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The map label for this gene is aspC [H]

Identifier: 222525789

GI number: 222525789

Start: 3194461

End: 3195684

Strand: Direct

Name: aspC [H]

Synonym: Chy400_2542

Alternate gene names: 222525789

Gene position: 3194461-3195684 (Clockwise)

Preceding gene: 222525786

Following gene: 222525790

Centisome position: 60.63

GC content: 59.15

Gene sequence:

>1224_bases
ATGTCTGCCAGAATGGATTACCGTTTTGCCCGCCGTCTCGCCTCGCTCGAAGCCTCAGCCACTGCTGCAATGACTGCTCG
CGTTGCCCAAATGCGCGCTGCCGGCATTAAGGTCATTTCGTTTAGTGTTGGTGAGCCTGATTTCGATACCCCCGAACCAA
TCAAGCAGGCTGCCATTGCCGGTATCCAGGCCAATCATACGCACTATACGCCGACCGGCGGAACGCTTGAGCTGCGTAAA
GTGATCGCCGCTCGCGTAAGTGCCGATCAGGGGCTTTCCTACGGGATCGGGCAGGTTACCGTCACCACCGGCGCCAAAGA
AGCGCTCTACCTCGCCTTTCAGGCCCTGTGTGACGAAGGCGATGAAGCACTTATCCCGGCACCCTACTGGGTAAGCTACG
TGGAGCAGGCGAAACTGGCCGGCGCTACTCCGGTTACTCCTCAGACCAGTGAGCAGACTGGTTTCAAACTCACTCCTGAT
CAGCTCCGCGCCAGTTTGAGTGAGCGAACACGGATCGTCGTGCTCAATTCCCCCTCGAACCCGACCGGTGCCGTCTACAG
TGCCGAGGAGCTGGCTGCGCTGGCTGCCGTGCTTCGTGATCATCCGGCGATCATCATCACCGACGAAATCTACGATGCGA
TTTCGTATGTGCCATACACTCGTCTGTTACGGGTAGCACCTGATCTCGCCGAACGAACCCTGGTGGTCAACGGTGCAGCG
AAGGCGTATGCCATGACCGGCTGGCGGGTTGGGTACGTGGCCGGGCCACAGCCGATTATCGAAGCAATTAAGGCAATTCA
GAGCCACACCAGCACCCACACATCGAGTATCTCGCAGGACGCGGCCCTGGCGGCGTATACACCCAACCCAGACATCGAAG
CAACCGTTGCCGCAATGACGGCTGAATTCCAGCGTCGGCGCGATCTGATCCTCGGTCTGCTGGCTGAAATCCCCGGTGTG
ACCTGTACTGTACCTGATGGCGCCTTCTACGTCTTCCCTAACGTAAGTGCGTTGCTCAACCGGCCACTGCGTAACGGCAA
GGTCTGCACAACCAGCGATGAACTCAACCTCTACCTGCTCGAAGAGGCACACATCGCCTGTGTCGCCGGCGAAGCCTTCG
GCGCACCCGGCTATCTACGCCTGTCGTATGCCACCGGGAGCGAGGAGATTCGCGTTGGCATGCAACGCTTCCGTGAGGCC
GTCCTTGGCAACGATGCTGCCTAG

Upstream 100 bases:

>100_bases
ATCTGCAAGTTTTCCACCTCTGGTATAATCGCCGCAAGTGTACCTGCAACACCGATGTCTGCACCAGGTTTATGAACCTA
TATCCAGACAGGAGAGCTAC

Downstream 100 bases:

>100_bases
ACATTGTTGGCGGCTACCGGGAAGGTAGCCGCCTGATTCATTTCCTATGACCTGTCAGGCTACTCATCTCCCCGATCCAG
CGCTTCTCGCCGGGCATCGC

Product: class I and II aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 407; Mature: 406

Protein sequence:

>407_residues
MSARMDYRFARRLASLEASATAAMTARVAQMRAAGIKVISFSVGEPDFDTPEPIKQAAIAGIQANHTHYTPTGGTLELRK
VIAARVSADQGLSYGIGQVTVTTGAKEALYLAFQALCDEGDEALIPAPYWVSYVEQAKLAGATPVTPQTSEQTGFKLTPD
QLRASLSERTRIVVLNSPSNPTGAVYSAEELAALAAVLRDHPAIIITDEIYDAISYVPYTRLLRVAPDLAERTLVVNGAA
KAYAMTGWRVGYVAGPQPIIEAIKAIQSHTSTHTSSISQDAALAAYTPNPDIEATVAAMTAEFQRRRDLILGLLAEIPGV
TCTVPDGAFYVFPNVSALLNRPLRNGKVCTTSDELNLYLLEEAHIACVAGEAFGAPGYLRLSYATGSEEIRVGMQRFREA
VLGNDAA

Sequences:

>Translated_407_residues
MSARMDYRFARRLASLEASATAAMTARVAQMRAAGIKVISFSVGEPDFDTPEPIKQAAIAGIQANHTHYTPTGGTLELRK
VIAARVSADQGLSYGIGQVTVTTGAKEALYLAFQALCDEGDEALIPAPYWVSYVEQAKLAGATPVTPQTSEQTGFKLTPD
QLRASLSERTRIVVLNSPSNPTGAVYSAEELAALAAVLRDHPAIIITDEIYDAISYVPYTRLLRVAPDLAERTLVVNGAA
KAYAMTGWRVGYVAGPQPIIEAIKAIQSHTSTHTSSISQDAALAAYTPNPDIEATVAAMTAEFQRRRDLILGLLAEIPGV
TCTVPDGAFYVFPNVSALLNRPLRNGKVCTTSDELNLYLLEEAHIACVAGEAFGAPGYLRLSYATGSEEIRVGMQRFREA
VLGNDAA
>Mature_406_residues
SARMDYRFARRLASLEASATAAMTARVAQMRAAGIKVISFSVGEPDFDTPEPIKQAAIAGIQANHTHYTPTGGTLELRKV
IAARVSADQGLSYGIGQVTVTTGAKEALYLAFQALCDEGDEALIPAPYWVSYVEQAKLAGATPVTPQTSEQTGFKLTPDQ
LRASLSERTRIVVLNSPSNPTGAVYSAEELAALAAVLRDHPAIIITDEIYDAISYVPYTRLLRVAPDLAERTLVVNGAAK
AYAMTGWRVGYVAGPQPIIEAIKAIQSHTSTHTSSISQDAALAAYTPNPDIEATVAAMTAEFQRRRDLILGLLAEIPGVT
CTVPDGAFYVFPNVSALLNRPLRNGKVCTTSDELNLYLLEEAHIACVAGEAFGAPGYLRLSYATGSEEIRVGMQRFREAV
LGNDAA

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713254, Length=359, Percent_Identity=29.2479108635098, Blast_Score=154, Evalue=2e-37,
Organism=Homo sapiens, GI95147551, Length=347, Percent_Identity=28.5302593659942, Blast_Score=152, Evalue=6e-37,
Organism=Homo sapiens, GI169881279, Length=347, Percent_Identity=28.5302593659942, Blast_Score=152, Evalue=6e-37,
Organism=Homo sapiens, GI56713256, Length=356, Percent_Identity=28.9325842696629, Blast_Score=149, Evalue=4e-36,
Organism=Homo sapiens, GI169881281, Length=229, Percent_Identity=27.0742358078603, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI4507369, Length=392, Percent_Identity=23.469387755102, Blast_Score=89, Evalue=6e-18,
Organism=Escherichia coli, GI1786816, Length=397, Percent_Identity=28.2115869017632, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI1788627, Length=390, Percent_Identity=27.6923076923077, Blast_Score=139, Evalue=4e-34,
Organism=Escherichia coli, GI1788722, Length=375, Percent_Identity=27.2, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1790797, Length=377, Percent_Identity=23.342175066313, Blast_Score=63, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI71994472, Length=351, Percent_Identity=27.6353276353276, Blast_Score=135, Evalue=4e-32,
Organism=Caenorhabditis elegans, GI17567369, Length=316, Percent_Identity=27.5316455696203, Blast_Score=132, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI71994476, Length=349, Percent_Identity=27.5071633237822, Blast_Score=132, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI17567663, Length=398, Percent_Identity=24.8743718592965, Blast_Score=117, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6322401, Length=310, Percent_Identity=26.1290322580645, Blast_Score=121, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6320317, Length=357, Percent_Identity=23.249299719888, Blast_Score=70, Evalue=6e-13,
Organism=Drosophila melanogaster, GI28573069, Length=324, Percent_Identity=24.6913580246914, Blast_Score=118, Evalue=9e-27,
Organism=Drosophila melanogaster, GI24646114, Length=324, Percent_Identity=24.6913580246914, Blast_Score=118, Evalue=9e-27,
Organism=Drosophila melanogaster, GI28573067, Length=324, Percent_Identity=24.6913580246914, Blast_Score=118, Evalue=9e-27,
Organism=Drosophila melanogaster, GI28573065, Length=324, Percent_Identity=24.6913580246914, Blast_Score=118, Evalue=9e-27,
Organism=Drosophila melanogaster, GI18859735, Length=367, Percent_Identity=24.5231607629428, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24641770, Length=389, Percent_Identity=24.1645244215938, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24641760, Length=389, Percent_Identity=24.1645244215938, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24641768, Length=389, Percent_Identity=24.1645244215938, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24641766, Length=389, Percent_Identity=24.1645244215938, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24641764, Length=389, Percent_Identity=24.1645244215938, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI45551451, Length=389, Percent_Identity=24.1645244215938, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43480; Mature: 43349

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSARMDYRFARRLASLEASATAAMTARVAQMRAAGIKVISFSVGEPDFDTPEPIKQAAIA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCHHHHHHHHH
GIQANHTHYTPTGGTLELRKVIAARVSADQGLSYGIGQVTVTTGAKEALYLAFQALCDEG
CEECCCCEECCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCC
DEALIPAPYWVSYVEQAKLAGATPVTPQTSEQTGFKLTPDQLRASLSERTRIVVLNSPSN
CCEEECCHHHHHHHHHHHHCCCCCCCCCCCCCCCCEECHHHHHHHHHCCEEEEEEECCCC
PTGAVYSAEELAALAAVLRDHPAIIITDEIYDAISYVPYTRLLRVAPDLAERTLVVNGAA
CCCCEECHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHCCCHHHCEEEEECCC
KAYAMTGWRVGYVAGPQPIIEAIKAIQSHTSTHTSSISQDAALAAYTPNPDIEATVAAMT
CEEEECCEEEEEECCCHHHHHHHHHHHHHCCHHHHCCCCCCEEEEECCCCCCHHHHHHHH
AEFQRRRDLILGLLAEIPGVTCTVPDGAFYVFPNVSALLNRPLRNGKVCTTSDELNLYLL
HHHHHHHHHHHHHHHHCCCCEEECCCCCEEECCCHHHHHCCCCCCCEEEEECCCCEEEEE
EEAHIACVAGEAFGAPGYLRLSYATGSEEIRVGMQRFREAVLGNDAA
ECCCEEEEECCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SARMDYRFARRLASLEASATAAMTARVAQMRAAGIKVISFSVGEPDFDTPEPIKQAAIA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCHHHHHHHHH
GIQANHTHYTPTGGTLELRKVIAARVSADQGLSYGIGQVTVTTGAKEALYLAFQALCDEG
CEECCCCEECCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCC
DEALIPAPYWVSYVEQAKLAGATPVTPQTSEQTGFKLTPDQLRASLSERTRIVVLNSPSN
CCEEECCHHHHHHHHHHHHCCCCCCCCCCCCCCCCEECHHHHHHHHHCCEEEEEEECCCC
PTGAVYSAEELAALAAVLRDHPAIIITDEIYDAISYVPYTRLLRVAPDLAERTLVVNGAA
CCCCEECHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHCCCHHHCEEEEECCC
KAYAMTGWRVGYVAGPQPIIEAIKAIQSHTSTHTSSISQDAALAAYTPNPDIEATVAAMT
CEEEECCEEEEEECCCHHHHHHHHHHHHHCCHHHHCCCCCCEEEEECCCCCCHHHHHHHH
AEFQRRRDLILGLLAEIPGVTCTVPDGAFYVFPNVSALLNRPLRNGKVCTTSDELNLYLL
HHHHHHHHHHHHHHHHCCCCEEECCCCCEEECCCHHHHHCCCCCCCEEEEECCCCEEEEE
EEAHIACVAGEAFGAPGYLRLSYATGSEEIRVGMQRFREAVLGNDAA
ECCCEEEEECCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8837436 [H]