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The map label for this gene is cobQ

Identifier: 222526011

GI number: 222526011

Start: 3410794

End: 3412263

Strand: Reverse

Name: cobQ

Synonym: Chy400_2767

Alternate gene names: 222526011

Gene position: 3412263-3410794 (Counterclockwise)

Preceding gene: 222526012

Following gene: 222526010

Centisome position: 64.76

GC content: 61.22

Gene sequence:

>1470_bases
ATGCAAGCGCCTGTACTCATGGTCGTCGGAACTGCATCATCAGTTGGCAAGAGCACCCTGGTCACCGCCCTCTGCCGGTT
GGCCTATCGGCGCGGACTTCGAGTAGCACCGTTCAAAGCCCAAAACATGAGCAACAACGCTGCCGTCACCGCCGACGGCA
AAGAGATCGCCCGCAGCACGGCTGTCCAGGCCGCTGCTGCCGGCATCGCGCCGACAGTGGCGATGAATCCCATTCTCATC
AAGCCCGAAGGCCAGCGGCGCAGCCAGATCATCGTCGAAGGCCGGCCCTGGCAAAGCCTGACAGCGACCGATTTCTGGCA
ACGCAAAGCCCAGCTCTGGTCGGTCGTAACCCGCAACCTGGACCATCTGCGGGCAACGTATGATCTGGTCATCGCCGAGG
GTGCCGGTAGTCCGGTTGAACTCAACCTGAAACCGGGCGACATTGTCAATATGCGCGTTGCGCGCTATGCACAGGCTCAA
ACCATCCTGGTCGGCGACATTGATCGCGGCGGTATCTTTGCCCAATTACTGGGCACGCTTATGCTGCTCGAACCCGAAGA
ACGGCAGCTCATCACCGGTTGTATCGTGAACCGGTTTCGCGGCGATCCCTCCCTCTTCGCCGACGGCGTAACCATCCTGG
AAGAGCGCAGCGGATTGCCGGTGCTGGGAGTCATACCGTGGCTGGACGACCTGGGGCTACCCGAAGAGGATGCGGTTGCA
CTGGAGCAACCGCCGGTCGCGCCTGCCCACGGCCTGATCATCGCCGTGATTCGTCTACCCACCATTGCCAACTTCGACGA
CTTCGATCCGCTGGCCCGCGAGCCGGGTGTCGTCGTGCGCTACATCGATCACCCGCTTGAACTCACCGGTGCCGCTGCCG
TTATCCTGCCCGGCGTCAAACACACCCTCGCCGCCCGGCACTGGCTCCACGAACGCGGATTTGACAACGCACTCCGGGAA
TTCACCGGCGCCATTGTTGGTATTTGTGGCGGTTATCAACTGTTGGGTGAACGGATCAGCGATCCACTGGCGGTTGAAGG
GAGTGGCGGTGAGGCCGCCGGTCTGGGCTTACTGCCCATCGAAACCATCTTCACCACTGCCAAACAAACAACCCAGACCA
TTGCCTGCGCTCAGGTTCCCTGGGCCGGCAATGAGCCACTGCAAGGCTATGAAATCCATATGGGGCAAAGTTACCGACGC
GGCGAAGCGCCGGCATTCCTGCGCATCATCCAGCGCGGCAACACTCCCACGAGCGCCGACGATGGTTGCATCAGCTCTGA
TGGCCGGGTCTGGGGATGTTACCTGCACGGCATTTTCGCCAATGACACATTCCGGCGGGGCTGGCTTCGCCGGTTAGGCT
GGCAACCACCCACCACACCCGTGGCAAGAGCCGATCCCTTTGACCGGTTAGCCGATCATGTTGCCGCTGCGTTGGGGCCG
GCAGTACTAGACCGTTTGATGAGAAGATAG

Upstream 100 bases:

>100_bases
CGACGCCCATCCGAGAATGCCCGGTTACTGGCAGCCTGGCGCGATGTCCACGCCAGAACTCAGGTATAAGCCCGCGCTGT
TACAAACGAGAGGATTGACA

Downstream 100 bases:

>100_bases
GAGATAGGAGGTAGAAAATAGGTTGAGAAGAAGGGGCCGATTGTAGAAGAGAGGAGAGAGGAAATAGTTGGGAAGGGGGA
TGGTTGTAGAAGGTAGGAGA

Product: cobyric acid synthase

Products: ADP; phosphate; adenosylcobyric acid; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 489; Mature: 489

Protein sequence:

>489_residues
MQAPVLMVVGTASSVGKSTLVTALCRLAYRRGLRVAPFKAQNMSNNAAVTADGKEIARSTAVQAAAAGIAPTVAMNPILI
KPEGQRRSQIIVEGRPWQSLTATDFWQRKAQLWSVVTRNLDHLRATYDLVIAEGAGSPVELNLKPGDIVNMRVARYAQAQ
TILVGDIDRGGIFAQLLGTLMLLEPEERQLITGCIVNRFRGDPSLFADGVTILEERSGLPVLGVIPWLDDLGLPEEDAVA
LEQPPVAPAHGLIIAVIRLPTIANFDDFDPLAREPGVVVRYIDHPLELTGAAAVILPGVKHTLAARHWLHERGFDNALRE
FTGAIVGICGGYQLLGERISDPLAVEGSGGEAAGLGLLPIETIFTTAKQTTQTIACAQVPWAGNEPLQGYEIHMGQSYRR
GEAPAFLRIIQRGNTPTSADDGCISSDGRVWGCYLHGIFANDTFRRGWLRRLGWQPPTTPVARADPFDRLADHVAAALGP
AVLDRLMRR

Sequences:

>Translated_489_residues
MQAPVLMVVGTASSVGKSTLVTALCRLAYRRGLRVAPFKAQNMSNNAAVTADGKEIARSTAVQAAAAGIAPTVAMNPILI
KPEGQRRSQIIVEGRPWQSLTATDFWQRKAQLWSVVTRNLDHLRATYDLVIAEGAGSPVELNLKPGDIVNMRVARYAQAQ
TILVGDIDRGGIFAQLLGTLMLLEPEERQLITGCIVNRFRGDPSLFADGVTILEERSGLPVLGVIPWLDDLGLPEEDAVA
LEQPPVAPAHGLIIAVIRLPTIANFDDFDPLAREPGVVVRYIDHPLELTGAAAVILPGVKHTLAARHWLHERGFDNALRE
FTGAIVGICGGYQLLGERISDPLAVEGSGGEAAGLGLLPIETIFTTAKQTTQTIACAQVPWAGNEPLQGYEIHMGQSYRR
GEAPAFLRIIQRGNTPTSADDGCISSDGRVWGCYLHGIFANDTFRRGWLRRLGWQPPTTPVARADPFDRLADHVAAALGP
AVLDRLMRR
>Mature_489_residues
MQAPVLMVVGTASSVGKSTLVTALCRLAYRRGLRVAPFKAQNMSNNAAVTADGKEIARSTAVQAAAAGIAPTVAMNPILI
KPEGQRRSQIIVEGRPWQSLTATDFWQRKAQLWSVVTRNLDHLRATYDLVIAEGAGSPVELNLKPGDIVNMRVARYAQAQ
TILVGDIDRGGIFAQLLGTLMLLEPEERQLITGCIVNRFRGDPSLFADGVTILEERSGLPVLGVIPWLDDLGLPEEDAVA
LEQPPVAPAHGLIIAVIRLPTIANFDDFDPLAREPGVVVRYIDHPLELTGAAAVILPGVKHTLAARHWLHERGFDNALRE
FTGAIVGICGGYQLLGERISDPLAVEGSGGEAAGLGLLPIETIFTTAKQTTQTIACAQVPWAGNEPLQGYEIHMGQSYRR
GEAPAFLRIIQRGNTPTSADDGCISSDGRVWGCYLHGIFANDTFRRGWLRRLGWQPPTTPVARADPFDRLADHVAAALGP
AVLDRLMRR

Specific function: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation

COG id: COG1492

COG function: function code H; Cobyric acid synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GATase cobBQ-type domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COBQ_CHLAA (A9WIN9)

Other databases:

- EMBL:   CP000909
- RefSeq:   YP_001636155.1
- ProteinModelPortal:   A9WIN9
- GeneID:   5827029
- GenomeReviews:   CP000909_GR
- KEGG:   cau:Caur_2560
- HOGENOM:   HBG302271
- OMA:   AHTDLNP
- ProtClustDB:   PRK00784
- HAMAP:   MF_00028
- InterPro:   IPR002586
- InterPro:   IPR017929
- InterPro:   IPR004459
- InterPro:   IPR011698
- TIGRFAMs:   TIGR00313

Pfam domain/function: PF01656 CbiA; PF07685 GATase_3

EC number: 6.3.5.10

Molecular weight: Translated: 52814; Mature: 52814

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS51274 GATASE_COBBQ

Important sites: ACT_SITE 329-329 ACT_SITE 436-436

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQAPVLMVVGTASSVGKSTLVTALCRLAYRRGLRVAPFKAQNMSNNAAVTADGKEIARST
CCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCEECCCCCCCCCCCEEEEECHHHHHHHH
AVQAAAAGIAPTVAMNPILIKPEGQRRSQIIVEGRPWQSLTATDFWQRKAQLWSVVTRNL
HHHHHHHCCCCHHCCCCEEECCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHH
DHLRATYDLVIAEGAGSPVELNLKPGDIVNMRVARYAQAQTILVGDIDRGGIFAQLLGTL
HHHHHEEEEEEECCCCCCEEEEECCCCEEHHHHHHHHCCCEEEEECCCCCCHHHHHHHHH
MLLEPEERQLITGCIVNRFRGDPSLFADGVTILEERSGLPVLGVIPWLDDLGLPEEDAVA
HCCCCHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHCCCCCEEEECCCHHHCCCCCCCCEE
LEQPPVAPAHGLIIAVIRLPTIANFDDFDPLAREPGVVVRYIDHPLELTGAAAVILPGVK
CCCCCCCCCCHHEEEEECCCCCCCCCCCCCHHCCCCEEEEEECCCCHHCCCEEEEECCHH
HTLAARHWLHERGFDNALREFTGAIVGICGGYQLLGERISDPLAVEGSGGEAAGLGLLPI
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHCCCCEEEECCCCCCCCCCCCHH
ETIFTTAKQTTQTIACAQVPWAGNEPLQGYEIHMGQSYRRGEAPAFLRIIQRGNTPTSAD
HHHHHHHHHHHHEEEEEECCCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHCCCCCCCCC
DGCISSDGRVWGCYLHGIFANDTFRRGWLRRLGWQPPTTPVARADPFDRLADHVAAALGP
CCCCCCCCCEEEEEEEEEECCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
AVLDRLMRR
HHHHHHHCC
>Mature Secondary Structure
MQAPVLMVVGTASSVGKSTLVTALCRLAYRRGLRVAPFKAQNMSNNAAVTADGKEIARST
CCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCEECCCCCCCCCCCEEEEECHHHHHHHH
AVQAAAAGIAPTVAMNPILIKPEGQRRSQIIVEGRPWQSLTATDFWQRKAQLWSVVTRNL
HHHHHHHCCCCHHCCCCEEECCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHH
DHLRATYDLVIAEGAGSPVELNLKPGDIVNMRVARYAQAQTILVGDIDRGGIFAQLLGTL
HHHHHEEEEEEECCCCCCEEEEECCCCEEHHHHHHHHCCCEEEEECCCCCCHHHHHHHHH
MLLEPEERQLITGCIVNRFRGDPSLFADGVTILEERSGLPVLGVIPWLDDLGLPEEDAVA
HCCCCHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHCCCCCEEEECCCHHHCCCCCCCCEE
LEQPPVAPAHGLIIAVIRLPTIANFDDFDPLAREPGVVVRYIDHPLELTGAAAVILPGVK
CCCCCCCCCCHHEEEEECCCCCCCCCCCCCHHCCCCEEEEEECCCCHHCCCEEEEECCHH
HTLAARHWLHERGFDNALREFTGAIVGICGGYQLLGERISDPLAVEGSGGEAAGLGLLPI
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHCCCCEEEECCCCCCCCCCCCHH
ETIFTTAKQTTQTIACAQVPWAGNEPLQGYEIHMGQSYRRGEAPAFLRIIQRGNTPTSAD
HHHHHHHHHHHHEEEEEECCCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHCCCCCCCCC
DGCISSDGRVWGCYLHGIFANDTFRRGWLRRLGWQPPTTPVARADPFDRLADHVAAALGP
CCCCCCCCCEEEEEEEEEECCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
AVLDRLMRR
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; adenosylcobyrinic acid a,c-diamide; L-glutamine; H2O

Specific reaction: 4 ATP + adenosylcobyrinic acid a,c-diamide + 4 L-glutamine + 4 H2O = 4 ADP + 4 phosphate + adenosylcobyric acid + 4 L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA