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The map label for this gene is atpA

Identifier: 222526522

GI number: 222526522

Start: 4099078

End: 4100646

Strand: Reverse

Name: atpA

Synonym: Chy400_3289

Alternate gene names: 222526522

Gene position: 4100646-4099078 (Counterclockwise)

Preceding gene: 222526523

Following gene: 222526521

Centisome position: 77.83

GC content: 58.44

Gene sequence:

>1569_bases
ATGACGACGATTACTGAGGAATTGATCGCCCGGCTGAAGCAGGGGATCACGAGCGGCGTCGACCTTCAGCCGCGCCAGGT
CAATGTCGGTACGGTGATTGCCGTCGGAGACGGCGTCGCGCGGCTGTCCGGCCTTGATCAGGTCGTCGCCTCTGAGATTG
TTGAATTTCCCCCGAAAGCCGGTCGCAATGAGTCGATTTACGGTATTGCCCTGAACCTCGAACAGGATAGCGTCGCCGCC
ATTATCCTTGGTGACGATGAGACGATTGAGGAAGGGGATATGGTTACCTCAACCGGCCGGGTGATTTCGGTGCCGGTTGG
GCAGGGGTTGTTGGGACGAGTGGTGAATCCACTTGGGCAACCAATCGATGGTAAGGGGCCAATCGTCTACGAGAAGACCC
GCCCCATCGAGCGCATTGCCCCTGGTGTGATTACCCGTAAGTCGGTTGATACACCGGTGCAAACCGGTATCATTGCCATT
GACGCGCTGATTCCGATTGGACGCGGTCAGCGTGAGCTGATTATCGGTGACCGCCAGACCGGTAAGACGGCGGTGGCCAT
TGATACCATCCTCAACCAGAAGGGCCAGGGGATGGTATGTATCTACGTTGCCATTGGTCAGCGCCGGGCACAGGTTGCCC
AGGTGGTCGGAACGCTCGAACGATTTGGCGCGATGGAGTACACCATCGTCGTGTCGGCAACCGCCTCCGAGAGCGCTGCG
TTGCAGTACATCGCCCCCTACGCCGGTTGTGCGATGGGCGAAGAGATTATGGAAAACGGCGTTATGCTCAATGGGCAACT
GGTCAAGGATGCCCTGATCGTCTACGACGACCTGAGCAAGCACGCTGTTGCCTATCGCCAGGTATCTCTCTTGCTCCGCC
GCCCACCCGGCCGCGAAGCCTATCCCGGTGATGTCTTCTACCTGCACTCGCGTCTGCTTGAACGCGCCGCTCGTCTGAAT
GAAGAGTACGGTGGTGGTTCGCTGACCGCGTTGCCGGTCATCGAGACGCAGGCAAACGACGTGTCGGCCTACATTCCGAC
GAACGTCATCTCGATCACCGACGGCCAGATTTATCTGGAGTCCGACCTGTTCAATGCCGGTCAACGTCCGGCGCTCAACG
TCGGTATCTCGGTGTCGCGTGTCGGTGGTGCTGCACAGACCCGGGCAATGCGGGCAGTTGCCGGTAAGCTGAAAGGTGAG
CTGGCACAGTTCCGTGACCTGGCTGCATTCGCCCAGTTTGCCAGCGATCTCGATGCGACGACCAAAGCGCAAATCGAGCG
CGGTCAGCGTCTGCAAGAATTGCTGAAGCAACCACAGTATCAGCCGCTTCCGGTCGAAGACCAGGTAGCCGTGCTGTACG
CAGCAACCAACAACTATCTCGATGATGTACCGGTGCCGTTGATCACCAAGTGGCGCGATGACTTTCTGGCCTTCCTGCGC
ACCGCTCACCCCGAGGTGCGGAAGCTGATCTACGACAATCGCCTTGATCGCAAGTTCCCGACGCCTGAAGTGAAAGAGGC
GCTGGAAGCGGCGATTAAGGAATTTAAGGCAACCAGCAACTATAGCTAG

Upstream 100 bases:

