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The map label for this gene is hldE [H]

Identifier: 222525790

GI number: 222525790

Start: 3195731

End: 3196732

Strand: Direct

Name: hldE [H]

Synonym: Chy400_2543

Alternate gene names: 222525790

Gene position: 3195731-3196732 (Clockwise)

Preceding gene: 222525789

Following gene: 222525796

Centisome position: 60.65

GC content: 56.09

Gene sequence:

>1002_bases
ATGACCTGTCAGGCTACTCATCTCCCCGATCCAGCGCTTCTCGCCGGGCATCGCATTATTGTGATCGGGGATATTACACT
CGACGAATATCTTTACGGTCGTGCGACACGCCTCTCCCGTGAAGCACCTATCCCGGTGCTTGAATTTTTGCGGCGGGAAA
CCATTCTCGGTGGAGCAGCCAATCCGGCTCGCAATATCGTCGCGCTCGGTTCTCAAGCCAGCCTGATTACCATTGTCGGC
AACGATGAAGAGGGCAAACACTTGCGTGATCTGCTACAGGCAGCACACATTGATGATAGCGGCGTCATTACAGTTACGGA
TCGCGTCACGACGCGCAAAACACGTATTCTGGCCGATGCCGCTCCCCGCCTGCCGCAACAGGTTGCCCGGCTGGACTATC
TCGACCGTCAGCCTTTGTCTGCTGAGATTGAAGAACAGGTGATTGCCGCACTGGCTGGACAATTACCGGGCGCAGATGCC
GTGATCTGCTCTGATTACCAGCTTGGCCTGCTCACACCGCGCGTAGTCGATGCGGTACGAACGCTTTGCCGTCAACACGA
TGTCATCTTTGCCGTTGATGCGCAAGGCCATTCACATTATTATCGCCACGCCGATCTCTTCCGTTGCAACGACGCGGAAG
CCGCTGCTGCCCTGGGTATGCCATTCATCGACGAAGCGGTGATTGCCGAGGGGGTTACCCGCCTCTATCACGATCTTGCC
GCTCATCTCGTCATTGTTACTCGTGGGCCGGCTGGATTGGTCTTGATTGGCGATCACGAACCGTATCAACATATTCCGGC
CTACCACATCAGCGAAGTGTTCGATACTACTGGTGCCGGAGATACCTTTATTGCTGTGGCAACGCTGGCCCTGGCTGCCG
GTTGTCGGGGCAGCATTGCCGCTATGTTGGCGAATATCGCTGCTGCGCTGGTTGTGCGACGGTTTGGCAACGCAGTCGTT
ACTCCTGCAGAGCTACGGGCAGCTATAGCTGCAACAAGATAA

Upstream 100 bases:

>100_bases
CGCGTTGGCATGCAACGCTTCCGTGAGGCCGTCCTTGGCAACGATGCTGCCTAGACATTGTTGGCGGCTACCGGGAAGGT
AGCCGCCTGATTCATTTCCT

Downstream 100 bases:

>100_bases
GAGCAGGCCTTGCGCCTGCTCCCTGCCACCTGCCCCTTGTGTGAACGCTGGATTATTCAAGTGTGTTCAAACGCCTAAAT
GCACTGATTGCCTCATCTTC

Product: PfkB domain-containing protein

Products: NA

Alternate protein names: D-beta-D-heptose 7-phosphate kinase; D-beta-D-heptose 7-phosphotransferase; D-beta-D-heptose 1-phosphate adenosyltransferase [H]

Number of amino acids: Translated: 333; Mature: 332

Protein sequence:

>333_residues
MTCQATHLPDPALLAGHRIIVIGDITLDEYLYGRATRLSREAPIPVLEFLRRETILGGAANPARNIVALGSQASLITIVG
NDEEGKHLRDLLQAAHIDDSGVITVTDRVTTRKTRILADAAPRLPQQVARLDYLDRQPLSAEIEEQVIAALAGQLPGADA
VICSDYQLGLLTPRVVDAVRTLCRQHDVIFAVDAQGHSHYYRHADLFRCNDAEAAAALGMPFIDEAVIAEGVTRLYHDLA
AHLVIVTRGPAGLVLIGDHEPYQHIPAYHISEVFDTTGAGDTFIAVATLALAAGCRGSIAAMLANIAAALVVRRFGNAVV
TPAELRAAIAATR

