Click here to switch to the map view.

The map label for this gene is cutL [H]

Identifier: 222526959

GI number: 222526959

Start: 4657425

End: 4659788

Strand: Reverse

Name: cutL [H]

Synonym: Chy400_3737

Alternate gene names: 222526959

Gene position: 4659788-4657425 (Counterclockwise)

Preceding gene: 222526960

Following gene: 222526958

Centisome position: 88.44

GC content: 58.38

Gene sequence:

>2364_bases
ATGACCGCTACCGAAATGAAGGAGCGATTGGTTGGACGGGCGCTCAAGCGCCGTGAGGATCCGAAGCTGATTACCGGCCA
CGGCAATTACCTCGACGACATCAAGCTGCCGGGAATGCTCCATATCGCGCTGGTGCGTAGCCCACACGCCCACGCGAAGA
TTGTCTCGATTGATGCCAGTCGCGCTCTGGCAATGCCGGGTGTTGTTGCGGTGTTCACCGGCAAGGATATGCTTGACATA
AATCCAATGCCGGCAGCATGGCAGGCGGCTGGGGTGAAGAATTATCCGGTTCCGCCACGTGCCCTGGCAGTCGATAAGGT
AGCACTTGTCGGTGATCCGGTGGCGATGGTGGTTGCCGAAGATCGGTATATTGCACGTGACGCTGCTGATGCAGTTGAGG
TCGAGTACGAGCCGCTGCCGGCAGTTGTCGATGCGCGTAAGGCGGTTGAACCCGGCGCCCCCCAGATTCACGAAGCAGCT
CCCAACAATATTGTGTTTGAATGGGAGTGTGGTAACAAGGCGGCAGCCGATGCGGCGATTGCCAGCGCTGAGGTGGTTGT
TAAGGAAGAGATTATCAACCAGCGCCTGATTCCCACCCCGATGGAGACTCGCGGTTCAATTGCCCGTTACGATGCTACGA
CCGGCGAGTGGACCGTCTGGATGACGTCGCAGGCTCCCCACGTGCACCGCCTGCTCTTAACGGCGTTTGTCTTCGGGGTG
CCGGAGACCAAGCTGCGCTGTATTGCGCCAAACGTGGGTGGTGGCTTCGGTCAGAAGATCTTCTGCTACAACGACATGGC
CTTCACCATGTGGGCTGCCCGTAAGCTGGGCCGTCCGGTGAAGTTCGTTGAAGATCGCTCTGAGAACTATAAGTATTCAA
CCCATGGTCGTGACCATATTACTGAAGCTGAGCTGGCCGGTACGCGCGACGGTAAGATTACCGGTCTGCGCGTGAAGACC
TGGGCAAATATCGGGGCGTACTTCTCGACCGTTGCCGCCGGTATTCCAACAACGCTTTACGGGCGCATTATTACCGGTGT
CTACAAGATTCCTGCCGCGTATGTCCACGTGACCGGTGCGTATACCAATACGGCAATGGTGGACGCTTACCGTGGTGCCG
GTCGCCCTGAAGCCAGCTATCTGATCGAGCGGATGGTTGACCGCTTCGCCGCCGAGATCGGGATGGATCCGGCTGAAGTG
CGCCGCAAAAACTATATTCAGCCTGAAGACTTCCCCTACGATAACGGTCTCGGTCTGCTACCCTACGACAGCGGCAATTA
CGAACCGGCCTTGAACAAGGCGCTCGAAATTGCCGGTTATGCCGAGTTCCGCAAGCAGCAGGAAGAGTTGCGCAAGCAGG
GCCGGTATCTCGGTATCGGCATCTCATCGTATGTTGAAATCTGTGGCATCGCCCCCAGCGCCTGGATGGGTGGTCAGGGT
TGGGGCGCCGGCCTCTGGGAGAGTGCGAATGTCCGTGTCCATCTGACCGGCAAGGTCGTGGTTACGACCGGTTCTCTCCC
CCACGGCCAGGGTCTTGAGACCACATTCGCCCAGATCGTCGCCGATGAGTTAGGTGTACCCTACGAAGATGTTGAAGTGC
AGTGGGGCGATACGCAAGGAACGCCATTCGGGTACGGCACCTACGGCTCACGCTCGCTGGCAGTCGGTGGGGTGGCGATT
AAGCGCAGCGTCGATAAGATTAAGGAGAAGGCGCGCAAACTGGCTGCTCACCTGTTGGAAGCGAATGAAGCGGACATCGT
CTTTGAAAATGGCCGGGCTTACGTCAAGGGTTCACCCGACAAGGCCAAGACGATTGGCGAACTCGCTGCGGCAGCGGCGG
TTGCTTACAACTTGCCACCTGGCATGGAGCCGTTCCTCGATGAGACCAGCTACTACGATCCGCCGAACTGCACCTTCCCG
TTCGGTACCCACGTGAGTATTGTCGAGGTCGATCCGGAGACCGGCCATGTCAAACTGCTGCGTTATATCGCGGTCGATGA
CTGTGGCAATCAGATCAATCCGCTGATTGTCGAAGGGCAGATCCACGGCGGTATTGCTCAGGGGCTGGCCCAGGCGCTCT
ATGAGGGTGCAGTCTACAACGAGGATGGCCAGTTGCTGACCGGTACGTTGATGGACTACGCAGTACCGACCGCGGCGATG
GTACCTCATATCGAAACCGACCACACCGTAACTCCGTCGCCGGTCAATCCACTGGGCGTCAAGGGTGCGGGTGAGGCCGG
AACGATTGCGTCGGCGCAGTGTGTGATGAACGCCATCATTGACGCACTGGCACCGTTTGGGGTGAAGCATCTCCAGATGC
CGGCAACGCCGGAACGCATCTGGAAGGCAATCCACGGGAAGTAG

Upstream 100 bases:

>100_bases
TCCGTGCCGTGCGCTACGCTGCCGAGAAGATGGCAGCAATGCAGGCCGCTGATTAATCCGTCCGACAGAAGTTCACACAG
AACCTAGTGAGGAGTCAAGG

Downstream 100 bases:

>100_bases
GTGTATGCCGGCAGGTGCAGGATTCCCCTGCGCCTGCTCACCATAAGGAGTAGCTATGATTCCAGCCCCATTTGATTACT
ATGCGCCAACCAGTCTGGCT

Product: molybdopterin binding aldehyde oxidase and xanthine dehydrogenase

Products: NA

Alternate protein names: CO dehydrogenase subunit L; CO-DH L [H]

Number of amino acids: Translated: 787; Mature: 786

Protein sequence:

>787_residues
MTATEMKERLVGRALKRREDPKLITGHGNYLDDIKLPGMLHIALVRSPHAHAKIVSIDASRALAMPGVVAVFTGKDMLDI
NPMPAAWQAAGVKNYPVPPRALAVDKVALVGDPVAMVVAEDRYIARDAADAVEVEYEPLPAVVDARKAVEPGAPQIHEAA
PNNIVFEWECGNKAAADAAIASAEVVVKEEIINQRLIPTPMETRGSIARYDATTGEWTVWMTSQAPHVHRLLLTAFVFGV
PETKLRCIAPNVGGGFGQKIFCYNDMAFTMWAARKLGRPVKFVEDRSENYKYSTHGRDHITEAELAGTRDGKITGLRVKT
WANIGAYFSTVAAGIPTTLYGRIITGVYKIPAAYVHVTGAYTNTAMVDAYRGAGRPEASYLIERMVDRFAAEIGMDPAEV
RRKNYIQPEDFPYDNGLGLLPYDSGNYEPALNKALEIAGYAEFRKQQEELRKQGRYLGIGISSYVEICGIAPSAWMGGQG
WGAGLWESANVRVHLTGKVVVTTGSLPHGQGLETTFAQIVADELGVPYEDVEVQWGDTQGTPFGYGTYGSRSLAVGGVAI
KRSVDKIKEKARKLAAHLLEANEADIVFENGRAYVKGSPDKAKTIGELAAAAAVAYNLPPGMEPFLDETSYYDPPNCTFP
FGTHVSIVEVDPETGHVKLLRYIAVDDCGNQINPLIVEGQIHGGIAQGLAQALYEGAVYNEDGQLLTGTLMDYAVPTAAM
VPHIETDHTVTPSPVNPLGVKGAGEAGTIASAQCVMNAIIDALAPFGVKHLQMPATPERIWKAIHGK

