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The map label for this gene is cutS [H]

Identifier: 222526960

GI number: 222526960

Start: 4659833

End: 4660315

Strand: Reverse

Name: cutS [H]

Synonym: Chy400_3738

Alternate gene names: 222526960

Gene position: 4660315-4659833 (Counterclockwise)

Preceding gene: 222526961

Following gene: 222526959

Centisome position: 88.45

GC content: 55.49

Gene sequence:

>483_bases
GTGACAACGATTACGGTCACGGTCAATGGTGTTCGCCATACCAGCGAGGTCGAACCCCGCCTGCTGCTGGTTCATTACCT
GCGCGAGCATCTGAATCTGACGGGTACCCACATTGGGTGCGACACCAGCCAGTGTGGTGCGTGTGTGGTTCACATTAACG
GGGTCAGTGTGAAGTCGTGTACAACGTTGGCCGTTCAGTGTGATGGTGCCGAGATTACCACCATCGAAGGTCTGGCTCAG
GATGTTCAGTTGCACCCGTTGCAAGAAGGTTTCTGGGAGAAGCACGGCTTGCAATGTGGTTTCTGCACCCCTGGCATGAT
CATGGCTGCTGCCGATCTGCTCAAACGTAACCCCAATCCCTCCGAAGAAGAGATTCGCCACGGTCTTGAAGGTAATCTCT
GTCGCTGCACCGGGTACGAGAATATTGTCCGTGCCGTGCGCTACGCTGCCGAGAAGATGGCAGCAATGCAGGCCGCTGAT
TAA

Upstream 100 bases:

>100_bases
ACCTGATCGGGCGGCACCACTCACGACGCTGTCCCGCCGTTTTCGCCCGTCATAACATTAGTCTGGTTGTTCGTTTCGCA
GACAACGAGGAGGTTGGAGA

Downstream 100 bases:

>100_bases
TCCGTCCGACAGAAGTTCACACAGAACCTAGTGAGGAGTCAAGGATGACCGCTACCGAAATGAAGGAGCGATTGGTTGGA
CGGGCGCTCAAGCGCCGTGA

Product: (2Fe-2S)-binding domain-containing protein

Products: NA

Alternate protein names: CO dehydrogenase subunit S; CO-DH S [H]

Number of amino acids: Translated: 160; Mature: 159

Protein sequence:

>160_residues
MTTITVTVNGVRHTSEVEPRLLLVHYLREHLNLTGTHIGCDTSQCGACVVHINGVSVKSCTTLAVQCDGAEITTIEGLAQ
DVQLHPLQEGFWEKHGLQCGFCTPGMIMAAADLLKRNPNPSEEEIRHGLEGNLCRCTGYENIVRAVRYAAEKMAAMQAAD

Sequences:

>Translated_160_residues
MTTITVTVNGVRHTSEVEPRLLLVHYLREHLNLTGTHIGCDTSQCGACVVHINGVSVKSCTTLAVQCDGAEITTIEGLAQ
DVQLHPLQEGFWEKHGLQCGFCTPGMIMAAADLLKRNPNPSEEEIRHGLEGNLCRCTGYENIVRAVRYAAEKMAAMQAAD
>Mature_159_residues
TTITVTVNGVRHTSEVEPRLLLVHYLREHLNLTGTHIGCDTSQCGACVVHINGVSVKSCTTLAVQCDGAEITTIEGLAQD
VQLHPLQEGFWEKHGLQCGFCTPGMIMAAADLLKRNPNPSEEEIRHGLEGNLCRCTGYENIVRAVRYAAEKMAAMQAAD

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=159, Percent_Identity=37.7358490566038, Blast_Score=99, Evalue=2e-21,
Organism=Homo sapiens, GI71773480, Length=158, Percent_Identity=38.6075949367089, Blast_Score=90, Evalue=1e-18,
Organism=Escherichia coli, GI1786480, Length=167, Percent_Identity=42.5149700598802, Blast_Score=131, Evalue=2e-32,
Organism=Escherichia coli, GI1789232, Length=149, Percent_Identity=42.2818791946309, Blast_Score=111, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17540638, Length=171, Percent_Identity=42.1052631578947, Blast_Score=134, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI17539860, Length=156, Percent_Identity=37.1794871794872, Blast_Score=118, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI32566215, Length=157, Percent_Identity=36.3057324840764, Blast_Score=115, Evalue=1e-26,
Organism=Drosophila melanogaster, GI17737937, Length=165, Percent_Identity=36.3636363636364, Blast_Score=110, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24647193, Length=160, Percent_Identity=36.25, Blast_Score=99, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24647197, Length=163, Percent_Identity=35.5828220858896, Blast_Score=96, Evalue=9e-21,
Organism=Drosophila melanogaster, GI24647195, Length=163, Percent_Identity=35.5828220858896, Blast_Score=96, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24647201, Length=157, Percent_Identity=35.6687898089172, Blast_Score=96, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24647199, Length=166, Percent_Identity=33.7349397590361, Blast_Score=96, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 17403; Mature: 17272

Theoretical pI: Translated: 6.06; Mature: 6.06

Prosite motif: PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
8.8 %Cys+Met (Translated Protein)
5.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
8.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTITVTVNGVRHTSEVEPRLLLVHYLREHLNLTGTHIGCDTSQCGACVVHINGVSVKSC
CEEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCEECCCCCCCCEEEEEECCCEECCE
TTLAVQCDGAEITTIEGLAQDVQLHPLQEGFWEKHGLQCGFCTPGMIMAAADLLKRNPNP
EEEEEEECCCEEEEHHHHHHCCCCCCHHHHHHHHHCCEECCCCCHHHHHHHHHHHCCCCC
SEEEIRHGLEGNLCRCTGYENIVRAVRYAAEKMAAMQAAD
CHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TTITVTVNGVRHTSEVEPRLLLVHYLREHLNLTGTHIGCDTSQCGACVVHINGVSVKSC
EEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCEECCCCCCCCEEEEEECCCEECCE
TTLAVQCDGAEITTIEGLAQDVQLHPLQEGFWEKHGLQCGFCTPGMIMAAADLLKRNPNP
EEEEEEECCCEEEEHHHHHHCCCCCCHHHHHHHHHCCEECCCCCHHHHHHHHHHHCCCCC
SEEEIRHGLEGNLCRCTGYENIVRAVRYAAEKMAAMQAAD
CHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10482497; 2818128; 10966817; 11076018 [H]