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The map label for this gene is dapB [H]

Identifier: 225630214

GI number: 225630214

Start: 452345

End: 453130

Strand: Reverse

Name: dapB [H]

Synonym: WRi_004200

Alternate gene names: 225630214

Gene position: 453130-452345 (Counterclockwise)

Preceding gene: 225630215

Following gene: 225630213

Centisome position: 31.34

GC content: 37.4

Gene sequence:

>786_bases
ATGAAAATCAGAGTTGGAGTAATAGGCTGCTTAGGCAGAATGGGCAAAAAAATACTCAATGAATTAATTACAAATACCAA
AGTGGAAATAGCAGGTGCTGTTGCCCGTTCAGGCAGTAAGTACATAGATTCAGATATTGGACCAATTATAGCCAATCTAG
GAATTAAGGTTACAAGTTCTATCAGTGACGTATTTGAGTCATCTGACGTTGTAATAGATTTTACAACTAAAGAATGTATG
TTAGACTGCCTTAAAGCAGCTGTAAAATTTAAAACACCGCTGGTTAGTGGCACAACTGGAATAGAAGGTGTCGATTTGAA
AGAATATGCTGCTGAAGTTCCAATATTATGGTCAGCAAATATGAGTGTTGGGGTTAATGTGTTGCTGAAATTGGTAAAAA
AAGCTGCTGAGCTTTTAGGTAATGAATATGACGTTGAGATTTGGGAAATGCATCATAACTTAAAAAAGGATTCACCATCT
GGAACAGCTATAGAACTTGGCAAAACAATTGCTAACGCTTCAAAAGTGGATTTTCAGTCCAATCAATATTTACATAGTGG
TTCAAACATAAGGAAAAAGGGGGGAATAGGTTTTGCAGTATCTCGTGGAGGTGGAGTAATAGGAGATCACAGCGTGATGT
TTGTTAATTCTGATGAACGGATAGAACTAAACCACAAAGCAATTGATCGCACAACATTTGCTAGAGGAGCTGTTCAAGCA
GCAGTATGGCTATACGAAAATAAAAGAGAAATTCCGGGGCTCTATTCAATGCAGGATGTGATATGA

Upstream 100 bases:

>100_bases
GGGATCTGAAATTGCAGTGTTCGTACAGCTATAGAATATAGATCAGAAGTGACAGAGCTTAAAAAAAGGCCTAACATTCT
TAATAAACGTAAAAAGCTTT

Downstream 100 bases:

>100_bases
GCAATACACGTGCCTCTGTTAAAGATTTAAATCTCTGGTATGGCTCTAAGCAAGTTTTATTCGATATAAATTTGAATATT
TATAAAAGAAAAGTTACTAC

Product: dihydrodipicolinate reductase

Products: NA

Alternate protein names: DHPR [H]

Number of amino acids: Translated: 261; Mature: 261

Protein sequence:

>261_residues
MKIRVGVIGCLGRMGKKILNELITNTKVEIAGAVARSGSKYIDSDIGPIIANLGIKVTSSISDVFESSDVVIDFTTKECM
LDCLKAAVKFKTPLVSGTTGIEGVDLKEYAAEVPILWSANMSVGVNVLLKLVKKAAELLGNEYDVEIWEMHHNLKKDSPS
GTAIELGKTIANASKVDFQSNQYLHSGSNIRKKGGIGFAVSRGGGVIGDHSVMFVNSDERIELNHKAIDRTTFARGAVQA
AVWLYENKREIPGLYSMQDVI

Sequences:

>Translated_261_residues
MKIRVGVIGCLGRMGKKILNELITNTKVEIAGAVARSGSKYIDSDIGPIIANLGIKVTSSISDVFESSDVVIDFTTKECM
LDCLKAAVKFKTPLVSGTTGIEGVDLKEYAAEVPILWSANMSVGVNVLLKLVKKAAELLGNEYDVEIWEMHHNLKKDSPS
GTAIELGKTIANASKVDFQSNQYLHSGSNIRKKGGIGFAVSRGGGVIGDHSVMFVNSDERIELNHKAIDRTTFARGAVQA
AVWLYENKREIPGLYSMQDVI
>Mature_261_residues
MKIRVGVIGCLGRMGKKILNELITNTKVEIAGAVARSGSKYIDSDIGPIIANLGIKVTSSISDVFESSDVVIDFTTKECM
LDCLKAAVKFKTPLVSGTTGIEGVDLKEYAAEVPILWSANMSVGVNVLLKLVKKAAELLGNEYDVEIWEMHHNLKKDSPS
GTAIELGKTIANASKVDFQSNQYLHSGSNIRKKGGIGFAVSRGGGVIGDHSVMFVNSDERIELNHKAIDRTTFARGAVQA
AVWLYENKREIPGLYSMQDVI

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; second step. [C]

COG id: COG0289

COG function: function code E; Dihydrodipicolinate reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydrodipicolinate reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786214, Length=268, Percent_Identity=38.4328358208955, Blast_Score=176, Evalue=2e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022663
- InterPro:   IPR000846
- InterPro:   IPR022664
- InterPro:   IPR011770
- InterPro:   IPR016040 [H]

Pfam domain/function: PF05173 DapB_C; PF01113 DapB_N [H]

EC number: =1.3.1.26 [H]

Molecular weight: Translated: 28231; Mature: 28231

Theoretical pI: Translated: 8.07; Mature: 8.07

Prosite motif: PS01298 DAPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIRVGVIGCLGRMGKKILNELITNTKVEIAGAVARSGSKYIDSDIGPIIANLGIKVTSS
CEEEEHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHCCCHHHHCCHHHHHHHCCCEEEHH
ISDVFESSDVVIDFTTKECMLDCLKAAVKFKTPLVSGTTGIEGVDLKEYAAEVPILWSAN
HHHHHCCCCEEEEECHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHCCCCEEEECC
MSVGVNVLLKLVKKAAELLGNEYDVEIWEMHHNLKKDSPSGTAIELGKTIANASKVDFQS
CCHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHCCCCCCCCEEHHHHHHHCCHHCCCCC
NQYLHSGSNIRKKGGIGFAVSRGGGVIGDHSVMFVNSDERIELNHKAIDRTTFARGAVQA
CCEEECCCCCCCCCCEEEEEECCCCEECCCEEEEECCCCEEEECHHHHHHHHHHHHHHHH
AVWLYENKREIPGLYSMQDVI
HHEEECCCCCCCCCCHHHHCC
>Mature Secondary Structure
MKIRVGVIGCLGRMGKKILNELITNTKVEIAGAVARSGSKYIDSDIGPIIANLGIKVTSS
CEEEEHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHCCCHHHHCCHHHHHHHCCCEEEHH
ISDVFESSDVVIDFTTKECMLDCLKAAVKFKTPLVSGTTGIEGVDLKEYAAEVPILWSAN
HHHHHCCCCEEEEECHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHCCCCEEEECC
MSVGVNVLLKLVKKAAELLGNEYDVEIWEMHHNLKKDSPSGTAIELGKTIANASKVDFQS
CCHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHCCCCCCCCEEHHHHHHHCCHHCCCCC
NQYLHSGSNIRKKGGIGFAVSRGGGVIGDHSVMFVNSDERIELNHKAIDRTTFARGAVQA
CCEEECCCCCCCCCCEEEEEECCCCEECCCEEEEECCCCEEEECHHHHHHHHHHHHHHHH
AVWLYENKREIPGLYSMQDVI
HHEEECCCCCCCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA