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The map label for this gene is coaD

Identifier: 222525836

GI number: 222525836

Start: 3225223

End: 3225708

Strand: Direct

Name: coaD

Synonym: Chy400_2589

Alternate gene names: 222525836

Gene position: 3225223-3225708 (Clockwise)

Preceding gene: 222525835

Following gene: 222525837

Centisome position: 61.21

GC content: 53.91

Gene sequence:

>486_bases
ATGCGCATCGCTATTTACCCTGGCAGCTTCGATCCGGTTACGTATGCTCACCTCGACATTGCCCGTCGTGCAACACGAAT
TTTTGATCGTGTGATCATGGCGGTATTTGATCGACCCCAGAAGCGGTTGCTCTTTTCCACAGCCGAGCGCTTGCAACTGT
TACAGGCTGTAACTGCCGATCTGGTGAACGTTGAGGCAACCAGCTATGAGATGCTTACCGTTGAGTTTGCCCGCCAGGTT
GGGGCTTGTGCCATTGTTCGGGGACTGCGTGCCGGCAGTGACTTTGAAGCCGAGTTTCAGATGGCTCAGGTCAATCAGAC
GATTGATCCGAATATCGAAGTCGTTGTCTTGATGGCTGGACGCCAGTTTGCCCACATTAGCTCCACAGCAGTACGGGAAA
TGGCCAGCCTTGGACGTGATCCGGTTGAGTTTACGCCGCCGGTTGTTGTGGCAGCTTTACGGGAGAAATTCGCACAGAGG
GGGTGA

Upstream 100 bases:

>100_bases
CCCTGGTCTGCACCGAATCAAATTTCGACGACTGGGTGATTCGTGCTTTTCGATCTACGAATTGACATCCATGAACACGT
CCGAAACACAACAGTAACCT

Downstream 100 bases:

>100_bases
TCGCCATCGAACTGGATGATTTGATTGACGAGTTAGAAGAGGTGATCGCTGCCGGGATCCGCCTCCCCCTCAGTGGTGGG
CGAACGTTGATCGATGAGAC

Product: phosphopantetheine adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT

Number of amino acids: Translated: 161; Mature: 161

Protein sequence:

>161_residues
MRIAIYPGSFDPVTYAHLDIARRATRIFDRVIMAVFDRPQKRLLFSTAERLQLLQAVTADLVNVEATSYEMLTVEFARQV
GACAIVRGLRAGSDFEAEFQMAQVNQTIDPNIEVVVLMAGRQFAHISSTAVREMASLGRDPVEFTPPVVVAALREKFAQR
G

Sequences:

>Translated_161_residues
MRIAIYPGSFDPVTYAHLDIARRATRIFDRVIMAVFDRPQKRLLFSTAERLQLLQAVTADLVNVEATSYEMLTVEFARQV
GACAIVRGLRAGSDFEAEFQMAQVNQTIDPNIEVVVLMAGRQFAHISSTAVREMASLGRDPVEFTPPVVVAALREKFAQR
G
>Mature_161_residues
MRIAIYPGSFDPVTYAHLDIARRATRIFDRVIMAVFDRPQKRLLFSTAERLQLLQAVTADLVNVEATSYEMLTVEFARQV
GACAIVRGLRAGSDFEAEFQMAQVNQTIDPNIEVVVLMAGRQFAHISSTAVREMASLGRDPVEFTPPVVVAALREKFAQR
G

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family

Homologues:

Organism=Escherichia coli, GI1790065, Length=155, Percent_Identity=44.5161290322581, Blast_Score=136, Evalue=9e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAD_CHLAA (A9WH99)

Other databases:

- EMBL:   CP000909
- RefSeq:   YP_001636000.1
- ProteinModelPortal:   A9WH99
- SMR:   A9WH99
- GeneID:   5826866
- GenomeReviews:   CP000909_GR
- KEGG:   cau:Caur_2402
- HOGENOM:   HBG288308
- OMA:   VRQIAAM
- ProtClustDB:   PRK00168
- GO:   GO:0005737
- HAMAP:   MF_00151
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PRINTS:   PR01020
- TIGRFAMs:   TIGR01510
- TIGRFAMs:   TIGR00125

Pfam domain/function: PF01467 CTP_transf_2

EC number: =2.7.7.3

Molecular weight: Translated: 17930; Mature: 17930

Theoretical pI: Translated: 7.51; Mature: 7.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIAIYPGSFDPVTYAHLDIARRATRIFDRVIMAVFDRPQKRLLFSTAERLQLLQAVTAD
CEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
LVNVEATSYEMLTVEFARQVGACAIVRGLRAGSDFEAEFQMAQVNQTIDPNIEVVVLMAG
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCEEEEEECC
RQFAHISSTAVREMASLGRDPVEFTPPVVVAALREKFAQRG
CCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRIAIYPGSFDPVTYAHLDIARRATRIFDRVIMAVFDRPQKRLLFSTAERLQLLQAVTAD
CEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
LVNVEATSYEMLTVEFARQVGACAIVRGLRAGSDFEAEFQMAQVNQTIDPNIEVVVLMAG
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCEEEEEECC
RQFAHISSTAVREMASLGRDPVEFTPPVVVAALREKFAQRG
CCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA