Click here to switch to the map view.

The map label for this gene is trkG [H]

Identifier: 225630210

GI number: 225630210

Start: 445961

End: 447421

Strand: Direct

Name: trkG [H]

Synonym: WRi_004130

Alternate gene names: 225630210

Gene position: 445961-447421 (Clockwise)

Preceding gene: 225630208

Following gene: 225630212

Centisome position: 30.84

GC content: 34.7

Gene sequence:

>1461_bases
ATGAAAAATCATCAACGTTTACAAAATTTGCGTTCAATTGTATTTATTGTGGGAATATTCCTATTGCTGTTTAGCTTAGC
AATGCTTATTCCTGCTATTACTAATAAATGTCTCAGCTACAAATGGAAAAATTTCCTCGCTGGATTCATAATTACCTGCA
CATCTGGCGCAATTTTTATTTTACTCGGTAAATTAAGTAGATTGCATGGAATGCCAGCAATTTTTGCGATTACTAGTTGC
ACCTGGATTGCCTTGTCTCTGTTTGCAGCTATTCCTTTCTATTTTGATAATCTGAGCTATGTTGATGCATTGTTTGAAAC
GATATCTGGCATCACAACCACAGGGGCAACTATATTTAATGATATTGAAAAACAATCTCCAGGAATACTGCTGTGGAGAG
CAATGCTACACGGCATGGGGGGTTTTGGTGTAATCACTTTAGGAATTGCAGTTTTTCCTATGTTTAAGGTTCTCAGCCTA
AATAATTTACTTTATTCTGAATATTCAGATGCTACCAAAAGGAAGTTGCCGAACACGCGAAGCGTAGTGATTCATGTTAC
GGCAATATATTATGGCTTAATTTTGTTATGCATATTTTCCTATTATCTAGCTGGTATGCCACTATTTGATGCAATATGTC
ACGGAATGTCTGCTGTATCAACTGGTGGATTTGCTAACTATAATGATTCTATAGGGCACTATAATAATCCCATACTAGAA
GCCATAACGATCGTTTTTATGATTTTGGGTTCTCTGCCTTTTCTTAGCTATTTAAAAATTATAAGACGGTTAGACATTTG
CTATGATGAACAGGTCTCTTACTTTGTTAAGATAGCTACTATCTCATCTTTATTTGCTTGTTTTTGGTTGTATAAAAATG
TTGATTTAGGAGTGTCATTATCATTTAGATGCAGCACATTTACCATCACTTCCTTGATTACGTCAACTGGTTATGCAATC
TGTAATCATATAGATTGGAGTTTCATTTCAGTCTTAGCTTTTTTTCTAACCTTTGTTGGTGGATGTAGCGGTTCTTCAAG
TGGTGGTGTCAAAATCTTTCGTTTGATCATTTTTCTAAGATCTATAGAAAATCACTTTCGCCTTTTATTGAACCCAGGCG
CAGGCGATAGGGTAAAATTCAATGGAAAAACCCTGGAGAATGATGAAGTTCACTCTGTCTTTATATTTTTTGCAATTTTC
ATGTTAACGTTTACCATTTCATCAATAGTGATGTCTTACTTAAGCAATGCAGACTTTATAACTAGCATCAGTTCAGTCTC
TGCAACGCTTACAAACTCTGGCCCGGGATTTAGTAATTTAATAGGTCCTTCGGGTAATTATTCCTCTTTCAGTAATGAAG
TAAAATTATTTCTATCGTTTTTAATGCTGCTTGGCAGACTTGAAATATTGCCAATCTATTTTTGTATAGGCAATTTATTC
TTATTTAATAGAAAGAAATAG

Upstream 100 bases:

>100_bases
AAGTAAATCAAGTATATTGTTAATAACTGTTAATAAAGGCCAACAAAATGCTTGACGTTAGAGTAGCTTTTATGGCTTTG
TATAGCGAGGAAGTAATTCT

Downstream 100 bases:

>100_bases
TTGGTGAAGTTGTGAAATTTGATATTATAGCTAAACTGACTTACGACAATTTGAAAAACCGTCATTCCGCTACTTGTTAG
CGGCTGAGATACCGCGCACA

Product: Trk system potassium uptake protein TrkH

Products: Proton [Cytoplasm]; K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 486; Mature: 486

Protein sequence:

>486_residues
MKNHQRLQNLRSIVFIVGIFLLLFSLAMLIPAITNKCLSYKWKNFLAGFIITCTSGAIFILLGKLSRLHGMPAIFAITSC
TWIALSLFAAIPFYFDNLSYVDALFETISGITTTGATIFNDIEKQSPGILLWRAMLHGMGGFGVITLGIAVFPMFKVLSL
NNLLYSEYSDATKRKLPNTRSVVIHVTAIYYGLILLCIFSYYLAGMPLFDAICHGMSAVSTGGFANYNDSIGHYNNPILE
AITIVFMILGSLPFLSYLKIIRRLDICYDEQVSYFVKIATISSLFACFWLYKNVDLGVSLSFRCSTFTITSLITSTGYAI
CNHIDWSFISVLAFFLTFVGGCSGSSSGGVKIFRLIIFLRSIENHFRLLLNPGAGDRVKFNGKTLENDEVHSVFIFFAIF
MLTFTISSIVMSYLSNADFITSISSVSATLTNSGPGFSNLIGPSGNYSSFSNEVKLFLSFLMLLGRLEILPIYFCIGNLF
LFNRKK

Sequences:

>Translated_486_residues
MKNHQRLQNLRSIVFIVGIFLLLFSLAMLIPAITNKCLSYKWKNFLAGFIITCTSGAIFILLGKLSRLHGMPAIFAITSC
TWIALSLFAAIPFYFDNLSYVDALFETISGITTTGATIFNDIEKQSPGILLWRAMLHGMGGFGVITLGIAVFPMFKVLSL
NNLLYSEYSDATKRKLPNTRSVVIHVTAIYYGLILLCIFSYYLAGMPLFDAICHGMSAVSTGGFANYNDSIGHYNNPILE
AITIVFMILGSLPFLSYLKIIRRLDICYDEQVSYFVKIATISSLFACFWLYKNVDLGVSLSFRCSTFTITSLITSTGYAI
CNHIDWSFISVLAFFLTFVGGCSGSSSGGVKIFRLIIFLRSIENHFRLLLNPGAGDRVKFNGKTLENDEVHSVFIFFAIF
MLTFTISSIVMSYLSNADFITSISSVSATLTNSGPGFSNLIGPSGNYSSFSNEVKLFLSFLMLLGRLEILPIYFCIGNLF
LFNRKK
>Mature_486_residues
MKNHQRLQNLRSIVFIVGIFLLLFSLAMLIPAITNKCLSYKWKNFLAGFIITCTSGAIFILLGKLSRLHGMPAIFAITSC
TWIALSLFAAIPFYFDNLSYVDALFETISGITTTGATIFNDIEKQSPGILLWRAMLHGMGGFGVITLGIAVFPMFKVLSL
NNLLYSEYSDATKRKLPNTRSVVIHVTAIYYGLILLCIFSYYLAGMPLFDAICHGMSAVSTGGFANYNDSIGHYNNPILE
AITIVFMILGSLPFLSYLKIIRRLDICYDEQVSYFVKIATISSLFACFWLYKNVDLGVSLSFRCSTFTITSLITSTGYAI
CNHIDWSFISVLAFFLTFVGGCSGSSSGGVKIFRLIIFLRSIENHFRLLLNPGAGDRVKFNGKTLENDEVHSVFIFFAIF
MLTFTISSIVMSYLSNADFITSISSVSATLTNSGPGFSNLIGPSGNYSSFSNEVKLFLSFLMLLGRLEILPIYFCIGNLF
LFNRKK

Specific function: Low-affinity potassium transport system. Interacts with trk system potassium uptake protein trkA. TrkE increases the affinity of the system [H]

COG id: COG0168

COG function: function code P; Trk-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trkH potassium transport family [H]

Homologues:

Organism=Escherichia coli, GI1787626, Length=478, Percent_Identity=32.6359832635983, Blast_Score=204, Evalue=8e-54,
Organism=Escherichia coli, GI48994987, Length=479, Percent_Identity=28.39248434238, Blast_Score=144, Evalue=9e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003445
- InterPro:   IPR004772 [H]

Pfam domain/function: PF02386 TrkH [H]

EC number: NA

Molecular weight: Translated: 53978; Mature: 53978

Theoretical pI: Translated: 8.92; Mature: 8.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNHQRLQNLRSIVFIVGIFLLLFSLAMLIPAITNKCLSYKWKNFLAGFIITCTSGAIFI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
LLGKLSRLHGMPAIFAITSCTWIALSLFAAIPFYFDNLSYVDALFETISGITTTGATIFN
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHCCHHHHH
DIEKQSPGILLWRAMLHGMGGFGVITLGIAVFPMFKVLSLNNLLYSEYSDATKRKLPNTR
HHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
SVVIHVTAIYYGLILLCIFSYYLAGMPLFDAICHGMSAVSTGGFANYNDSIGHYNNPILE
HHEEHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCHHHHCCCCCCCCCCCCCCCCCHHHH
AITIVFMILGSLPFLSYLKIIRRLDICYDEQVSYFVKIATISSLFACFWLYKNVDLGVSL
HHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
SFRCSTFTITSLITSTGYAICNHIDWSFISVLAFFLTFVGGCSGSSSGGVKIFRLIIFLR
EEEEHHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHH
SIENHFRLLLNPGAGDRVKFNGKTLENDEVHSVFIFFAIFMLTFTISSIVMSYLSNADFI
HHHHHHEEEECCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
TSISSVSATLTNSGPGFSNLIGPSGNYSSFSNEVKLFLSFLMLLGRLEILPIYFCIGNLF
HHHHHHHHEECCCCCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFNRKK
HCCCCC
>Mature Secondary Structure
MKNHQRLQNLRSIVFIVGIFLLLFSLAMLIPAITNKCLSYKWKNFLAGFIITCTSGAIFI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
LLGKLSRLHGMPAIFAITSCTWIALSLFAAIPFYFDNLSYVDALFETISGITTTGATIFN
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHCCHHHHH
DIEKQSPGILLWRAMLHGMGGFGVITLGIAVFPMFKVLSLNNLLYSEYSDATKRKLPNTR
HHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
SVVIHVTAIYYGLILLCIFSYYLAGMPLFDAICHGMSAVSTGGFANYNDSIGHYNNPILE
HHEEHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCHHHHCCCCCCCCCCCCCCCCCHHHH
AITIVFMILGSLPFLSYLKIIRRLDICYDEQVSYFVKIATISSLFACFWLYKNVDLGVSL
HHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
SFRCSTFTITSLITSTGYAICNHIDWSFISVLAFFLTFVGGCSGSSSGGVKIFRLIIFLR
EEEEHHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHH
SIENHFRLLLNPGAGDRVKFNGKTLENDEVHSVFIFFAIFMLTFTISSIVMSYLSNADFI
HHHHHHEEEECCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
TSISSVSATLTNSGPGFSNLIGPSGNYSSFSNEVKLFLSFLMLLGRLEILPIYFCIGNLF
HHHHHHHHEECCCCCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFNRKK
HCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; K (I) [Periplasm] [C]

Specific reaction: Proton [Periplasm] + K (I) [Periplasm] = Proton [Cytoplasm] + K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2022616; 9097039; 9278503 [H]