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The map label for this gene is ileS [H]

Identifier: 225630139

GI number: 225630139

Start: 346431

End: 349742

Strand: Reverse

Name: ileS [H]

Synonym: WRi_003210

Alternate gene names: 225630139

Gene position: 349742-346431 (Counterclockwise)

Preceding gene: 225630141

Following gene: 225630138

Centisome position: 24.19

GC content: 36.81

Gene sequence:

>3312_bases
ATGAAGTCAAAGCATTATCCTGATACAGTAAGTAATCCTGATTTTTCGTCGTTAGAAAAGGAAATCATAAAATTTTGGCA
GGAAAATAAAGTTTTTGAGCAGTCAGTTGAAGAACGTTCCAAGGATAATTGTTTTGTCTTTTACGATGGGCCTCCGTTTG
CAAATGGACTTCCGCATTATGGACATTTACTCACTGGTTTCATCAAAGACGCATTTGCAAGATATCAAACTATGCTGCAA
AAAAGAGTCGAACGTAGATTTGGCTGGGATTGCCATGGATTACCGGCTGAGATGGGTGCAGAAAAAGAACTTGGAATATC
TGGTAGAACTGAAATAGAAAAATTTGGTATTGAAAAATTCAATAACCATTGCCGTACTTCTGTGATGAAATTTTCATCAG
AATGGGAAAAATATGTCAATAGACAAGCAAGATGGGTGGATTTTCACAATGACTATAAGACTATGGATAAATCATTCATG
GAGTCGGTCATGTGGGCATTTAAGCAGCTTTATGATAAGGGCTTAGTATATGAATCAGTACGCGTTGTTCCATATAGTTG
GGCTTGCGAAACTCCATTATCCAATTTTGAAACAAGGCTTGATAACGCGTATAGAGAAAAGACTAGCAAAGCTGTAACTG
TTGCATTTGAGCTTTTAGAAAACCCACAGCAATTTAAAAATATTGAACAAAAGTGCAAATTACTTGCTTGGACTACAACC
CCATGGACGTTGCCGAGCAATTTAGCTTTGGCGATAGGAAAGGACATCAAGTATTGTGCAGTGTCAGTCCACTCTTTGGC
AGCGCGTGAAGCTGGAATCCAGGAAGGTAATAAATGTTTGCATGCTGAAGTGACATCAAATCAACCTAATGAAATATATA
TCTTTGCTGAAAGTTACCTAGAGAAATTTATTAGCCACTCTGAACAAAACAATATTCCATATGAAAACTGCAATATAAAA
CTTAAAGCGAATGATCTTGCAGGTCTTTCTTACAAACCACTGTTTGACTATTTTAAAGACACAAAAAATGCATTTCGCGT
TTTTATTGCTGATTATGTTACAGGAGAAGACGGTACTGGCGTTGTGCATACTGCTCCTGGATTTGGTGAGGAAGATTTTT
ACCTTTGCCAAAGCCATGATATTCCAGTTATTTGTCCAATTGATAACAGTGGAAAATTTACTGCTGAAGTTTCAGATTTG
GCAGGGGTTCATGTTTTTGATGCCAATGATACAGTAATAAAAAAATTGAAAGGGCAGGGGAGTTGGTTTAAGACTGAGCA
ATATATTCACAATTATCCACACTGCTGGAGAACTGATACTCCTTTGATCTATCGCACTATGCCTTCTTGGTATGTTGCTG
TTACAAAATTCAAAAGCAGAATGGTAGAGCTAAATAAGAGAGTTAATTGGATACCAAACCACATTAGAGATGGTCAATTT
GGAAAATGGCTTGAAGGGGCACACGACTGGTCAATTTCACGCAATCGATTCTGGGGTACACCAATCCCTGTATGGAAATC
AGATGATGCGAGATATCCAAGAGTAGATGTATATGGTTCAATAGAAGAACTGGAAAGAGATTTTAATGTTAAAATAGACG
ACTTGCACAGACCATTTATCGATACTTTAACAAGACCAAATCCTGATGATCCAACAGGAAAATCAGTTATGCGCCGTGTA
CCTGACGTGTTTGACTGCTGGTTTGAATCTGGCTCGATGCCATTTGCGCAAATCCACTATCCGTTTGAAAATAAGGAGTG
GTTTGAATCTGCGGATTTTATCACTGAATACATAGCGCAAACCAGGGGGTGGTTTTATACGCTCTTTGTATTGTCCACTG
CTTTGTTTGATAGGGAACCATTTAAGAACTGCATATGCCACGGTGTTGTTTTGGATGTAAAAGGGCAAAAATTGTCCAAA
CGTTTGAATAACTATGCAGATCCAATGGAGGTTTTTGATAGATACGGTTCTGATGCACTGCGTTTTCTTATGCTTTCTGG
ATCTATTGTTTGTGGTGGTAATTTGCTACTCGATAAAGAAGGAAACTCAATACGAGATGTTCTGAAAAACGTAATAAAAC
CTATTTGGAATAGCTATCACTTTTTTACCATGTATGCAAATGCAGATGGGATTAAAGCTGAAGTTTGTAAGGATTATCAA
AGCACTATTGATCGTTACATGATTTCCAAGTGTTTTGAAGCTGTAGAAGGTATCCAAGCTTCTATGAACAACTATAACTC
CCAAGAGGCTTGCAAAATTTTAATGAACTTTTTTGAAGTGCTAAATAATTGGTATATTCGTCGCAGTCGCGAGCGTTTTT
GGAAAAGTGATTTGGATCAGGATAAAACTGATGCTTATAATGTTCTATATACGGTTTTTTATTACATACTAAGAGCTGCA
GCTCCTTTGTTGCCACTTATAACAGAGAATATATGGCAAGGGCTTAAGTATGAAGAAACATCTGTTCATTTGGCTAATTT
TCCACAATTAGAGAAGTTTGATAGTCAGCTCATTGCCAAGATGGATTTGGTGAGAGAGATATGCAACTCTGCACTCTCTA
TTAGAAACACTTTTAACATACGTATCAGACAGCCACTTGGCAGTATGATCATTTATCATCAGTCTTCCTGTAGTTTTCTT
GAAGGTGAGCCGTTTTCTGTCATCCCAGAGTTCTCTCCTGTTATCCAAGTAGCTGACACTGGGATCCAGTGTGCTGCAGA
TTCAAATGAGTACCAGGAGATGATAAAAGATGAGGTAAATGTAAAAAAACTGGAGTTAGTAAACAGACTTGAAGATATTG
CATCACTAGAGTTAAAGCTAAGTTTTCCGCTGCTTGGAAAGAGAATACCAGATAAAATTAAGAAACTAGTTCAATATGTC
AAAGAGGGAAAATGGAAGCAAGTTGAAAATGAGCAAGTTTTTTTAGGTAATGAGTCAGAAAATTACATCATAGAAAAAGG
CGAATATGAACTATTGTTAAAAGCAAATAGTGGATATTCTGCTGTGTTTGATAACAACAAAGGAGTTGTCATTCTAAATA
CTGAACTAAATGATGAATTAATTCTAGAAGGGTTAGCGAGAGATGTCGTGAGGCTCATTCAAGAAACCAGAAAACAAGCT
GATTTTCATATATCAGATAGAATCAGAGTAATAATCAAAACAGAAGATGAGAAAATTAAGGAAGCAATAAATACGTGGTT
TGAATATATAAAAGAGCAGACCCTTGCCTTATCTTTGGACATTAATACAGAAATTGGAACTAACTTCTATTCTAAGGAAT
ATCAGGATTTAAGTGTTAGTATTGAGCGTTAA

Upstream 100 bases:

>100_bases
AAGCTCGGCAGAATAGTTTGTTGGGGTGTGAGCTACGGAAATATTTTTGAATTTGTAATTTTTCAGAAAGCCCTATATTC
TTTAGTTTTACATAGCGAAC

Downstream 100 bases:

>100_bases
ATTTTTAATAAAGTTGCAAGATTGTCAGTATTTATGCTATACTTAAGGTAATTGGATAAGGTTATAATATGAATAAAGCT
GTTGCAGATGATTATGAAGA

Product: isoleucyl-tRNA synthetase

Products: NA

Alternate protein names: Isoleucine--tRNA ligase; IleRS [H]

Number of amino acids: Translated: 1103; Mature: 1103

Protein sequence:

>1103_residues
MKSKHYPDTVSNPDFSSLEKEIIKFWQENKVFEQSVEERSKDNCFVFYDGPPFANGLPHYGHLLTGFIKDAFARYQTMLQ
KRVERRFGWDCHGLPAEMGAEKELGISGRTEIEKFGIEKFNNHCRTSVMKFSSEWEKYVNRQARWVDFHNDYKTMDKSFM
ESVMWAFKQLYDKGLVYESVRVVPYSWACETPLSNFETRLDNAYREKTSKAVTVAFELLENPQQFKNIEQKCKLLAWTTT
PWTLPSNLALAIGKDIKYCAVSVHSLAAREAGIQEGNKCLHAEVTSNQPNEIYIFAESYLEKFISHSEQNNIPYENCNIK
LKANDLAGLSYKPLFDYFKDTKNAFRVFIADYVTGEDGTGVVHTAPGFGEEDFYLCQSHDIPVICPIDNSGKFTAEVSDL
AGVHVFDANDTVIKKLKGQGSWFKTEQYIHNYPHCWRTDTPLIYRTMPSWYVAVTKFKSRMVELNKRVNWIPNHIRDGQF
GKWLEGAHDWSISRNRFWGTPIPVWKSDDARYPRVDVYGSIEELERDFNVKIDDLHRPFIDTLTRPNPDDPTGKSVMRRV
PDVFDCWFESGSMPFAQIHYPFENKEWFESADFITEYIAQTRGWFYTLFVLSTALFDREPFKNCICHGVVLDVKGQKLSK
RLNNYADPMEVFDRYGSDALRFLMLSGSIVCGGNLLLDKEGNSIRDVLKNVIKPIWNSYHFFTMYANADGIKAEVCKDYQ
STIDRYMISKCFEAVEGIQASMNNYNSQEACKILMNFFEVLNNWYIRRSRERFWKSDLDQDKTDAYNVLYTVFYYILRAA
APLLPLITENIWQGLKYEETSVHLANFPQLEKFDSQLIAKMDLVREICNSALSIRNTFNIRIRQPLGSMIIYHQSSCSFL
EGEPFSVIPEFSPVIQVADTGIQCAADSNEYQEMIKDEVNVKKLELVNRLEDIASLELKLSFPLLGKRIPDKIKKLVQYV
KEGKWKQVENEQVFLGNESENYIIEKGEYELLLKANSGYSAVFDNNKGVVILNTELNDELILEGLARDVVRLIQETRKQA
DFHISDRIRVIIKTEDEKIKEAINTWFEYIKEQTLALSLDINTEIGTNFYSKEYQDLSVSIER

Sequences:

