Click here to switch to the map view.

The map label for this gene is argC [H]

Identifier: 222526939

GI number: 222526939

Start: 4636924

End: 4637925

Strand: Reverse

Name: argC [H]

Synonym: Chy400_3717

Alternate gene names: 222526939

Gene position: 4637925-4636924 (Counterclockwise)

Preceding gene: 222526940

Following gene: 222526938

Centisome position: 88.02

GC content: 60.38

Gene sequence:

>1002_bases
ATGGCCCGTGTCGGTATCTATGGCGCAACCGGGTACACCGGGATTGAGCTGATCAAACTGCTCTCCCGCCACCCGGAGGT
TGAGATAGGCTTTGCAACCGCTCGCTCTGCTGCCGGGCAGCGCCTGAGCGAGGTCTTTCCGATCCTGAGCGATCTGCGAT
TGACCGCGGTGGAGGAGGTCGATCCGGCGACGGTTGATCTCGTCTTTACCTGTCTCCCCCACAACACCCCCGATTTGATT
CCCATCGTGCAACGAGCGCTGGCTGCGGGTGCCAGAGTGGTCGATTTCTCCGACACCTTTCGCATCAGTGATCCGCAGGT
CTACGCTGCGCGGCGCGGAAAGGAACATCCGGCACCGGAGTTGCTCGCCCAGGCCGTGTATGGATTGCCTGAGCTGCATC
GCGAGCGAATCCGGCAAGCGCGGTTGGTTGCCAATACCGGCTGTTACCCATTGACCGCCATTCTGCCGCTGGTGCCACTG
GTGCGCGCCGATCTGCTCGCCGACTCGACGGTGATTGTTGATAGTAAGTCAGGCGTCTCTGGCGCCGGTCGCTCGCTGTC
GCTCAAGACCCACTTCGGCGAAACCCACGAAACGTTCAGTGCCTACAATGTTGGGCGTGTCCATCGCCATCTGGCCGAAA
TGGAGCAGGAGACCGGCCTGCATATCATCTTCGCCCCCCATCTCCTGCCGGTCTTCCGTGGCATCCTTTCGACAATTTAT
GTCAACTTAAAGCCGGGGGTTGACGAGGCAACGCTGGCCGCAGTCTATGCCGATGCCTATGCGGCTGAGCCTTTCGTCCA
TGTCTTGCCGGGCGGACGGTTGCCGGAGCTGCGCCACGTGCAACACACGAATCACGTGGTGATCGGTTATCAGATGGTTG
AGCCAGGGCGGGCGATTCTGGTGGCTGTGATCGATAATCTGGTGAAGGGGGCCGCCGGTCAGGCAGTGCAGAATATGAAT
TTGCTGCTGGGGTTTGCTGAGACGGTGGGGTTGATGGGGTAG

Upstream 100 bases:

>100_bases
ATTCACCCGGCTGTGATCGCTATCGCGCCTGATCGCACGTGGTAGAGAGTACGGTACAATGAACGAGATGGTATTCGTTC
ATTGAACAAGGAGCGCACCA

Downstream 100 bases:

>100_bases
GGGCAGGTTATATGTCTACCTGCCCTGTACAGCGACGCTGAAACTATGAAGACACCGATAGCATACCATCCACAACGGAG
AGAGGTCCTGCCGTTCGATG

Product: N-acetyl-gamma-glutamyl-phosphate reductase

Products: NA

Alternate protein names: AGPR; N-acetyl-glutamate semialdehyde dehydrogenase; NAGSA dehydrogenase [H]

Number of amino acids: Translated: 333; Mature: 332

Protein sequence:

>333_residues
MARVGIYGATGYTGIELIKLLSRHPEVEIGFATARSAAGQRLSEVFPILSDLRLTAVEEVDPATVDLVFTCLPHNTPDLI
PIVQRALAAGARVVDFSDTFRISDPQVYAARRGKEHPAPELLAQAVYGLPELHRERIRQARLVANTGCYPLTAILPLVPL
VRADLLADSTVIVDSKSGVSGAGRSLSLKTHFGETHETFSAYNVGRVHRHLAEMEQETGLHIIFAPHLLPVFRGILSTIY
VNLKPGVDEATLAAVYADAYAAEPFVHVLPGGRLPELRHVQHTNHVVIGYQMVEPGRAILVAVIDNLVKGAAGQAVQNMN
LLLGFAETVGLMG

Sequences:

>Translated_333_residues
MARVGIYGATGYTGIELIKLLSRHPEVEIGFATARSAAGQRLSEVFPILSDLRLTAVEEVDPATVDLVFTCLPHNTPDLI
PIVQRALAAGARVVDFSDTFRISDPQVYAARRGKEHPAPELLAQAVYGLPELHRERIRQARLVANTGCYPLTAILPLVPL
VRADLLADSTVIVDSKSGVSGAGRSLSLKTHFGETHETFSAYNVGRVHRHLAEMEQETGLHIIFAPHLLPVFRGILSTIY
VNLKPGVDEATLAAVYADAYAAEPFVHVLPGGRLPELRHVQHTNHVVIGYQMVEPGRAILVAVIDNLVKGAAGQAVQNMN
LLLGFAETVGLMG
>Mature_332_residues
ARVGIYGATGYTGIELIKLLSRHPEVEIGFATARSAAGQRLSEVFPILSDLRLTAVEEVDPATVDLVFTCLPHNTPDLIP
IVQRALAAGARVVDFSDTFRISDPQVYAARRGKEHPAPELLAQAVYGLPELHRERIRQARLVANTGCYPLTAILPLVPLV
RADLLADSTVIVDSKSGVSGAGRSLSLKTHFGETHETFSAYNVGRVHRHLAEMEQETGLHIIFAPHLLPVFRGILSTIYV
NLKPGVDEATLAAVYADAYAAEPFVHVLPGGRLPELRHVQHTNHVVIGYQMVEPGRAILVAVIDNLVKGAAGQAVQNMNL
LLGFAETVGLMG

Specific function: Arginine biosynthesis; third step. [C]

COG id: COG0002

COG function: function code E; Acetylglutamate semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790396, Length=343, Percent_Identity=39.9416909620991, Blast_Score=187, Evalue=7e-49,
Organism=Saccharomyces cerevisiae, GI6320913, Length=342, Percent_Identity=29.5321637426901, Blast_Score=120, Evalue=4e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023013
- InterPro:   IPR000706
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.38 [H]

Molecular weight: Translated: 35957; Mature: 35826

Theoretical pI: Translated: 6.76; Mature: 6.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARVGIYGATGYTGIELIKLLSRHPEVEIGFATARSAAGQRLSEVFPILSDLRLTAVEEV
CCEEEEECCCCCHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DPATVDLVFTCLPHNTPDLIPIVQRALAAGARVVDFSDTFRISDPQVYAARRGKEHPAPE
CCCEEEEEEEECCCCCCCHHHHHHHHHHCCCEEEECCCCEECCCCHHHHHHCCCCCCHHH
LLAQAVYGLPELHRERIRQARLVANTGCYPLTAILPLVPLVRADLLADSTVIVDSKSGVS
HHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCC
GAGRSLSLKTHFGETHETFSAYNVGRVHRHLAEMEQETGLHIIFAPHLLPVFRGILSTIY
CCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHEE
VNLKPGVDEATLAAVYADAYAAEPFVHVLPGGRLPELRHVQHTNHVVIGYQMVEPGRAIL
EEECCCCCHHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHCCCCEEEEEEEEECCCHHHH
VAVIDNLVKGAAGQAVQNMNLLLGFAETVGLMG
HHHHHHHHHCCCHHHHHHHHHHEEHHHHHCCCC
>Mature Secondary Structure 
ARVGIYGATGYTGIELIKLLSRHPEVEIGFATARSAAGQRLSEVFPILSDLRLTAVEEV
CEEEEECCCCCHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DPATVDLVFTCLPHNTPDLIPIVQRALAAGARVVDFSDTFRISDPQVYAARRGKEHPAPE
CCCEEEEEEEECCCCCCCHHHHHHHHHHCCCEEEECCCCEECCCCHHHHHHCCCCCCHHH
LLAQAVYGLPELHRERIRQARLVANTGCYPLTAILPLVPLVRADLLADSTVIVDSKSGVS
HHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCC
GAGRSLSLKTHFGETHETFSAYNVGRVHRHLAEMEQETGLHIIFAPHLLPVFRGILSTIY
CCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHEE
VNLKPGVDEATLAAVYADAYAAEPFVHVLPGGRLPELRHVQHTNHVVIGYQMVEPGRAIL
EEECCCCCHHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHCCCCEEEEEEEEECCCHHHH
VAVIDNLVKGAAGQAVQNMNLLLGFAETVGLMG
HHHHHHHHHCCCHHHHHHHHHHEEHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA