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The map label for this gene is rsbRA [H]

Identifier: 222526947

GI number: 222526947

Start: 4643281

End: 4644222

Strand: Reverse

Name: rsbRA [H]

Synonym: Chy400_3725

Alternate gene names: 222526947

Gene position: 4644222-4643281 (Counterclockwise)

Preceding gene: 222526948

Following gene: 222526946

Centisome position: 88.14

GC content: 56.05

Gene sequence:

>942_bases
ATGATCCGCCTCACACAGCAACAGATCAACCACGGCGTTTTTGGCTTCCTTACCGGATTGGCCGTCATTGCACTTTTTCT
TGCATTCTTTCCCGAACCACTATTGTCAACCATTGTGTCAGTGCTTGCAGGTCTGGTTATTAGCGGTGGCCTGTGGTTTG
CCTACTGGCGTGGGTGGGAGCCGGCACGTCCATTGCTGATCATTCTACTCACGGTGATTGTCGCATTTGGAACCGATGAA
ATATTCATTGATGCACGATTCCATCATTTGCTCTACACTATTCCGGCACTGGCACTGGTGTTGACCAGTCCATTCTGGAT
TGCAGCAAGCGCACTAACACTACTGGTCACATTTGCTTACCGGGCGGGTGGTGGTCCCTATGTCAATCCTTTCGAGCTGG
TAACGTTTGCGTTTATCGTCGGCGGCATGATCTTCAGTCGTTTGGCGATTGATAATGCTCAGCACCTGGAGGCGGCAAGA
CGCGAGGCAGAAGAAGCCCGTGCGTGGGCTGAACAACGGGAACACGAACTGGCTGCGCAGGCGGAAGAGCTGGCGCAACG
TAACACCGAACAGCAACGGTTGCTCGAACTGGTATCCGTGCTTGAGACACCAACCATCACGCTGGCGGAGGGTGTGCTGA
TGGCCCCGATTGTGGGCGCACTCGATAGCCGACGTGCTCAGGCGCTAACGACGCGCCTGCTTCAAGAAGCCAATGCCCGG
CGTGCCCGTCGTGTCATTCTCGACATCAGTGGGGTGAGCGCAGTTGACACCCAGGTTGCGCAGGCGCTGATCCAGACTGC
GCGGGCGCTGCGTCTGCTCGGTTGCCAGGTGATCCTTACCGGTATTTCGGCCACGGTAGCAATGACGCTCACGCATCTGA
ATGTGGCTATGGAAGGTATGATAACGACCCGCTCGCCGCAAGAGGCGCTGGCAATGCAGTAG

Upstream 100 bases:

>100_bases
CTGAAGTTGTGCAATCAATTGTTGGCCTTGGTGTGCATTTGAATGGTATTCGTTCGTTTAGTGACCTGCAGAGCGCTCTG
AAATTGTCAGGAGATCAGGG

Downstream 100 bases:

>100_bases
CAGCAACATCTGGAACGCGAGGGGGGCGCTGAGGTCATTGCACCACAGAGGCACTGAGAACACAGAGATGGCGGATGTAT
GCCTTGTTTCCGTTCGGTAG

Product: anti-sigma-factor antagonist

Products: NA

Alternate protein names: Stressosome protein rsbRA [H]

Number of amino acids: Translated: 313; Mature: 313

Protein sequence:

>313_residues
MIRLTQQQINHGVFGFLTGLAVIALFLAFFPEPLLSTIVSVLAGLVISGGLWFAYWRGWEPARPLLIILLTVIVAFGTDE
IFIDARFHHLLYTIPALALVLTSPFWIAASALTLLVTFAYRAGGGPYVNPFELVTFAFIVGGMIFSRLAIDNAQHLEAAR
REAEEARAWAEQREHELAAQAEELAQRNTEQQRLLELVSVLETPTITLAEGVLMAPIVGALDSRRAQALTTRLLQEANAR
RARRVILDISGVSAVDTQVAQALIQTARALRLLGCQVILTGISATVAMTLTHLNVAMEGMITTRSPQEALAMQ