Sequences:

>Translated_787_residues
MTATEMKERLVGRALKRREDPKLITGHGNYLDDIKLPGMLHIALVRSPHAHAKIVSIDASRALAMPGVVAVFTGKDMLDI
NPMPAAWQAAGVKNYPVPPRALAVDKVALVGDPVAMVVAEDRYIARDAADAVEVEYEPLPAVVDARKAVEPGAPQIHEAA
PNNIVFEWECGNKAAADAAIASAEVVVKEEIINQRLIPTPMETRGSIARYDATTGEWTVWMTSQAPHVHRLLLTAFVFGV
PETKLRCIAPNVGGGFGQKIFCYNDMAFTMWAARKLGRPVKFVEDRSENYKYSTHGRDHITEAELAGTRDGKITGLRVKT
WANIGAYFSTVAAGIPTTLYGRIITGVYKIPAAYVHVTGAYTNTAMVDAYRGAGRPEASYLIERMVDRFAAEIGMDPAEV
RRKNYIQPEDFPYDNGLGLLPYDSGNYEPALNKALEIAGYAEFRKQQEELRKQGRYLGIGISSYVEICGIAPSAWMGGQG
WGAGLWESANVRVHLTGKVVVTTGSLPHGQGLETTFAQIVADELGVPYEDVEVQWGDTQGTPFGYGTYGSRSLAVGGVAI
KRSVDKIKEKARKLAAHLLEANEADIVFENGRAYVKGSPDKAKTIGELAAAAAVAYNLPPGMEPFLDETSYYDPPNCTFP
FGTHVSIVEVDPETGHVKLLRYIAVDDCGNQINPLIVEGQIHGGIAQGLAQALYEGAVYNEDGQLLTGTLMDYAVPTAAM
VPHIETDHTVTPSPVNPLGVKGAGEAGTIASAQCVMNAIIDALAPFGVKHLQMPATPERIWKAIHGK
>Mature_786_residues
TATEMKERLVGRALKRREDPKLITGHGNYLDDIKLPGMLHIALVRSPHAHAKIVSIDASRALAMPGVVAVFTGKDMLDIN
PMPAAWQAAGVKNYPVPPRALAVDKVALVGDPVAMVVAEDRYIARDAADAVEVEYEPLPAVVDARKAVEPGAPQIHEAAP
NNIVFEWECGNKAAADAAIASAEVVVKEEIINQRLIPTPMETRGSIARYDATTGEWTVWMTSQAPHVHRLLLTAFVFGVP
ETKLRCIAPNVGGGFGQKIFCYNDMAFTMWAARKLGRPVKFVEDRSENYKYSTHGRDHITEAELAGTRDGKITGLRVKTW
ANIGAYFSTVAAGIPTTLYGRIITGVYKIPAAYVHVTGAYTNTAMVDAYRGAGRPEASYLIERMVDRFAAEIGMDPAEVR
RKNYIQPEDFPYDNGLGLLPYDSGNYEPALNKALEIAGYAEFRKQQEELRKQGRYLGIGISSYVEICGIAPSAWMGGQGW
GAGLWESANVRVHLTGKVVVTTGSLPHGQGLETTFAQIVADELGVPYEDVEVQWGDTQGTPFGYGTYGSRSLAVGGVAIK
RSVDKIKEKARKLAAHLLEANEADIVFENGRAYVKGSPDKAKTIGELAAAAAVAYNLPPGMEPFLDETSYYDPPNCTFPF
GTHVSIVEVDPETGHVKLLRYIAVDDCGNQINPLIVEGQIHGGIAQGLAQALYEGAVYNEDGQLLTGTLMDYAVPTAAMV
PHIETDHTVTPSPVNPLGVKGAGEAGTIASAQCVMNAIIDALAPFGVKHLQMPATPERIWKAIHGK

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI71773480, Length=795, Percent_Identity=27.5471698113208, Blast_Score=204, Evalue=4e-52,
Organism=Homo sapiens, GI91823271, Length=799, Percent_Identity=25.7822277847309, Blast_Score=168, Evalue=1e-41,
Organism=Escherichia coli, GI1789230, Length=779, Percent_Identity=29.0115532734275, Blast_Score=249, Evalue=4e-67,
Organism=Escherichia coli, GI1789246, Length=829, Percent_Identity=26.7792521109771, Blast_Score=217, Evalue=3e-57,
Organism=Escherichia coli, GI1786478, Length=782, Percent_Identity=25.0639386189258, Blast_Score=124, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17540638, Length=798, Percent_Identity=25.31328320802, Blast_Score=167, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI17539860, Length=803, Percent_Identity=25.280199252802, Blast_Score=158, Evalue=9e-39,
Organism=Caenorhabditis elegans, GI32566215, Length=771, Percent_Identity=23.0869001297017, Blast_Score=107, Evalue=3e-23,
Organism=Drosophila melanogaster, GI17737937, Length=790, Percent_Identity=25.5696202531646, Blast_Score=162, Evalue=1e-39,
Organism=Drosophila melanogaster, GI24647193, Length=812, Percent_Identity=23.7684729064039, Blast_Score=120, Evalue=3e-27,
Organism=Drosophila melanogaster, GI24647201, Length=804, Percent_Identity=23.3830845771144, Blast_Score=102, Evalue=7e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274
- InterPro:   IPR012780 [H]

Pfam domain/function: PF01315 Ald_Xan_dh_C; PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 84986; Mature: 84855

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTATEMKERLVGRALKRREDPKLITGHGNYLDDIKLPGMLHIALVRSPHAHAKIVSIDAS
CCHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCEEEEEEEECCCCCEEEEEECCC
RALAMPGVVAVFTGKDMLDINPMPAAWQAAGVKNYPVPPRALAVDKVALVGDPVAMVVAE
CHHCCCCEEEEEECCCEEECCCCCCHHHHCCCCCCCCCCCHHHHCEEEECCCCEEEEEEC
DRYIARDAADAVEVEYEPLPAVVDARKAVEPGAPQIHEAAPNNIVFEWECGNKAAADAAI
CCEEHHCCCCCEEEECCCCCHHHHHHHHCCCCCCCHHHCCCCCEEEEEECCCCHHHHHHH
ASAEVVVKEEIINQRLIPTPMETRGSIARYDATTGEWTVWMTSQAPHVHRLLLTAFVFGV
HHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCEEEEEECCCCHHHHHHHHHHHHCC
PETKLRCIAPNVGGGFGQKIFCYNDMAFTMWAARKLGRPVKFVEDRSENYKYSTHGRDHI
CCCCEEEECCCCCCCCCCEEEEECCHHHHHHHHHHHCCCEEHHHCCCCCCEECCCCCCCC
TEAELAGTRDGKITGLRVKTWANIGAYFSTVAAGIPTTLYGRIITGVYKIPAAYVHVTGA
CHHHHCCCCCCCEEEEEEEEHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCEEEEEEECC
YTNTAMVDAYRGAGRPEASYLIERMVDRFAAEIGMDPAEVRRKNYIQPEDFPYDNGLGLL
CCCCEEEEHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCEEE
PYDSGNYEPALNKALEIAGYAEFRKQQEELRKQGRYLGIGISSYVEICGIAPSAWMGGQG
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHCCCCCCCCCCCC
WGAGLWESANVRVHLTGKVVVTTGSLPHGQGLETTFAQIVADELGVPYEDVEVQWGDTQG
CCCCCCCCCCEEEEEEEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCC
TPFGYGTYGSRSLAVGGVAIKRSVDKIKEKARKLAAHLLEANEADIVFENGRAYVKGSPD
CCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCEEEEECCCH
KAKTIGELAAAAAVAYNLPPGMEPFLDETSYYDPPNCTFPFGTHVSIVEVDPETGHVKLL
HHHHHHHHHHHHHHEECCCCCCCHHHCCCCCCCCCCCCCCCCCEEEEEEECCCCCCEEEE
RYIAVDDCGNQINPLIVEGQIHGGIAQGLAQALYEGAVYNEDGQLLTGTLMDYAVPTAAM
EEEEHHCCCCCCCCEEEEEEECCHHHHHHHHHHHCCCEECCCCCEEEHHHHHHHCCHHHH
VPHIETDHTVTPSPVNPLGVKGAGEAGTIASAQCVMNAIIDALAPFGVKHLQMPATPERI
CCCCCCCCEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHEEECCCCHHHH
WKAIHGK
HHHHCCC
>Mature Secondary Structure 
TATEMKERLVGRALKRREDPKLITGHGNYLDDIKLPGMLHIALVRSPHAHAKIVSIDAS
CHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCEEEEEEEECCCCCEEEEEECCC
RALAMPGVVAVFTGKDMLDINPMPAAWQAAGVKNYPVPPRALAVDKVALVGDPVAMVVAE
CHHCCCCEEEEEECCCEEECCCCCCHHHHCCCCCCCCCCCHHHHCEEEECCCCEEEEEEC
DRYIARDAADAVEVEYEPLPAVVDARKAVEPGAPQIHEAAPNNIVFEWECGNKAAADAAI
CCEEHHCCCCCEEEECCCCCHHHHHHHHCCCCCCCHHHCCCCCEEEEEECCCCHHHHHHH
ASAEVVVKEEIINQRLIPTPMETRGSIARYDATTGEWTVWMTSQAPHVHRLLLTAFVFGV
HHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCEEEEEECCCCHHHHHHHHHHHHCC
PETKLRCIAPNVGGGFGQKIFCYNDMAFTMWAARKLGRPVKFVEDRSENYKYSTHGRDHI
CCCCEEEECCCCCCCCCCEEEEECCHHHHHHHHHHHCCCEEHHHCCCCCCEECCCCCCCC
TEAELAGTRDGKITGLRVKTWANIGAYFSTVAAGIPTTLYGRIITGVYKIPAAYVHVTGA
CHHHHCCCCCCCEEEEEEEEHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCEEEEEEECC
YTNTAMVDAYRGAGRPEASYLIERMVDRFAAEIGMDPAEVRRKNYIQPEDFPYDNGLGLL
CCCCEEEEHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCEEE
PYDSGNYEPALNKALEIAGYAEFRKQQEELRKQGRYLGIGISSYVEICGIAPSAWMGGQG
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHCCCCCCCCCCCC
WGAGLWESANVRVHLTGKVVVTTGSLPHGQGLETTFAQIVADELGVPYEDVEVQWGDTQG
CCCCCCCCCCEEEEEEEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCC
TPFGYGTYGSRSLAVGGVAIKRSVDKIKEKARKLAAHLLEANEADIVFENGRAYVKGSPD
CCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCEEEEECCCH
KAKTIGELAAAAAVAYNLPPGMEPFLDETSYYDPPNCTFPFGTHVSIVEVDPETGHVKLL
HHHHHHHHHHHHHHEECCCCCCCHHHCCCCCCCCCCCCCCCCCEEEEEEECCCCCCEEEE
RYIAVDDCGNQINPLIVEGQIHGGIAQGLAQALYEGAVYNEDGQLLTGTLMDYAVPTAAM
EEEEHHCCCCCCCCEEEEEEECCHHHHHHHHHHHCCCEECCCCCEEEHHHHHHHCCHHHH
VPHIETDHTVTPSPVNPLGVKGAGEAGTIASAQCVMNAIIDALAPFGVKHLQMPATPERI
CCCCCCCCEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHEEECCCCHHHH
WKAIHGK
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10482497; 2818128; 10966817; 11076018 [H]