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The map label for this gene is yrbG [H]

Identifier: 222525632

GI number: 222525632

Start: 3010625

End: 3011728

Strand: Direct

Name: yrbG [H]

Synonym: Chy400_2383

Alternate gene names: 222525632

Gene position: 3010625-3011728 (Clockwise)

Preceding gene: 222525630

Following gene: 222525634

Centisome position: 57.14

GC content: 52.99

Gene sequence:

>1104_bases
ATGGATGCCATAACAATCGGCTTGATGCTAGGCGGACTGGTTTGTCTGGCGATTGGCGGCGAGCTGTTGGTGCGTGGTGC
GAGTCACCTGGCAGCCCTGGTTGGAGTTTCACCGCTCGTCATCGGTTTGACAGTGGTCTCATTTGGTACCAGTTCACCGG
AGCTGGCGGTGAGTGTTCAGGCCGGTCTGGCCGGCAAAAGTGATATTGCGATAGGTAATGTAGTAGGGAGTAATATTTTC
AATATTCTGTTCATCCTGGGTGCCTGTGCCCTGATTAGCCCACTGATCGTTGCCGTACAACTCATTCGACGTGAAGTACC
CTTCATGATTGCGGTGTCTCTCTTGTTAGCAGTGCTGGCATTCGACGGTACGATTGGCTGGTTGGATGGATTGTTACTCT
TCAGCTTACTGCTTGGTTATACCATCTGGTCAATCTATGCCAGCCGTAAGGAGAGTGCCGCCGTGCAGGAGGAGTATGCA
CAGGAGTATGGTTCACAAAAACTGCGCGAACGCCCGACTATTGCGGTCTGGGTTATGCAGCTTGTGATGATTATTGTTGG
ATTGGGGTTACTGGCACTCGGCTCGAACTGGCTGGTCGAAAGTGCAACAGCTATTGCGCGTGCCATCGGGATTAGTGATG
TTGTGATTGGCTTGACGATTGTGGCTGCCGGTACCTCGTTACCGGAAGTCGTTGCTTCTATTGTTGCCACTCTCAAACAG
GAACGCGATATTGCGATTGGCAATGCAGTAGGGAGCAACATTTTCAATATTCTCGGTATTCTGGGGATTGCATCGCTGGT
AACACCTGGTGGTCTGGTGGTGGCGCCGTCGGTCATCACGTTTGATCTGCCGGTGATGATTGCCGTGGCCTTTGCCGTTA
TGCCGATCTTTGTTTCTGGCCTGAGCATCAACCGCTGGGAGGGGGCACTCTTTCTCGGTTATTATGTGGCGTATACAGCC
TATCTCATCCTGGCTGCGACTGAACACGATGCGTTGCCCGCGTTCAGCGGCATCATGATGCTCTTCGTCTTGCCGATCAC
GCTGCTCACCCTGGCTATTCTGACCATCAACGCCATCCGTCGGCGTGACTGGGCGACCTCGTAA

Upstream 100 bases:

>100_bases
ACAACGAAGATTCGCCCTCGCAAGGGCGATGGTTGTTACGTATAATGTATAAACGTGCATCGTGTCAAATCCTGTGCAAA
AGGAGAACATCAATAATCTT

Downstream 100 bases:

>100_bases
TGACGGTCATCATGGGGTAACGACCAGAACACCCTGTTGGGCTTCATGGCCGGGAATACGACAGTAGAAACGGTACTCTC
CAGGGGCTGGAGCGCGAAAG

Product: Na+/Ca+ antiporter

Products: Na (I) [Cytoplasm]; Ca (II) [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 367; Mature: 367

Protein sequence:

>367_residues
MDAITIGLMLGGLVCLAIGGELLVRGASHLAALVGVSPLVIGLTVVSFGTSSPELAVSVQAGLAGKSDIAIGNVVGSNIF
NILFILGACALISPLIVAVQLIRREVPFMIAVSLLLAVLAFDGTIGWLDGLLLFSLLLGYTIWSIYASRKESAAVQEEYA
QEYGSQKLRERPTIAVWVMQLVMIIVGLGLLALGSNWLVESATAIARAIGISDVVIGLTIVAAGTSLPEVVASIVATLKQ
ERDIAIGNAVGSNIFNILGILGIASLVTPGGLVVAPSVITFDLPVMIAVAFAVMPIFVSGLSINRWEGALFLGYYVAYTA
YLILAATEHDALPAFSGIMMLFVLPITLLTLAILTINAIRRRDWATS

Sequences:

>Translated_367_residues
MDAITIGLMLGGLVCLAIGGELLVRGASHLAALVGVSPLVIGLTVVSFGTSSPELAVSVQAGLAGKSDIAIGNVVGSNIF
NILFILGACALISPLIVAVQLIRREVPFMIAVSLLLAVLAFDGTIGWLDGLLLFSLLLGYTIWSIYASRKESAAVQEEYA
QEYGSQKLRERPTIAVWVMQLVMIIVGLGLLALGSNWLVESATAIARAIGISDVVIGLTIVAAGTSLPEVVASIVATLKQ
ERDIAIGNAVGSNIFNILGILGIASLVTPGGLVVAPSVITFDLPVMIAVAFAVMPIFVSGLSINRWEGALFLGYYVAYTA
YLILAATEHDALPAFSGIMMLFVLPITLLTLAILTINAIRRRDWATS
>Mature_367_residues
MDAITIGLMLGGLVCLAIGGELLVRGASHLAALVGVSPLVIGLTVVSFGTSSPELAVSVQAGLAGKSDIAIGNVVGSNIF
NILFILGACALISPLIVAVQLIRREVPFMIAVSLLLAVLAFDGTIGWLDGLLLFSLLLGYTIWSIYASRKESAAVQEEYA
QEYGSQKLRERPTIAVWVMQLVMIIVGLGLLALGSNWLVESATAIARAIGISDVVIGLTIVAAGTSLPEVVASIVATLKQ
ERDIAIGNAVGSNIFNILGILGIASLVTPGGLVVAPSVITFDLPVMIAVAFAVMPIFVSGLSINRWEGALFLGYYVAYTA
YLILAATEHDALPAFSGIMMLFVLPITLLTLAILTINAIRRRDWATS

Specific function: Unknown

COG id: COG0530

COG function: function code P; Ca2+/Na+ antiporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium/potassium/calcium exchanger family [H]

Homologues:

Organism=Homo sapiens, GI9966787, Length=151, Percent_Identity=31.7880794701987, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI300796347, Length=151, Percent_Identity=31.7880794701987, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI1789587, Length=304, Percent_Identity=35.5263157894737, Blast_Score=137, Evalue=8e-34,
Organism=Drosophila melanogaster, GI24583109, Length=132, Percent_Identity=35.6060606060606, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24583111, Length=132, Percent_Identity=35.6060606060606, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004481
- InterPro:   IPR004837 [H]

Pfam domain/function: PF01699 Na_Ca_ex [H]

EC number: NA

Molecular weight: Translated: 38373; Mature: 38373

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDAITIGLMLGGLVCLAIGGELLVRGASHLAALVGVSPLVIGLTVVSFGTSSPELAVSVQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEE
AGLAGKSDIAIGNVVGSNIFNILFILGACALISPLIVAVQLIRREVPFMIAVSLLLAVLA
CCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
FDGTIGWLDGLLLFSLLLGYTIWSIYASRKESAAVQEEYAQEYGSQKLRERPTIAVWVMQ
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
LVMIIVGLGLLALGSNWLVESATAIARAIGISDVVIGLTIVAAGTSLPEVVASIVATLKQ
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
ERDIAIGNAVGSNIFNILGILGIASLVTPGGLVVAPSVITFDLPVMIAVAFAVMPIFVSG
HCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHC
LSINRWEGALFLGYYVAYTAYLILAATEHDALPAFSGIMMLFVLPITLLTLAILTINAIR
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRDWATS
HHCCCCC
>Mature Secondary Structure
MDAITIGLMLGGLVCLAIGGELLVRGASHLAALVGVSPLVIGLTVVSFGTSSPELAVSVQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEE
AGLAGKSDIAIGNVVGSNIFNILFILGACALISPLIVAVQLIRREVPFMIAVSLLLAVLA
CCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
FDGTIGWLDGLLLFSLLLGYTIWSIYASRKESAAVQEEYAQEYGSQKLRERPTIAVWVMQ
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
LVMIIVGLGLLALGSNWLVESATAIARAIGISDVVIGLTIVAAGTSLPEVVASIVATLKQ
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
ERDIAIGNAVGSNIFNILGILGIASLVTPGGLVVAPSVITFDLPVMIAVAFAVMPIFVSG
HCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHC
LSINRWEGALFLGYYVAYTAYLILAATEHDALPAFSGIMMLFVLPITLLTLAILTINAIR
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRDWATS
HHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Periplasm]; Ca (II) [Cytoplasm] [C]

Specific reaction: Na (I) [Periplasm] + Ca (II) [Cytoplasm] = Na (I) [Cytoplasm] + Ca (II) [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]