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The map label for this gene is fruK [H]

Identifier: 222526121

GI number: 222526121

Start: 3562763

End: 3563701

Strand: Reverse

Name: fruK [H]

Synonym: Chy400_2878

Alternate gene names: 222526121

Gene position: 3563701-3562763 (Counterclockwise)

Preceding gene: 222526122

Following gene: 222526117

Centisome position: 67.64

GC content: 59.64

Gene sequence:

>939_bases
ATGATCCATTCCTCGCCATTTCTCATCATTACCCCCAATCCAGCCGTTGATCGCATTCTGATCACACCCGGCTTGCGCGT
TGGTCAGGAGCAGCGGGTACACGAGGTATTGGTTGCGGCTGGCGGTAAAGGGTTAAACGTTGGCCGGGCACTGCGTGCCC
TTGGGGTCAATGCCACGATCCGGGCACCACTCGGAGGCATCACCGGGCAGCATGTCAGTCATCTGGCCCAGAAGGAAGGT
TTGGCCCTTCACGGCAGCGTCATCAGCAATGAAACGCGTGCGTGCACCTTGATCGTCGATCCGTCACATCAGCAGGTTAC
GGTGTTAAATGAGAAGGGGCCACGGCTGACCGGTGCCGAATGGCAAACCTTTACAGCGGCAATTGTAGACGACCCGGCAC
CGTGGAATCTGATCTGCGGCAGCTTACCGCCAGGGGTTGAACCGACAGCGCTCGCGGAATTGATTAAAGAGATTCGTGAT
CAGGGACGGCACGTACTGGTCGATACGAGTGGGCCGGCACTGGCGGCAGCAGTCAGCGCCGGCCCGGATGTGGTGAAAAT
AAACAGCCAGGAACTCAGTCACTTGACCGGTATTGACTTACCAGATGAGATGAGTGTGTATCGAGCCGCCCATGCGCTTC
ATCGCCAGGGTATTGCCCGGATCGTCATCACCCTCGGTGCGGCAGGTGCTATCGGGATTGACGCGAATGGGGCGGTACGT
GCCACACCGCCAGCCATCCCGGTACACAATCCGATTGGATGCGGCGATTCCTTCTTTGCCGGGTTAACCGTTGCCCTGAG
CCGGGGACACTCTCTCGCCGATGCCATGCGCCTGGCTACCGCTTGCGGCGCTACCGACGCCCAGACACTGGAACCGGGAA
GAATTGATCCAGCCACCGTCGCCACACTCGCTGCCCAGGTACGCCTCGGCGCGTACTAG

Upstream 100 bases:

>100_bases
CTGATCCAGCGATTACCGGCTCTTGCGCTGATGGTAGCGGGTGGGCGACAGCAATACCGTCGCCCACCCAATCTCATACC
GGTTTTGCAACAGGTTCTCT

Downstream 100 bases:

>100_bases
ACCGCAGCCAAATGAGGAGGGGTGGCTCCGATCAGACGGGCCAACTGCCGCATTTGATCGGCATTTAGATAAGCACTGCG
CTGCCCGCTGGCGGTGTAGA

Product: 1-phosphofructokinase

Products: NA

Alternate protein names: Fructose 1-phosphate kinase [H]

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
MIHSSPFLIITPNPAVDRILITPGLRVGQEQRVHEVLVAAGGKGLNVGRALRALGVNATIRAPLGGITGQHVSHLAQKEG
LALHGSVISNETRACTLIVDPSHQQVTVLNEKGPRLTGAEWQTFTAAIVDDPAPWNLICGSLPPGVEPTALAELIKEIRD
QGRHVLVDTSGPALAAAVSAGPDVVKINSQELSHLTGIDLPDEMSVYRAAHALHRQGIARIVITLGAAGAIGIDANGAVR
ATPPAIPVHNPIGCGDSFFAGLTVALSRGHSLADAMRLATACGATDAQTLEPGRIDPATVATLAAQVRLGAY

Sequences:

>Translated_312_residues
MIHSSPFLIITPNPAVDRILITPGLRVGQEQRVHEVLVAAGGKGLNVGRALRALGVNATIRAPLGGITGQHVSHLAQKEG
LALHGSVISNETRACTLIVDPSHQQVTVLNEKGPRLTGAEWQTFTAAIVDDPAPWNLICGSLPPGVEPTALAELIKEIRD
QGRHVLVDTSGPALAAAVSAGPDVVKINSQELSHLTGIDLPDEMSVYRAAHALHRQGIARIVITLGAAGAIGIDANGAVR
ATPPAIPVHNPIGCGDSFFAGLTVALSRGHSLADAMRLATACGATDAQTLEPGRIDPATVATLAAQVRLGAY
>Mature_312_residues
MIHSSPFLIITPNPAVDRILITPGLRVGQEQRVHEVLVAAGGKGLNVGRALRALGVNATIRAPLGGITGQHVSHLAQKEG
LALHGSVISNETRACTLIVDPSHQQVTVLNEKGPRLTGAEWQTFTAAIVDDPAPWNLICGSLPPGVEPTALAELIKEIRD
QGRHVLVDTSGPALAAAVSAGPDVVKINSQELSHLTGIDLPDEMSVYRAAHALHRQGIARIVITLGAAGAIGIDANGAVR
ATPPAIPVHNPIGCGDSFFAGLTVALSRGHSLADAMRLATACGATDAQTLEPGRIDPATVATLAAQVRLGAY

Specific function: Unknown

COG id: COG1105

COG function: function code G; Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Escherichia coli, GI1788493, Length=305, Percent_Identity=34.0983606557377, Blast_Score=153, Evalue=1e-38,
Organism=Escherichia coli, GI1788017, Length=288, Percent_Identity=32.6388888888889, Blast_Score=126, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022463
- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR017583 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.56 [H]

Molecular weight: Translated: 32229; Mature: 32229

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIHSSPFLIITPNPAVDRILITPGLRVGQEQRVHEVLVAAGGKGLNVGRALRALGVNATI
CCCCCCEEEECCCCCCCEEEECCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHCCCEEE
RAPLGGITGQHVSHLAQKEGLALHGSVISNETRACTLIVDPSHQQVTVLNEKGPRLTGAE
ECCCCCCCHHHHHHHHHHCCCEEECCEECCCCEEEEEEECCCCCEEEEEECCCCCCCCCC
WQTFTAAIVDDPAPWNLICGSLPPGVEPTALAELIKEIRDQGRHVLVDTSGPALAAAVSA
CCEEEEEEECCCCCCEEEECCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCEEEEECC
GPDVVKINSQELSHLTGIDLPDEMSVYRAAHALHRQGIARIVITLGAAGAIGIDANGAVR
CCCEEEECHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCEEEEEEECCCCEEEECCCCCEE
ATPPAIPVHNPIGCGDSFFAGLTVALSRGHSLADAMRLATACGATDAQTLEPGRIDPATV
ECCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHH
ATLAAQVRLGAY
HHHHHHHHCCCC
>Mature Secondary Structure
MIHSSPFLIITPNPAVDRILITPGLRVGQEQRVHEVLVAAGGKGLNVGRALRALGVNATI
CCCCCCEEEECCCCCCCEEEECCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHCCCEEE
RAPLGGITGQHVSHLAQKEGLALHGSVISNETRACTLIVDPSHQQVTVLNEKGPRLTGAE
ECCCCCCCHHHHHHHHHHCCCEEECCEECCCCEEEEEEECCCCCEEEEEECCCCCCCCCC
WQTFTAAIVDDPAPWNLICGSLPPGVEPTALAELIKEIRDQGRHVLVDTSGPALAAAVSA
CCEEEEEEECCCCCCEEEECCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCEEEEECC
GPDVVKINSQELSHLTGIDLPDEMSVYRAAHALHRQGIARIVITLGAAGAIGIDANGAVR
CCCEEEECHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCEEEEEEECCCCEEEECCCCCEE
ATPPAIPVHNPIGCGDSFFAGLTVALSRGHSLADAMRLATACGATDAQTLEPGRIDPATV
ECCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHH
ATLAAQVRLGAY
HHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]