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The map label for this gene is bsaA [H]

Identifier: 222526250

GI number: 222526250

Start: 3722394

End: 3722867

Strand: Reverse

Name: bsaA [H]

Synonym: Chy400_3014

Alternate gene names: 222526250

Gene position: 3722867-3722394 (Counterclockwise)

Preceding gene: 222526251

Following gene: 222526249

Centisome position: 70.66

GC content: 51.05

Gene sequence:

>474_bases
ATGAACATCTACCAATTCACTGTACGAACCATTGATGGCGAACAGCAATCCCTCGCGGTCTATCGCAATAAGGTGCTCTT
AATCGTCAATGTAGCCAGTCATTGCGGGTTAACGCCCCAGTACGGCGATCTTGAGTCGCTCTACCGACGCTACAAAGATC
GTGGCTTTGTCGTGCTCGGTTTTCCGAGTAATCAATTCAACCAGGAACCAGACGATGAGGCGACGATTAAATCCTTCTGC
GCTCGCACGTATGCAGTGACATTCCCGCTGTTTGCCAAAGTTGAGGTGAACGGCCCCAATACTCACCCGCTCTTTGCCTA
TCTCAAGGCGCAGCAGCCAGGACTTAGCCCCGATGGCGAGATTAAGTGGAATTTCACCAAGTTTCTGGTAAATCGGAATG
GCACTGTCGTTCGGCGGTATGCCCCAACTGATACGGTCGGCGCCATTGAACGTGAATTGGTTGAGTTGTTGTAG

Upstream 100 bases:

>100_bases
ATTCTAAACTAAATCTGGCGCACATCGTTCAGGTAACGACCGTATCCGTGGTACAATCAAAGAAGAGGTTTTAAATGTTT
ATGCAACGAACTATCATCCT

Downstream 100 bases:

>100_bases
AAGTAACAACGCAGAGAATTCCCCCTTATTGCCAGACATTTCCAAACGGCGGACAAACAAACACGGCGCAGCAGTGCTGC
GCCGTGTTTCGCCATGTTTG

Product: glutathione peroxidase

Products: glutathione disulfide; H2O

Alternate protein names: NA

Number of amino acids: Translated: 157; Mature: 157

Protein sequence:

>157_residues
MNIYQFTVRTIDGEQQSLAVYRNKVLLIVNVASHCGLTPQYGDLESLYRRYKDRGFVVLGFPSNQFNQEPDDEATIKSFC
ARTYAVTFPLFAKVEVNGPNTHPLFAYLKAQQPGLSPDGEIKWNFTKFLVNRNGTVVRRYAPTDTVGAIERELVELL

Sequences:

>Translated_157_residues
MNIYQFTVRTIDGEQQSLAVYRNKVLLIVNVASHCGLTPQYGDLESLYRRYKDRGFVVLGFPSNQFNQEPDDEATIKSFC
ARTYAVTFPLFAKVEVNGPNTHPLFAYLKAQQPGLSPDGEIKWNFTKFLVNRNGTVVRRYAPTDTVGAIERELVELL
>Mature_157_residues
MNIYQFTVRTIDGEQQSLAVYRNKVLLIVNVASHCGLTPQYGDLESLYRRYKDRGFVVLGFPSNQFNQEPDDEATIKSFC
ARTYAVTFPLFAKVEVNGPNTHPLFAYLKAQQPGLSPDGEIKWNFTKFLVNRNGTVVRRYAPTDTVGAIERELVELL

Specific function: Not Essential For B12 Transport; However, It Is An Auxiliary Component Of The Transport System. [C]

COG id: COG0386

COG function: function code O; Glutathione peroxidase

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutathione peroxidase family [H]

Homologues:

Organism=Homo sapiens, GI75709200, Length=155, Percent_Identity=43.2258064516129, Blast_Score=124, Evalue=2e-29,
Organism=Homo sapiens, GI90903240, Length=155, Percent_Identity=43.2258064516129, Blast_Score=123, Evalue=5e-29,
Organism=Homo sapiens, GI15618997, Length=158, Percent_Identity=44.3037974683544, Blast_Score=120, Evalue=7e-28,
Organism=Homo sapiens, GI192455698, Length=158, Percent_Identity=37.3417721518987, Blast_Score=104, Evalue=2e-23,
Organism=Homo sapiens, GI90903238, Length=141, Percent_Identity=42.5531914893617, Blast_Score=99, Evalue=2e-21,
Organism=Homo sapiens, GI41406084, Length=182, Percent_Identity=37.3626373626374, Blast_Score=97, Evalue=5e-21,
Organism=Homo sapiens, GI4557629, Length=176, Percent_Identity=35.2272727272727, Blast_Score=91, Evalue=5e-19,
Organism=Homo sapiens, GI32967607, Length=181, Percent_Identity=34.8066298342541, Blast_Score=85, Evalue=3e-17,
Organism=Homo sapiens, GI6006001, Length=176, Percent_Identity=32.9545454545455, Blast_Score=85, Evalue=3e-17,
Organism=Homo sapiens, GI33186887, Length=176, Percent_Identity=32.3863636363636, Blast_Score=83, Evalue=1e-16,
Organism=Escherichia coli, GI1788003, Length=165, Percent_Identity=46.6666666666667, Blast_Score=147, Evalue=4e-37,
Organism=Caenorhabditis elegans, GI17506887, Length=158, Percent_Identity=44.9367088607595, Blast_Score=135, Evalue=6e-33,
Organism=Caenorhabditis elegans, GI71993584, Length=157, Percent_Identity=44.5859872611465, Blast_Score=134, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI17535473, Length=154, Percent_Identity=44.1558441558442, Blast_Score=128, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI193210707, Length=161, Percent_Identity=46.583850931677, Blast_Score=125, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI193209493, Length=164, Percent_Identity=34.1463414634146, Blast_Score=97, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17550320, Length=164, Percent_Identity=33.5365853658537, Blast_Score=97, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI71993573, Length=94, Percent_Identity=42.5531914893617, Blast_Score=76, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI71999642, Length=70, Percent_Identity=41.4285714285714, Blast_Score=64, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6319721, Length=157, Percent_Identity=46.4968152866242, Blast_Score=155, Evalue=2e-39,
Organism=Saccharomyces cerevisiae, GI6322228, Length=137, Percent_Identity=49.6350364963504, Blast_Score=148, Evalue=4e-37,
Organism=Saccharomyces cerevisiae, GI6322826, Length=155, Percent_Identity=44.5161290322581, Blast_Score=132, Evalue=2e-32,
Organism=Drosophila melanogaster, GI24656777, Length=160, Percent_Identity=46.875, Blast_Score=134, Evalue=2e-32,
Organism=Drosophila melanogaster, GI24656767, Length=160, Percent_Identity=46.875, Blast_Score=134, Evalue=3e-32,
Organism=Drosophila melanogaster, GI24656772, Length=160, Percent_Identity=46.875, Blast_Score=134, Evalue=3e-32,
Organism=Drosophila melanogaster, GI85726443, Length=144, Percent_Identity=40.2777777777778, Blast_Score=97, Evalue=5e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000889
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00255 GSHPx [H]

EC number: 1.11.1.9

Molecular weight: Translated: 17840; Mature: 17840

Theoretical pI: Translated: 8.19; Mature: 8.19

Prosite motif: PS00460 GLUTATHIONE_PEROXID_1 ; PS00763 GLUTATHIONE_PEROXID_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIYQFTVRTIDGEQQSLAVYRNKVLLIVNVASHCGLTPQYGDLESLYRRYKDRGFVVLG
CCEEEEEEEEECCCHHHEEECCCCEEEEEEEHHHCCCCCCCCCHHHHHHHHHCCCEEEEE
FPSNQFNQEPDDEATIKSFCARTYAVTFPLFAKVEVNGPNTHPLFAYLKAQQPGLSPDGE
CCCCCCCCCCCHHHHHHHHHHHHEEEEEEEEEEEEECCCCCCCEEEEEECCCCCCCCCCE
IKWNFTKFLVNRNGTVVRRYAPTDTVGAIERELVELL
EEEEEEEEEECCCCCEEEEECCCCCHHHHHHHHHHHC
>Mature Secondary Structure
MNIYQFTVRTIDGEQQSLAVYRNKVLLIVNVASHCGLTPQYGDLESLYRRYKDRGFVVLG
CCEEEEEEEEECCCHHHEEECCCCEEEEEEEHHHCCCCCCCCCHHHHHHHHHCCCEEEEE
FPSNQFNQEPDDEATIKSFCARTYAVTFPLFAKVEVNGPNTHPLFAYLKAQQPGLSPDGE
CCCCCCCCCCCHHHHHHHHHHHHEEEEEEEEEEEEECCCCCCCEEEEEECCCCCCCCCCE
IKWNFTKFLVNRNGTVVRRYAPTDTVGAIERELVELL
EEEEEEEEEECCCCCEEEEECCCCCHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: glutathione; H2O2

Specific reaction: 2 glutathione + H2O2 = glutathione disulfide + 2 H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10086841; 11058132 [H]