>100_bases
CTGCGTGCCCGCCTGAGCGCCATTCAGCGTGTGTTACAGGCAAGTTAGAGTCCAGCTCGCTGGCCCGGTATCGCCGGCTA
CCAGCGCGACGGAGTAGAGC

Downstream 100 bases:

>100_bases
CAGAAGGCTACCGGCGAGCGTCCCTCTGAAGCGCTCGCCGGAATCCAGACTGCAAAGGGTTCGATATGCCGAGTAGTCGC
GAGATTAAGCGCCGCATCCG

Product: F0F1 ATP synthase subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha; F-ATPase subunit alpha

Number of amino acids: Translated: 522; Mature: 521

Protein sequence:

>522_residues
MTTITEELIARLKQGITSGVDLQPRQVNVGTVIAVGDGVARLSGLDQVVASEIVEFPPKAGRNESIYGIALNLEQDSVAA
IILGDDETIEEGDMVTSTGRVISVPVGQGLLGRVVNPLGQPIDGKGPIVYEKTRPIERIAPGVITRKSVDTPVQTGIIAI
DALIPIGRGQRELIIGDRQTGKTAVAIDTILNQKGQGMVCIYVAIGQRRAQVAQVVGTLERFGAMEYTIVVSATASESAA
LQYIAPYAGCAMGEEIMENGVMLNGQLVKDALIVYDDLSKHAVAYRQVSLLLRRPPGREAYPGDVFYLHSRLLERAARLN
EEYGGGSLTALPVIETQANDVSAYIPTNVISITDGQIYLESDLFNAGQRPALNVGISVSRVGGAAQTRAMRAVAGKLKGE
LAQFRDLAAFAQFASDLDATTKAQIERGQRLQELLKQPQYQPLPVEDQVAVLYAATNNYLDDVPVPLITKWRDDFLAFLR
TAHPEVRKLIYDNRLDRKFPTPEVKEALEAAIKEFKATSNYS

Sequences:

>Translated_522_residues
MTTITEELIARLKQGITSGVDLQPRQVNVGTVIAVGDGVARLSGLDQVVASEIVEFPPKAGRNESIYGIALNLEQDSVAA
IILGDDETIEEGDMVTSTGRVISVPVGQGLLGRVVNPLGQPIDGKGPIVYEKTRPIERIAPGVITRKSVDTPVQTGIIAI
DALIPIGRGQRELIIGDRQTGKTAVAIDTILNQKGQGMVCIYVAIGQRRAQVAQVVGTLERFGAMEYTIVVSATASESAA
LQYIAPYAGCAMGEEIMENGVMLNGQLVKDALIVYDDLSKHAVAYRQVSLLLRRPPGREAYPGDVFYLHSRLLERAARLN
EEYGGGSLTALPVIETQANDVSAYIPTNVISITDGQIYLESDLFNAGQRPALNVGISVSRVGGAAQTRAMRAVAGKLKGE
LAQFRDLAAFAQFASDLDATTKAQIERGQRLQELLKQPQYQPLPVEDQVAVLYAATNNYLDDVPVPLITKWRDDFLAFLR
TAHPEVRKLIYDNRLDRKFPTPEVKEALEAAIKEFKATSNYS
>Mature_521_residues
TTITEELIARLKQGITSGVDLQPRQVNVGTVIAVGDGVARLSGLDQVVASEIVEFPPKAGRNESIYGIALNLEQDSVAAI
ILGDDETIEEGDMVTSTGRVISVPVGQGLLGRVVNPLGQPIDGKGPIVYEKTRPIERIAPGVITRKSVDTPVQTGIIAID
ALIPIGRGQRELIIGDRQTGKTAVAIDTILNQKGQGMVCIYVAIGQRRAQVAQVVGTLERFGAMEYTIVVSATASESAAL
QYIAPYAGCAMGEEIMENGVMLNGQLVKDALIVYDDLSKHAVAYRQVSLLLRRPPGREAYPGDVFYLHSRLLERAARLNE
EYGGGSLTALPVIETQANDVSAYIPTNVISITDGQIYLESDLFNAGQRPALNVGISVSRVGGAAQTRAMRAVAGKLKGEL
AQFRDLAAFAQFASDLDATTKAQIERGQRLQELLKQPQYQPLPVEDQVAVLYAATNNYLDDVPVPLITKWRDDFLAFLRT
AHPEVRKLIYDNRLDRKFPTPEVKEALEAAIKEFKATSNYS

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family

Homologues:

Organism=Homo sapiens, GI50345984, Length=491, Percent_Identity=59.877800407332, Blast_Score=570, Evalue=1e-162,
Organism=Homo sapiens, GI4757810, Length=491, Percent_Identity=59.877800407332, Blast_Score=570, Evalue=1e-162,
Organism=Homo sapiens, GI19913426, Length=413, Percent_Identity=26.634382566586, Blast_Score=107, Evalue=4e-23,
Organism=Homo sapiens, GI19913428, Length=315, Percent_Identity=28.2539682539683, Blast_Score=105, Evalue=8e-23,
Organism=Homo sapiens, GI32189394, Length=380, Percent_Identity=24.4736842105263, Blast_Score=89, Evalue=9e-18,
Organism=Escherichia coli, GI1790172, Length=510, Percent_Identity=56.4705882352941, Blast_Score=553, Evalue=1e-159,
Organism=Escherichia coli, GI1788251, Length=345, Percent_Identity=25.7971014492754, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1790170, Length=369, Percent_Identity=24.1192411924119, Blast_Score=93, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI71988063, Length=484, Percent_Identity=59.9173553719008, Blast_Score=576, Evalue=1e-164,
Organism=Caenorhabditis elegans, GI71988080, Length=498, Percent_Identity=59.0361445783133, Blast_Score=575, Evalue=1e-164,
Organism=Caenorhabditis elegans, GI71988074, Length=484, Percent_Identity=55.7851239669422, Blast_Score=518, Evalue=1e-147,
Organism=Caenorhabditis elegans, GI17570191, Length=391, Percent_Identity=26.8542199488491, Blast_Score=108, Evalue=7e-24,
Organism=Caenorhabditis elegans, GI17510931, Length=311, Percent_Identity=26.0450160771704, Blast_Score=96, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI25144756, Length=385, Percent_Identity=23.8961038961039, Blast_Score=82, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17509265, Length=58, Percent_Identity=56.8965517241379, Blast_Score=71, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6319370, Length=526, Percent_Identity=55.1330798479088, Blast_Score=553, Evalue=1e-158,
Organism=Saccharomyces cerevisiae, GI6319603, Length=438, Percent_Identity=26.2557077625571, Blast_Score=107, Evalue=7e-24,
Organism=Saccharomyces cerevisiae, GI6322581, Length=416, Percent_Identity=25.2403846153846, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24658560, Length=525, Percent_Identity=55.6190476190476, Blast_Score=550, Evalue=1e-157,
Organism=Drosophila melanogaster, GI281361666, Length=306, Percent_Identity=28.7581699346405, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24646341, Length=306, Percent_Identity=28.7581699346405, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI17136796, Length=306, Percent_Identity=28.7581699346405, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24638766, Length=382, Percent_Identity=24.869109947644, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI28574560, Length=417, Percent_Identity=24.9400479616307, Blast_Score=80, Evalue=4e-15,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ATPA_CHLAA (A9WGS6)

Other databases:

- EMBL:   CP000909
- RefSeq:   YP_001636631.1
- ProteinModelPortal:   A9WGS6
- SMR:   A9WGS6
- GeneID:   5827517
- GenomeReviews:   CP000909_GR
- KEGG:   cau:Caur_3043
- HOGENOM:   HBG565875
- OMA:   GSDRDIK
- ProtClustDB:   PRK09281
- HAMAP:   MF_01346
- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100
- PANTHER:   PTHR15184:SF3
- TIGRFAMs:   TIGR00962

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N; SSF47917 ATPase_a/b_C; SSF50615 ATPase_a/b_N

