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The map label for this gene is acoC [H]

Identifier: 222527135

GI number: 222527135

Start: 4867090

End: 4867866

Strand: Direct

Name: acoC [H]

Synonym: Chy400_3917

Alternate gene names: 222527135

Gene position: 4867090-4867866 (Clockwise)

Preceding gene: 222527134

Following gene: 222527136

Centisome position: 92.37

GC content: 61.65

Gene sequence:

>777_bases
ATGCCAGTTATCCAGGCCGGAGATATTGAGGTTCACTACCTTGACGTTGGTGAAGGCGAGCCGATTATCTTCGTGCACGG
CAATTGGGCCAGTTGCGGCTGGTGGCTACGGGTGCTCGAACGTCTCCCTGCCGGGTATCGTGGGCTGGCTCCCGATCTAC
GTGGTCGAGGCGCCACGCAGGGGCCAGACCACGACTACCGGATGCCCGCACTGGCCGCCGATCTGTGGCGTTTCGCCGAT
GCCCTCGGCATCCAACGCTGCCATCTGGTTGGACATTCGTTGGGGGCGGCGGTGGTCTTGCAGGCCGCACTCGATCAACC
TGATCGGGTAGCAACGATTGCCGTGCTGGCACCGCCATGGGTTGATGGCATGCCCGACGAGGTCTATCAACCAGATCGGC
AACAACTCTTGAAAGATAACCCTGATTTCTTTGCCCAGGCCATCAGGGCGATGGCACCAACCGCGCCAGATGACGAACTT
TGGCGCGAACTGGTGACTATCGGTCACTCGCAGCGGCTGAGTGCTGCCAACGGGGCAATCAATGCACTGCGTGAATGGAA
ACCCGGTGATCGTCTGCGCACGATTGGCGCCCCGGCACTGGTGATGGGTGGCGAACTCGATCCGTTGGTGACCCCGGAGA
CGGTGAAGCGGGCAGCCGAGGCCCTGGGGGTCGAGCCACAGATTATTGCCGGGGTCGGTCACTCGGCCAATCTCGAAGCA
CCGGATCGATTCCTGGCGCTGTTGTTGCCCCATCTGGCAACAGCACGCGCTTCCTGA

Upstream 100 bases:

>100_bases
GGTCATACGCCGTACATTGAGCATCCTGACCAGTTCAACGCTGCATTCCACGATCACCTGCGTAACAGGTAACAGGCTTG
AGCGGGAAAGTGAGAAAGCT

Downstream 100 bases:

>100_bases
AGAGGATGTGAGCATGCATGCACTGACAGCAGGTACCCGTTATCAACGGCAACATACGATCAGCCAGGAAGACATCAACC
GCTTTGCGGCGATTAGCGGC

Product: alpha/beta hydrolase fold protein

Products: NA

Alternate protein names: Acetoin dehydrogenase E2 component; Dihydrolipoamide acetyltransferase component of acetoin cleaving system; Fast-migrating protein; FMP [H]

Number of amino acids: Translated: 258; Mature: 257

Protein sequence:

>258_residues
MPVIQAGDIEVHYLDVGEGEPIIFVHGNWASCGWWLRVLERLPAGYRGLAPDLRGRGATQGPDHDYRMPALAADLWRFAD
ALGIQRCHLVGHSLGAAVVLQAALDQPDRVATIAVLAPPWVDGMPDEVYQPDRQQLLKDNPDFFAQAIRAMAPTAPDDEL
WRELVTIGHSQRLSAANGAINALREWKPGDRLRTIGAPALVMGGELDPLVTPETVKRAAEALGVEPQIIAGVGHSANLEA
PDRFLALLLPHLATARAS

Sequences:

>Translated_258_residues
MPVIQAGDIEVHYLDVGEGEPIIFVHGNWASCGWWLRVLERLPAGYRGLAPDLRGRGATQGPDHDYRMPALAADLWRFAD
ALGIQRCHLVGHSLGAAVVLQAALDQPDRVATIAVLAPPWVDGMPDEVYQPDRQQLLKDNPDFFAQAIRAMAPTAPDDEL
WRELVTIGHSQRLSAANGAINALREWKPGDRLRTIGAPALVMGGELDPLVTPETVKRAAEALGVEPQIIAGVGHSANLEA
PDRFLALLLPHLATARAS
>Mature_257_residues
PVIQAGDIEVHYLDVGEGEPIIFVHGNWASCGWWLRVLERLPAGYRGLAPDLRGRGATQGPDHDYRMPALAADLWRFADA
LGIQRCHLVGHSLGAAVVLQAALDQPDRVATIAVLAPPWVDGMPDEVYQPDRQQLLKDNPDFFAQAIRAMAPTAPDDELW
RELVTIGHSQRLSAANGAINALREWKPGDRLRTIGAPALVMGGELDPLVTPETVKRAAEALGVEPQIIAGVGHSANLEAP
DRFLALLLPHLATARAS

Specific function: Dihydrolipoamide acetyltransferase involved in acetoin catabolism [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 lipoyl-binding domain [H]

Homologues:

Organism=Homo sapiens, GI27597073, Length=123, Percent_Identity=30.8943089430894, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003016
- InterPro:   IPR000073
- InterPro:   IPR000089
- InterPro:   IPR011053 [H]

Pfam domain/function: PF00561 Abhydrolase_1; PF00364 Biotin_lipoyl [H]

EC number: =2.3.1.12 [H]

Molecular weight: Translated: 27901; Mature: 27770

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVIQAGDIEVHYLDVGEGEPIIFVHGNWASCGWWLRVLERLPAGYRGLAPDLRGRGATQ
CCCEECCCEEEEEEECCCCCEEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
GPDHDYRMPALAADLWRFADALGIQRCHLVGHSLGAAVVLQAALDQPDRVATIAVLAPPW
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCC
VDGMPDEVYQPDRQQLLKDNPDFFAQAIRAMAPTAPDDELWRELVTIGHSQRLSAANGAI
CCCCCHHHCCCCHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHHHHH
NALREWKPGDRLRTIGAPALVMGGELDPLVTPETVKRAAEALGVEPQIIAGVGHSANLEA
HHHHHCCCCCCEEECCCCEEEECCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCC
PDRFLALLLPHLATARAS
HHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PVIQAGDIEVHYLDVGEGEPIIFVHGNWASCGWWLRVLERLPAGYRGLAPDLRGRGATQ
CCEECCCEEEEEEECCCCCEEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
GPDHDYRMPALAADLWRFADALGIQRCHLVGHSLGAAVVLQAALDQPDRVATIAVLAPPW
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCC
VDGMPDEVYQPDRQQLLKDNPDFFAQAIRAMAPTAPDDELWRELVTIGHSQRLSAANGAI
CCCCCHHHCCCCHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHHHHH
NALREWKPGDRLRTIGAPALVMGGELDPLVTPETVKRAAEALGVEPQIIAGVGHSANLEA
HHHHHCCCCCCEEECCCCEEEECCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCC
PDRFLALLLPHLATARAS
HHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2061286 [H]