Sequences:

>Translated_333_residues
MTCQATHLPDPALLAGHRIIVIGDITLDEYLYGRATRLSREAPIPVLEFLRRETILGGAANPARNIVALGSQASLITIVG
NDEEGKHLRDLLQAAHIDDSGVITVTDRVTTRKTRILADAAPRLPQQVARLDYLDRQPLSAEIEEQVIAALAGQLPGADA
VICSDYQLGLLTPRVVDAVRTLCRQHDVIFAVDAQGHSHYYRHADLFRCNDAEAAAALGMPFIDEAVIAEGVTRLYHDLA
AHLVIVTRGPAGLVLIGDHEPYQHIPAYHISEVFDTTGAGDTFIAVATLALAAGCRGSIAAMLANIAAALVVRRFGNAVV
TPAELRAAIAATR
>Mature_332_residues
TCQATHLPDPALLAGHRIIVIGDITLDEYLYGRATRLSREAPIPVLEFLRRETILGGAANPARNIVALGSQASLITIVGN
DEEGKHLRDLLQAAHIDDSGVITVTDRVTTRKTRILADAAPRLPQQVARLDYLDRQPLSAEIEEQVIAALAGQLPGADAV
ICSDYQLGLLTPRVVDAVRTLCRQHDVIFAVDAQGHSHYYRHADLFRCNDAEAAAALGMPFIDEAVIAEGVTRLYHDLAA
HLVIVTRGPAGLVLIGDHEPYQHIPAYHISEVFDTTGAGDTFIAVATLALAAGCRGSIAAMLANIAAALVVRRFGNAVVT
PAELRAAIAATR

Specific function: Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose [H]

COG id: COG2870

COG function: function code M; ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the cytidylyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1789432, Length=318, Percent_Identity=33.6477987421384, Blast_Score=141, Evalue=6e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023030
- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR011913
- InterPro:   IPR011914
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01467 CTP_transf_2; PF00294 PfkB [H]

EC number: 2.7.-.-

Molecular weight: Translated: 35624; Mature: 35493

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: PS00583 PFKB_KINASES_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTCQATHLPDPALLAGHRIIVIGDITLDEYLYGRATRLSREAPIPVLEFLRRETILGGAA
CCCCCCCCCCHHHHHCCEEEEEECCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCC
NPARNIVALGSQASLITIVGNDEEGKHLRDLLQAAHIDDSGVITVTDRVTTRKTRILADA
CCCCCEEEECCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHH
APRLPQQVARLDYLDRQPLSAEIEEQVIAALAGQLPGADAVICSDYQLGLLTPRVVDAVR
CCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCHHHHHHHH
TLCRQHDVIFAVDAQGHSHYYRHADLFRCNDAEAAAALGMPFIDEAVIAEGVTRLYHDLA
HHHHCCCEEEEEECCCCCCHHHCCCEEECCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
AHLVIVTRGPAGLVLIGDHEPYQHIPAYHISEVFDTTGAGDTFIAVATLALAAGCRGSIA
HEEEEEEECCCCEEEEECCCCHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHH
AMLANIAAALVVRRFGNAVVTPAELRAAIAATR
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCC
>Mature Secondary Structure 
TCQATHLPDPALLAGHRIIVIGDITLDEYLYGRATRLSREAPIPVLEFLRRETILGGAA
CCCCCCCCCHHHHHCCEEEEEECCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCC
NPARNIVALGSQASLITIVGNDEEGKHLRDLLQAAHIDDSGVITVTDRVTTRKTRILADA
CCCCCEEEECCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHH
APRLPQQVARLDYLDRQPLSAEIEEQVIAALAGQLPGADAVICSDYQLGLLTPRVVDAVR
CCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCHHHHHHHH
TLCRQHDVIFAVDAQGHSHYYRHADLFRCNDAEAAAALGMPFIDEAVIAEGVTRLYHDLA
HHHHCCCEEEEEECCCCCCHHHCCCEEECCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
AHLVIVTRGPAGLVLIGDHEPYQHIPAYHISEVFDTTGAGDTFIAVATLALAAGCRGSIA
HEEEEEEECCCCEEEEECCCCHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHH
AMLANIAAALVVRRFGNAVVTPAELRAAIAATR
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA