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The map label for this gene is aceE [H]

Identifier: 222526271

GI number: 222526271

Start: 3745767

End: 3748091

Strand: Reverse

Name: aceE [H]

Synonym: Chy400_3037

Alternate gene names: 222526271

Gene position: 3748091-3745767 (Counterclockwise)

Preceding gene: 222526274

Following gene: 222526266

Centisome position: 71.14

GC content: 58.41

Gene sequence:

>2325_bases
ATGCCCCACACTGAGCCAAACCCTGCGCTGATTAGCGCCATTGAAGAGGTGCAACAGCGCGTGCTCTGGCTGTCAACGCT
GATGATCCATCACGCTAACCATGTGCGTCCCAATCTGGATGGGGTAAAGGTGGGTGGTCATCAGGCTTCTTCTGCGTCAA
TGGTGACGATATTAACCACGTTGTATTTGTGTTATCTGCGACCTGGTGACCGGGTCTCGATTAAGCCACACGCTTCACCA
GCCTATCATGCGCTCCAGTACTTGCTCGGTCGGCTCGATGCCCGCTATCTCACGCAACTGCGGGCATTTGGCGGTTTGCA
GGCTTATCCGTCACGCACCAAAGACCCTGATGCGCCCGATTTCTCAACCGGATCGGTTGGTCTGGGGGCAGTAGCCCCGG
CCTTCGCCGCGCTCAGTGCTCACTACATTGAAGCCCACTTCGGCAAACCGGCGACCCAACGCTTCATCGCGCTGGTCGGT
GATGCTGAACTCGATGAAGGGAACGTTTGGGAGGCGGTGATCGATCCGGCGCTCGATCAGCTCGACAATCTGCTCTGGAT
CGTTGACCTTAACCGTCAGAGTCTGGATCGGGTAGTGCCTGGTATTCGCGCTGCCCATCTCAAGCGATTGTTTGCCGAGA
GCGGCTGGCGGGTGTTGGAAGCCAAATATGGTCGGCGACTTCAAGCGCTCTTTGCCCAACCGGACGGCGAGGCGCTACGT
GCGCGCATTGACGAGATGAGTAACGAGGAGTATCAGGCTCTCATTCGACTCAATGGTCGCGATCTACGTCCACGACTGAT
CAATAACGATGAGCGATTGGCCCGTCTGTTGGCACAGGTGCCTGACGATGAGTTACCGGCAACCCTGGCCAACCTGGGTG
GTCACGATGTAAGCGAACTCCTGGCGACGCTGGCCGCAGCCGATGCCGAACCGCGCCGACCAACCATCATTTTTGCCTAT
ACGATCAAAGGGTGGGGTTTACCGATTGCCGGCAATCCGCTCAACCACTCGATGCTCCTTAGCCCAGAGCAGATCGAAGC
CCTGCGCGAACAGTTTGCCATTCCACCCGGCCACGAATGGGATCGGCTGCCGGAGGATTCGCCGGGCGGGAAATTGTGCG
CGGAAGCGGCCAAACGACTCTACGGTGTGGCGACGCCCCCGCTTTCGCCACCAGCCATCCCATTACCCGATGAGATTACC
GTCCCGACCAGCGGTACAGTCAGCACCCAGGACACATTCGGACGCTTTATGGTGCGACTTGCCGACATCGCCGGCCTGCG
CGAACGCATCGTCACCGCATCACCTGATGTTTCGGTGTCTACCAACCTGGCCGGCTGGATCAACAAGACCGGTGTGTTTG
CCCGGCGCGAAGAACCAGACTTTGAAACCGAAGCCTACCGTATGTTGCGCTGGCGACGCTGGCCGGGTGGGCAGCATATC
GAGTTGGGCATCTCGGAGATGAATCTCTTTATGCTGCTGGGCATGTTCGGTATCGCCGGCGATCTCATTGGGGAGCCGCT
GATTCCGATTGGTACGGTGTACGACCCGTTTGTCTGTCGCGGGCTTGATGCCTTCATTTACGGCCTGTATTCAGGTGCAC
GCTTTATTGTTGTCGGCACACCGAGTGGCATTACGCTCTCACCTGAAGGTGGCGCCCATCAGTCATCGGTCACCGCTTCG
TTGGGGATGGAACTACCGCAACTGGCGAGTTTTGAACCCTGTTTTGCGCTTGAGACAGCCTGGCTGCTGCACGAAGCCCT
GCGCCTGTGTCTCGATCCGAACGGCTCAGCCAGCTACCTGCGCCTCTCGACCCGGCCAATCGACCAGAGTTTATTGCAAC
CCGCGCTTGATCGGTTCGGTACCGCTGAACTACGTCGGCAGGTTCTGCGTGGTGGCTACCGGCTGATCGACCGTACAGAC
TATCGCGATCAGGCGCGATCCCCACTCGTACATATTGTGACCAGTGGTGTGCTGGTTCCCGAAGCGGTGAGCGCAGCCCA
TTATTTGCAGCGGGAAGGGGTTGCCGTCAACGTCATCAACCTGACCAGTGCCCGCCGGGTTTACGAACACTGGCGGCATG
GCGACGATTTGAGCTGGCTCTTCCTGCCAGACGAACGTAAAGCACCTATCGTCACGGTGCATGACGCTGCGTCGCACGCG
CTGGCATGGCTCGGATCGGTCTTCGGCGTGCCCTTGCGAGCGCACGGAGTTGATCGTTTTGGTCAATCGGGAAGCCGCGA
TGATCTCTATCGAGCCTTCCATCTCGATTCGATGTCGATTGTCGAGAGTGCGTTTGAGCTGGTAGATGAAGTGTATAGCG
GCTGA

Upstream 100 bases:

>100_bases
AGGAAGGGGAGCACGCCACTCCCCACTCTCCCGATGAGAGCAGAGCGGAGGAATGCTATAATAGATTCGGCCCCGCACAA
TAAATGAAGAGGAGCAATGT

Downstream 100 bases:

>100_bases
TGCGGGGGTTAGGTCACGACCTGAATACGCTCACCAGATGCGGGAGTATGGCTTCTACACTGAGCGCTTGCGGCCTGTAT
GGGCAGGATCGCCGGTTTTT

Product: transketolase central subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 774; Mature: 773

Protein sequence:

>774_residues
MPHTEPNPALISAIEEVQQRVLWLSTLMIHHANHVRPNLDGVKVGGHQASSASMVTILTTLYLCYLRPGDRVSIKPHASP
AYHALQYLLGRLDARYLTQLRAFGGLQAYPSRTKDPDAPDFSTGSVGLGAVAPAFAALSAHYIEAHFGKPATQRFIALVG
DAELDEGNVWEAVIDPALDQLDNLLWIVDLNRQSLDRVVPGIRAAHLKRLFAESGWRVLEAKYGRRLQALFAQPDGEALR
ARIDEMSNEEYQALIRLNGRDLRPRLINNDERLARLLAQVPDDELPATLANLGGHDVSELLATLAAADAEPRRPTIIFAY
TIKGWGLPIAGNPLNHSMLLSPEQIEALREQFAIPPGHEWDRLPEDSPGGKLCAEAAKRLYGVATPPLSPPAIPLPDEIT
VPTSGTVSTQDTFGRFMVRLADIAGLRERIVTASPDVSVSTNLAGWINKTGVFARREEPDFETEAYRMLRWRRWPGGQHI
ELGISEMNLFMLLGMFGIAGDLIGEPLIPIGTVYDPFVCRGLDAFIYGLYSGARFIVVGTPSGITLSPEGGAHQSSVTAS
LGMELPQLASFEPCFALETAWLLHEALRLCLDPNGSASYLRLSTRPIDQSLLQPALDRFGTAELRRQVLRGGYRLIDRTD
YRDQARSPLVHIVTSGVLVPEAVSAAHYLQREGVAVNVINLTSARRVYEHWRHGDDLSWLFLPDERKAPIVTVHDAASHA
LAWLGSVFGVPLRAHGVDRFGQSGSRDDLYRAFHLDSMSIVESAFELVDEVYSG

Sequences:

>Translated_774_residues
MPHTEPNPALISAIEEVQQRVLWLSTLMIHHANHVRPNLDGVKVGGHQASSASMVTILTTLYLCYLRPGDRVSIKPHASP
AYHALQYLLGRLDARYLTQLRAFGGLQAYPSRTKDPDAPDFSTGSVGLGAVAPAFAALSAHYIEAHFGKPATQRFIALVG
DAELDEGNVWEAVIDPALDQLDNLLWIVDLNRQSLDRVVPGIRAAHLKRLFAESGWRVLEAKYGRRLQALFAQPDGEALR
ARIDEMSNEEYQALIRLNGRDLRPRLINNDERLARLLAQVPDDELPATLANLGGHDVSELLATLAAADAEPRRPTIIFAY
TIKGWGLPIAGNPLNHSMLLSPEQIEALREQFAIPPGHEWDRLPEDSPGGKLCAEAAKRLYGVATPPLSPPAIPLPDEIT
VPTSGTVSTQDTFGRFMVRLADIAGLRERIVTASPDVSVSTNLAGWINKTGVFARREEPDFETEAYRMLRWRRWPGGQHI
ELGISEMNLFMLLGMFGIAGDLIGEPLIPIGTVYDPFVCRGLDAFIYGLYSGARFIVVGTPSGITLSPEGGAHQSSVTAS
LGMELPQLASFEPCFALETAWLLHEALRLCLDPNGSASYLRLSTRPIDQSLLQPALDRFGTAELRRQVLRGGYRLIDRTD
YRDQARSPLVHIVTSGVLVPEAVSAAHYLQREGVAVNVINLTSARRVYEHWRHGDDLSWLFLPDERKAPIVTVHDAASHA
LAWLGSVFGVPLRAHGVDRFGQSGSRDDLYRAFHLDSMSIVESAFELVDEVYSG
>Mature_773_residues
PHTEPNPALISAIEEVQQRVLWLSTLMIHHANHVRPNLDGVKVGGHQASSASMVTILTTLYLCYLRPGDRVSIKPHASPA
YHALQYLLGRLDARYLTQLRAFGGLQAYPSRTKDPDAPDFSTGSVGLGAVAPAFAALSAHYIEAHFGKPATQRFIALVGD
AELDEGNVWEAVIDPALDQLDNLLWIVDLNRQSLDRVVPGIRAAHLKRLFAESGWRVLEAKYGRRLQALFAQPDGEALRA
RIDEMSNEEYQALIRLNGRDLRPRLINNDERLARLLAQVPDDELPATLANLGGHDVSELLATLAAADAEPRRPTIIFAYT
IKGWGLPIAGNPLNHSMLLSPEQIEALREQFAIPPGHEWDRLPEDSPGGKLCAEAAKRLYGVATPPLSPPAIPLPDEITV
PTSGTVSTQDTFGRFMVRLADIAGLRERIVTASPDVSVSTNLAGWINKTGVFARREEPDFETEAYRMLRWRRWPGGQHIE
LGISEMNLFMLLGMFGIAGDLIGEPLIPIGTVYDPFVCRGLDAFIYGLYSGARFIVVGTPSGITLSPEGGAHQSSVTASL
GMELPQLASFEPCFALETAWLLHEALRLCLDPNGSASYLRLSTRPIDQSLLQPALDRFGTAELRRQVLRGGYRLIDRTDY
RDQARSPLVHIVTSGVLVPEAVSAAHYLQREGVAVNVINLTSARRVYEHWRHGDDLSWLFLPDERKAPIVTVHDAASHAL
AWLGSVFGVPLRAHGVDRFGQSGSRDDLYRAFHLDSMSIVESAFELVDEVYSG

Specific function: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components:pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydroge

COG id: COG2609

COG function: function code C; Pyruvate dehydrogenase complex, dehydrogenase (E1) component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786304, Length=777, Percent_Identity=24.1956241956242, Blast_Score=182, Evalue=8e-47,

Paralogues:

None

Copy number: 1140 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 400 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 6,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004660
- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005478
- InterPro:   IPR005474 [H]

Pfam domain/function: PF00456 Transketolase_N [H]

EC number: =1.2.4.1 [H]

Molecular weight: Translated: 85145; Mature: 85014

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPHTEPNPALISAIEEVQQRVLWLSTLMIHHANHVRPNLDGVKVGGHQASSASMVTILTT
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCHHHHHHHH
LYLCYLRPGDRVSIKPHASPAYHALQYLLGRLDARYLTQLRAFGGLQAYPSRTKDPDAPD
HHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
FSTGSVGLGAVAPAFAALSAHYIEAHFGKPATQRFIALVGDAELDEGNVWEAVIDPALDQ
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
LDNLLWIVDLNRQSLDRVVPGIRAAHLKRLFAESGWRVLEAKYGRRLQALFAQPDGEALR
HCCEEEEEECCHHHHHHHCCCHHHHHHHHHHHHCCCEEEHHHHCCHHHHHHCCCCHHHHH
ARIDEMSNEEYQALIRLNGRDLRPRLINNDERLARLLAQVPDDELPATLANLGGHDVSEL
HHHHHHCCHHEEEEEEECCCCCCCHHCCCHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHH
LATLAAADAEPRRPTIIFAYTIKGWGLPIAGNPLNHSMLLSPEQIEALREQFAIPPGHEW
HHHHHHCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCEEECHHHHHHHHHHCCCCCCCCC
DRLPEDSPGGKLCAEAAKRLYGVATPPLSPPAIPLPDEITVPTSGTVSTQDTFGRFMVRL
CCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEECCCCCCCCCHHHHHHHHHHH
ADIAGLRERIVTASPDVSVSTNLAGWINKTGVFARREEPDFETEAYRMLRWRRWPGGQHI
HHHHHHHHHHEECCCCCEEECCHHHHHHCCCCEEECCCCCHHHHHHHHHHHHCCCCCCEE
ELGISEMNLFMLLGMFGIAGDLIGEPLIPIGTVYDPFVCRGLDAFIYGLYSGARFIVVGT
EEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEC
PSGITLSPEGGAHQSSVTASLGMELPQLASFEPCFALETAWLLHEALRLCLDPNGSASYL
CCCEEECCCCCCCHHHHHHHHCCCCHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEE
RLSTRPIDQSLLQPALDRFGTAELRRQVLRGGYRLIDRTDYRDQARSPLVHIVTSGVLVP
EEECCCHHHHHHHHHHHHCCHHHHHHHHHHCCCEEECCCCCHHHHCCCCEEHHHCCCHHH
EAVSAAHYLQREGVAVNVINLTSARRVYEHWRHGDDLSWLFLPDERKAPIVTVHDAASHA
HHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHCCCCCCEEEECCCCCCCCEEEEECHHHHH
LAWLGSVFGVPLRAHGVDRFGQSGSRDDLYRAFHLDSMSIVESAFELVDEVYSG
HHHHHHHHCCCHHHCCCHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PHTEPNPALISAIEEVQQRVLWLSTLMIHHANHVRPNLDGVKVGGHQASSASMVTILTT
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCHHHHHHHH
LYLCYLRPGDRVSIKPHASPAYHALQYLLGRLDARYLTQLRAFGGLQAYPSRTKDPDAPD
HHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
FSTGSVGLGAVAPAFAALSAHYIEAHFGKPATQRFIALVGDAELDEGNVWEAVIDPALDQ
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
LDNLLWIVDLNRQSLDRVVPGIRAAHLKRLFAESGWRVLEAKYGRRLQALFAQPDGEALR
HCCEEEEEECCHHHHHHHCCCHHHHHHHHHHHHCCCEEEHHHHCCHHHHHHCCCCHHHHH
ARIDEMSNEEYQALIRLNGRDLRPRLINNDERLARLLAQVPDDELPATLANLGGHDVSEL
HHHHHHCCHHEEEEEEECCCCCCCHHCCCHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHH
LATLAAADAEPRRPTIIFAYTIKGWGLPIAGNPLNHSMLLSPEQIEALREQFAIPPGHEW
HHHHHHCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCEEECHHHHHHHHHHCCCCCCCCC
DRLPEDSPGGKLCAEAAKRLYGVATPPLSPPAIPLPDEITVPTSGTVSTQDTFGRFMVRL
CCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEECCCCCCCCCHHHHHHHHHHH
ADIAGLRERIVTASPDVSVSTNLAGWINKTGVFARREEPDFETEAYRMLRWRRWPGGQHI
HHHHHHHHHHEECCCCCEEECCHHHHHHCCCCEEECCCCCHHHHHHHHHHHHCCCCCCEE
ELGISEMNLFMLLGMFGIAGDLIGEPLIPIGTVYDPFVCRGLDAFIYGLYSGARFIVVGT
EEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEC
PSGITLSPEGGAHQSSVTASLGMELPQLASFEPCFALETAWLLHEALRLCLDPNGSASYL
CCCEEECCCCCCCHHHHHHHHCCCCHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEE
RLSTRPIDQSLLQPALDRFGTAELRRQVLRGGYRLIDRTDYRDQARSPLVHIVTSGVLVP
EEECCCHHHHHHHHHHHHCCHHHHHHHHHHCCCEEECCCCCHHHHCCCCEEHHHCCCHHH
EAVSAAHYLQREGVAVNVINLTSARRVYEHWRHGDDLSWLFLPDERKAPIVTVHDAASHA
HHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHCCCCCCEEEECCCCCCCCEEEEECHHHHH
LAWLGSVFGVPLRAHGVDRFGQSGSRDDLYRAFHLDSMSIVESAFELVDEVYSG
HHHHHHHHCCCHHHCCCHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12522265 [H]