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The map label for this gene is rsbRA [H]

Identifier: 222525960

GI number: 222525960

Start: 3352489

End: 3353610

Strand: Reverse

Name: rsbRA [H]

Synonym: Chy400_2716

Alternate gene names: 222525960

Gene position: 3353610-3352489 (Counterclockwise)

Preceding gene: 222525961

Following gene: 222525959

Centisome position: 63.65

GC content: 52.41

Gene sequence:

>1122_bases
ATGAATCGCTTCCGAAACTGGCTCCTACATATCGACGCAACTGACCCGGAAATCCAACGGCGCGGTAAGATTCTGGTTTC
TCTGAGTATCGGTGTGGTTATCGTGCTTTTAACTGTTGGCCTTGCCCTCACCCTTATCCAACCCACAATTGGGCGATTGA
TCAATCTGACGCTGGCAACACTGGTTTTTGTGGCATCTTTCATCCTCGGCAAAAAGGGACTTGTAACTATTGGTGGCTAT
CTGCTCATCATACTGACAACAATTGGGGCATTGAGTGGTGAAATACTTAACCCGACATCACCATTTAATGCGTTTTATCT
TGTTCCCTCCATCTTACTCGCCAGTATCCTGCTTAAACCATTTCAGATTTGGGTAGTATTAGGTCTCTGTCTTGCCAGTA
TATTTGCAATCAGCCAACTCATCCCACCAGACATCAGAACCAGTGGCAACCTCAATCTGGCATTGGCGCATCTGACAGTG
CTGCTCATCGTGAGCGCTTTTATTTCGTTTATCGGTGCGCAAAGTCTGGCCTCTGCACTTACCGAAGCCAACGAAGCCCG
CCGGCGGGCTGAAGCGGCTAATCAGCAGCTTGCCGAACTGAACAACTCACTGGAACAACGAGTGACCGAACGTACCGCTG
CGTTACAACGTCTCAGTGAAGAGCAACAAGCGACCCTGGCCCGCCTTGAAGAGAGCATTGCTGCACAACGCAATCTGCAA
CAGACCATTGCTTCTCTATCCGTACCGGTGCTTCCCGTTCGTGATGACACCATTGTGATCCCACTGGTTGGTGCTGTCAC
CACTGACCTGCTGGCTCATTTCAACAGCACAGCCCTGGACGCTACCGAACGATATGGTGCCAGGACGTTGATTATCGATC
TCACCGGTATTGCCCTACTCGATACCCTCGCTGCAGCGACAATCGTACAAACCGCGACGGCTGCTCGTTTGTTAGGTGCC
GAAACCACGCTGGTTGGCATTCGGCCAGAGGTGGCGCAAACGCTGGTGAGTCTTGGCGCATCATTTACCGGCATACGCAC
TGCTGCCACCTTGCAAACCGCGCTCTTCGCACAGCAGCGTGGCGGATCGCGGCCAGCAAGGGATGCACCGGGCGCTATTT
GA

Upstream 100 bases:

>100_bases
GCAGCAAATTGTTGTTTTTGTTAATATCGCAATTATTTCCAGATCGCACGTCTTTTTACATCACATAAAAACCATCATAA
TCACAATATGGAGTACCATT

Downstream 100 bases:

>100_bases
CAACTACCTCACGATTTCGTATAATAACGAGGCGTTGAGCGCCCAGGTGGCGGAATTGGCAGACGCGCTAGGTTGAGGGC
CTAGTGAGCTAACCACGCTC

Product: anti-sigma-factor antagonist

Products: NA

Alternate protein names: Stressosome protein rsbRA [H]

Number of amino acids: Translated: 373; Mature: 373

Protein sequence:

>373_residues
MNRFRNWLLHIDATDPEIQRRGKILVSLSIGVVIVLLTVGLALTLIQPTIGRLINLTLATLVFVASFILGKKGLVTIGGY
LLIILTTIGALSGEILNPTSPFNAFYLVPSILLASILLKPFQIWVVLGLCLASIFAISQLIPPDIRTSGNLNLALAHLTV
LLIVSAFISFIGAQSLASALTEANEARRRAEAANQQLAELNNSLEQRVTERTAALQRLSEEQQATLARLEESIAAQRNLQ
QTIASLSVPVLPVRDDTIVIPLVGAVTTDLLAHFNSTALDATERYGARTLIIDLTGIALLDTLAAATIVQTATAARLLGA
ETTLVGIRPEVAQTLVSLGASFTGIRTAATLQTALFAQQRGGSRPARDAPGAI

Sequences:

>Translated_373_residues
MNRFRNWLLHIDATDPEIQRRGKILVSLSIGVVIVLLTVGLALTLIQPTIGRLINLTLATLVFVASFILGKKGLVTIGGY
LLIILTTIGALSGEILNPTSPFNAFYLVPSILLASILLKPFQIWVVLGLCLASIFAISQLIPPDIRTSGNLNLALAHLTV
LLIVSAFISFIGAQSLASALTEANEARRRAEAANQQLAELNNSLEQRVTERTAALQRLSEEQQATLARLEESIAAQRNLQ
QTIASLSVPVLPVRDDTIVIPLVGAVTTDLLAHFNSTALDATERYGARTLIIDLTGIALLDTLAAATIVQTATAARLLGA
ETTLVGIRPEVAQTLVSLGASFTGIRTAATLQTALFAQQRGGSRPARDAPGAI
>Mature_373_residues
MNRFRNWLLHIDATDPEIQRRGKILVSLSIGVVIVLLTVGLALTLIQPTIGRLINLTLATLVFVASFILGKKGLVTIGGY
LLIILTTIGALSGEILNPTSPFNAFYLVPSILLASILLKPFQIWVVLGLCLASIFAISQLIPPDIRTSGNLNLALAHLTV
LLIVSAFISFIGAQSLASALTEANEARRRAEAANQQLAELNNSLEQRVTERTAALQRLSEEQQATLARLEESIAAQRNLQ
QTIASLSVPVLPVRDDTIVIPLVGAVTTDLLAHFNSTALDATERYGARTLIIDLTGIALLDTLAAATIVQTATAARLLGA
ETTLVGIRPEVAQTLVSLGASFTGIRTAATLQTALFAQQRGGSRPARDAPGAI

Specific function: Negative regulator of sigma-B activity. Non- phosphorylated rsbS binds to rsbT, preventing its association with rsbU. Requires any one of rsbRA, rsbRB, rsbRC or rsbRD to sequester rsbT. When rsbS and the rsbR paralog(s) are phosphorylated, they release rs

COG id: COG1366

COG function: function code T; Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014792
- InterPro:   IPR002645 [H]

Pfam domain/function: PF08678 Rsbr_N; PF01740 STAS [H]

EC number: NA

Molecular weight: Translated: 39639; Mature: 39639

Theoretical pI: Translated: 9.16; Mature: 9.16

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.3 %Met     (Translated Protein)
0.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRFRNWLLHIDATDPEIQRRGKILVSLSIGVVIVLLTVGLALTLIQPTIGRLINLTLAT
CCCHHCEEEEECCCCHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVFVASFILGKKGLVTIGGYLLIILTTIGALSGEILNPTSPFNAFYLVPSILLASILLKP
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
FQIWVVLGLCLASIFAISQLIPPDIRTSGNLNLALAHLTVLLIVSAFISFIGAQSLASAL
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TEANEARRRAEAANQQLAELNNSLEQRVTERTAALQRLSEEQQATLARLEESIAAQRNLQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QTIASLSVPVLPVRDDTIVIPLVGAVTTDLLAHFNSTALDATERYGARTLIIDLTGIALL
HHHHHHCCCEEECCCCEEEEEHHHHHHHHHHHHCCCHHHHHHHHCCCEEEEEEHHHHHHH
DTLAAATIVQTATAARLLGAETTLVGIRPEVAQTLVSLGASFTGIRTAATLQTALFAQQR
HHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHC
GGSRPARDAPGAI
CCCCCCCCCCCCC
>Mature Secondary Structure
MNRFRNWLLHIDATDPEIQRRGKILVSLSIGVVIVLLTVGLALTLIQPTIGRLINLTLAT
CCCHHCEEEEECCCCHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVFVASFILGKKGLVTIGGYLLIILTTIGALSGEILNPTSPFNAFYLVPSILLASILLKP
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
FQIWVVLGLCLASIFAISQLIPPDIRTSGNLNLALAHLTVLLIVSAFISFIGAQSLASAL
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TEANEARRRAEAANQQLAELNNSLEQRVTERTAALQRLSEEQQATLARLEESIAAQRNLQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QTIASLSVPVLPVRDDTIVIPLVGAVTTDLLAHFNSTALDATERYGARTLIIDLTGIALL
HHHHHHCCCEEECCCCEEEEEHHHHHHHHHHHHCCCHHHHHHHHCCCEEEEEEHHHHHHH
DTLAAATIVQTATAARLLGAETTLVGIRPEVAQTLVSLGASFTGIRTAATLQTALFAQQR
HHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHC
GGSRPARDAPGAI
CCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8002610; 9384377; 11157946; 10329124 [H]