Click here to switch to the map view.

The map label for this gene is ptrB [H]

Identifier: 222527030

GI number: 222527030

Start: 4741535

End: 4743571

Strand: Reverse

Name: ptrB [H]

Synonym: Chy400_3809

Alternate gene names: 222527030

Gene position: 4743571-4741535 (Counterclockwise)

Preceding gene: 222527031

Following gene: 222527029

Centisome position: 90.03

GC content: 56.5

Gene sequence:

>2037_bases
ATGCGCGTAGAGTTACCTCAACCTCCCGTGGCTGATCGTAAGCCGGTGGTGATCCGGATACAGGGTGATGAGATTGTTGA
TGAGTTTGCCTGGCTGGAAAACCGTGATGATCCCGCAGTGATTGCCTATCTTGAGGCGGAAAATGCGTATGCCGAAGCAG
TGATGGCGCCAGCCGCCGCCCTCCGTGAGCGCCTCTACCACGAGATGCGTGGTCGCATCAAAGAAGATGATCGCTCGGTG
CCGGTGCCGCATGGTCGTTATCGCTATTATTCACGCACGGAAAGTGGTGCCGAGTATCCACTGATGTGTCGTACTGAGGG
TGATGAGGGGCCGGAAGAGGTGCTGCTCGATCTGAACGCGCTGGCTGTCGGGCATGCGTTCTGTCGGCTTGGCCCATACG
AGCCTTCCCCGGATCATCGTCGTCTCGCCTATGGTATCGATACCACTGGTGCGATTATTTTTACGCTCTACATTAAAGAC
CTGACGACGGGTGATCTTATTGATGCGCCGATTGAACGGGTTGACAACGTGGCATGGGCTGATGAGCAGACACTGTTTTA
TACGGTATACGATGAGGCGCATCGTCCATACCGTCTCTATCGCCACGTTGTAGGTACGTCTCCCGCTGATGATGTGCTGG
TGTACGAAGAGACGGACGAGCGTTTCAATGTGAGTCTGCGCCGGAGTCGTTCGGGTGCGTATCTGTTTCTGACGTGCTAC
AGTCACGGTGGCACCGAGGTGCGGTATGTGCCGACGGCGACTCCGTTTGCTGAGTGGCGGGTGATCTATCCGCGCCGACC
GAAGATTGAGTACTTTGTCGATCATCACGGGGATCGGTTTTATATCAGGACGAATGATGGGGCCGAGAATTTTCGGCTGG
TGAGTGCGCCGGTAGACCATCCGACAGATGTGGTTGAGATTCTGCCGGAACGTGCCGATACGCTGATCGATGGTGTTACC
TGCTTCGCCGACTATCTTGTCGTCTATGAGCGACGGGCCGGGTTGCGTCAGATTCGGATTAGTGATCCGGATGGAAACAA
TCCGCGGTATGTTTCATTCCCCGAACCAGTCTATACCTGTACACCTGATGCAAATAAGGAATTCGTTACCGACCAGCTTC
GGCTATCGTACAGCTCGTTGGTCACGCCGCCGTCTATCGTCGCCTACGATATGCGTCGGGGAACCTGGCAGGTGCTGAAA
CAGGAAGAGATTCCTTCGGGCTACGATCCGTCGCTCTATGTCAGTGAGCGGCTTTGGGTTTCAGCACCGGATGGGGTGCA
GGTGCCGATGTCGATTGTCTATCGTCGCGACCGACCGCGGAACGGTGGCCCCTGTTTGCTGGTTGGGTATGGCGCGTATG
GCTACAGTTACGATCCTGCGTTCGACAGTAAGCGTTTGAGTCTGCTTGATCGCGGCTTTGTCGTGGCGATTGCCCATATT
CGTGGTGGGCAGGAGTTGGGGCGGCAGTGGTACGAACAGGGACGGATGCTCCACAAGCCGAACACGTTTAGCGATTTTAT
TGCCTGTGCGGAACATTTGATCAACGAGGGTTACACCTCGCCGTCACACCTGGCGATCAGTGGCCGCAGCGCCGGTGGGT
TGCTGATGAGTGCCGTGGTGAATGCCCGGCCTGACCTCTTCCAGGCCGTGGTAGCCGGCGTGCCCTTTACCAATGTGATT
ATCGCCATGCTCAAACCCGATCTGCCGCTGACCGCTACCGAATGGGAGCAATGGGGGAACCCGGCAATTGAGGAAGAATA
TCGGGTGATGCGCTCGTATGATCCGTACCTGAACCTGAAACCGGGTGCGTACCCGCATATCCTGGCGACCGCTGGTCTGC
ATGACCTTCAGGTGCCGTATTGGGACCCGGCCAAGTGGGTGGCAAAATTGCGCACCGTGAAGACAAATGACACGATGCTG
CTGTTGCGCACCAACCTTCAGGCCGGGCACAGCGGTCATTCGGGGCGGTTCGCCCGACTCGAAGAGTTTGCCTGGGAGTA
TGCGTTTATCTTAACCGCATTGGGCATCCATGCGTAG

Upstream 100 bases:

>100_bases
CGTCTCGATGATGCCGGGCATTATGTGTTAGAAGACGCTTCCGCTGAGATGATTGCGCTGCTGGCGCACTGGTTGTTGTC
AGAGTAAGAGGGGAATGTGT

Downstream 100 bases:

>100_bases
AGAAGCAGAGGTCAGGATGCGCAACGAAGAACAGACCGCTGCGCGCGTCACCTTCACAGTGGTGGCCGGCGCGAACGTTG
CCCGCCACCTGCCCTTGATG

Product: Oligopeptidase B

Products: NA

Alternate protein names: Oligopeptidase B; Protease II [H]

Number of amino acids: Translated: 678; Mature: 678

Protein sequence:

>678_residues
MRVELPQPPVADRKPVVIRIQGDEIVDEFAWLENRDDPAVIAYLEAENAYAEAVMAPAAALRERLYHEMRGRIKEDDRSV
PVPHGRYRYYSRTESGAEYPLMCRTEGDEGPEEVLLDLNALAVGHAFCRLGPYEPSPDHRRLAYGIDTTGAIIFTLYIKD
LTTGDLIDAPIERVDNVAWADEQTLFYTVYDEAHRPYRLYRHVVGTSPADDVLVYEETDERFNVSLRRSRSGAYLFLTCY
SHGGTEVRYVPTATPFAEWRVIYPRRPKIEYFVDHHGDRFYIRTNDGAENFRLVSAPVDHPTDVVEILPERADTLIDGVT
CFADYLVVYERRAGLRQIRISDPDGNNPRYVSFPEPVYTCTPDANKEFVTDQLRLSYSSLVTPPSIVAYDMRRGTWQVLK
QEEIPSGYDPSLYVSERLWVSAPDGVQVPMSIVYRRDRPRNGGPCLLVGYGAYGYSYDPAFDSKRLSLLDRGFVVAIAHI
RGGQELGRQWYEQGRMLHKPNTFSDFIACAEHLINEGYTSPSHLAISGRSAGGLLMSAVVNARPDLFQAVVAGVPFTNVI
IAMLKPDLPLTATEWEQWGNPAIEEEYRVMRSYDPYLNLKPGAYPHILATAGLHDLQVPYWDPAKWVAKLRTVKTNDTML
LLRTNLQAGHSGHSGRFARLEEFAWEYAFILTALGIHA

Sequences:

>Translated_678_residues
MRVELPQPPVADRKPVVIRIQGDEIVDEFAWLENRDDPAVIAYLEAENAYAEAVMAPAAALRERLYHEMRGRIKEDDRSV
PVPHGRYRYYSRTESGAEYPLMCRTEGDEGPEEVLLDLNALAVGHAFCRLGPYEPSPDHRRLAYGIDTTGAIIFTLYIKD
LTTGDLIDAPIERVDNVAWADEQTLFYTVYDEAHRPYRLYRHVVGTSPADDVLVYEETDERFNVSLRRSRSGAYLFLTCY
SHGGTEVRYVPTATPFAEWRVIYPRRPKIEYFVDHHGDRFYIRTNDGAENFRLVSAPVDHPTDVVEILPERADTLIDGVT
CFADYLVVYERRAGLRQIRISDPDGNNPRYVSFPEPVYTCTPDANKEFVTDQLRLSYSSLVTPPSIVAYDMRRGTWQVLK
QEEIPSGYDPSLYVSERLWVSAPDGVQVPMSIVYRRDRPRNGGPCLLVGYGAYGYSYDPAFDSKRLSLLDRGFVVAIAHI
RGGQELGRQWYEQGRMLHKPNTFSDFIACAEHLINEGYTSPSHLAISGRSAGGLLMSAVVNARPDLFQAVVAGVPFTNVI
IAMLKPDLPLTATEWEQWGNPAIEEEYRVMRSYDPYLNLKPGAYPHILATAGLHDLQVPYWDPAKWVAKLRTVKTNDTML
LLRTNLQAGHSGHSGRFARLEEFAWEYAFILTALGIHA
>Mature_678_residues
MRVELPQPPVADRKPVVIRIQGDEIVDEFAWLENRDDPAVIAYLEAENAYAEAVMAPAAALRERLYHEMRGRIKEDDRSV
PVPHGRYRYYSRTESGAEYPLMCRTEGDEGPEEVLLDLNALAVGHAFCRLGPYEPSPDHRRLAYGIDTTGAIIFTLYIKD
LTTGDLIDAPIERVDNVAWADEQTLFYTVYDEAHRPYRLYRHVVGTSPADDVLVYEETDERFNVSLRRSRSGAYLFLTCY
SHGGTEVRYVPTATPFAEWRVIYPRRPKIEYFVDHHGDRFYIRTNDGAENFRLVSAPVDHPTDVVEILPERADTLIDGVT
CFADYLVVYERRAGLRQIRISDPDGNNPRYVSFPEPVYTCTPDANKEFVTDQLRLSYSSLVTPPSIVAYDMRRGTWQVLK
QEEIPSGYDPSLYVSERLWVSAPDGVQVPMSIVYRRDRPRNGGPCLLVGYGAYGYSYDPAFDSKRLSLLDRGFVVAIAHI
RGGQELGRQWYEQGRMLHKPNTFSDFIACAEHLINEGYTSPSHLAISGRSAGGLLMSAVVNARPDLFQAVVAGVPFTNVI
IAMLKPDLPLTATEWEQWGNPAIEEEYRVMRSYDPYLNLKPGAYPHILATAGLHDLQVPYWDPAKWVAKLRTVKTNDTML
LLRTNLQAGHSGHSGRFARLEEFAWEYAFILTALGIHA

Specific function: Cleaves peptide bonds on the C-terminal side of lysyl and argininyl residues [H]

COG id: COG1770

COG function: function code E; Protease II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S9A family [H]

Homologues:

Organism=Homo sapiens, GI284172420, Length=565, Percent_Identity=29.2035398230088, Blast_Score=202, Evalue=8e-52,
Organism=Homo sapiens, GI284172413, Length=565, Percent_Identity=29.2035398230088, Blast_Score=202, Evalue=8e-52,
Organism=Homo sapiens, GI70778815, Length=565, Percent_Identity=29.2035398230088, Blast_Score=202, Evalue=8e-52,
Organism=Homo sapiens, GI284172438, Length=565, Percent_Identity=29.2035398230088, Blast_Score=202, Evalue=1e-51,
Organism=Homo sapiens, GI284172431, Length=565, Percent_Identity=29.2035398230088, Blast_Score=202, Evalue=1e-51,
Organism=Homo sapiens, GI41349456, Length=715, Percent_Identity=25.5944055944056, Blast_Score=194, Evalue=3e-49,
Organism=Homo sapiens, GI108860686, Length=561, Percent_Identity=28.5204991087344, Blast_Score=178, Evalue=1e-44,
Organism=Homo sapiens, GI108860692, Length=213, Percent_Identity=38.4976525821596, Blast_Score=143, Evalue=6e-34,
Organism=Escherichia coli, GI1788150, Length=672, Percent_Identity=41.3690476190476, Blast_Score=498, Evalue=1e-142,
Organism=Drosophila melanogaster, GI24583414, Length=717, Percent_Identity=26.4993026499303, Blast_Score=217, Evalue=2e-56,
Organism=Drosophila melanogaster, GI221510989, Length=700, Percent_Identity=26.2857142857143, Blast_Score=208, Evalue=1e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002471
- InterPro:   IPR001375
- InterPro:   IPR002470
- InterPro:   IPR004106 [H]

Pfam domain/function: PF00326 Peptidase_S9; PF02897 Peptidase_S9_N [H]

EC number: =3.4.21.83 [H]

Molecular weight: Translated: 76874; Mature: 76874

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVELPQPPVADRKPVVIRIQGDEIVDEFAWLENRDDPAVIAYLEAENAYAEAVMAPAAA
CCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHH
LRERLYHEMRGRIKEDDRSVPVPHGRYRYYSRTESGAEYPLMCRTEGDEGPEEVLLDLNA
HHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCEEEECCCCCCHHHHHHHHHH
LAVGHAFCRLGPYEPSPDHRRLAYGIDTTGAIIFTLYIKDLTTGDLIDAPIERVDNVAWA
HHHHHHHHHCCCCCCCCCCCEEEEECCCCCEEEEEEEEECCCCCCHHHHHHHHHCCCEEC
DEQTLFYTVYDEAHRPYRLYRHVVGTSPADDVLVYEETDERFNVSLRRSRSGAYLFLTCY
CCCEEEEEEECCCCCHHHHHHHHHCCCCCCCEEEEECCCCCEEEEEEECCCCCEEEEEEE
SHGGTEVRYVPTATPFAEWRVIYPRRPKIEYFVDHHGDRFYIRTNDGAENFRLVSAPVDH
CCCCCEEEEECCCCCCCCEEEECCCCCCEEEEEECCCCEEEEEECCCCCCEEEEECCCCC
PTDVVEILPERADTLIDGVTCFADYLVVYERRAGLRQIRISDPDGNNPRYVSFPEPVYTC
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCEEEECCCCEEEE
TPDANKEFVTDQLRLSYSSLVTPPSIVAYDMRRGTWQVLKQEEIPSGYDPSLYVSERLWV
CCCCCHHHHHHHHHHHHHHHCCCCHHEEECCCCCHHHHHHHHCCCCCCCCCEEEECEEEE
SAPDGVQVPMSIVYRRDRPRNGGPCLLVGYGAYGYSYDPAFDSKRLSLLDRGFVVAIAHI
ECCCCCCCCHHHEEECCCCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHCCCEEEEEEEC
RGGQELGRQWYEQGRMLHKPNTFSDFIACAEHLINEGYTSPSHLAISGRSAGGLLMSAVV
CCCHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHH
NARPDLFQAVVAGVPFTNVIIAMLKPDLPLTATEWEQWGNPAIEEEYRVMRSYDPYLNLK
HCCHHHHHHHHHCCCHHHHHHHHHCCCCCCCHHHHHHCCCCCHHHHHHHHHCCCCCEECC
PGAYPHILATAGLHDLQVPYWDPAKWVAKLRTVKTNDTMLLLRTNLQAGHSGHSGRFARL
CCCCCHHEEECCCCCCCCCCCCHHHHHHHHHEEECCCEEEEEEECCCCCCCCCCCCHHHH
EEFAWEYAFILTALGIHA
HHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRVELPQPPVADRKPVVIRIQGDEIVDEFAWLENRDDPAVIAYLEAENAYAEAVMAPAAA
CCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHH
LRERLYHEMRGRIKEDDRSVPVPHGRYRYYSRTESGAEYPLMCRTEGDEGPEEVLLDLNA
HHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCEEEECCCCCCHHHHHHHHHH
LAVGHAFCRLGPYEPSPDHRRLAYGIDTTGAIIFTLYIKDLTTGDLIDAPIERVDNVAWA
HHHHHHHHHCCCCCCCCCCCEEEEECCCCCEEEEEEEEECCCCCCHHHHHHHHHCCCEEC
DEQTLFYTVYDEAHRPYRLYRHVVGTSPADDVLVYEETDERFNVSLRRSRSGAYLFLTCY
CCCEEEEEEECCCCCHHHHHHHHHCCCCCCCEEEEECCCCCEEEEEEECCCCCEEEEEEE
SHGGTEVRYVPTATPFAEWRVIYPRRPKIEYFVDHHGDRFYIRTNDGAENFRLVSAPVDH
CCCCCEEEEECCCCCCCCEEEECCCCCCEEEEEECCCCEEEEEECCCCCCEEEEECCCCC
PTDVVEILPERADTLIDGVTCFADYLVVYERRAGLRQIRISDPDGNNPRYVSFPEPVYTC
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCEEEECCCCEEEE
TPDANKEFVTDQLRLSYSSLVTPPSIVAYDMRRGTWQVLKQEEIPSGYDPSLYVSERLWV
CCCCCHHHHHHHHHHHHHHHCCCCHHEEECCCCCHHHHHHHHCCCCCCCCCEEEECEEEE
SAPDGVQVPMSIVYRRDRPRNGGPCLLVGYGAYGYSYDPAFDSKRLSLLDRGFVVAIAHI
ECCCCCCCCHHHEEECCCCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHCCCEEEEEEEC
RGGQELGRQWYEQGRMLHKPNTFSDFIACAEHLINEGYTSPSHLAISGRSAGGLLMSAVV
CCCHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHH
NARPDLFQAVVAGVPFTNVIIAMLKPDLPLTATEWEQWGNPAIEEEYRVMRSYDPYLNLK
HCCHHHHHHHHHCCCHHHHHHHHHCCCCCCCHHHHHHCCCCCHHHHHHHHHCCCCCEECC
PGAYPHILATAGLHDLQVPYWDPAKWVAKLRTVKTNDTMLLLRTNLQAGHSGHSGRFARL
CCCCCHHEEECCCCCCCCCCCCHHHHHHHHHEEECCCEEEEEEECCCCCCCCCCCCHHHH
EEFAWEYAFILTALGIHA
HHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7629037 [H]