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The map label for this gene is rsbRA [H]

Identifier: 222525785

GI number: 222525785

Start: 3190732

End: 3191802

Strand: Direct

Name: rsbRA [H]

Synonym: Chy400_2538

Alternate gene names: 222525785

Gene position: 3190732-3191802 (Clockwise)

Preceding gene: 222525784

Following gene: 222525786

Centisome position: 60.56

GC content: 53.78

Gene sequence:

>1071_bases
ATGGCAGATACACCTTCACCACTACCATCACTCTTTTCCCTGATCAGGGAAACCCTTGCTCCCGATGTCCAGCCCTTTCT
TGCCAGCAAGGCAACCCTCGTTGACATCAGCCACACCCTCGAAGATTGCATCATCCGTAATCAGTTGCCGAGTGTTATCT
TCACCGGCTTTCAAGAAAGCAGCCACTGGCGGGAGGAGACGCAACGCTATCTTGAGCTGGCCAATATTGCCAGCTCGATT
TGCATTTTTGCCGGTGGCATCCCGCCGGTACCCGAAGAGCGCCATATCGCAGTGACGCTGGCATCAGACGATCCTCTGCG
GCAGGAGTGGTTTTTGCTTGTACTGACCGAATGGTTTTGCGCTGTGTTATGCGGTCTTGATAATCAGGTACCGGTTGAGC
GTGAGGCTGACCGCAGCTTTGCCACCCTGCTCACGTTTCAGCCTGAAGTGGTGGATGCTGTTCTTAATCGTCTTATTCCC
GTTGTCGAGCGCTACCGACCTGATCGTGCTGCCGAACTGGATCATGCCCGCACCCAGTTCCCGCCGTGCAATCCACGCGG
CCCATACCTCACCCAGATTGTCGCCGATATGGTCGCTCACCTGCAACGGCGCTATGATAACCAGCGTCAGTTGACAGACC
AGCTCAAAGAGCTTAACGAGCGTCAATCTACGCTCGAAGAAACGATTGCCCAACTGGCCGCGCCGGTTGTGCCGCTGTTT
GAAGGGGTTCTGCTCATGCCGCTTGTCGGGACTATTGACTCTCGGCGAGCACAGCATGTAATGGAACACCTGCTATCAAG
TATTGCCGAACAGATGGCCGATGTTGTTATCATCGACATTACCGGTGTGCCAATGGTTGATACTGCGGTCGCTAATTATC
TGCTCCAGACCATCAGAGCTGCCCGTTTGCTTGGCGCACAAGTGATTATCACCGGTATCAGTGCCGCCATCGCTCAAACT
ATGATCAATTTGGGTATTGATCTCGGTGATGTGCGTACCCGCAGTACGTTGCGTGAAGGCATCATGACTGCACTGGAGTT
GAGTGGTATGGAAATACGACCACGTTCGTAG

Upstream 100 bases:

>100_bases
CTCAACTCATCTCACTTCGTACCAGAATCACTACCGTCCTTTGCGTCATCGTCTGGCGACATTATTGGCAACAACCGGGA
TTTCAAAAAGGGAACTGTCA

Downstream 100 bases:

>100_bases
AAGGTATTTCGCCACCCTGAACCAGCTTACATCAGTGGAAGCCACCCGGCGCTGGTGGTTCCCGTCCCCGGCGGGTGCGG
GTAAGGGTGGGTCGGGTCTG

Product: anti-sigma-factor antagonist

Products: NA

Alternate protein names: Stressosome protein rsbRA [H]

Number of amino acids: Translated: 356; Mature: 355

Protein sequence:

>356_residues
MADTPSPLPSLFSLIRETLAPDVQPFLASKATLVDISHTLEDCIIRNQLPSVIFTGFQESSHWREETQRYLELANIASSI
CIFAGGIPPVPEERHIAVTLASDDPLRQEWFLLVLTEWFCAVLCGLDNQVPVEREADRSFATLLTFQPEVVDAVLNRLIP
VVERYRPDRAAELDHARTQFPPCNPRGPYLTQIVADMVAHLQRRYDNQRQLTDQLKELNERQSTLEETIAQLAAPVVPLF
EGVLLMPLVGTIDSRRAQHVMEHLLSSIAEQMADVVIIDITGVPMVDTAVANYLLQTIRAARLLGAQVIITGISAAIAQT
MINLGIDLGDVRTRSTLREGIMTALELSGMEIRPRS

Sequences:

>Translated_356_residues
MADTPSPLPSLFSLIRETLAPDVQPFLASKATLVDISHTLEDCIIRNQLPSVIFTGFQESSHWREETQRYLELANIASSI
CIFAGGIPPVPEERHIAVTLASDDPLRQEWFLLVLTEWFCAVLCGLDNQVPVEREADRSFATLLTFQPEVVDAVLNRLIP
VVERYRPDRAAELDHARTQFPPCNPRGPYLTQIVADMVAHLQRRYDNQRQLTDQLKELNERQSTLEETIAQLAAPVVPLF
EGVLLMPLVGTIDSRRAQHVMEHLLSSIAEQMADVVIIDITGVPMVDTAVANYLLQTIRAARLLGAQVIITGISAAIAQT
MINLGIDLGDVRTRSTLREGIMTALELSGMEIRPRS
>Mature_355_residues
ADTPSPLPSLFSLIRETLAPDVQPFLASKATLVDISHTLEDCIIRNQLPSVIFTGFQESSHWREETQRYLELANIASSIC
IFAGGIPPVPEERHIAVTLASDDPLRQEWFLLVLTEWFCAVLCGLDNQVPVEREADRSFATLLTFQPEVVDAVLNRLIPV
VERYRPDRAAELDHARTQFPPCNPRGPYLTQIVADMVAHLQRRYDNQRQLTDQLKELNERQSTLEETIAQLAAPVVPLFE
GVLLMPLVGTIDSRRAQHVMEHLLSSIAEQMADVVIIDITGVPMVDTAVANYLLQTIRAARLLGAQVIITGISAAIAQTM
INLGIDLGDVRTRSTLREGIMTALELSGMEIRPRS

Specific function: Negative regulator of sigma-B activity. Non- phosphorylated rsbS binds to rsbT, preventing its association with rsbU. Requires any one of rsbRA, rsbRB, rsbRC or rsbRD to sequester rsbT. When rsbS and the rsbR paralog(s) are phosphorylated, they release rs

COG id: COG1366

COG function: function code T; Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014792
- InterPro:   IPR002645 [H]

Pfam domain/function: PF08678 Rsbr_N; PF01740 STAS [H]

EC number: NA

Molecular weight: Translated: 39617; Mature: 39486

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADTPSPLPSLFSLIRETLAPDVQPFLASKATLVDISHTLEDCIIRNQLPSVIFTGFQES
CCCCCCCHHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHHHHHHHHCHHHHHHCCCCH
SHWREETQRYLELANIASSICIFAGGIPPVPEERHIAVTLASDDPLRQEWFLLVLTEWFC
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHH
AVLCGLDNQVPVEREADRSFATLLTFQPEVVDAVLNRLIPVVERYRPDRAAELDHARTQF
HHHHCCCCCCCCCHHHCHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCC
PPCNPRGPYLTQIVADMVAHLQRRYDNQRQLTDQLKELNERQSTLEETIAQLAAPVVPLF
CCCCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EGVLLMPLVGTIDSRRAQHVMEHLLSSIAEQMADVVIIDITGVPMVDTAVANYLLQTIRA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCHHHHHHHHHHHHHHHH
ARLLGAQVIITGISAAIAQTMINLGIDLGDVRTRSTLREGIMTALELSGMEIRPRS
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
ADTPSPLPSLFSLIRETLAPDVQPFLASKATLVDISHTLEDCIIRNQLPSVIFTGFQES
CCCCCCHHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHHHHHHHHCHHHHHHCCCCH
SHWREETQRYLELANIASSICIFAGGIPPVPEERHIAVTLASDDPLRQEWFLLVLTEWFC
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHH
AVLCGLDNQVPVEREADRSFATLLTFQPEVVDAVLNRLIPVVERYRPDRAAELDHARTQF
HHHHCCCCCCCCCHHHCHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCC
PPCNPRGPYLTQIVADMVAHLQRRYDNQRQLTDQLKELNERQSTLEETIAQLAAPVVPLF
CCCCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EGVLLMPLVGTIDSRRAQHVMEHLLSSIAEQMADVVIIDITGVPMVDTAVANYLLQTIRA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCHHHHHHHHHHHHHHHH
ARLLGAQVIITGISAAIAQTMINLGIDLGDVRTRSTLREGIMTALELSGMEIRPRS
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8002610; 9384377; 11157946; 10329124 [H]