>Translated_1103_residues
MKSKHYPDTVSNPDFSSLEKEIIKFWQENKVFEQSVEERSKDNCFVFYDGPPFANGLPHYGHLLTGFIKDAFARYQTMLQ
KRVERRFGWDCHGLPAEMGAEKELGISGRTEIEKFGIEKFNNHCRTSVMKFSSEWEKYVNRQARWVDFHNDYKTMDKSFM
ESVMWAFKQLYDKGLVYESVRVVPYSWACETPLSNFETRLDNAYREKTSKAVTVAFELLENPQQFKNIEQKCKLLAWTTT
PWTLPSNLALAIGKDIKYCAVSVHSLAAREAGIQEGNKCLHAEVTSNQPNEIYIFAESYLEKFISHSEQNNIPYENCNIK
LKANDLAGLSYKPLFDYFKDTKNAFRVFIADYVTGEDGTGVVHTAPGFGEEDFYLCQSHDIPVICPIDNSGKFTAEVSDL
AGVHVFDANDTVIKKLKGQGSWFKTEQYIHNYPHCWRTDTPLIYRTMPSWYVAVTKFKSRMVELNKRVNWIPNHIRDGQF
GKWLEGAHDWSISRNRFWGTPIPVWKSDDARYPRVDVYGSIEELERDFNVKIDDLHRPFIDTLTRPNPDDPTGKSVMRRV
PDVFDCWFESGSMPFAQIHYPFENKEWFESADFITEYIAQTRGWFYTLFVLSTALFDREPFKNCICHGVVLDVKGQKLSK
RLNNYADPMEVFDRYGSDALRFLMLSGSIVCGGNLLLDKEGNSIRDVLKNVIKPIWNSYHFFTMYANADGIKAEVCKDYQ
STIDRYMISKCFEAVEGIQASMNNYNSQEACKILMNFFEVLNNWYIRRSRERFWKSDLDQDKTDAYNVLYTVFYYILRAA
APLLPLITENIWQGLKYEETSVHLANFPQLEKFDSQLIAKMDLVREICNSALSIRNTFNIRIRQPLGSMIIYHQSSCSFL
EGEPFSVIPEFSPVIQVADTGIQCAADSNEYQEMIKDEVNVKKLELVNRLEDIASLELKLSFPLLGKRIPDKIKKLVQYV
KEGKWKQVENEQVFLGNESENYIIEKGEYELLLKANSGYSAVFDNNKGVVILNTELNDELILEGLARDVVRLIQETRKQA
DFHISDRIRVIIKTEDEKIKEAINTWFEYIKEQTLALSLDINTEIGTNFYSKEYQDLSVSIER
>Mature_1103_residues
MKSKHYPDTVSNPDFSSLEKEIIKFWQENKVFEQSVEERSKDNCFVFYDGPPFANGLPHYGHLLTGFIKDAFARYQTMLQ
KRVERRFGWDCHGLPAEMGAEKELGISGRTEIEKFGIEKFNNHCRTSVMKFSSEWEKYVNRQARWVDFHNDYKTMDKSFM
ESVMWAFKQLYDKGLVYESVRVVPYSWACETPLSNFETRLDNAYREKTSKAVTVAFELLENPQQFKNIEQKCKLLAWTTT
PWTLPSNLALAIGKDIKYCAVSVHSLAAREAGIQEGNKCLHAEVTSNQPNEIYIFAESYLEKFISHSEQNNIPYENCNIK
LKANDLAGLSYKPLFDYFKDTKNAFRVFIADYVTGEDGTGVVHTAPGFGEEDFYLCQSHDIPVICPIDNSGKFTAEVSDL
AGVHVFDANDTVIKKLKGQGSWFKTEQYIHNYPHCWRTDTPLIYRTMPSWYVAVTKFKSRMVELNKRVNWIPNHIRDGQF
GKWLEGAHDWSISRNRFWGTPIPVWKSDDARYPRVDVYGSIEELERDFNVKIDDLHRPFIDTLTRPNPDDPTGKSVMRRV
PDVFDCWFESGSMPFAQIHYPFENKEWFESADFITEYIAQTRGWFYTLFVLSTALFDREPFKNCICHGVVLDVKGQKLSK
RLNNYADPMEVFDRYGSDALRFLMLSGSIVCGGNLLLDKEGNSIRDVLKNVIKPIWNSYHFFTMYANADGIKAEVCKDYQ
STIDRYMISKCFEAVEGIQASMNNYNSQEACKILMNFFEVLNNWYIRRSRERFWKSDLDQDKTDAYNVLYTVFYYILRAA
APLLPLITENIWQGLKYEETSVHLANFPQLEKFDSQLIAKMDLVREICNSALSIRNTFNIRIRQPLGSMIIYHQSSCSFL
EGEPFSVIPEFSPVIQVADTGIQCAADSNEYQEMIKDEVNVKKLELVNRLEDIASLELKLSFPLLGKRIPDKIKKLVQYV
KEGKWKQVENEQVFLGNESENYIIEKGEYELLLKANSGYSAVFDNNKGVVILNTELNDELILEGLARDVVRLIQETRKQA
DFHISDRIRVIIKTEDEKIKEAINTWFEYIKEQTLALSLDINTEIGTNFYSKEYQDLSVSIER

Specific function: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activi

COG id: COG0060

COG function: function code J; Isoleucyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily [H]

Homologues:

Organism=Homo sapiens, GI94721239, Length=1087, Percent_Identity=37.6264949402024, Blast_Score=720, Evalue=0.0,
Organism=Homo sapiens, GI94721241, Length=1087, Percent_Identity=37.6264949402024, Blast_Score=720, Evalue=0.0,
Organism=Homo sapiens, GI46852147, Length=856, Percent_Identity=27.4532710280374, Blast_Score=289, Evalue=1e-77,
Organism=Homo sapiens, GI268370293, Length=580, Percent_Identity=23.1034482758621, Blast_Score=108, Evalue=4e-23,
Organism=Homo sapiens, GI268370295, Length=580, Percent_Identity=23.1034482758621, Blast_Score=107, Evalue=4e-23,
Organism=Homo sapiens, GI268370297, Length=580, Percent_Identity=23.1034482758621, Blast_Score=107, Evalue=4e-23,
Organism=Homo sapiens, GI5454158, Length=603, Percent_Identity=22.3880597014925, Blast_Score=103, Evalue=1e-21,
Organism=Escherichia coli, GI2367096, Length=818, Percent_Identity=26.8948655256724, Blast_Score=299, Evalue=8e-82,
Organism=Escherichia coli, GI1790708, Length=724, Percent_Identity=20.8563535911602, Blast_Score=106, Evalue=8e-24,
Organism=Escherichia coli, GI1786861, Length=887, Percent_Identity=21.9842164599774, Blast_Score=101, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17541896, Length=1088, Percent_Identity=38.5110294117647, Blast_Score=719, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71980946, Length=849, Percent_Identity=25.6772673733804, Blast_Score=229, Evalue=7e-60,
Organism=Caenorhabditis elegans, GI17510661, Length=581, Percent_Identity=22.7194492254733, Blast_Score=130, Evalue=6e-30,
Organism=Caenorhabditis elegans, GI72001587, Length=217, Percent_Identity=27.1889400921659, Blast_Score=68, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6319395, Length=1124, Percent_Identity=36.8327402135231, Blast_Score=678, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6325217, Length=842, Percent_Identity=25.2969121140143, Blast_Score=227, Evalue=8e-60,
Organism=Saccharomyces cerevisiae, GI6321531, Length=912, Percent_Identity=22.4780701754386, Blast_Score=166, Evalue=2e-41,
Organism=Drosophila melanogaster, GI28574730, Length=1096, Percent_Identity=36.0401459854015, Blast_Score=674, Evalue=0.0,
Organism=Drosophila melanogaster, GI24668547, Length=1096, Percent_Identity=36.0401459854015, Blast_Score=674, Evalue=0.0,
Organism=Drosophila melanogaster, GI24668543, Length=1096, Percent_Identity=36.0401459854015, Blast_Score=674, Evalue=0.0,
Organism=Drosophila melanogaster, GI281366294, Length=800, Percent_Identity=27.125, Blast_Score=254, Evalue=2e-67,
Organism=Drosophila melanogaster, GI17864482, Length=936, Percent_Identity=21.7948717948718, Blast_Score=139, Evalue=1e-32,
Organism=Drosophila melanogaster, GI24653289, Length=936, Percent_Identity=21.7948717948718, Blast_Score=139, Evalue=1e-32,
Organism=Drosophila melanogaster, GI21355675, Length=563, Percent_Identity=20.7815275310835, Blast_Score=117, Evalue=4e-26,

Paralogues:

None

Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR002300
- InterPro:   IPR002301
- InterPro:   IPR014729
- InterPro:   IPR009080
- InterPro:   IPR013155
- InterPro:   IPR009008 [H]

Pfam domain/function: PF08264 Anticodon_1; PF00133 tRNA-synt_1 [H]

EC number: =6.1.1.5 [H]

