHHCCCCHHHHC
GMEYNVIKREWNLTKGVDVNYILCGLLDLTL
CCEEEHHHHHCCCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA