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The map label for this gene is corA [H]

Identifier: 222527038

GI number: 222527038

Start: 4754315

End: 4755280

Strand: Reverse

Name: corA [H]

Synonym: Chy400_3817

Alternate gene names: 222527038

Gene position: 4755280-4754315 (Counterclockwise)

Preceding gene: 222527039

Following gene: 222527037

Centisome position: 90.25

GC content: 51.86

Gene sequence:

>966_bases
ATGGTAACACTGCACACCTTTCAACGTCAACAGGTGCAACAGCTCACCGATTTCGATCAGATCAGCGAACTCCTTCTCCA
ACCACGCACCATGATCTGGCTCGATCTTGAACAACCGACAGACGCAGAGATTGCCCTGTTGCGCGAAGAGTTCGGTTTTC
ATCCGCTCGCGATTGAAGATGCGCTACAGATGCACGAACGACCGAAGATTGAAACCTACCCCGGTTACTACCTGATCATC
TTCTACAGCGTTGAATACGATGCGAAGCAGCGAACATTACAGTTTCTGCCGGTGGCGCTCTTTGTCGGGGCAAATTATCT
GGTCAGTATCCGCAGCGGCCCGGTGCGCCATGTGCAAGAGACGCTGGCGCGCTGGCAGAGTAATGGCTATATGCCGGGCT
ATCAGGTGAGCAGTATCCTCTACGCGCTGATTGATGCGATTGTTGACGATTACTTCGTCGCGCTGGATGCCCTCGGTGAA
CAGATTGATGACATCGAAGACGAGATTTTTCAACGCGGTCGCCACGAAGTAGCCAGTGACATCTTCACCCTGAAGAAAGA
CCTTCTGTTGCTACGGCGCATTGTCGCACCTGAGCGTGACATTCTGAATGTCCTATTGCGCCAGGAAGTGCGTATCTTCC
ACCCCCGTGAGTTAACCTACGTTCGCGATGTCTACGATCATCTGGTGCGGATCACCGAGTCGATTGATCTCTACCGCGAC
CTGCTCTCAAGTGCGCTGGATAGCTATCTTTCACTGCAAGGCAATCAACTCAATCAGTTGGTAAAGGTCTTAACCCTCTG
GTCGATTATTTTGATGTCCTGTTCACTGGTTGCCGGTATCTACGGGATGAACTTTGCGCTCATGCCCGAACTCGAACAGC
CGTGGGGGTATCCGTTTGCACTTGGTTTGATGCTAACTATTGCCGTTGGACTGGCAATTTACTTTAAACGGAGGCGCTGG
TGGTAG

Upstream 100 bases:

>100_bases
TCAAGCGATCATTCTCGCAAATACAAACGTTCATCTCGCTGTTCACTGTGCATTTTTCGGGGATGCGAAAATCTCTTTAT
CTAGGAAAGACCACAAATCG

Downstream 100 bases:

>100_bases
ATATACCACTACTGCTAATCGACGGTGTGCCACCGTCTGCCGCCATTATCATCGAACACCAGATAGTAGAATGGTCGTGT
TCTGTACCGGTCAATGCGAC

Product: magnesium and cobalt transport protein CorA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 321; Mature: 321

Protein sequence:

>321_residues
MVTLHTFQRQQVQQLTDFDQISELLLQPRTMIWLDLEQPTDAEIALLREEFGFHPLAIEDALQMHERPKIETYPGYYLII
FYSVEYDAKQRTLQFLPVALFVGANYLVSIRSGPVRHVQETLARWQSNGYMPGYQVSSILYALIDAIVDDYFVALDALGE
QIDDIEDEIFQRGRHEVASDIFTLKKDLLLLRRIVAPERDILNVLLRQEVRIFHPRELTYVRDVYDHLVRITESIDLYRD
LLSSALDSYLSLQGNQLNQLVKVLTLWSIILMSCSLVAGIYGMNFALMPELEQPWGYPFALGLMLTIAVGLAIYFKRRRW
W

Sequences:

>Translated_321_residues
MVTLHTFQRQQVQQLTDFDQISELLLQPRTMIWLDLEQPTDAEIALLREEFGFHPLAIEDALQMHERPKIETYPGYYLII
FYSVEYDAKQRTLQFLPVALFVGANYLVSIRSGPVRHVQETLARWQSNGYMPGYQVSSILYALIDAIVDDYFVALDALGE
QIDDIEDEIFQRGRHEVASDIFTLKKDLLLLRRIVAPERDILNVLLRQEVRIFHPRELTYVRDVYDHLVRITESIDLYRD
LLSSALDSYLSLQGNQLNQLVKVLTLWSIILMSCSLVAGIYGMNFALMPELEQPWGYPFALGLMLTIAVGLAIYFKRRRW
W
>Mature_321_residues
MVTLHTFQRQQVQQLTDFDQISELLLQPRTMIWLDLEQPTDAEIALLREEFGFHPLAIEDALQMHERPKIETYPGYYLII
FYSVEYDAKQRTLQFLPVALFVGANYLVSIRSGPVRHVQETLARWQSNGYMPGYQVSSILYALIDAIVDDYFVALDALGE
QIDDIEDEIFQRGRHEVASDIFTLKKDLLLLRRIVAPERDILNVLLRQEVRIFHPRELTYVRDVYDHLVRITESIDLYRD
LLSSALDSYLSLQGNQLNQLVKVLTLWSIILMSCSLVAGIYGMNFALMPELEQPWGYPFALGLMLTIAVGLAIYFKRRRW
W

Specific function: Mediates influx of magnesium ions [H]

COG id: COG0598

COG function: function code P; Mg2+ and Co2+ transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family [H]

Homologues:

Organism=Escherichia coli, GI1787604, Length=269, Percent_Identity=20.4460966542751, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI2367297, Length=308, Percent_Identity=24.025974025974, Blast_Score=67, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6324442, Length=317, Percent_Identity=23.3438485804416, Blast_Score=82, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6321058, Length=343, Percent_Identity=23.3236151603499, Blast_Score=80, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004488
- InterPro:   IPR002523 [H]

Pfam domain/function: PF01544 CorA [H]

EC number: NA

Molecular weight: Translated: 37408; Mature: 37408

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTLHTFQRQQVQQLTDFDQISELLLQPRTMIWLDLEQPTDAEIALLREEFGFHPLAIED
CCEEHHHHHHHHHHHHCHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHCCCCCHHHH
ALQMHERPKIETYPGYYLIIFYSVEYDAKQRTLQFLPVALFVGANYLVSIRSGPVRHVQE
HHHHHCCCCCCCCCCEEEEEEEEECCCHHHHHHHHHHHHHHHCCHHEEEECCCCHHHHHH
TLARWQSNGYMPGYQVSSILYALIDAIVDDYFVALDALGEQIDDIEDEIFQRGRHEVASD
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IFTLKKDLLLLRRIVAPERDILNVLLRQEVRIFHPRELTYVRDVYDHLVRITESIDLYRD
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LLSSALDSYLSLQGNQLNQLVKVLTLWSIILMSCSLVAGIYGMNFALMPELEQPWGYPFA
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCHHH
LGLMLTIAVGLAIYFKRRRWW
HHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVTLHTFQRQQVQQLTDFDQISELLLQPRTMIWLDLEQPTDAEIALLREEFGFHPLAIED
CCEEHHHHHHHHHHHHCHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHCCCCCHHHH
ALQMHERPKIETYPGYYLIIFYSVEYDAKQRTLQFLPVALFVGANYLVSIRSGPVRHVQE
HHHHHCCCCCCCCCCEEEEEEEEECCCHHHHHHHHHHHHHHHCCHHEEEECCCCHHHHHH
TLARWQSNGYMPGYQVSSILYALIDAIVDDYFVALDALGEQIDDIEDEIFQRGRHEVASD
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IFTLKKDLLLLRRIVAPERDILNVLLRQEVRIFHPRELTYVRDVYDHLVRITESIDLYRD
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LLSSALDSYLSLQGNQLNQLVKVLTLWSIILMSCSLVAGIYGMNFALMPELEQPWGYPFA
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCHHH
LGLMLTIAVGLAIYFKRRRWW
HHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]