EC number: =3.6.3.14

Molecular weight: Translated: 56508; Mature: 56377

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTITEELIARLKQGITSGVDLQPRQVNVGTVIAVGDGVARLSGLDQVVASEIVEFPPKA
CCCCHHHHHHHHHHCCCCCCCCCCCEECCEEEEEECCCHHHHHHHHHHHHHHHHHCCCCC
GRNESIYGIALNLEQDSVAAIILGDDETIEEGDMVTSTGRVISVPVGQGLLGRVVNPLGQ
CCCCCEEEEEEEECCCCEEEEEECCCCCCCCCCEEECCCCEEEEECCCCHHHHHHHHHCC
PIDGKGPIVYEKTRPIERIAPGVITRKSVDTPVQTGIIAIDALIPIGRGQRELIIGDRQT
CCCCCCCEEEECCCCHHHHCCCCEECCCCCCCHHHCEEEEEEEEECCCCCEEEEEECCCC
GKTAVAIDTILNQKGQGMVCIYVAIGQRRAQVAQVVGTLERFGAMEYTIVVSATASESAA
CCEEEEHHHHHCCCCCCEEEEEEEECCHHHHHHHHHHHHHHHCCEEEEEEEEECCCCCHH
LQYIAPYAGCAMGEEIMENGVMLNGQLVKDALIVYDDLSKHAVAYRQVSLLLRRPPGREA
HHHHHHHHHHHHHHHHHHCCEEEECHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCC
YPGDVFYLHSRLLERAARLNEEYGGGSLTALPVIETQANDVSAYIPTNVISITDGQIYLE
CCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCEEEEE
SDLFNAGQRPALNVGISVSRVGGAAQTRAMRAVAGKLKGELAQFRDLAAFAQFASDLDAT
CCHHCCCCCCEEEECEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
TKAQIERGQRLQELLKQPQYQPLPVEDQVAVLYAATNNYLDDVPVPLITKWRDDFLAFLR
HHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHH
TAHPEVRKLIYDNRLDRKFPTPEVKEALEAAIKEFKATSNYS
HCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TTITEELIARLKQGITSGVDLQPRQVNVGTVIAVGDGVARLSGLDQVVASEIVEFPPKA
CCCHHHHHHHHHHCCCCCCCCCCCEECCEEEEEECCCHHHHHHHHHHHHHHHHHCCCCC
GRNESIYGIALNLEQDSVAAIILGDDETIEEGDMVTSTGRVISVPVGQGLLGRVVNPLGQ
CCCCCEEEEEEEECCCCEEEEEECCCCCCCCCCEEECCCCEEEEECCCCHHHHHHHHHCC
PIDGKGPIVYEKTRPIERIAPGVITRKSVDTPVQTGIIAIDALIPIGRGQRELIIGDRQT
CCCCCCCEEEECCCCHHHHCCCCEECCCCCCCHHHCEEEEEEEEECCCCCEEEEEECCCC
GKTAVAIDTILNQKGQGMVCIYVAIGQRRAQVAQVVGTLERFGAMEYTIVVSATASESAA
CCEEEEHHHHHCCCCCCEEEEEEEECCHHHHHHHHHHHHHHHCCEEEEEEEEECCCCCHH
LQYIAPYAGCAMGEEIMENGVMLNGQLVKDALIVYDDLSKHAVAYRQVSLLLRRPPGREA
HHHHHHHHHHHHHHHHHHCCEEEECHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCC
YPGDVFYLHSRLLERAARLNEEYGGGSLTALPVIETQANDVSAYIPTNVISITDGQIYLE
CCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCEEEEE
SDLFNAGQRPALNVGISVSRVGGAAQTRAMRAVAGKLKGELAQFRDLAAFAQFASDLDAT
CCHHCCCCCCEEEECEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
TKAQIERGQRLQELLKQPQYQPLPVEDQVAVLYAATNNYLDDVPVPLITKWRDDFLAFLR
HHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHH
TAHPEVRKLIYDNRLDRKFPTPEVKEALEAAIKEFKATSNYS
HCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA