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The map label for this gene is femX [H]

Identifier: 222525770

GI number: 222525770

Start: 3171186

End: 3172244

Strand: Reverse

Name: femX [H]

Synonym: Chy400_2523

Alternate gene names: 222525770

Gene position: 3172244-3171186 (Counterclockwise)

Preceding gene: 222525771

Following gene: 222525769

Centisome position: 60.21

GC content: 59.3

Gene sequence:

>1059_bases
ATGAAGGGTCGGTGGCGGGTTGATGTTCCATCTGCCGCGCAGTGGGATGCCTTTGTTGCTTCCCATCCCCAGGGAAATGT
GTTGCAGGCCAGTCCGTGGGGTGCTCTGAAAGCCCGCTTCGGCTGGCATTGCCGACGCATCGCAGTTTACGACGACGATG
GCACTATCCGCGCCGGTGCCCAGGTGCTCTTCCGCCGCTACGCCGGCCTGGCCTTTGGTTACACACCGCGTGGTCCCCTC
CTGTCCGGCGATCCGGCGCTCGATAATCACCTGATCGATGGCATGCGTCGGCTCGGACGCCAGATGCTGGCGGTCGCGAT
CCGGCTTGAGCCAAACGTGCGTGAAGATGACGCTCAGGCTCCCCATCTCCAGACCTGGTTTACCCGACATCGGCTGGTAG
TCGCTGAACCGATCCAACCACGCAGTACGATCCTCGTTGACCTGCAACCACCTGTAGAAACCATATTTACCGCGTACTCG
AAAGGTCATCGGGCCGATATTCGGCGGGCCGAGCGCATTGGGGTGACGGTACGGACCGGCGGCGAGGCCGATCTGTCAAC
GTTCTATGATATTATGCGAGCAACCGGTGAGCGGGCCGCCTTTGCGATTCATAGCGCTGCTTACTATACGACCGCCTGGC
AGTTGCATCAGCCACATAGTTGCCTCTTGGTTGCTGAATTGAATGGCATGCCGGTCGCGTCCCATCTGGTCTTCGCCGAT
GCGCGCTACGGTCGCTACCTGTACGGTGGTTCAACAGCAGAGGGTTTACGCAGTGGTGCCAATCATCTGCTGGCGTGGCA
CGCCATGCGTTGGGCACGCGAGCAAGGGTGTATCGGTTACGACCTGTGGGGCATTCCCGATGCGCTTGGGCAAGCGGCGA
CGGTCGCTGATGAAGCTGTGCGCACAGCCCTCGAGCAGGCTGCGCAACAAGACCCGCTGATTGGTGTCTACCGCTTCAAA
AAAGGTTTTGGTGGTCGAATCGTTCGTTTTATGCCGGCTTTCGATCTGGTCCTGTTGCCATTACTCTATCCATTGGCGCG
ACGAAAGATTGGAGGATAA

Upstream 100 bases:

>100_bases
TCTTCGGCAATGCAGCAGCGATGCCGGCTGCGGTAACCGAATATGCGGCGCGTGTCGCTTCACCGACAATGCGCTATGCC
GAACGGCAATGGGTGAGTTT

Downstream 100 bases:

>100_bases
CGTCAATGACGGCAAAAACACTTGCCAGTCTCCTGAACAATGTAGCTGTCCAACGGCTAATTGGCGAACCACTCGTGCCT
GTGCAATCGCTCACCTACGA

Product: methicillin resistance protein

Products: NA

Alternate protein names: Factor essential for expression of methicillin resistance X [H]

Number of amino acids: Translated: 352; Mature: 352

Protein sequence:

>352_residues
MKGRWRVDVPSAAQWDAFVASHPQGNVLQASPWGALKARFGWHCRRIAVYDDDGTIRAGAQVLFRRYAGLAFGYTPRGPL
LSGDPALDNHLIDGMRRLGRQMLAVAIRLEPNVREDDAQAPHLQTWFTRHRLVVAEPIQPRSTILVDLQPPVETIFTAYS
KGHRADIRRAERIGVTVRTGGEADLSTFYDIMRATGERAAFAIHSAAYYTTAWQLHQPHSCLLVAELNGMPVASHLVFAD
ARYGRYLYGGSTAEGLRSGANHLLAWHAMRWAREQGCIGYDLWGIPDALGQAATVADEAVRTALEQAAQQDPLIGVYRFK
KGFGGRIVRFMPAFDLVLLPLLYPLARRKIGG

Sequences:

>Translated_352_residues
MKGRWRVDVPSAAQWDAFVASHPQGNVLQASPWGALKARFGWHCRRIAVYDDDGTIRAGAQVLFRRYAGLAFGYTPRGPL
LSGDPALDNHLIDGMRRLGRQMLAVAIRLEPNVREDDAQAPHLQTWFTRHRLVVAEPIQPRSTILVDLQPPVETIFTAYS
KGHRADIRRAERIGVTVRTGGEADLSTFYDIMRATGERAAFAIHSAAYYTTAWQLHQPHSCLLVAELNGMPVASHLVFAD
ARYGRYLYGGSTAEGLRSGANHLLAWHAMRWAREQGCIGYDLWGIPDALGQAATVADEAVRTALEQAAQQDPLIGVYRFK
KGFGGRIVRFMPAFDLVLLPLLYPLARRKIGG
>Mature_352_residues
MKGRWRVDVPSAAQWDAFVASHPQGNVLQASPWGALKARFGWHCRRIAVYDDDGTIRAGAQVLFRRYAGLAFGYTPRGPL
LSGDPALDNHLIDGMRRLGRQMLAVAIRLEPNVREDDAQAPHLQTWFTRHRLVVAEPIQPRSTILVDLQPPVETIFTAYS
KGHRADIRRAERIGVTVRTGGEADLSTFYDIMRATGERAAFAIHSAAYYTTAWQLHQPHSCLLVAELNGMPVASHLVFAD
ARYGRYLYGGSTAEGLRSGANHLLAWHAMRWAREQGCIGYDLWGIPDALGQAATVADEAVRTALEQAAQQDPLIGVYRFK
KGFGGRIVRFMPAFDLVLLPLLYPLARRKIGG

Specific function: Catalyzes the incorporation of the first glycine of the pentaglycine interpeptide bridge, which is characteristic of the S.aureus peptidoglycan. This glycine is added to the epsilon-amino group of the L-lysine of the membrane-bound lipid II intermediate (

COG id: COG2348

COG function: function code V; Uncharacterized protein involved in methicillin resistance

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the femABX family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016181
- InterPro:   IPR003447 [H]

Pfam domain/function: PF02388 FemAB [H]

EC number: NA

Molecular weight: Translated: 39064; Mature: 39064

Theoretical pI: Translated: 9.83; Mature: 9.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGRWRVDVPSAAQWDAFVASHPQGNVLQASPWGALKARFGWHCRRIAVYDDDGTIRAGA
CCCCEEECCCCCCCCCHHHHCCCCCCEEEECCCCHHHHCCCCEEEEEEEECCCCCCHHHH
QVLFRRYAGLAFGYTPRGPLLSGDPALDNHLIDGMRRLGRQMLAVAIRLEPNVREDDAQA
HHHHHHHHCCEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCC
PHLQTWFTRHRLVVAEPIQPRSTILVDLQPPVETIFTAYSKGHRADIRRAERIGVTVRTG
CHHHHHHHHCEEEEECCCCCCCEEEEECCCCHHHHHHHHCCCCHHHHHHHHHCCEEEECC
GEADLSTFYDIMRATGERAAFAIHSAAYYTTAWQLHQPHSCLLVAELNGMPVASHLVFAD
CCCHHHHHHHHHHHCCCHHEEEEEHHHHEEEEEEECCCCCEEEEEECCCCCHHHHEEEEC
ARYGRYLYGGSTAEGLRSGANHLLAWHAMRWAREQGCIGYDLWGIPDALGQAATVADEAV
CCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHH
RTALEQAAQQDPLIGVYRFKKGFGGRIVRFMPAFDLVLLPLLYPLARRKIGG
HHHHHHHHHCCCCEEEEEECCCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKGRWRVDVPSAAQWDAFVASHPQGNVLQASPWGALKARFGWHCRRIAVYDDDGTIRAGA
CCCCEEECCCCCCCCCHHHHCCCCCCEEEECCCCHHHHCCCCEEEEEEEECCCCCCHHHH
QVLFRRYAGLAFGYTPRGPLLSGDPALDNHLIDGMRRLGRQMLAVAIRLEPNVREDDAQA
HHHHHHHHCCEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCC
PHLQTWFTRHRLVVAEPIQPRSTILVDLQPPVETIFTAYSKGHRADIRRAERIGVTVRTG
CHHHHHHHHCEEEEECCCCCCCEEEEECCCCHHHHHHHHCCCCHHHHHHHHHCCEEEECC
GEADLSTFYDIMRATGERAAFAIHSAAYYTTAWQLHQPHSCLLVAELNGMPVASHLVFAD
CCCHHHHHHHHHHHCCCHHEEEEEHHHHEEEEEEECCCCCEEEEEECCCCCHHHHEEEEC
ARYGRYLYGGSTAEGLRSGANHLLAWHAMRWAREQGCIGYDLWGIPDALGQAATVADEAV
CCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHH
RTALEQAAQQDPLIGVYRFKKGFGGRIVRFMPAFDLVLLPLLYPLARRKIGG
HHHHHHHHHCCCCEEEEEECCCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA