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The map label for this gene is 222526171

Identifier: 222526171

GI number: 222526171

Start: 3625711

End: 3626454

Strand: Reverse

Name: 222526171

Synonym: Chy400_2930

Alternate gene names: NA

Gene position: 3626454-3625711 (Counterclockwise)

Preceding gene: 222526172

Following gene: 222526170

Centisome position: 68.83

GC content: 53.9

Gene sequence:

>744_bases
ATGAATATGTTGCAAACACTCCGTGCTCTTGGCCCAATCGATCTGCGCAGTGTCTGGCGCGATAAGATGCTCTCGTGGAT
GATCTTCCTGCCGATCCTGGGAGCAATCATTCTGCGAGTTGGATTACCGCCGCTCACCGCACGTCTGCGCGCACAGTACG
CCTTCGACCTCGAACCGTGGTACCCGCTCTTCCTGAGTTATTTTTTTGTAGTGATGACACCGGCAATCTTCGGGATTATG
ATCGGCTTTCTACTGCTCGACGAAAAGGACGACCAAACGCTGAAAGCGTTGCAGGTCACGCCACTCTCGCTCAGGAACTA
TCTCGCGTATCGTATTGCCATACCCGTTGTTCTGACCATCGCCATGATGTTTATTCTCTTTCCATTGTCGGCGCTTGACG
ACATCTCAATCCCGGCGACGTTCCTCACGGCCATTGCGGCTGCGCCGATTGCGCCTGCCCTGGCCCTCTTTATGGCAGCA
CTGGCCCAGAATAAGGTGCAGGGTTTCGCGCTGATGAAGCTCGCCGGCGTTGTGCTGATCATGCCGATCTTTGCCTTTAT
CGGTGATGGACACTGGGAAGTGCTCTTTATGGTCATTCCAACCTACTGGCCGATGAAGAGCTATCTCTTGCTGAGTGATG
GTCAGATCGCCACTGCCTGGCCCTACCTGATCGCCGCAGTTGTCTACCCGGCAATCATCATCTGGTTGTTCGGGAAACGC
TTCAACCGGATAATGGTAGAATAG

Upstream 100 bases:

>100_bases
GGATCAGTATCGGATGGGTCGTCGGGCGGCACACCTTCTACCGCTTCGTGGTGACCAAAGAGGGCAGTCGGCGGCGAAGC
GTATCGTTAGCGAGGTCGTT

Downstream 100 bases:

>100_bases
GCCGGGAATCATCAGCTTAAACCTGAGCAGATGTGGTGGTTTATCAACCCGGCATCCGCCCTGATATGAACAATCGTATG
CAGCATATCGGCGTCGTTAT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 247; Mature: 247

Protein sequence:

>247_residues
MNMLQTLRALGPIDLRSVWRDKMLSWMIFLPILGAIILRVGLPPLTARLRAQYAFDLEPWYPLFLSYFFVVMTPAIFGIM
IGFLLLDEKDDQTLKALQVTPLSLRNYLAYRIAIPVVLTIAMMFILFPLSALDDISIPATFLTAIAAAPIAPALALFMAA
LAQNKVQGFALMKLAGVVLIMPIFAFIGDGHWEVLFMVIPTYWPMKSYLLLSDGQIATAWPYLIAAVVYPAIIIWLFGKR
FNRIMVE

Sequences:

>Translated_247_residues
MNMLQTLRALGPIDLRSVWRDKMLSWMIFLPILGAIILRVGLPPLTARLRAQYAFDLEPWYPLFLSYFFVVMTPAIFGIM
IGFLLLDEKDDQTLKALQVTPLSLRNYLAYRIAIPVVLTIAMMFILFPLSALDDISIPATFLTAIAAAPIAPALALFMAA
LAQNKVQGFALMKLAGVVLIMPIFAFIGDGHWEVLFMVIPTYWPMKSYLLLSDGQIATAWPYLIAAVVYPAIIIWLFGKR
FNRIMVE
>Mature_247_residues
MNMLQTLRALGPIDLRSVWRDKMLSWMIFLPILGAIILRVGLPPLTARLRAQYAFDLEPWYPLFLSYFFVVMTPAIFGIM
IGFLLLDEKDDQTLKALQVTPLSLRNYLAYRIAIPVVLTIAMMFILFPLSALDDISIPATFLTAIAAAPIAPALALFMAA
LAQNKVQGFALMKLAGVVLIMPIFAFIGDGHWEVLFMVIPTYWPMKSYLLLSDGQIATAWPYLIAAVVYPAIIIWLFGKR
FNRIMVE

Specific function: Part of the ABC transporter complex Rv2686c/Rv2687c/Rv2688c involved in fluoroquinolones export. Confers resistance to ciprofloxacin and, to a lesser extent, norfloxacin, moxifloxacin and sparfloxacin. Probably responsible for the translocation of the sub

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 27804; Mature: 27804

Theoretical pI: Translated: 9.49; Mature: 9.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.7 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.7 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNMLQTLRALGPIDLRSVWRDKMLSWMIFLPILGAIILRVGLPPLTARLRAQYAFDLEPW
CCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCH
YPLFLSYFFVVMTPAIFGIMIGFLLLDEKDDQTLKALQVTPLSLRNYLAYRIAIPVVLTI
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
AMMFILFPLSALDDISIPATFLTAIAAAPIAPALALFMAALAQNKVQGFALMKLAGVVLI
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MPIFAFIGDGHWEVLFMVIPTYWPMKSYLLLSDGQIATAWPYLIAAVVYPAIIIWLFGKR
HHHHHHHCCCCCEEEEEEECCCCCCHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
FNRIMVE
HHHHCCC
>Mature Secondary Structure
MNMLQTLRALGPIDLRSVWRDKMLSWMIFLPILGAIILRVGLPPLTARLRAQYAFDLEPW
CCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCH
YPLFLSYFFVVMTPAIFGIMIGFLLLDEKDDQTLKALQVTPLSLRNYLAYRIAIPVVLTI
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
AMMFILFPLSALDDISIPATFLTAIAAAPIAPALALFMAALAQNKVQGFALMKLAGVVLI
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MPIFAFIGDGHWEVLFMVIPTYWPMKSYLLLSDGQIATAWPYLIAAVVYPAIIIWLFGKR
HHHHHHHCCCCCEEEEEEECCCCCCHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
FNRIMVE
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]