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The map label for this gene is bcc [H]

Identifier: 222526532

GI number: 222526532

Start: 4111714

End: 4112103

Strand: Reverse

Name: bcc [H]

Synonym: Chy400_3299

Alternate gene names: 222526532

Gene position: 4112103-4111714 (Counterclockwise)

Preceding gene: 222526533

Following gene: 222526531

Centisome position: 78.04

GC content: 55.13

Gene sequence:

>390_bases
ATGAAGCGCTTACGCATCACTGTCAACGGTATCACCTACGAGGTCGAAGTCGAGGTATTAGCCGACGATGACGAGCCAGC
GTTGCATGCTCCAACCAGTGTGAATGCCGTACCACCGCCACAATCGCCGACACGCACCGACTCTGCACCAAGGCCGACCT
CACCAAATCCAACCGGCCCAGGCGTGCTGGTATCACCCATTGCCGGCATCGTGGCCGAAATCAAGGTAAATGTCGGCGAT
CAGGTAAAGGAAAATGATCCGCTGGTCGTGATTGAGGCAATGAAGATGAATTCTAACGTTAGCTCACCGATTGCCGGCAC
CATCCGTGCCATCAATGTGAAAGTCGGCGACTCGGTGCGTCAAGGTCAACCACTCCTGGAGTTTGCCTGA

Upstream 100 bases:

>100_bases
CTAATCGCCAGTTACGCCGATAAGATTGCATCAGTCGTTGCAGGATATTCGCTAAACGGGCGTGTAGATCAAAAGGACGA
CCCTGCATGACGGAGAGCAT

Downstream 100 bases:

>100_bases
TGGAATGGCTGATTGGTTTTTTTGAAGCAAGCGGGATTGCCCATCTGGCATGGGGCAATCTGTTGATGATCGTCGTCGGC
TGTGTGTTCGTCTATCTGGC

Product: biotin/lipoyl attachment domain-containing protein

Products: propanoyl-CoA; CO2

Alternate protein names: BCCP [H]

Number of amino acids: Translated: 129; Mature: 129

Protein sequence:

>129_residues
MKRLRITVNGITYEVEVEVLADDDEPALHAPTSVNAVPPPQSPTRTDSAPRPTSPNPTGPGVLVSPIAGIVAEIKVNVGD
QVKENDPLVVIEAMKMNSNVSSPIAGTIRAINVKVGDSVRQGQPLLEFA

Sequences:

>Translated_129_residues
MKRLRITVNGITYEVEVEVLADDDEPALHAPTSVNAVPPPQSPTRTDSAPRPTSPNPTGPGVLVSPIAGIVAEIKVNVGD
QVKENDPLVVIEAMKMNSNVSSPIAGTIRAINVKVGDSVRQGQPLLEFA
>Mature_129_residues
MKRLRITVNGITYEVEVEVLADDDEPALHAPTSVNAVPPPQSPTRTDSAPRPTSPNPTGPGVLVSPIAGIVAEIKVNVGD
QVKENDPLVVIEAMKMNSNVSSPIAGTIRAINVKVGDSVRQGQPLLEFA

Specific function: The Pyruvate Dehydrogenase Complex Catalyzes The Overall Conversion Of Pyruvate To Acetyl-CoA And Co(2). It Contains Multiple Copies Of Three Enzymatic Components: Pyruvate Dehydrogenase (E1), Dihydrolipoamide Acetyltransferase (E2) And Lipoamide Dehydrog

COG id: COG0511

COG function: function code I; Biotin carboxyl carrier protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 biotinyl-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: 1120 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 912 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 4,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001882
- InterPro:   IPR000089
- InterPro:   IPR011053 [H]

Pfam domain/function: PF00364 Biotin_lipoyl [H]

EC number: 4.1.1.41

Molecular weight: Translated: 13584; Mature: 13584

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: PS50968 BIOTINYL_LIPOYL ; PS00188 BIOTIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRLRITVNGITYEVEVEVLADDDEPALHAPTSVNAVPPPQSPTRTDSAPRPTSPNPTGP
CCEEEEEECCEEEEEEEEEEECCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GVLVSPIAGIVAEIKVNVGDQVKENDPLVVIEAMKMNSNVSSPIAGTIRAINVKVGDSVR
CEEEHHHHCEEEEEEECCCCCCCCCCCEEEEEEEECCCCCCCCCCCEEEEEEEEECCCCC
QGQPLLEFA
CCCCCCCCC
>Mature Secondary Structure
MKRLRITVNGITYEVEVEVLADDDEPALHAPTSVNAVPPPQSPTRTDSAPRPTSPNPTGP
CCEEEEEECCEEEEEEEEEEECCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GVLVSPIAGIVAEIKVNVGDQVKENDPLVVIEAMKMNSNVSSPIAGTIRAINVKVGDSVR
CEEEHHHHCEEEEEEECCCCCCCCCCCEEEEEEEECCCCCCCCCCCEEEEEEEEECCCCC
QGQPLLEFA
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (S)-methylmalonyl-CoA

Specific reaction: (S)-methylmalonyl-CoA = propanoyl-CoA + CO2

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8431283; 12397186 [H]