Sequences:

>Translated_313_residues
MIRLTQQQINHGVFGFLTGLAVIALFLAFFPEPLLSTIVSVLAGLVISGGLWFAYWRGWEPARPLLIILLTVIVAFGTDE
IFIDARFHHLLYTIPALALVLTSPFWIAASALTLLVTFAYRAGGGPYVNPFELVTFAFIVGGMIFSRLAIDNAQHLEAAR
REAEEARAWAEQREHELAAQAEELAQRNTEQQRLLELVSVLETPTITLAEGVLMAPIVGALDSRRAQALTTRLLQEANAR
RARRVILDISGVSAVDTQVAQALIQTARALRLLGCQVILTGISATVAMTLTHLNVAMEGMITTRSPQEALAMQ
>Mature_313_residues
MIRLTQQQINHGVFGFLTGLAVIALFLAFFPEPLLSTIVSVLAGLVISGGLWFAYWRGWEPARPLLIILLTVIVAFGTDE
IFIDARFHHLLYTIPALALVLTSPFWIAASALTLLVTFAYRAGGGPYVNPFELVTFAFIVGGMIFSRLAIDNAQHLEAAR
REAEEARAWAEQREHELAAQAEELAQRNTEQQRLLELVSVLETPTITLAEGVLMAPIVGALDSRRAQALTTRLLQEANAR
RARRVILDISGVSAVDTQVAQALIQTARALRLLGCQVILTGISATVAMTLTHLNVAMEGMITTRSPQEALAMQ

Specific function: Negative regulator of sigma-B activity. Non- phosphorylated rsbS binds to rsbT, preventing its association with rsbU. Requires any one of rsbRA, rsbRB, rsbRC or rsbRD to sequester rsbT. When rsbS and the rsbR paralog(s) are phosphorylated, they release rs

COG id: COG1366

COG function: function code T; Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014792
- InterPro:   IPR002645 [H]

Pfam domain/function: PF08678 Rsbr_N; PF01740 STAS [H]

EC number: NA

Molecular weight: Translated: 34208; Mature: 34208

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRLTQQQINHGVFGFLTGLAVIALFLAFFPEPLLSTIVSVLAGLVISGGLWFAYWRGWE
CCCCCHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHCCCC
PARPLLIILLTVIVAFGTDEIFIDARFHHLLYTIPALALVLTSPFWIAASALTLLVTFAY
CCHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
RAGGGPYVNPFELVTFAFIVGGMIFSRLAIDNAQHLEAARREAEEARAWAEQREHELAAQ
HCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AEELAQRNTEQQRLLELVSVLETPTITLAEGVLMAPIVGALDSRRAQALTTRLLQEANAR
HHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RARRVILDISGVSAVDTQVAQALIQTARALRLLGCQVILTGISATVAMTLTHLNVAMEGM
HHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ITTRSPQEALAMQ
HCCCCHHHHHCCC
>Mature Secondary Structure
MIRLTQQQINHGVFGFLTGLAVIALFLAFFPEPLLSTIVSVLAGLVISGGLWFAYWRGWE
CCCCCHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHCCCC
PARPLLIILLTVIVAFGTDEIFIDARFHHLLYTIPALALVLTSPFWIAASALTLLVTFAY
CCHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
RAGGGPYVNPFELVTFAFIVGGMIFSRLAIDNAQHLEAARREAEEARAWAEQREHELAAQ
HCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AEELAQRNTEQQRLLELVSVLETPTITLAEGVLMAPIVGALDSRRAQALTTRLLQEANAR
HHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RARRVILDISGVSAVDTQVAQALIQTARALRLLGCQVILTGISATVAMTLTHLNVAMEGM
HHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ITTRSPQEALAMQ
HCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8002610; 9384377; 11157946; 10329124 [H]