Molecular weight: Translated: 128004; Mature: 128004

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSKHYPDTVSNPDFSSLEKEIIKFWQENKVFEQSVEERSKDNCFVFYDGPPFANGLPHY
CCCCCCCCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHCCCCCEEEEECCCCCCCCCCHH
GHLLTGFIKDAFARYQTMLQKRVERRFGWDCHGLPAEMGAEKELGISGRTEIEKFGIEKF
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHCCCCCCCCCCCCHHHHHHHHHHH
NNHCRTSVMKFSSEWEKYVNRQARWVDFHNDYKTMDKSFMESVMWAFKQLYDKGLVYESV
HHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCEECCE
RVVPYSWACETPLSNFETRLDNAYREKTSKAVTVAFELLENPQQFKNIEQKCKLLAWTTT
EEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHEEEEECC
PWTLPSNLALAIGKDIKYCAVSVHSLAAREAGIQEGNKCLHAEVTSNQPNEIYIFAESYL
CCCCCCCCEEEECCCCHHHHHHHHHHHHHHHCHHCCCCEEEEEECCCCCCEEEEEHHHHH
EKFISHSEQNNIPYENCNIKLKANDLAGLSYKPLFDYFKDTKNAFRVFIADYVTGEDGTG
HHHHHCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHEEHHHHHEECCCCCE
VVHTAPGFGEEDFYLCQSHDIPVICPIDNSGKFTAEVSDLAGVHVFDANDTVIKKLKGQG
EEECCCCCCCCCEEEEECCCCCEEEECCCCCCEEEEHHHCCCEEEECCCHHHHHHHCCCC
SWFKTEQYIHNYPHCWRTDTPLIYRTMPSWYVAVTKFKSRMVELNKRVNWIPNHIRDGQF
CCEEHHHHHHCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
GKWLEGAHDWSISRNRFWGTPIPVWKSDDARYPRVDVYGSIEELERDFNVKIDDLHRPFI
CHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCHHHHHHHCCCCHHHHCCHHH
DTLTRPNPDDPTGKSVMRRVPDVFDCWFESGSMPFAQIHYPFENKEWFESADFITEYIAQ
HHCCCCCCCCCCHHHHHHHCCHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHH
TRGWFYTLFVLSTALFDREPFKNCICHGVVLDVKGQKLSKRLNNYADPMEVFDRYGSDAL
HCCHHHHHHHHHHHHHCCCHHHHHHHCCEEEECCCHHHHHHHHCCCCHHHHHHHHCHHHH
RFLMLSGSIVCGGNLLLDKEGNSIRDVLKNVIKPIWNSYHFFTMYANADGIKAEVCKDYQ
HHHHHCCCEEECCEEEEECCCCHHHHHHHHHHHHHHCCEEEEEEEECCCCCHHHHHHHHH
STIDRYMISKCFEAVEGIQASMNNYNSQEACKILMNFFEVLNNWYIRRSRERFWKSDLDQ
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DKTDAYNVLYTVFYYILRAAAPLLPLITENIWQGLKYEETSVHLANFPQLEKFDSQLIAK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHH
MDLVREICNSALSIRNTFNIRIRQPLGSMIIYHQSSCSFLEGEPFSVIPEFSPVIQVADT
HHHHHHHHHHHHHHCCEEEEEEECCCCCEEEEECCCCCCCCCCCCEECCCCCHHHHHHCC
GIQCAADSNEYQEMIKDEVNVKKLELVNRLEDIASLELKLSFPLLGKRIPDKIKKLVQYV
CEEECCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHEEEEEECCHHCCCCHHHHHHHHHHH
KEGKWKQVENEQVFLGNESENYIIEKGEYELLLKANSGYSAVFDNNKGVVILNTELNDEL
HCCCCCCCCCCEEEECCCCCCEEEECCCEEEEEEECCCCEEEEECCCCEEEEECCCCHHH
ILEGLARDVVRLIQETRKQADFHISDRIRVIIKTEDEKIKEAINTWFEYIKEQTLALSLD
HHHHHHHHHHHHHHHHHHHCCCEECCCEEEEEECCHHHHHHHHHHHHHHHHCCEEEEEEE
INTEIGTNFYSKEYQDLSVSIER
CCCCCCCCHHHCCCCCCEEEECC
>Mature Secondary Structure
MKSKHYPDTVSNPDFSSLEKEIIKFWQENKVFEQSVEERSKDNCFVFYDGPPFANGLPHY
CCCCCCCCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHCCCCCEEEEECCCCCCCCCCHH
GHLLTGFIKDAFARYQTMLQKRVERRFGWDCHGLPAEMGAEKELGISGRTEIEKFGIEKF
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHCCCCCCCCCCCCHHHHHHHHHHH
NNHCRTSVMKFSSEWEKYVNRQARWVDFHNDYKTMDKSFMESVMWAFKQLYDKGLVYESV
HHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCEECCE
RVVPYSWACETPLSNFETRLDNAYREKTSKAVTVAFELLENPQQFKNIEQKCKLLAWTTT
EEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHEEEEECC
PWTLPSNLALAIGKDIKYCAVSVHSLAAREAGIQEGNKCLHAEVTSNQPNEIYIFAESYL
CCCCCCCCEEEECCCCHHHHHHHHHHHHHHHCHHCCCCEEEEEECCCCCCEEEEEHHHHH
EKFISHSEQNNIPYENCNIKLKANDLAGLSYKPLFDYFKDTKNAFRVFIADYVTGEDGTG
HHHHHCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHEEHHHHHEECCCCCE
VVHTAPGFGEEDFYLCQSHDIPVICPIDNSGKFTAEVSDLAGVHVFDANDTVIKKLKGQG
EEECCCCCCCCCEEEEECCCCCEEEECCCCCCEEEEHHHCCCEEEECCCHHHHHHHCCCC
SWFKTEQYIHNYPHCWRTDTPLIYRTMPSWYVAVTKFKSRMVELNKRVNWIPNHIRDGQF
CCEEHHHHHHCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
GKWLEGAHDWSISRNRFWGTPIPVWKSDDARYPRVDVYGSIEELERDFNVKIDDLHRPFI
CHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCHHHHHHHCCCCHHHHCCHHH
DTLTRPNPDDPTGKSVMRRVPDVFDCWFESGSMPFAQIHYPFENKEWFESADFITEYIAQ
HHCCCCCCCCCCHHHHHHHCCHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHH
TRGWFYTLFVLSTALFDREPFKNCICHGVVLDVKGQKLSKRLNNYADPMEVFDRYGSDAL
HCCHHHHHHHHHHHHHCCCHHHHHHHCCEEEECCCHHHHHHHHCCCCHHHHHHHHCHHHH
RFLMLSGSIVCGGNLLLDKEGNSIRDVLKNVIKPIWNSYHFFTMYANADGIKAEVCKDYQ
HHHHHCCCEEECCEEEEECCCCHHHHHHHHHHHHHHCCEEEEEEEECCCCCHHHHHHHHH
STIDRYMISKCFEAVEGIQASMNNYNSQEACKILMNFFEVLNNWYIRRSRERFWKSDLDQ
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DKTDAYNVLYTVFYYILRAAAPLLPLITENIWQGLKYEETSVHLANFPQLEKFDSQLIAK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHH
MDLVREICNSALSIRNTFNIRIRQPLGSMIIYHQSSCSFLEGEPFSVIPEFSPVIQVADT
HHHHHHHHHHHHHHCCEEEEEEECCCCCEEEEECCCCCCCCCCCCEECCCCCHHHHHHCC
GIQCAADSNEYQEMIKDEVNVKKLELVNRLEDIASLELKLSFPLLGKRIPDKIKKLVQYV
CEEECCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHEEEEEECCHHCCCCHHHHHHHHHHH
KEGKWKQVENEQVFLGNESENYIIEKGEYELLLKANSGYSAVFDNNKGVVILNTELNDEL
HCCCCCCCCCCEEEECCCCCCEEEECCCEEEEEEECCCCEEEEECCCCEEEEECCCCHHH
ILEGLARDVVRLIQETRKQADFHISDRIRVIIKTEDEKIKEAINTWFEYIKEQTLALSLD
HHHHHHHHHHHHHHHHHHHCCCEECCCEEEEEECCHHHHHHHHHHHHHHHHCCEEEEEEE
INTEIGTNFYSKEYQDLSVSIER
CCCCCCCCHHHCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA