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The map label for this gene is glmU [H]

Identifier: 225629972

GI number: 225629972

Start: 120589

End: 121881

Strand: Reverse

Name: glmU [H]

Synonym: WRi_001190

Alternate gene names: 225629972

Gene position: 121881-120589 (Counterclockwise)

Preceding gene: 225629973

Following gene: 225629971

Centisome position: 8.43

GC content: 36.35

Gene sequence:

>1293_bases
GTGATAAGTAAAACTCATACGTTCGTTATACTTGCTGCAGGGCATGGCAGGCGGATGAATTCAGATTTGCCTAAGGTCCT
ACACAAAATAGGCAATTTTTCCATGCTTCAGCATGTCATTTACAATGCAAAACAGTTAAATCCTGAAAATATTGCTGTTG
TAGTTGATCAGCCTTTAATTGAAAGACTAAAGTGCTTTGAGGATATACAGTTAATTACACAAGAATCAACACTCGGCACG
GGGGATGCAGTCAAAACTGCGATGAGAAACCTGAAAGAATTGCCAGATTCGAACATAGTTGTTGTGCAGTATGGAGATAC
TCCGCTCATAAAAAGCAGCACAATAACTAAAATGATTAGTTATTTAGAAGGCAAGGCTCTAGTTTGCCTAGGTTTTAGGG
CAAGCAATAAAGAATATGGTAGGTTAATCATTGAGAATGGTTCCTTAAGAGAAATCGTAGAAGCAAAGAGTGATAAAAAT
AATCATGAAGAGTTTCTTGCCAATGCTGGAATAATGGTTGCATATGCAAAGAATTTACGTGAATTGGTGGAGAAAATAGA
GTGCAATAGCTCAACTCATGAATATTATTTGACCGATATAGTTTCCATTGCAGTGAAGAGTAATTTAAATGTCGGTTACG
TTATTACGGGTGGAGAAGAAGCAACGGGAATAAATAACAGAAATGACCTTATAAAAGCTGAATTTTACTTTCAAGAAAAT
AAAAGAAAAATTTTTACCGACGCCGGAGTAACACTTGTTGCGCCAGAGACTGTTTTCTTTTCTCTTGATACGCAAATTGC
CAGAGATTCAGTTATTTACCCATATGTTTTTTTCGGTACTGGAGTGAAAATAGAGTCTGGTGCGAAAATACTGCCATTTT
CGCATTTAGAAAATTGCTTAATTAAAAGTAATGCTGAGGTCGGTCCATTTACCAGAATACGCGGAAACACAACAATTGGT
AATAAGGCAAAAATAGGAAATTTTGTGGAAGTGAAAACAAGTGAAGTTGGTCAAAACACTAGAATAAAACACTTAAGTTA
TATAGGAAATGCTAAAGTAGGGCAGGAGAGTAATATAGGAGCAGGCACTATTGTTTGTAATTATGATGGGAAAAATAAAC
ATGAAACGAATATAGGGAGCAATTGCTTTGTTGGCGCCAATAGCTCACTAATTGCGCCGCTTAATATTCATGATGAATCT
GTAATTGCAGCAGGTAGTGTTATAGTTGAGGATGTACCAGAAAAAAGCCTTGCAATAGCAAGAGAAAAGCAAGTAACTAA
GAGAATAAAGTAG

Upstream 100 bases:

>100_bases
TGCGATGCTAAAATATCAAATCAGCGACCTAAGAAGCTTTTACGATAACAAAATCAGCTGGCTTGATCATTACGGTTTTC
ATTTTTCATCTTTAAGATAA

Downstream 100 bases:

>100_bases
TCTAATTTAATTATGTTGTTGTGTCATTTTTAATATTAGACTTCTTGCATAACCATATAACAAACTTTTATTGGGAATAG
AAACAAAAAAACTTCCTTGA

Product: bifunctional protein GlmU

Products: NA

Alternate protein names: UDP-N-acetylglucosamine pyrophosphorylase; N-acetylglucosamine-1-phosphate uridyltransferase; Glucosamine-1-phosphate N-acetyltransferase [H]

Number of amino acids: Translated: 430; Mature: 430

Protein sequence:

>430_residues
MISKTHTFVILAAGHGRRMNSDLPKVLHKIGNFSMLQHVIYNAKQLNPENIAVVVDQPLIERLKCFEDIQLITQESTLGT
GDAVKTAMRNLKELPDSNIVVVQYGDTPLIKSSTITKMISYLEGKALVCLGFRASNKEYGRLIIENGSLREIVEAKSDKN
NHEEFLANAGIMVAYAKNLRELVEKIECNSSTHEYYLTDIVSIAVKSNLNVGYVITGGEEATGINNRNDLIKAEFYFQEN
KRKIFTDAGVTLVAPETVFFSLDTQIARDSVIYPYVFFGTGVKIESGAKILPFSHLENCLIKSNAEVGPFTRIRGNTTIG
NKAKIGNFVEVKTSEVGQNTRIKHLSYIGNAKVGQESNIGAGTIVCNYDGKNKHETNIGSNCFVGANSSLIAPLNIHDES
VIAAGSVIVEDVPEKSLAIAREKQVTKRIK

Sequences:

>Translated_430_residues
MISKTHTFVILAAGHGRRMNSDLPKVLHKIGNFSMLQHVIYNAKQLNPENIAVVVDQPLIERLKCFEDIQLITQESTLGT
GDAVKTAMRNLKELPDSNIVVVQYGDTPLIKSSTITKMISYLEGKALVCLGFRASNKEYGRLIIENGSLREIVEAKSDKN
NHEEFLANAGIMVAYAKNLRELVEKIECNSSTHEYYLTDIVSIAVKSNLNVGYVITGGEEATGINNRNDLIKAEFYFQEN
KRKIFTDAGVTLVAPETVFFSLDTQIARDSVIYPYVFFGTGVKIESGAKILPFSHLENCLIKSNAEVGPFTRIRGNTTIG
NKAKIGNFVEVKTSEVGQNTRIKHLSYIGNAKVGQESNIGAGTIVCNYDGKNKHETNIGSNCFVGANSSLIAPLNIHDES
VIAAGSVIVEDVPEKSLAIAREKQVTKRIK
>Mature_430_residues
MISKTHTFVILAAGHGRRMNSDLPKVLHKIGNFSMLQHVIYNAKQLNPENIAVVVDQPLIERLKCFEDIQLITQESTLGT
GDAVKTAMRNLKELPDSNIVVVQYGDTPLIKSSTITKMISYLEGKALVCLGFRASNKEYGRLIIENGSLREIVEAKSDKN
NHEEFLANAGIMVAYAKNLRELVEKIECNSSTHEYYLTDIVSIAVKSNLNVGYVITGGEEATGINNRNDLIKAEFYFQEN
KRKIFTDAGVTLVAPETVFFSLDTQIARDSVIYPYVFFGTGVKIESGAKILPFSHLENCLIKSNAEVGPFTRIRGNTTIG
NKAKIGNFVEVKTSEVGQNTRIKHLSYIGNAKVGQESNIGAGTIVCNYDGKNKHETNIGSNCFVGANSSLIAPLNIHDES
VIAAGSVIVEDVPEKSLAIAREKQVTKRIK

Specific function: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-GlcNAc. Responsible for the acetylation of Glc-N-1-P to give GlcNAc-1-P and for the uridyl transfer from UTP to GlcNAc-1-P which produces UDP-GlcNAc [H]

COG id: COG1207

COG function: function code M; N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Escherichia coli, GI1790168, Length=449, Percent_Identity=32.739420935412, Blast_Score=238, Evalue=6e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005882
- InterPro:   IPR005835
- InterPro:   IPR011004 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.23; =2.3.1.157 [H]

Molecular weight: Translated: 47271; Mature: 47271

Theoretical pI: Translated: 8.12; Mature: 8.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISKTHTFVILAAGHGRRMNSDLPKVLHKIGNFSMLQHVIYNAKQLNPENIAVVVDQPLI
CCCCEEEEEEEECCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHCCCCCCEEEEECCHHH
ERLKCFEDIQLITQESTLGTGDAVKTAMRNLKELPDSNIVVVQYGDTPLIKSSTITKMIS
HHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHH
YLEGKALVCLGFRASNKEYGRLIIENGSLREIVEAKSDKNNHEEFLANAGIMVAYAKNLR
HHCCCEEEEEEEECCCCCCCEEEEECCCHHHHHHHHCCCCCHHHHHHCCCEEEEHHHHHH
ELVEKIECNSSTHEYYLTDIVSIAVKSNLNVGYVITGGEEATGINNRNDLIKAEFYFQEN
HHHHHHHCCCCCCEEHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCEEEEEEEEECC
KRKIFTDAGVTLVAPETVFFSLDTQIARDSVIYPYVFFGTGVKIESGAKILPFSHLENCL
CEEEEECCCEEEEECCEEEEEECCHHHCCCEEEEEEEEECCEEECCCCEEECHHHHHHHH
IKSNAEVGPFTRIRGNTTIGNKAKIGNFVEVKTSEVGQNTRIKHLSYIGNAKVGQESNIG
CCCCCCCCCEEEECCCCCCCCCCCCCCEEEEEEHHCCCCCCEEEEEECCCCCCCCCCCCC
AGTIVCNYDGKNKHETNIGSNCFVGANSSLIAPLNIHDESVIAAGSVIVEDVPEKSLAIA
CEEEEEECCCCCCCCCCCCCEEEEECCCCEEEEEECCCCCEEEECCEEEECCCCHHHHHH
REKQVTKRIK
HHHHHHHHCC
>Mature Secondary Structure
MISKTHTFVILAAGHGRRMNSDLPKVLHKIGNFSMLQHVIYNAKQLNPENIAVVVDQPLI
CCCCEEEEEEEECCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHCCCCCCEEEEECCHHH
ERLKCFEDIQLITQESTLGTGDAVKTAMRNLKELPDSNIVVVQYGDTPLIKSSTITKMIS
HHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHH
YLEGKALVCLGFRASNKEYGRLIIENGSLREIVEAKSDKNNHEEFLANAGIMVAYAKNLR
HHCCCEEEEEEEECCCCCCCEEEEECCCHHHHHHHHCCCCCHHHHHHCCCEEEEHHHHHH
ELVEKIECNSSTHEYYLTDIVSIAVKSNLNVGYVITGGEEATGINNRNDLIKAEFYFQEN
HHHHHHHCCCCCCEEHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCEEEEEEEEECC
KRKIFTDAGVTLVAPETVFFSLDTQIARDSVIYPYVFFGTGVKIESGAKILPFSHLENCL
CEEEEECCCEEEEECCEEEEEECCHHHCCCEEEEEEEEECCEEECCCCEEECHHHHHHHH
IKSNAEVGPFTRIRGNTTIGNKAKIGNFVEVKTSEVGQNTRIKHLSYIGNAKVGQESNIG
CCCCCCCCCEEEECCCCCCCCCCCCCCEEEEEEHHCCCCCCEEEEEECCCCCCCCCCCCC
AGTIVCNYDGKNKHETNIGSNCFVGANSSLIAPLNIHDESVIAAGSVIVEDVPEKSLAIA
CEEEEEECCCCCCCCCCCCCEEEEECCCCEEEEEECCCCCEEEECCEEEECCCCHHHHHH
REKQVTKRIK
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA